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The map label for this gene is ftsW [H]

Identifier: 209696053

GI number: 209696053

Start: 2862311

End: 2863513

Strand: Reverse

Name: ftsW [H]

Synonym: VSAL_I2645

Alternate gene names: 209696053

Gene position: 2863513-2862311 (Counterclockwise)

Preceding gene: 209696054

Following gene: 209696052

Centisome position: 86.12

GC content: 40.07

Gene sequence:

>1203_bases
TTGGTTATTGAGCGAATTAAGCACTTAGCTTCTCCATTACAAGATTGGGTATTTACCCCATCACCTAAGGTTATGTTTGA
TCGTCAATTGATCTGGATTGCCTTGGGTTTGATGTTAACGGGTTTAGTGATGGTTGCTTCTGCTTCTTTTCCTATCAGTA
CTCGTCTGACTGGTCAGCCTTTTCATTTTATGATGCGACATATGTTATTTGTGTTTTTAGCATTAAGCATCTCCTCGATT
GTTTTACGTATAGAATTGAATAAATGGCTTAAGTACAGCAGCCATTTATTGTTAATTTCTCTTTTACTCCTTGCGGCTGT
TCTTGTTGTGGGAAAATCTGTAAATGGTGCCGCTCGTTGGTTACCTTTAGGTATTTTTAATCTACAACCAGCGGAAGTCG
CAAAACTGTCTTTATTTGTTTTTATCGCTGGGTATTTAGTTCGACGTCATGGTGAGGTTAGAGACAGTTTTCGTGGGTTT
GTTAAGCCTTTATTAGTCTTAATCACGTTGGCTTTTTTCCTTCTAATGCAGCCCGATTTAGGGACAACTGTTGTGATGTT
TGTCACTACGATTGCGATGTTGTTTATTGCTGGGGCGAAACTTTGGCAATTTATTGCGTTAGTGATGGGCGGAATTTCGT
TAGTTATCGTTCTTATTCTTGCTGAACCTTATCGTATGCGCCGAGTTACTTCTTTTCTTGACCCGTGGCAAGATCCGTTT
GGTAGTGGTTACCAATTGACGCAATCTTTGATGGCGTTTGGACGAGGTAGCTGGTTTGGTGAAGGATTAGGTAATTCGAT
TCAAAAGTTGGAATATTTACCAGAAGCTCATACTGACTTTGTATTTGCGGTTATCGCCGAAGAGCTCGGTTTTGTTGGTG
TGTGTTTGGTGTTGTGTTTGATTTTTGCACTCGTATTTAAAGCGCTTTTAATTGGTCGGAAATGTCTTGCACATGACCAA
CGATTTGGTGGTTTCTTAGCGTTTGGTATTGGTATTTGGTTTGCGTTCCAAACGTTAGTTAATGTTGGTGCTGCTGCGGG
TATTGTCCCGACAAAAGGTCTTACATTGCCATTGATCAGTTATGGCGGTTCAAGTTTAATTATTATGTCTGTTGCGGTGT
CTTTACTTATTCGTATTGATCATGAGTGTCGTGTTTATCTCGCAAACGAGCCACCTCGGAGTGAAAATGAAGAACAAAAA
TAA

Upstream 100 bases:

>100_bases
TTTCTCCTGCATGTGCCAGTTTTGATCAATATACTAACTTTATGGCAAGAGGCGATGCATTTACAGCATTAGCTAAACAC
TATTCAACTGAGAAATAATT

Downstream 100 bases:

>100_bases
ACGTTTATTAGTGATGGCTGGTGGAACGGGCGGACATGTGTTTCCTGGATTGGCTGTTGCAAAACAATTACAAAGTGAAG
GGTGGGAAATCCGCTGGCTT

Product: cell division protein FtsW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MVIERIKHLASPLQDWVFTPSPKVMFDRQLIWIALGLMLTGLVMVASASFPISTRLTGQPFHFMMRHMLFVFLALSISSI
VLRIELNKWLKYSSHLLLISLLLLAAVLVVGKSVNGAARWLPLGIFNLQPAEVAKLSLFVFIAGYLVRRHGEVRDSFRGF
VKPLLVLITLAFFLLMQPDLGTTVVMFVTTIAMLFIAGAKLWQFIALVMGGISLVIVLILAEPYRMRRVTSFLDPWQDPF
GSGYQLTQSLMAFGRGSWFGEGLGNSIQKLEYLPEAHTDFVFAVIAEELGFVGVCLVLCLIFALVFKALLIGRKCLAHDQ
RFGGFLAFGIGIWFAFQTLVNVGAAAGIVPTKGLTLPLISYGGSSLIIMSVAVSLLIRIDHECRVYLANEPPRSENEEQK

Sequences:

>Translated_400_residues
MVIERIKHLASPLQDWVFTPSPKVMFDRQLIWIALGLMLTGLVMVASASFPISTRLTGQPFHFMMRHMLFVFLALSISSI
VLRIELNKWLKYSSHLLLISLLLLAAVLVVGKSVNGAARWLPLGIFNLQPAEVAKLSLFVFIAGYLVRRHGEVRDSFRGF
VKPLLVLITLAFFLLMQPDLGTTVVMFVTTIAMLFIAGAKLWQFIALVMGGISLVIVLILAEPYRMRRVTSFLDPWQDPF
GSGYQLTQSLMAFGRGSWFGEGLGNSIQKLEYLPEAHTDFVFAVIAEELGFVGVCLVLCLIFALVFKALLIGRKCLAHDQ
RFGGFLAFGIGIWFAFQTLVNVGAAAGIVPTKGLTLPLISYGGSSLIIMSVAVSLLIRIDHECRVYLANEPPRSENEEQK
>Mature_400_residues
MVIERIKHLASPLQDWVFTPSPKVMFDRQLIWIALGLMLTGLVMVASASFPISTRLTGQPFHFMMRHMLFVFLALSISSI
VLRIELNKWLKYSSHLLLISLLLLAAVLVVGKSVNGAARWLPLGIFNLQPAEVAKLSLFVFIAGYLVRRHGEVRDSFRGF
VKPLLVLITLAFFLLMQPDLGTTVVMFVTTIAMLFIAGAKLWQFIALVMGGISLVIVLILAEPYRMRRVTSFLDPWQDPF
GSGYQLTQSLMAFGRGSWFGEGLGNSIQKLEYLPEAHTDFVFAVIAEELGFVGVCLVLCLIFALVFKALLIGRKCLAHDQ
RFGGFLAFGIGIWFAFQTLVNVGAAAGIVPTKGLTLPLISYGGSSLIIMSVAVSLLIRIDHECRVYLANEPPRSENEEQK

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=386, Percent_Identity=60.6217616580311, Blast_Score=468, Evalue=1e-133,
Organism=Escherichia coli, GI1786853, Length=343, Percent_Identity=33.8192419825073, Blast_Score=157, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 44368; Mature: 44368

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCC
>Mature Secondary Structure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CCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]