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The map label for this gene is murG

Identifier: 209696052

GI number: 209696052

Start: 2861263

End: 2862327

Strand: Reverse

Name: murG

Synonym: VSAL_I2644

Alternate gene names: 209696052

Gene position: 2862327-2861263 (Counterclockwise)

Preceding gene: 209696053

Following gene: 209696051

Centisome position: 86.08

GC content: 43.47

Gene sequence:

>1065_bases
ATGAAGAACAAAAATAAACGTTTATTAGTGATGGCTGGTGGAACGGGCGGACATGTGTTTCCTGGATTGGCTGTTGCAAA
ACAATTACAAAGTGAAGGGTGGGAAATCCGCTGGCTTGGAACAGAAGATCGAATGGAAGCTGATCTCGTACCAAAACACG
GTATTGAAATCGATTTCATTAAAGTGAAAGGATTACGCGGGCAAGGGCTTAAAAAACTATTAATCGCTCCTTTTCAAATT
ATTGGTGCTATTTTACAAGCAAAAAAACACATTCAAGCATGGCAGCCCGATGTCGTTTTAGGCATGGGGGGCTATGTGAG
TGGTCCTGGTGGCATTGCGGCGTGGTTATCTGGTATTCCGGTTGTATTGCATGAACAAAATGCTGTTGCTGGCTTAACCA
ATCAGTGGTTATCTAAAATTGCTAAACGGGTATTTCAAGCATTTCCGGGTGCTTTTCCAAATGCCGACGTTGTAGGTAAT
CCAGTAAGAGAAGATGTATGTCAACTGCCTCATCCAAGCGAACGATTTGCAGAGCGTAACGGACCTATTCGCGTATTAAT
CATGGGTGGCAGTCAAGGTGCCCGTATTCTTAATGCGACATTGCCAGAAGTATTGCCAAAACTGAATCACTCTGTTGAAA
TTTGGCATCAAGCAGGTAAAGGCAATCAAGAAACCGTTAATAATGCCTATAAAGACAATGGGATTACTGACGCGAAGGTG
ACTGAGTTTATTGATGATGTTGCTGCGGCTTATGCATGGGCTGATGTATTGGTGTGTCGCTCTGGTGCGTTAACGGTATC
CGAAGTGTCAGCGGCAGGTGTCGGCTCTGTATTTATTCCCTTTATGCACAAAGATCGCCAGCAAGCATTGAACGCAGATC
ACCTTGTACAGTGTGGCGCAGCGAAAATGATAGAACAACAAGATTTAACAGTTCAGAGTTTGGTTGATACACTGAACGGT
TTAGAGCGACCTAAGTTATTAGAAATGGCATGTAATGCCCGTAATGCAGCTATTATTGATGCAGATGTACGTGTTGCCAC
TGCGATTAAAAGCCTCGCTAAATAA

Upstream 100 bases:

>100_bases
GGTTCAAGTTTAATTATTATGTCTGTTGCGGTGTCTTTACTTATTCGTATTGATCATGAGTGTCGTGTTTATCTCGCAAA
CGAGCCACCTCGGAGTGAAA

Downstream 100 bases:

>100_bases
AAGAATTGAGATTAAAAAATGACAACAGAACAGAAACTACAATTAGCTGAAATTAGAACGATGATCCCTGAAATGCGCCG
TGTTGAATGCATCCACTTTG

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MKNKNKRLLVMAGGTGGHVFPGLAVAKQLQSEGWEIRWLGTEDRMEADLVPKHGIEIDFIKVKGLRGQGLKKLLIAPFQI
IGAILQAKKHIQAWQPDVVLGMGGYVSGPGGIAAWLSGIPVVLHEQNAVAGLTNQWLSKIAKRVFQAFPGAFPNADVVGN
PVREDVCQLPHPSERFAERNGPIRVLIMGGSQGARILNATLPEVLPKLNHSVEIWHQAGKGNQETVNNAYKDNGITDAKV
TEFIDDVAAAYAWADVLVCRSGALTVSEVSAAGVGSVFIPFMHKDRQQALNADHLVQCGAAKMIEQQDLTVQSLVDTLNG
LERPKLLEMACNARNAAIIDADVRVATAIKSLAK

Sequences:

>Translated_354_residues
MKNKNKRLLVMAGGTGGHVFPGLAVAKQLQSEGWEIRWLGTEDRMEADLVPKHGIEIDFIKVKGLRGQGLKKLLIAPFQI
IGAILQAKKHIQAWQPDVVLGMGGYVSGPGGIAAWLSGIPVVLHEQNAVAGLTNQWLSKIAKRVFQAFPGAFPNADVVGN
PVREDVCQLPHPSERFAERNGPIRVLIMGGSQGARILNATLPEVLPKLNHSVEIWHQAGKGNQETVNNAYKDNGITDAKV
TEFIDDVAAAYAWADVLVCRSGALTVSEVSAAGVGSVFIPFMHKDRQQALNADHLVQCGAAKMIEQQDLTVQSLVDTLNG
LERPKLLEMACNARNAAIIDADVRVATAIKSLAK
>Mature_354_residues
MKNKNKRLLVMAGGTGGHVFPGLAVAKQLQSEGWEIRWLGTEDRMEADLVPKHGIEIDFIKVKGLRGQGLKKLLIAPFQI
IGAILQAKKHIQAWQPDVVLGMGGYVSGPGGIAAWLSGIPVVLHEQNAVAGLTNQWLSKIAKRVFQAFPGAFPNADVVGN
PVREDVCQLPHPSERFAERNGPIRVLIMGGSQGARILNATLPEVLPKLNHSVEIWHQAGKGNQETVNNAYKDNGITDAKV
TEFIDDVAAAYAWADVLVCRSGALTVSEVSAAGVGSVFIPFMHKDRQQALNADHLVQCGAAKMIEQQDLTVQSLVDTLNG
LERPKLLEMACNARNAAIIDADVRVATAIKSLAK

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=354, Percent_Identity=64.9717514124294, Blast_Score=478, Evalue=1e-136,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_ALISL (B6ELH5)

Other databases:

- EMBL:   FM178379
- RefSeq:   YP_002263982.1
- ProteinModelPortal:   B6ELH5
- GeneID:   6988860
- GenomeReviews:   FM178379_GR
- KEGG:   vsa:VSAL_I2644
- HOGENOM:   HBG617076
- OMA:   IGFGGYP
- ProtClustDB:   PRK00726
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 38128; Mature: 38128

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNKNKRLLVMAGGTGGHVFPGLAVAKQLQSEGWEIRWLGTEDRMEADLVPKHGIEIDFI
CCCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCEEEEE
KVKGLRGQGLKKLLIAPFQIIGAILQAKKHIQAWQPDVVLGMGGYVSGPGGIAAWLSGIP
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEECCCCHHHHHHCCCC
VVLHEQNAVAGLTNQWLSKIAKRVFQAFPGAFPNADVVGNPVREDVCQLPHPSERFAERN
EEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCCCHHHHHHCC
GPIRVLIMGGSQGARILNATLPEVLPKLNHSVEIWHQAGKGNQETVNNAYKDNGITDAKV
CCEEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEHHHCCCCCHHHHHHHHHCCCCCHHHH
TEFIDDVAAAYAWADVLVCRSGALTVSEVSAAGVGSVFIPFMHKDRQQALNADHLVQCGA
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHCCHHHHCCHHHHHHHHH
AKMIEQQDLTVQSLVDTLNGLERPKLLEMACNARNAAIIDADVRVATAIKSLAK
HHHHHHHCCHHHHHHHHHHCCCCCHHHHHHCCCCCCEEEECCHHHHHHHHHHCC
>Mature Secondary Structure
MKNKNKRLLVMAGGTGGHVFPGLAVAKQLQSEGWEIRWLGTEDRMEADLVPKHGIEIDFI
CCCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCEEEEE
KVKGLRGQGLKKLLIAPFQIIGAILQAKKHIQAWQPDVVLGMGGYVSGPGGIAAWLSGIP
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEECCCCHHHHHHCCCC
VVLHEQNAVAGLTNQWLSKIAKRVFQAFPGAFPNADVVGNPVREDVCQLPHPSERFAERN
EEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCCCHHHHHHCC
GPIRVLIMGGSQGARILNATLPEVLPKLNHSVEIWHQAGKGNQETVNNAYKDNGITDAKV
CCEEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEHHHCCCCCHHHHHHHHHCCCCCHHHH
TEFIDDVAAAYAWADVLVCRSGALTVSEVSAAGVGSVFIPFMHKDRQQALNADHLVQCGA
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHCCHHHHCCHHHHHHHHH
AKMIEQQDLTVQSLVDTLNGLERPKLLEMACNARNAAIIDADVRVATAIKSLAK
HHHHHHHCCHHHHHHHHHHCCCCCHHHHHHCCCCCCEEEECCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA