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The map label for this gene is fabF [H]

Identifier: 209695536

GI number: 209695536

Start: 2241856

End: 2243061

Strand: Reverse

Name: fabF [H]

Synonym: VSAL_I2092

Alternate gene names: 209695536

Gene position: 2243061-2241856 (Counterclockwise)

Preceding gene: 209695537

Following gene: 209695535

Centisome position: 67.46

GC content: 42.04

Gene sequence:

>1206_bases
ATGGATAAAAGTAAGATGAGTGATTTTCCTGTATATATTCATGCTTGTGGTTCGCATTCAGCATTAGGCAAAGAGAGCAA
TGATATTCATCAGGCTCTCAATGGTAATCAAGGGTCTTCGATGATGCTTGAAGATGGATGGCTTAATGATGGCAAGAAAA
CCGTGGTGGGGAAGGCTGAAGGTGAACTCCCTAGCATTCCCGCTCATTTGTCCTTATTTGATACTCGAAATAACCAGTTA
GTTTTATCCGCATTGCAGCAAATAGAACCTCAAATTAAAGAAGCGAAAGCCAAGTACGGATCGGATCGAATTGCCGTTAT
TGTTGGGACAAGTACATCGGGTATTTCTGATGGCGAAGCTGCATTAAGTGAAAAGCTAAATTCCGGTATTTTTCCTGATG
ATTACCATTATCGTAAACAAGAGTTAGGAAACCCGGCTGAATTTGTGGCGACGTATTTAGAGTTGTCAGGACCGACGTAT
GCTATTTCAACGGCATGCTCTTCAAGTGGTCGAGTTTTCTTATCAGCAAAGCGATTATTGAAATCAGGGTTTGTTGATGC
GGTTATTGTGGGCGGAACGGATTCTCTGTGTAAATTAACATTGAATGGTTTTAATAGCCTAGAAGCCTTATCTAATGAAC
ACTGCTTGCCATTTAGCCCTAATCGAAAAGGCATTAATATTGGCGAAGCGAGTGCTTACATGTTGTTAAGCGCAGAGCAA
AAAGACTCCAATGATCCTATTGCCTTACTTGGCGCAGGAGACAGCTCAGATGCACATCATATTTCAGCGCCGCACCCTGA
AGGGAAAGGGGCGATTGAATCGATGCAAAAAGCATTACATGATGCCGGTCTTCACGCATCAGATATTGGGTATATCAACG
CGCATGGTACGGCAACACCATTGAATGATGCCATGGAATCGAAAGCCGTAAATGCGGTGTTTGGTTCTCATACGCCGATA
AGCTCAACCAAACCATTTACTGGGCATACATTAGGGGCGGCAGGTATTATAGAGGCTGCGATTTGTTGGCACATCTTAAA
ATACGACTTACCGTTACCAAGACAAATCAATGATAATCAAAAAGATGAAACGTTAGCGGATATAAAGTTAGTGACTGACC
AACGATTAGAAAAACCAGCGATTATCAGTAATTCATTTGCATTTGGTGGCAACAACATCAGCTTAATTTTTGGGTACCAG
TCATGA

Upstream 100 bases:

>100_bases
AAATTAAGTGGCGATATTATTTTAACGAGCCCGCATCTGGGGTATGTTATTACAATCAAAACGTTTGCAAACGCTCAGTC
TGTCATGACTAAAAAGAAGA

Downstream 100 bases:

>100_bases
GACATATTCCAGCGTTAATCGATCTTCTTCCTCATGAAACGCCGTTAGCGTTAGTGGATGAATTGATCGAAGTCAGTGAG
TTATCGATTCATTGCCAAGT

Product: 3-oxoacyl-(acyl carrier protein) synthase I

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MDKSKMSDFPVYIHACGSHSALGKESNDIHQALNGNQGSSMMLEDGWLNDGKKTVVGKAEGELPSIPAHLSLFDTRNNQL
VLSALQQIEPQIKEAKAKYGSDRIAVIVGTSTSGISDGEAALSEKLNSGIFPDDYHYRKQELGNPAEFVATYLELSGPTY
AISTACSSSGRVFLSAKRLLKSGFVDAVIVGGTDSLCKLTLNGFNSLEALSNEHCLPFSPNRKGINIGEASAYMLLSAEQ
KDSNDPIALLGAGDSSDAHHISAPHPEGKGAIESMQKALHDAGLHASDIGYINAHGTATPLNDAMESKAVNAVFGSHTPI
SSTKPFTGHTLGAAGIIEAAICWHILKYDLPLPRQINDNQKDETLADIKLVTDQRLEKPAIISNSFAFGGNNISLIFGYQ
S

Sequences:

>Translated_401_residues
MDKSKMSDFPVYIHACGSHSALGKESNDIHQALNGNQGSSMMLEDGWLNDGKKTVVGKAEGELPSIPAHLSLFDTRNNQL
VLSALQQIEPQIKEAKAKYGSDRIAVIVGTSTSGISDGEAALSEKLNSGIFPDDYHYRKQELGNPAEFVATYLELSGPTY
AISTACSSSGRVFLSAKRLLKSGFVDAVIVGGTDSLCKLTLNGFNSLEALSNEHCLPFSPNRKGINIGEASAYMLLSAEQ
KDSNDPIALLGAGDSSDAHHISAPHPEGKGAIESMQKALHDAGLHASDIGYINAHGTATPLNDAMESKAVNAVFGSHTPI
SSTKPFTGHTLGAAGIIEAAICWHILKYDLPLPRQINDNQKDETLADIKLVTDQRLEKPAIISNSFAFGGNNISLIFGYQ
S
>Mature_401_residues
MDKSKMSDFPVYIHACGSHSALGKESNDIHQALNGNQGSSMMLEDGWLNDGKKTVVGKAEGELPSIPAHLSLFDTRNNQL
VLSALQQIEPQIKEAKAKYGSDRIAVIVGTSTSGISDGEAALSEKLNSGIFPDDYHYRKQELGNPAEFVATYLELSGPTY
AISTACSSSGRVFLSAKRLLKSGFVDAVIVGGTDSLCKLTLNGFNSLEALSNEHCLPFSPNRKGINIGEASAYMLLSAEQ
KDSNDPIALLGAGDSSDAHHISAPHPEGKGAIESMQKALHDAGLHASDIGYINAHGTATPLNDAMESKAVNAVFGSHTPI
SSTKPFTGHTLGAAGIIEAAICWHILKYDLPLPRQINDNQKDETLADIKLVTDQRLEKPAIISNSFAFGGNNISLIFGYQ
S

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP [H]

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=263, Percent_Identity=39.9239543726236, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI223972627, Length=145, Percent_Identity=44.8275862068966, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI41872631, Length=264, Percent_Identity=29.9242424242424, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1787337, Length=260, Percent_Identity=36.9230769230769, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1788663, Length=262, Percent_Identity=32.4427480916031, Blast_Score=124, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI71983541, Length=409, Percent_Identity=31.0513447432763, Blast_Score=128, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI71983535, Length=259, Percent_Identity=32.8185328185328, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI212642053, Length=267, Percent_Identity=27.3408239700375, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17550940, Length=258, Percent_Identity=25.5813953488372, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6320904, Length=275, Percent_Identity=31.6363636363636, Blast_Score=109, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24644341, Length=265, Percent_Identity=36.6037735849057, Blast_Score=143, Evalue=2e-34,
Organism=Drosophila melanogaster, GI221330659, Length=265, Percent_Identity=27.5471698113208, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI19920632, Length=265, Percent_Identity=27.5471698113208, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 42664; Mature: 42664

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKSKMSDFPVYIHACGSHSALGKESNDIHQALNGNQGSSMMLEDGWLNDGKKTVVGKAE
CCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHCCCCCCEEEEECCCCCCCCEEEEECCC
GELPSIPAHLSLFDTRNNQLVLSALQQIEPQIKEAKAKYGSDRIAVIVGTSTSGISDGEA
CCCCCCCCEEEEEECCCCHHHHHHHHHHCHHHHHHHHHCCCCEEEEEEECCCCCCCCHHH
ALSEKLNSGIFPDDYHYRKQELGNPAEFVATYLELSGPTYAISTACSSSGRVFLSAKRLL
HHHHHHHCCCCCCCCHHHHHHCCCHHHHHHHHHHCCCCEEEEEECCCCCCEEEEHHHHHH
KSGFVDAVIVGGTDSLCKLTLNGFNSLEALSNEHCLPFSPNRKGINIGEASAYMLLSAEQ
HCCCCCEEEECCCCCEEEEEECCCCHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEECC
KDSNDPIALLGAGDSSDAHHISAPHPEGKGAIESMQKALHDAGLHASDIGYINAHGTATP
CCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEECCCCCCC
LNDAMESKAVNAVFGSHTPISSTKPFTGHTLGAAGIIEAAICWHILKYDLPLPRQINDNQ
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCC
KDETLADIKLVTDQRLEKPAIISNSFAFGGNNISLIFGYQS
CCHHHHHEEEEHHHHCCCCCEEECCEEECCCCEEEEEEECC
>Mature Secondary Structure
MDKSKMSDFPVYIHACGSHSALGKESNDIHQALNGNQGSSMMLEDGWLNDGKKTVVGKAE
CCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHCCCCCCEEEEECCCCCCCCEEEEECCC
GELPSIPAHLSLFDTRNNQLVLSALQQIEPQIKEAKAKYGSDRIAVIVGTSTSGISDGEA
CCCCCCCCEEEEEECCCCHHHHHHHHHHCHHHHHHHHHCCCCEEEEEEECCCCCCCCHHH
ALSEKLNSGIFPDDYHYRKQELGNPAEFVATYLELSGPTYAISTACSSSGRVFLSAKRLL
HHHHHHHCCCCCCCCHHHHHHCCCHHHHHHHHHHCCCCEEEEEECCCCCCEEEEHHHHHH
KSGFVDAVIVGGTDSLCKLTLNGFNSLEALSNEHCLPFSPNRKGINIGEASAYMLLSAEQ
HCCCCCEEEECCCCCEEEEEECCCCHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEECC
KDSNDPIALLGAGDSSDAHHISAPHPEGKGAIESMQKALHDAGLHASDIGYINAHGTATP
CCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEECCCCCCC
LNDAMESKAVNAVFGSHTPISSTKPFTGHTLGAAGIIEAAICWHILKYDLPLPRQINDNQ
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCC
KDETLADIKLVTDQRLEKPAIISNSFAFGGNNISLIFGYQS
CCHHHHHEEEEHHHHCCCCCEEECCEEECCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA