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The map label for this gene is tcpI [H]

Identifier: 209695135

GI number: 209695135

Start: 1740065

End: 1741708

Strand: Reverse

Name: tcpI [H]

Synonym: VSAL_I1636

Alternate gene names: 209695135

Gene position: 1741708-1740065 (Counterclockwise)

Preceding gene: 209695139

Following gene: 209695125

Centisome position: 52.38

GC content: 32.97

Gene sequence:

>1644_bases
ATGGATAGTCTTTCAAAATTAACAATTAGAAGCAGGCTTATTATTGGCTTTGGCATAACTTTATTTTTAATGTTGTTATT
AACTGTTTTAGGAATACAAAAAGTTAATACTATCGATCATACATTAACTGAAATGACGGATGTAAACTCAGTTAAACAGC
GTTATGCCATCAATTACCGTGGTAGTGTTCATGACCGTGCTATAGCGATTAGAGATATTGCCATAGCACGAACGCCACAA
GAGATATACAAACTAGAACAAGAAATTAATAAATTAAAAGAATTCTACCTTCAATCTGAAACTAAGATGAATGAAATGCA
CTCACAAGGTGTAGTATTTACAGAAAAAGAACAAAGTATTTTAGCTGAGATTAATAGAATTCAAAAGCAAACACTGCCTC
TTGTTGATCGTATTATTAACGATAAAAAATCAGACTCTGTAATGACAGATACCATCCTTGACTCTGCACGCCCTGCCTTT
ATTCAATGGTTGAAAGTAATTAATGAGTTTATTGAATATCAGGAAGAGCATAATCAGGTTTTAACTTTTGAAGCCAGAAA
TGTCGTCGGTGGTTTTCAACAGCTAATGTTATTACTTAGTGCTTTTGCTTTAACTATGTCTTTACTTATTGGTTTTATTA
TTGAACGCAGTTTTAGAATATCTTTAGGTGGTGAACCATGGGAATTATCTGAGATGATTAAAAAAATATCAGAGGGCAAT
TTATCTCAAGATTTTCATCATTCGTCGAACGCTGTAGGCATATATCATTCTTTAATTATTTTGAACAAAAAAGTCGGAGC
TGCAATTAGAAATAGTAGTGATATATCAACTCATGTAGCTACTTCATCTGAGCAATTAACTATTGTTATGCAAAATACGG
CAAGTAATGCTCAATATGAATTAGCACAAGTCGAAGAAATTTCACATGCAATCAGTGAGTTGTCGACAACTTCAAGAGAG
GTGACTTCTAATGCTGTTCACGCTGAAGAAGAAGTCAGTAAAGCAATTGATAGTGTATCCCAAGGAAATAAAACATTAGA
TGAATCGATTTTATTAACACAAAAAATTAATGAATCAGTACAACAAACAGCCAGTATGATTGCGGAGTTAAAAACTAATG
CAATGGATATTGGTGAAGTGACAGCTGTTATTAGTTCTATTTCTGATCAAACTAATTTATTAGCGTTAAATGCCGCGATT
GAAGCTGCTCGTGCTGGTGAATATGGCCGTGGTTTTGCTGTTGTAGCAGATGAAGTTCGTAACCTTGCTTCTAAAACTCA
AGAATCAACACAAAGTATTCAAGAAATTATTGCTCAATTGCAAGCTCAATCTGAAAGAGCAAACGATAATATGATAAGTA
ATGTAGAGCTTATCCAAGAATTAGTTGCTCTATCTGAAAACGTTAAATCATCTTTTGGTTATATTGAGAATTCAGTTCAA
TCAATTTCCAAAATGAATGCTTTGGTAGCAAGTACGTCTCAAGAACAATTCACTCTTACAGAAAGAATTGGACTTAATGT
TAGTAATACATTTGATTTAGTGAATCAGAATGTGGCGGCTATTAATCAAACGCAACAATCAGCTAAAGAATTGTCACAAT
TAGCTGTATCACAAAAGAAAGAATTAGAATTTTTCAAAGTGTAA

Upstream 100 bases:

>100_bases
ACACCTTTGTTTTTAGTGAGATTGTATATTAAATTTGTTAGTTATAGAGTAAGATAATCATCTTTCTATATAACATAGAT
GATTAAACGGAAAACAAATT

Downstream 100 bases:

>100_bases
TTAGCCGTATTATAAAAAAGCTCTTATAACTTTAGTTACAAGAGCTTTTATCCTAAATAGCATTAAATTTTTAATGATTT
AATGCTATTTAAAAGTTCAT

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: TCP pilus biosynthesis protein tcpI [H]

Number of amino acids: Translated: 547; Mature: 547

Protein sequence:

>547_residues
MDSLSKLTIRSRLIIGFGITLFLMLLLTVLGIQKVNTIDHTLTEMTDVNSVKQRYAINYRGSVHDRAIAIRDIAIARTPQ
EIYKLEQEINKLKEFYLQSETKMNEMHSQGVVFTEKEQSILAEINRIQKQTLPLVDRIINDKKSDSVMTDTILDSARPAF
IQWLKVINEFIEYQEEHNQVLTFEARNVVGGFQQLMLLLSAFALTMSLLIGFIIERSFRISLGGEPWELSEMIKKISEGN
LSQDFHHSSNAVGIYHSLIILNKKVGAAIRNSSDISTHVATSSEQLTIVMQNTASNAQYELAQVEEISHAISELSTTSRE
VTSNAVHAEEEVSKAIDSVSQGNKTLDESILLTQKINESVQQTASMIAELKTNAMDIGEVTAVISSISDQTNLLALNAAI
EAARAGEYGRGFAVVADEVRNLASKTQESTQSIQEIIAQLQAQSERANDNMISNVELIQELVALSENVKSSFGYIENSVQ
SISKMNALVASTSQEQFTLTERIGLNVSNTFDLVNQNVAAINQTQQSAKELSQLAVSQKKELEFFKV

Sequences:

>Translated_547_residues
MDSLSKLTIRSRLIIGFGITLFLMLLLTVLGIQKVNTIDHTLTEMTDVNSVKQRYAINYRGSVHDRAIAIRDIAIARTPQ
EIYKLEQEINKLKEFYLQSETKMNEMHSQGVVFTEKEQSILAEINRIQKQTLPLVDRIINDKKSDSVMTDTILDSARPAF
IQWLKVINEFIEYQEEHNQVLTFEARNVVGGFQQLMLLLSAFALTMSLLIGFIIERSFRISLGGEPWELSEMIKKISEGN
LSQDFHHSSNAVGIYHSLIILNKKVGAAIRNSSDISTHVATSSEQLTIVMQNTASNAQYELAQVEEISHAISELSTTSRE
VTSNAVHAEEEVSKAIDSVSQGNKTLDESILLTQKINESVQQTASMIAELKTNAMDIGEVTAVISSISDQTNLLALNAAI
EAARAGEYGRGFAVVADEVRNLASKTQESTQSIQEIIAQLQAQSERANDNMISNVELIQELVALSENVKSSFGYIENSVQ
SISKMNALVASTSQEQFTLTERIGLNVSNTFDLVNQNVAAINQTQQSAKELSQLAVSQKKELEFFKV
>Mature_547_residues
MDSLSKLTIRSRLIIGFGITLFLMLLLTVLGIQKVNTIDHTLTEMTDVNSVKQRYAINYRGSVHDRAIAIRDIAIARTPQ
EIYKLEQEINKLKEFYLQSETKMNEMHSQGVVFTEKEQSILAEINRIQKQTLPLVDRIINDKKSDSVMTDTILDSARPAF
IQWLKVINEFIEYQEEHNQVLTFEARNVVGGFQQLMLLLSAFALTMSLLIGFIIERSFRISLGGEPWELSEMIKKISEGN
LSQDFHHSSNAVGIYHSLIILNKKVGAAIRNSSDISTHVATSSEQLTIVMQNTASNAQYELAQVEEISHAISELSTTSRE
VTSNAVHAEEEVSKAIDSVSQGNKTLDESILLTQKINESVQQTASMIAELKTNAMDIGEVTAVISSISDQTNLLALNAAI
EAARAGEYGRGFAVVADEVRNLASKTQESTQSIQEIIAQLQAQSERANDNMISNVELIQELVALSENVKSSFGYIENSVQ
SISKMNALVASTSQEQFTLTERIGLNVSNTFDLVNQNVAAINQTQQSAKELSQLAVSQKKELEFFKV

Specific function: May function as an environmental regulator of TCP biogenesis. Negatively regulates the synthesis of the major pilin subunit of TCP (tcpA) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=397, Percent_Identity=25.4408060453401, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI2367378, Length=359, Percent_Identity=26.4623955431755, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1788195, Length=259, Percent_Identity=30.5019305019305, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI1788194, Length=164, Percent_Identity=35.3658536585366, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI1789453, Length=207, Percent_Identity=29.4685990338164, Blast_Score=81, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004089 [H]

Pfam domain/function: PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 60770; Mature: 60770

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSLSKLTIRSRLIIGFGITLFLMLLLTVLGIQKVNTIDHTLTEMTDVNSVKQRYAINYR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GSVHDRAIAIRDIAIARTPQEIYKLEQEINKLKEFYLQSETKMNEMHSQGVVFTEKEQSI
CCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECHHHHH
LAEINRIQKQTLPLVDRIINDKKSDSVMTDTILDSARPAFIQWLKVINEFIEYQEEHNQV
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCE
LTFEARNVVGGFQQLMLLLSAFALTMSLLIGFIIERSFRISLGGEPWELSEMIKKISEGN
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHCCC
LSQDFHHSSNAVGIYHSLIILNKKVGAAIRNSSDISTHVATSSEQLTIVMQNTASNAQYE
CCCHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHEECCCCEEEEEEECCCCCCHHH
LAQVEEISHAISELSTTSREVTSNAVHAEEEVSKAIDSVSQGNKTLDESILLTQKINESV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
QQTASMIAELKTNAMDIGEVTAVISSISDQTNLLALNAAIEAARAGEYGRGFAVVADEVR
HHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHEEEHHHHHHHHHCCCCCCCHHHHHHHHH
NLASKTQESTQSIQEIIAQLQAQSERANDNMISNVELIQELVALSENVKSSFGYIENSVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SISKMNALVASTSQEQFTLTERIGLNVSNTFDLVNQNVAAINQTQQSAKELSQLAVSQKK
HHHHHHHHHHCCCCHHEEHHHHHCCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHH
ELEFFKV
CCHHHCC
>Mature Secondary Structure
MDSLSKLTIRSRLIIGFGITLFLMLLLTVLGIQKVNTIDHTLTEMTDVNSVKQRYAINYR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GSVHDRAIAIRDIAIARTPQEIYKLEQEINKLKEFYLQSETKMNEMHSQGVVFTEKEQSI
CCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECHHHHH
LAEINRIQKQTLPLVDRIINDKKSDSVMTDTILDSARPAFIQWLKVINEFIEYQEEHNQV
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCE
LTFEARNVVGGFQQLMLLLSAFALTMSLLIGFIIERSFRISLGGEPWELSEMIKKISEGN
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHCCC
LSQDFHHSSNAVGIYHSLIILNKKVGAAIRNSSDISTHVATSSEQLTIVMQNTASNAQYE
CCCHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHEECCCCEEEEEEECCCCCCHHH
LAQVEEISHAISELSTTSREVTSNAVHAEEEVSKAIDSVSQGNKTLDESILLTQKINESV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
QQTASMIAELKTNAMDIGEVTAVISSISDQTNLLALNAAIEAARAGEYGRGFAVVADEVR
HHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHEEEHHHHHHHHHCCCCCCCHHHHHHHHH
NLASKTQESTQSIQEIIAQLQAQSERANDNMISNVELIQELVALSENVKSSFGYIENSVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SISKMNALVASTSQEQFTLTERIGLNVSNTFDLVNQNVAAINQTQQSAKELSQLAVSQKK
HHHHHHHHHHCCCCHHEEHHHHHCCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHH
ELEFFKV
CCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8005659 [H]