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The map label for this gene is corC [H]

Identifier: 209694556

GI number: 209694556

Start: 1097468

End: 1098343

Strand: Reverse

Name: corC [H]

Synonym: VSAL_I0993

Alternate gene names: 209694556

Gene position: 1098343-1097468 (Counterclockwise)

Preceding gene: 209694557

Following gene: 209694555

Centisome position: 33.03

GC content: 40.98

Gene sequence:

>876_bases
ATGAACGACGAAAATTCACAAAATACAGAAGGTCCGAGTAGAAAGTCCTTCTTAGGACGCCTTTCACAACTGTTCCAAGG
GGAACCTAAAGATCGCCAAGAGTTGGTGGATGTATTTAGAGACTCTGAGGAAAATGAAGTTATTGACCACGACACCCGAG
ACATGCTCGAAGGCGTCATGGAAATTTCTGAAATGAGAGTTCGAGACATTATGTTACCGCGCTCCCAGATGGTCACTGTA
GAGAAAACGCAAAACCTCGAATCACTGATAGCAACAATCATAGAAGCGTCACACTCACGCTACCCTGTGATCAGTGAAGA
CAAAGACCATGTTGAAGGAATACTCCTTGCGAAGGACTTATTAAGATACTTAGGTTCAGATTGTGAAGCCTTTGAGATTG
AACAAGTTATTCGACCTGCTGTTGTAGTACCAGAAAGCAAACGTGTTGATAAGCTTTTAAAAGAGTTTAGAGAAGAACGT
TACCACATGGCCATCGTTGTCGATGAGTTTGGTGGGGTTTCTGGTTTAGTTACTATCGAAGATATCCTTGAAGAAATTGT
TGGGGATATTGAAGATGAATTTGATGATGAAGAAGAGAAAGACATCCGTCAGTTAAGCAAACACACATTTGCTGTGAAAG
CATTAACTGAAATCGATGACTTTAACGACGCTTTCTTAACAAATTTTAGTGACGAAGAGATTGATACCGTTGGCGGCTTA
GTATTAACGACCTTTGGGCATTTGCCTGAAAGTGGTGAAACTATCGAAATATCTGGTTTTACGTTTAAAGTCACCGCTGC
CGATAACCGTCGCATCATCCAACTTCAAGTGACGATTCCTGAAAAAGAATCAGACAAAAAACACGAAGAAGAGTAA

Upstream 100 bases:

>100_bases
ATTTGAAGACCCATATCTCGCTGAGAAATAATTGTTGGAATAATCCAACAGTTACCTATGTGAGCTATCCACATTGATAG
CAACTACTTTTAAAGAAGCC

Downstream 100 bases:

>100_bases
CATTCTCAGCCGCTTATTAATAAGCGGCTGAACTTTATCTGGCTTCCAGAGACTAAATAGCTGTTATTTCATTATTTGTT
TGAGATCCTTCATGCCCTTT

Product: hemolysin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MNDENSQNTEGPSRKSFLGRLSQLFQGEPKDRQELVDVFRDSEENEVIDHDTRDMLEGVMEISEMRVRDIMLPRSQMVTV
EKTQNLESLIATIIEASHSRYPVISEDKDHVEGILLAKDLLRYLGSDCEAFEIEQVIRPAVVVPESKRVDKLLKEFREER
YHMAIVVDEFGGVSGLVTIEDILEEIVGDIEDEFDDEEEKDIRQLSKHTFAVKALTEIDDFNDAFLTNFSDEEIDTVGGL
VLTTFGHLPESGETIEISGFTFKVTAADNRRIIQLQVTIPEKESDKKHEEE

Sequences:

>Translated_291_residues
MNDENSQNTEGPSRKSFLGRLSQLFQGEPKDRQELVDVFRDSEENEVIDHDTRDMLEGVMEISEMRVRDIMLPRSQMVTV
EKTQNLESLIATIIEASHSRYPVISEDKDHVEGILLAKDLLRYLGSDCEAFEIEQVIRPAVVVPESKRVDKLLKEFREER
YHMAIVVDEFGGVSGLVTIEDILEEIVGDIEDEFDDEEEKDIRQLSKHTFAVKALTEIDDFNDAFLTNFSDEEIDTVGGL
VLTTFGHLPESGETIEISGFTFKVTAADNRRIIQLQVTIPEKESDKKHEEE
>Mature_291_residues
MNDENSQNTEGPSRKSFLGRLSQLFQGEPKDRQELVDVFRDSEENEVIDHDTRDMLEGVMEISEMRVRDIMLPRSQMVTV
EKTQNLESLIATIIEASHSRYPVISEDKDHVEGILLAKDLLRYLGSDCEAFEIEQVIRPAVVVPESKRVDKLLKEFREER
YHMAIVVDEFGGVSGLVTIEDILEEIVGDIEDEFDDEEEKDIRQLSKHTFAVKALTEIDDFNDAFLTNFSDEEIDTVGGL
VLTTFGHLPESGETIEISGFTFKVTAADNRRIIQLQVTIPEKESDKKHEEE

Specific function: Plays a role in the transport of magnesium and cobalt ions [H]

COG id: COG4535

COG function: function code P; Putative Mg2+ and Co2+ transporter CorC

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=206, Percent_Identity=34.4660194174757, Blast_Score=134, Evalue=9e-32,
Organism=Escherichia coli, GI1786879, Length=292, Percent_Identity=63.013698630137, Blast_Score=363, Evalue=1e-101,
Organism=Escherichia coli, GI145693175, Length=246, Percent_Identity=26.4227642276423, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1788119, Length=224, Percent_Identity=31.25, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1790664, Length=249, Percent_Identity=26.5060240963855, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI87082033, Length=273, Percent_Identity=23.4432234432234, Blast_Score=85, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC [H]

EC number: NA

Molecular weight: Translated: 33237; Mature: 33237

Theoretical pI: Translated: 4.14; Mature: 4.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDENSQNTEGPSRKSFLGRLSQLFQGEPKDRQELVDVFRDSEENEVIDHDTRDMLEGVM
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
EISEMRVRDIMLPRSQMVTVEKTQNLESLIATIIEASHSRYPVISEDKDHVEGILLAKDL
HHHHHHHHHHHCCHHHEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
LRYLGSDCEAFEIEQVIRPAVVVPESKRVDKLLKEFREERYHMAIVVDEFGGVSGLVTIE
HHHHCCCCCHHHHHHHHCCCEECCCHHHHHHHHHHHHHCCEEEEEEEECCCCCCCEEEHH
DILEEIVGDIEDEFDDEEEKDIRQLSKHTFAVKALTEIDDFNDAFLTNFSDEEIDTVGGL
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHH
VLTTFGHLPESGETIEISGFTFKVTAADNRRIIQLQVTIPEKESDKKHEEE
HHHHHCCCCCCCCEEEEECEEEEEEECCCCEEEEEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MNDENSQNTEGPSRKSFLGRLSQLFQGEPKDRQELVDVFRDSEENEVIDHDTRDMLEGVM
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
EISEMRVRDIMLPRSQMVTVEKTQNLESLIATIIEASHSRYPVISEDKDHVEGILLAKDL
HHHHHHHHHHHCCHHHEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
LRYLGSDCEAFEIEQVIRPAVVVPESKRVDKLLKEFREERYHMAIVVDEFGGVSGLVTIE
HHHHCCCCCHHHHHHHHCCCEECCCHHHHHHHHHHHHHCCEEEEEEEECCCCCCCEEEHH
DILEEIVGDIEDEFDDEEEKDIRQLSKHTFAVKALTEIDDFNDAFLTNFSDEEIDTVGGL
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHH
VLTTFGHLPESGETIEISGFTFKVTAADNRRIIQLQVTIPEKESDKKHEEE
HHHHHCCCCCCCCEEEEECEEEEEEECCCCEEEEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]