Click here to switch to the map view.

The map label for this gene is slyD [H]

Identifier: 209693908

GI number: 209693908

Start: 348699

End: 349289

Strand: Direct

Name: slyD [H]

Synonym: VSAL_I0302

Alternate gene names: 209693908

Gene position: 348699-349289 (Clockwise)

Preceding gene: 209693907

Following gene: 209693911

Centisome position: 10.49

GC content: 45.69

Gene sequence:

>591_bases
ATGAAAATTGAAAAGAATGTTGTAGTTAGCCTTGCTTACCAAGTTAAAACTGAAGAAGGCGTTGTTGTTGATCAATCAAC
AGCTGAAGCACCTCTTGATTACTTACACGGCCACGACAATCTGATTGTTGGTCTTGAAAAAGCACTTGAAGGCAAAGTTG
CAGGCGATAAGTTCAGCATCACTGTTGCTCCAGAAGAAGCGTACGGCGAGCACATGGATGAGATGATTCAACGTGTTCCT
GCTGATGTATTCCAAGGCGTTGAGCAAATTGAAGTTGGCATGCGTTTCCTTGCTGACACCGATCAAGGTCCAATTCCTGT
AGAAGTAACGGAAGTTGATGGCGACGAAGTTGTTGTTGATGGTAACCACATGCTTGCTGGTCAAACACTAGGCTTTGAAG
TTGAAGTGATTGCGGTTCGTGCTGCGACTGAAGAAGAAGCAACTCATGGTCATGTTCATCAAGAAGGTGGCTGTGGTCAC
GATCACGGACACGACCATGATCATGAAGGCGGTTGTTGTGGTGGCGAAGGCCATTCTCACGAGCACAAAGAAGATCATGA
GTGTTGTGGTAGCGGTAACTGCTCTAAGTAA

Upstream 100 bases:

>100_bases
ACACGCTCAAGATGATGTTATTGGTGTATTTAAACCTGAATAGCGTTATCTTTGTGGCAATAAATATCATCCTTTAATGC
GAAGTGCATCCGGAGTTAAA

Downstream 100 bases:

>100_bases
TCTTTTAAGAACAGAAACGAGGACGCTTCGCTTGAGAGTTTAGGGGCGAGGAAGAGCTTCGTACTGTAGAAATTAAAAAA
CCGTAGGTGCTGATGCATTT

Product: FKBP-type peptidyl-prolyl cis-trans isomerase SlyD

Products: NA

Alternate protein names: PPIase; Metallochaperone slyD [H]

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MKIEKNVVVSLAYQVKTEEGVVVDQSTAEAPLDYLHGHDNLIVGLEKALEGKVAGDKFSITVAPEEAYGEHMDEMIQRVP
ADVFQGVEQIEVGMRFLADTDQGPIPVEVTEVDGDEVVVDGNHMLAGQTLGFEVEVIAVRAATEEEATHGHVHQEGGCGH
DHGHDHDHEGGCCGGEGHSHEHKEDHECCGSGNCSK

Sequences:

>Translated_196_residues
MKIEKNVVVSLAYQVKTEEGVVVDQSTAEAPLDYLHGHDNLIVGLEKALEGKVAGDKFSITVAPEEAYGEHMDEMIQRVP
ADVFQGVEQIEVGMRFLADTDQGPIPVEVTEVDGDEVVVDGNHMLAGQTLGFEVEVIAVRAATEEEATHGHVHQEGGCGH
DHGHDHDHEGGCCGGEGHSHEHKEDHECCGSGNCSK
>Mature_196_residues
MKIEKNVVVSLAYQVKTEEGVVVDQSTAEAPLDYLHGHDNLIVGLEKALEGKVAGDKFSITVAPEEAYGEHMDEMIQRVP
ADVFQGVEQIEVGMRFLADTDQGPIPVEVTEVDGDEVVVDGNHMLAGQTLGFEVEVIAVRAATEEEATHGHVHQEGGCGH
DHGHDHDHEGGCCGGEGHSHEHKEDHECCGSGNCSK

Specific function: Also involved in hydrogenase metallocenter assembly, probably by participating in the nickel insertion step. This function in hydrogenase biosynthesis requires chaperone activity and the presence of the metal-binding domain, but not PPIase activity [H]

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1789748, Length=146, Percent_Identity=65.0684931506849, Blast_Score=199, Evalue=1e-52,
Organism=Escherichia coli, GI1786211, Length=146, Percent_Identity=30.8219178082192, Blast_Score=67, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 21052; Mature: 21052

Theoretical pI: Translated: 4.32; Mature: 4.32

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIEKNVVVSLAYQVKTEEGVVVDQSTAEAPLDYLHGHDNLIVGLEKALEGKVAGDKFSI
CCCCCCEEEEEEEEEECCCCEEEECCCCCCCHHHHCCCCCEEEEEHHHHCCCCCCCEEEE
TVAPEEAYGEHMDEMIQRVPADVFQGVEQIEVGMRFLADTDQGPIPVEVTEVDGDEVVVD
EECCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEEC
GNHMLAGQTLGFEVEVIAVRAATEEEATHGHVHQEGGCGHDHGHDHDHEGGCCGGEGHSH
CCEEEECCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
EHKEDHECCGSGNCSK
CCCCHHHHCCCCCCCC
>Mature Secondary Structure
MKIEKNVVVSLAYQVKTEEGVVVDQSTAEAPLDYLHGHDNLIVGLEKALEGKVAGDKFSI
CCCCCCEEEEEEEEEECCCCEEEECCCCCCCHHHHCCCCCEEEEEHHHHCCCCCCCEEEE
TVAPEEAYGEHMDEMIQRVPADVFQGVEQIEVGMRFLADTDQGPIPVEVTEVDGDEVVVD
EECCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEEC
GNHMLAGQTLGFEVEVIAVRAATEEEATHGHVHQEGGCGHDHGHDHDHEGGCCGGEGHSH
CCEEEECCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
EHKEDHECCGSGNCSK
CCCCHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]