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The map label for this gene is ddc [H]

Identifier: 209693756

GI number: 209693756

Start: 169900

End: 171447

Strand: Direct

Name: ddc [H]

Synonym: VSAL_I0134

Alternate gene names: 209693756

Gene position: 169900-171447 (Clockwise)

Preceding gene: 209693755

Following gene: 209693757

Centisome position: 5.11

GC content: 39.92

Gene sequence:

>1548_bases
ATGGATACTAAATATTTTGAAAAAAACGCCAATAACGATACTCTCTTTAACCAAAGTAGTCTCTTAAGTAATGTGGATTT
TTTTGATTCAAGTTCTTTAGATCATTATAAAGAAATCACAGAGTTAGGGCTCAACACGCTTATTAAAACAGTAAAAGAAA
CATCACACCCTAATTCTGGGATCTCGCCAGAAGAATTAAAGAACGCCTTCAAAAATATAGATTTAGATTCTCCTTTAATT
GATATTAATGATGTTGTAGATGAATTGGATGAGCTTTACCTTAAGCATGCTGTCTATTTCCATCATAAAGATTACTTAGC
GCATTTAAATTGCCCTGTATTATTAACCTCATTATTAGCTGAGCAAATTAGCTGTGCGATTAATACCGCGGTTGAAACCT
GGGATCAAAGTGCCGGTGGTACATTCATTGAACAGAAAGTAATAGATTGGCTTGCATACCGTATAGGTTATCTAAAGTCT
GCCGATGGTGTATTTACCACTGGAGGTACACAATCTAATCTAATGGCACTGTTACTGGCCAGAGAGCAATGCAGCACTAA
ACTTGATGACACCAAGAAAGCATCATTACCTACCAATACCAGTAAATTCCGTATTCTTTGTTCTGAATACAGCCATTATA
GTATTCAAAAAGCGGCATTCGTTTTAGGCTTAGGTCAAGAGGCGGTAATTAGTGTTCCTGCTAACGCTCAGCGACAAATG
GATCCGACTGCGCTTTCATCAACATTGGCATCACTGGTAGAGCAAGGATTAATTCCAATGGCGGTGGTTGCTACCGCTGG
CACCACCGATTTTGGTTCTATCGATCCTATCGAAGAGATAGCTTCTCTTTGTCAGCAATATCAATGTTGGTTGCATGTAG
ACGCGGCATACGGTGGCGTATTACTGATTTCGAATAAATTTCCTCACTTATTGAAAAGTATTGAACAAGCCGATTCTGTT
AGCATCGATTTTCATAAATCATTTTTCCAACCTTTATGCTGCTCAGCCCTTATGGTGAGTAATGGTCAATCTCTTTCTCA
TCTTACCTATCATGCCGATTACCTAAACCCAAAACACCAAGCCGATAATGGTATTCCTGACCTTGCCAACAAAAGTCTTC
AAACATCACGACGATTCGACGCTTTAAAGATTTGGCTTACTTTACGAGCTTGCGGGCCAGAAGCCATCGGTAAGTTATTT
GATGACTTAATCCTTAATACTCAAGAAGTCTATCAACGCAGTCAGCACCTAACCGATATTAAGTTTGTTCAAGAGCCACA
ACTGACCACATTGGTATTTAGATTCGTCGACCAACGCCTTACCCCGACAGAACAGGACACCTGCAACAGGGCAATTAGAG
AGGCACTTTCTAAATCAAGAAGAGCGTTAATCGCAGCAACCGTGGTTAAAGGTCGTCAATATCTCAAAATAACGATGTTA
AACCCTCAAACCCCCGTGAACAGCATCGTTGCCGTATTTGAAGCCATTAATACGTGTGGTCATTCAATCACCGAGCAACT
GCTTACCAATGTAAAACAAAGCGCCTAA

Upstream 100 bases:

>100_bases
CATGATAGATTCCATACACTCTCAAAAACAAAGATAAATAATACATCTCAGTTAATTACATGGGATTTCATTCAACATTG
ATAAATGCACAGAGAAAAAT

Downstream 100 bases:

>100_bases
TAAAAAAGGATATCCAGTGAATAAAAATATATACGATATTTTAGGTGTCGGTATTGGTCCATTTAATCTTAGCCTTGCCG
CCCTTTCTTCCTCTGTTCCT

Product: L-2,4-diaminobutyrate decarboxylase

Products: NA

Alternate protein names: DABA decarboxylase; DABA-DC [H]

Number of amino acids: Translated: 515; Mature: 515

Protein sequence:

>515_residues
MDTKYFEKNANNDTLFNQSSLLSNVDFFDSSSLDHYKEITELGLNTLIKTVKETSHPNSGISPEELKNAFKNIDLDSPLI
DINDVVDELDELYLKHAVYFHHKDYLAHLNCPVLLTSLLAEQISCAINTAVETWDQSAGGTFIEQKVIDWLAYRIGYLKS
ADGVFTTGGTQSNLMALLLAREQCSTKLDDTKKASLPTNTSKFRILCSEYSHYSIQKAAFVLGLGQEAVISVPANAQRQM
DPTALSSTLASLVEQGLIPMAVVATAGTTDFGSIDPIEEIASLCQQYQCWLHVDAAYGGVLLISNKFPHLLKSIEQADSV
SIDFHKSFFQPLCCSALMVSNGQSLSHLTYHADYLNPKHQADNGIPDLANKSLQTSRRFDALKIWLTLRACGPEAIGKLF
DDLILNTQEVYQRSQHLTDIKFVQEPQLTTLVFRFVDQRLTPTEQDTCNRAIREALSKSRRALIAATVVKGRQYLKITML
NPQTPVNSIVAVFEAINTCGHSITEQLLTNVKQSA

Sequences:

>Translated_515_residues
MDTKYFEKNANNDTLFNQSSLLSNVDFFDSSSLDHYKEITELGLNTLIKTVKETSHPNSGISPEELKNAFKNIDLDSPLI
DINDVVDELDELYLKHAVYFHHKDYLAHLNCPVLLTSLLAEQISCAINTAVETWDQSAGGTFIEQKVIDWLAYRIGYLKS
ADGVFTTGGTQSNLMALLLAREQCSTKLDDTKKASLPTNTSKFRILCSEYSHYSIQKAAFVLGLGQEAVISVPANAQRQM
DPTALSSTLASLVEQGLIPMAVVATAGTTDFGSIDPIEEIASLCQQYQCWLHVDAAYGGVLLISNKFPHLLKSIEQADSV
SIDFHKSFFQPLCCSALMVSNGQSLSHLTYHADYLNPKHQADNGIPDLANKSLQTSRRFDALKIWLTLRACGPEAIGKLF
DDLILNTQEVYQRSQHLTDIKFVQEPQLTTLVFRFVDQRLTPTEQDTCNRAIREALSKSRRALIAATVVKGRQYLKITML
NPQTPVNSIVAVFEAINTCGHSITEQLLTNVKQSA
>Mature_515_residues
MDTKYFEKNANNDTLFNQSSLLSNVDFFDSSSLDHYKEITELGLNTLIKTVKETSHPNSGISPEELKNAFKNIDLDSPLI
DINDVVDELDELYLKHAVYFHHKDYLAHLNCPVLLTSLLAEQISCAINTAVETWDQSAGGTFIEQKVIDWLAYRIGYLKS
ADGVFTTGGTQSNLMALLLAREQCSTKLDDTKKASLPTNTSKFRILCSEYSHYSIQKAAFVLGLGQEAVISVPANAQRQM
DPTALSSTLASLVEQGLIPMAVVATAGTTDFGSIDPIEEIASLCQQYQCWLHVDAAYGGVLLISNKFPHLLKSIEQADSV
SIDFHKSFFQPLCCSALMVSNGQSLSHLTYHADYLNPKHQADNGIPDLANKSLQTSRRFDALKIWLTLRACGPEAIGKLF
DDLILNTQEVYQRSQHLTDIKFVQEPQLTTLVFRFVDQRLTPTEQDTCNRAIREALSKSRRALIAATVVKGRQYLKITML
NPQTPVNSIVAVFEAINTCGHSITEQLLTNVKQSA

Specific function: Unknown

COG id: COG0076

COG function: function code E; Glutamate decarboxylase and related PLP-dependent proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the group II decarboxylase family [H]

Homologues:

Organism=Homo sapiens, GI58331246, Length=489, Percent_Identity=28.0163599182004, Blast_Score=187, Evalue=2e-47,
Organism=Homo sapiens, GI197276620, Length=407, Percent_Identity=30.2211302211302, Blast_Score=187, Evalue=2e-47,
Organism=Homo sapiens, GI4503875, Length=407, Percent_Identity=30.2211302211302, Blast_Score=187, Evalue=2e-47,
Organism=Homo sapiens, GI197383062, Length=455, Percent_Identity=28.3516483516484, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI194294551, Length=425, Percent_Identity=30.3529411764706, Blast_Score=182, Evalue=6e-46,
Organism=Homo sapiens, GI4503281, Length=329, Percent_Identity=28.2674772036474, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI132814448, Length=329, Percent_Identity=28.2674772036474, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI92110055, Length=351, Percent_Identity=25.6410256410256, Blast_Score=118, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17555682, Length=396, Percent_Identity=28.2828282828283, Blast_Score=169, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI71993062, Length=396, Percent_Identity=28.2828282828283, Blast_Score=168, Evalue=5e-42,
Organism=Caenorhabditis elegans, GI71993058, Length=359, Percent_Identity=30.3621169916435, Blast_Score=167, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI71981211, Length=468, Percent_Identity=21.7948717948718, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI71981217, Length=477, Percent_Identity=21.1740041928721, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17534819, Length=353, Percent_Identity=25.4957507082153, Blast_Score=112, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI17534817, Length=353, Percent_Identity=25.7790368271955, Blast_Score=111, Evalue=8e-25,
Organism=Caenorhabditis elegans, GI17551992, Length=454, Percent_Identity=22.2466960352423, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI133931025, Length=327, Percent_Identity=26.2996941896024, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24657193, Length=462, Percent_Identity=29.004329004329, Blast_Score=170, Evalue=3e-42,
Organism=Drosophila melanogaster, GI24657185, Length=462, Percent_Identity=29.004329004329, Blast_Score=170, Evalue=3e-42,
Organism=Drosophila melanogaster, GI24657188, Length=462, Percent_Identity=29.004329004329, Blast_Score=170, Evalue=3e-42,
Organism=Drosophila melanogaster, GI17136594, Length=450, Percent_Identity=28.8888888888889, Blast_Score=165, Evalue=9e-41,
Organism=Drosophila melanogaster, GI21356415, Length=403, Percent_Identity=28.5359801488834, Blast_Score=146, Evalue=4e-35,
Organism=Drosophila melanogaster, GI24652373, Length=419, Percent_Identity=26.7303102625298, Blast_Score=135, Evalue=5e-32,
Organism=Drosophila melanogaster, GI24585139, Length=323, Percent_Identity=28.1733746130031, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI221476190, Length=323, Percent_Identity=28.1733746130031, Blast_Score=127, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24585143, Length=323, Percent_Identity=28.1733746130031, Blast_Score=127, Evalue=3e-29,
Organism=Drosophila melanogaster, GI17136190, Length=397, Percent_Identity=24.6851385390428, Blast_Score=126, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24585135, Length=381, Percent_Identity=25.1968503937008, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24586044, Length=359, Percent_Identity=28.133704735376, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI28573972, Length=322, Percent_Identity=27.3291925465839, Blast_Score=109, Evalue=4e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002129
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR021115 [H]

Pfam domain/function: PF00282 Pyridoxal_deC [H]

EC number: =4.1.1.86 [H]

Molecular weight: Translated: 57163; Mature: 57163

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTKYFEKNANNDTLFNQSSLLSNVDFFDSSSLDHYKEITELGLNTLIKTVKETSHPNSG
CCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
ISPEELKNAFKNIDLDSPLIDINDVVDELDELYLKHAVYFHHKDYLAHLNCPVLLTSLLA
CCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
EQISCAINTAVETWDQSAGGTFIEQKVIDWLAYRIGYLKSADGVFTTGGTQSNLMALLLA
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHH
REQCSTKLDDTKKASLPTNTSKFRILCSEYSHYSIQKAAFVLGLGQEAVISVPANAQRQM
HHHHCCCCCCCCCCCCCCCCCHHEEEEHHCCCHHHHHHHHHHCCCCHHEEECCCCCCCCC
DPTALSSTLASLVEQGLIPMAVVATAGTTDFGSIDPIEEIASLCQQYQCWLHVDAAYGGV
CHHHHHHHHHHHHHCCCCCCHHHEECCCCCCCCCCCHHHHHHHHHHHHHHEEEECCCCCE
LLISNKFPHLLKSIEQADSVSIDFHKSFFQPLCCSALMVSNGQSLSHLTYHADYLNPKHQ
EEECCCCHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHCCCCCHHHHEEEHHHCCCHHC
ADNGIPDLANKSLQTSRRFDALKIWLTLRACGPEAIGKLFDDLILNTQEVYQRSQHLTDI
CCCCCCHHHHHHHHHHHHHHHEEEEHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHCCCHH
KFVQEPQLTTLVFRFVDQRLTPTEQDTCNRAIREALSKSRRALIAATVVKGRQYLKITML
HHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEE
NPQTPVNSIVAVFEAINTCGHSITEQLLTNVKQSA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDTKYFEKNANNDTLFNQSSLLSNVDFFDSSSLDHYKEITELGLNTLIKTVKETSHPNSG
CCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
ISPEELKNAFKNIDLDSPLIDINDVVDELDELYLKHAVYFHHKDYLAHLNCPVLLTSLLA
CCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
EQISCAINTAVETWDQSAGGTFIEQKVIDWLAYRIGYLKSADGVFTTGGTQSNLMALLLA
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHH
REQCSTKLDDTKKASLPTNTSKFRILCSEYSHYSIQKAAFVLGLGQEAVISVPANAQRQM
HHHHCCCCCCCCCCCCCCCCCHHEEEEHHCCCHHHHHHHHHHCCCCHHEEECCCCCCCCC
DPTALSSTLASLVEQGLIPMAVVATAGTTDFGSIDPIEEIASLCQQYQCWLHVDAAYGGV
CHHHHHHHHHHHHHCCCCCCHHHEECCCCCCCCCCCHHHHHHHHHHHHHHEEEECCCCCE
LLISNKFPHLLKSIEQADSVSIDFHKSFFQPLCCSALMVSNGQSLSHLTYHADYLNPKHQ
EEECCCCHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHCCCCCHHHHEEEHHHCCCHHC
ADNGIPDLANKSLQTSRRFDALKIWLTLRACGPEAIGKLFDDLILNTQEVYQRSQHLTDI
CCCCCCHHHHHHHHHHHHHHHEEEEHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHCCCHH
KFVQEPQLTTLVFRFVDQRLTPTEQDTCNRAIREALSKSRRALIAATVVKGRQYLKITML
HHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEE
NPQTPVNSIVAVFEAINTCGHSITEQLLTNVKQSA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800; 9514614 [H]