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The map label for this gene is glyS [H]

Identifier: 203284284

GI number: 203284284

Start: 393792

End: 395129

Strand: Reverse

Name: glyS [H]

Synonym: BDU_366

Alternate gene names: 203284284

Gene position: 395129-393792 (Counterclockwise)

Preceding gene: 203284285

Following gene: 203284283

Centisome position: 42.41

GC content: 32.51

Gene sequence:

>1338_bases
ATGTTTGATATGGCTAAAATAGAAGATATTATTTCACTTGCTAAGAGGCGAGGTTTTGTATTTCAATCCTCAGAAGTTTA
TGGGGGTTTGTCGGGTGTATGGGATTATGGGCCTTTAGGTGTTGAGATTAAGAAGAATATACAGGAAGAGTGGTGGAAAA
GTATGGTTTACTTTCATGAAAATGTTGTGGGATTAGATAGTGCTATTTTGATGAGGCCTGAAGTTTGGAAAGCTTCTGGA
CATGTTGATAGTTTTTTGGAATTATTAGTTGATTGTAGAAATTGTAAGAATAGATTTAGGACAGATTTTATTGATTTATC
TAAGGGGTGTCCTAATTGTGGTTCTATAGGAACTTTTACAACTCCTAGAAGTTTTAATTTGATGTTTAAGACTAATATTG
GGGCTGTTGAGGATAGTTCTAGTGAGATTTATTTAAGACCAGAGACTGCGCAGGGCATTTTTGTTAATTTTCGTAATGTA
TTGGATACTACAAGACTTAAGGTTCCATTTGGAATAGCACAAGTTGGTAAGGCTTTTAGGAATGAGATAATAGCAAAGAA
TTTTATATTTAGAGTTTGTGAGTTTGAACAAATGGAAATGCAGTTTTTTGTACATCCGAGTCAGATGGATGATTGGTATT
GTTATTGGCGAGAGAAAAGAATGAACTTTTTTATTGAAACTCTTGGAATCAAAGCTGATAATCTTAGATTTCAAAAACAC
AATGATGATGAGCTTGCTCATTATGCAAAAGCTGCAGTTGATATTGAATATAATTTTCCATTTGGTTTTCAAGAAATTGA
GGGAATTCATAATAGAGGTAATTATGATTTAAATCAACATGCTAAATTTTGTGGTAAATCTAAGTTGTTTGAATATCATG
ATTTGATAACAGGTGATAAGTATATTCCTTATGTAATTGAAACTTCTCTTGGACTTACAAGAAGTGTACTAATGACTCTT
TGTGATGCTTATGCTTGTGAGGAACTTGAGGGAGGGGATAAGCGAATAGTGTTACATTTACATCCTAAGATTGCTCCTTA
TAAGGTTGCAATACTTCCTCTTGTAAAGAAAGATGGATTACCCGAACTTGCTAGAAAAGTGTTTATGCAATTTAGCGATG
ATTTTTATATGTTTTATGATGAGAATGGTACGATAGGTAAGCGTTATAGACGTCAAGATGAAATTGGTACACCTTATTGT
GTAACAATAGATTATGATACGATTGAAAATAGGACAATAACTTTAAGAGATAGAGATACTATGACTCAAACAAGAATTTC
TATTGATGATTTGTATTCATATGTTAAAACGGGAATTCTAAATTACAAGGGAGTTTAA

Upstream 100 bases:

>100_bases
TTGATTCTTTGCAATTACTTGGTAAAGTTACGGTCTTTGATAGAATAAATAAAGCACAGGATTTTTTAAAAAAGTATGAA
TTATAGATTAAGTTTTTAGG

Downstream 100 bases:

>100_bases
ATAAATGAATTTATCCCTAAAGGTTTTAGATAAGAGAGGATTTTTAAAACAGTGTACTAATTTGGAAGAGTTAAGTACAT
TGATGGATAGAGAAAAAATA

Product: glycyl-tRNA synthetase

Products: NA

Alternate protein names: Glycine--tRNA ligase; GlyRS [H]

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MFDMAKIEDIISLAKRRGFVFQSSEVYGGLSGVWDYGPLGVEIKKNIQEEWWKSMVYFHENVVGLDSAILMRPEVWKASG
HVDSFLELLVDCRNCKNRFRTDFIDLSKGCPNCGSIGTFTTPRSFNLMFKTNIGAVEDSSSEIYLRPETAQGIFVNFRNV
LDTTRLKVPFGIAQVGKAFRNEIIAKNFIFRVCEFEQMEMQFFVHPSQMDDWYCYWREKRMNFFIETLGIKADNLRFQKH
NDDELAHYAKAAVDIEYNFPFGFQEIEGIHNRGNYDLNQHAKFCGKSKLFEYHDLITGDKYIPYVIETSLGLTRSVLMTL
CDAYACEELEGGDKRIVLHLHPKIAPYKVAILPLVKKDGLPELARKVFMQFSDDFYMFYDENGTIGKRYRRQDEIGTPYC
VTIDYDTIENRTITLRDRDTMTQTRISIDDLYSYVKTGILNYKGV

Sequences:

>Translated_445_residues
MFDMAKIEDIISLAKRRGFVFQSSEVYGGLSGVWDYGPLGVEIKKNIQEEWWKSMVYFHENVVGLDSAILMRPEVWKASG
HVDSFLELLVDCRNCKNRFRTDFIDLSKGCPNCGSIGTFTTPRSFNLMFKTNIGAVEDSSSEIYLRPETAQGIFVNFRNV
LDTTRLKVPFGIAQVGKAFRNEIIAKNFIFRVCEFEQMEMQFFVHPSQMDDWYCYWREKRMNFFIETLGIKADNLRFQKH
NDDELAHYAKAAVDIEYNFPFGFQEIEGIHNRGNYDLNQHAKFCGKSKLFEYHDLITGDKYIPYVIETSLGLTRSVLMTL
CDAYACEELEGGDKRIVLHLHPKIAPYKVAILPLVKKDGLPELARKVFMQFSDDFYMFYDENGTIGKRYRRQDEIGTPYC
VTIDYDTIENRTITLRDRDTMTQTRISIDDLYSYVKTGILNYKGV
>Mature_445_residues
MFDMAKIEDIISLAKRRGFVFQSSEVYGGLSGVWDYGPLGVEIKKNIQEEWWKSMVYFHENVVGLDSAILMRPEVWKASG
HVDSFLELLVDCRNCKNRFRTDFIDLSKGCPNCGSIGTFTTPRSFNLMFKTNIGAVEDSSSEIYLRPETAQGIFVNFRNV
LDTTRLKVPFGIAQVGKAFRNEIIAKNFIFRVCEFEQMEMQFFVHPSQMDDWYCYWREKRMNFFIETLGIKADNLRFQKH
NDDELAHYAKAAVDIEYNFPFGFQEIEGIHNRGNYDLNQHAKFCGKSKLFEYHDLITGDKYIPYVIETSLGLTRSVLMTL
CDAYACEELEGGDKRIVLHLHPKIAPYKVAILPLVKKDGLPELARKVFMQFSDDFYMFYDENGTIGKRYRRQDEIGTPYC
VTIDYDTIENRTITLRDRDTMTQTRISIDDLYSYVKTGILNYKGV

Specific function: Catalyzes the attachment of glycine to tRNA(Gly) [H]

COG id: COG0423

COG function: function code J; Glycyl-tRNA synthetase (class II)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI116805340, Length=366, Percent_Identity=31.9672131147541, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI70887790, Length=464, Percent_Identity=24.5689655172414, Blast_Score=106, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI32564541, Length=383, Percent_Identity=31.0704960835509, Blast_Score=156, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17554996, Length=380, Percent_Identity=30.7894736842105, Blast_Score=156, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6325338, Length=385, Percent_Identity=28.8311688311688, Blast_Score=144, Evalue=4e-35,
Organism=Saccharomyces cerevisiae, GI6319597, Length=216, Percent_Identity=33.3333333333333, Blast_Score=106, Evalue=1e-23,
Organism=Drosophila melanogaster, GI21357965, Length=365, Percent_Identity=32.0547945205479, Blast_Score=164, Evalue=9e-41,
Organism=Drosophila melanogaster, GI24664462, Length=365, Percent_Identity=32.0547945205479, Blast_Score=164, Evalue=9e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002314
- InterPro:   IPR006195
- InterPro:   IPR004154
- InterPro:   IPR022961
- InterPro:   IPR002315 [H]

Pfam domain/function: PF03129 HGTP_anticodon; PF00587 tRNA-synt_2b [H]

EC number: =6.1.1.14 [H]

Molecular weight: Translated: 51698; Mature: 51698

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDMAKIEDIISLAKRRGFVFQSSEVYGGLSGVWDYGPLGVEIKKNIQEEWWKSMVYFHE
CCCHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
NVVGLDSAILMRPEVWKASGHVDSFLELLVDCRNCKNRFRTDFIDLSKGCPNCGSIGTFT
CHHCCCHHEEECCCHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCC
TPRSFNLMFKTNIGAVEDSSSEIYLRPETAQGIFVNFRNVLDTTRLKVPFGIAQVGKAFR
CCCCEEEEEEECCCCEECCCCEEEEECCCCCEEEEEHHHHHHHHHEECCCCHHHHHHHHH
NEIIAKNFIFRVCEFEQMEMQFFVHPSQMDDWYCYWREKRMNFFIETLGIKADNLRFQKH
HHHHHHHHHHHHHHHHCEEEEEEECCCCCCCEEEEEHHHHHHEEHHHHCCCCCCEEEECC
NDDELAHYAKAAVDIEYNFPFGFQEIEGIHNRGNYDLNQHAKFCGKSKLFEYHDLITGDK
CCHHHHHHHHEEEEEEECCCCCHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHCCCCC
YIPYVIETSLGLTRSVLMTLCDAYACEELEGGDKRIVLHLHPKIAPYKVAILPLVKKDGL
CCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEEEECCCCCC
PELARKVFMQFSDDFYMFYDENGTIGKRYRRQDEIGTPYCVTIDYDTIENRTITLRDRDT
HHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEECCCC
MTQTRISIDDLYSYVKTGILNYKGV
HHHHHCCHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MFDMAKIEDIISLAKRRGFVFQSSEVYGGLSGVWDYGPLGVEIKKNIQEEWWKSMVYFHE
CCCHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
NVVGLDSAILMRPEVWKASGHVDSFLELLVDCRNCKNRFRTDFIDLSKGCPNCGSIGTFT
CHHCCCHHEEECCCHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCC
TPRSFNLMFKTNIGAVEDSSSEIYLRPETAQGIFVNFRNVLDTTRLKVPFGIAQVGKAFR
CCCCEEEEEEECCCCEECCCCEEEEECCCCCEEEEEHHHHHHHHHEECCCCHHHHHHHHH
NEIIAKNFIFRVCEFEQMEMQFFVHPSQMDDWYCYWREKRMNFFIETLGIKADNLRFQKH
HHHHHHHHHHHHHHHHCEEEEEEECCCCCCCEEEEEHHHHHHEEHHHHCCCCCCEEEECC
NDDELAHYAKAAVDIEYNFPFGFQEIEGIHNRGNYDLNQHAKFCGKSKLFEYHDLITGDK
CCHHHHHHHHEEEEEEECCCCCHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHCCCCC
YIPYVIETSLGLTRSVLMTLCDAYACEELEGGDKRIVLHLHPKIAPYKVAILPLVKKDGL
CCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEEEECCCCCC
PELARKVFMQFSDDFYMFYDENGTIGKRYRRQDEIGTPYCVTIDYDTIENRTITLRDRDT
HHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEECCCC
MTQTRISIDDLYSYVKTGILNYKGV
HHHHHCCHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA