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The map label for this gene is clpA [H]

Identifier: 203284282

GI number: 203284282

Start: 390268

End: 392577

Strand: Reverse

Name: clpA [H]

Synonym: BDU_364

Alternate gene names: 203284282

Gene position: 392577-390268 (Counterclockwise)

Preceding gene: 203284283

Following gene: 203284281

Centisome position: 42.14

GC content: 26.02

Gene sequence:

>2310_bases
TTGTTTTATAATTGGTGTTTCATGTATAACAGAAGAGCTTTAAATCATTTGTTTTTTAAATCGTTTCTGTTTTTTGTGGA
ACGTAAACATCTTTTTTTTACCGAAGAACATATCTTTTATAGTTTAATTAGTGATGATGAAATTAGAGAATTGCTTAGTT
TATGTGCACTTGATTTTTATAGTTTTAATAAAATTTTAGAAGAATTTTTTACAAAACTTCCTATAAGAAATGCTGATTTT
TATGATTATTTTTTTAAAATTAATGATTTATATCAAGAAATAATCGATACTATTTTTTATTATAAAAAACCTTATGTATT
ACAAGAGAAAGATTTGTTATGGGTATTAATTAGGAAAAGAAAAAATACAATTTTAGATGCTTTATTAAAATCGGGTTTTA
GTTTAGATATATTTGACAAAATAATGGAGATTTATGACTATTTAGGTTCGAATTTAGATTTAGGTTTTCTTAAAAATGAA
AAATTGCTTACAAATGATCTTTTTAATAAAGGGATAGATAAATATGGAGGTTTAAATATTTTTGAGGAAGATTATTTTAA
ATTAGAACAAGATGATGATTCATTGGATGAGAACAATTTGGTTGATGATTTCTTAGTTAATGTTATTGATAATTTGGATC
CCAATTTAGCTACAAATCCTTTGATTGGTCGCAAAAAAGAATTATATACATTAATTCAAATAATGCTTCGTAAACATAAA
AGTAATCCAATTGTATTTGGAGAGCCTGGGGTTGGAAAGACAATATTGCTTCAAGGACTTGCTTATATTATAAGAGAAGG
TCAGGTGCCTCATGAATTGATTGATTGTGAAGTTTATTCTCTTGATATTGGAAGACTTATATCTGGGACTAGGTATAGGG
GAGATCTTGAAAATCGGGTTAACAAACTCTTAGATTTTTTGCATTTTAAAAAAAAAGTAATTCTTTTTATAGATGAGATT
CATATGATAGTTGGAGCTGGTGCTACATCTTTTAGTAACATAGATGTTTCAAATTTATTAAAACCTATATTAACTTTGGG
TAAAATAAAGTTTATTGGGGCTACTACCAAAAATGAATATAAAAAATTTTTTTTGAAAGACAAAGCTTTACTAAGAAGAT
TTCATGGTGTTGAACTTAAAGAACCAAGTTTAGAGGATACTTATCATATTTTGAAAGGGGCTAAGGAACAATATGAAAAA
CATCATCATGTTGAGTATACAGATGAAGCTATATGGGTTGCAATTACTATGTCTAAATACATAAAAGATAGAGCTTTGCC
CGATAAAGCTTTTGATCTATTAGATGGTCTTGGCTCTAAATTTAAACTTGAGGGTAATAAAAAAGTTATAACAGGTGATG
ATGTCAGAGATTTTGTTAAGTATATGGTTGGAACCAGTATTTTTAATTTTGATGATTATGATCAAGATTTACTAATGAAT
TTGGAACATAAGATAAGAACAAGTATGATAATTGATGAGAGTATTTTATCCGAATTACTTTTGCATATTAAGCTTTTAAG
AATTAAATTTTTCTTTAAAAATAGTACTCTTGGTATTTTCATTTTAATTGGATCTTCTGATGTAGATAAGAATAAACTTG
CGTGTGTTTTATCAGAAGAACTTAATATGCCTAAACTTACTTTGGGAATGAGTGAATATTGTGATTTTGATGGTATTAAT
CGATTGATAGGACCAGTATATGGTTCTGAAGCTTATGATGAACCTACTAAATTCTTTAGATTTTTAAATGAGTCTTTAAA
TTCAATTATTGTTTTGTCAGATTTTGATAAGTCTTCTAAGAGAGTTATAGATTTTTTTTTTGAAGGATTTAATACAGGTA
GACTTTTTGATAATTTTGGTAGAAGTGTCAGTTTGTCAGGTAGCATTATAATTATAGATATTAATATAGAATATAGAGAA
CTTGATGGTATTGGATTTAAAAATGAAACTGTTGATATCAGAAGTTTATTAGAAAAACGTTTTTCTAATAAATTTCTAGA
CTTAGTAGATCATGTTTTTTTCTTTAGACCTGTAAGTAAGAGTGATTTTAAAAGGGTGATTATTGAAGAGGTGAATAATT
TTGTTAAAATACTAAAAAATGAAAAAATAGATCTTTTTTTTGAAGAGGCTGTTATTGGTTATTTTCAAAAACATATTTAT
GAGAATGGGCTTGGAATTAGGGGTATTCGTAAAATTGTGATTAAAGAAATTGGAAGTTTGTTGATTGATGATTTGATTTT
GAAAAAATTTAAAGAAAATGATAAGATTAGAATTTTTCTAGACGATACGATTAAATATGAGTTATTATAA

Upstream 100 bases:

>100_bases
GATAAAGTAAGGGTAGGAGATCAAAATTATTGCCTTTGTAAGGACAATTTTATCAATGGTGAAATTGAACTTAAAATAGG
CAAGAAAAAGATTTTGAGAA

Downstream 100 bases:

>100_bases
TTTTATGGTTATAAGGAGGTATATATGAAAATATCTATTGTGGGAGCAGGGGCTTGGGGTACTGCTGTTGCTAAAGTTTT
GGCAGATAAGTTTAAGGATC

Product: ATP-dependent Clp protease, subunit A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 769; Mature: 769

Protein sequence:

>769_residues
MFYNWCFMYNRRALNHLFFKSFLFFVERKHLFFTEEHIFYSLISDDEIRELLSLCALDFYSFNKILEEFFTKLPIRNADF
YDYFFKINDLYQEIIDTIFYYKKPYVLQEKDLLWVLIRKRKNTILDALLKSGFSLDIFDKIMEIYDYLGSNLDLGFLKNE
KLLTNDLFNKGIDKYGGLNIFEEDYFKLEQDDDSLDENNLVDDFLVNVIDNLDPNLATNPLIGRKKELYTLIQIMLRKHK
SNPIVFGEPGVGKTILLQGLAYIIREGQVPHELIDCEVYSLDIGRLISGTRYRGDLENRVNKLLDFLHFKKKVILFIDEI
HMIVGAGATSFSNIDVSNLLKPILTLGKIKFIGATTKNEYKKFFLKDKALLRRFHGVELKEPSLEDTYHILKGAKEQYEK
HHHVEYTDEAIWVAITMSKYIKDRALPDKAFDLLDGLGSKFKLEGNKKVITGDDVRDFVKYMVGTSIFNFDDYDQDLLMN
LEHKIRTSMIIDESILSELLLHIKLLRIKFFFKNSTLGIFILIGSSDVDKNKLACVLSEELNMPKLTLGMSEYCDFDGIN
RLIGPVYGSEAYDEPTKFFRFLNESLNSIIVLSDFDKSSKRVIDFFFEGFNTGRLFDNFGRSVSLSGSIIIIDINIEYRE
LDGIGFKNETVDIRSLLEKRFSNKFLDLVDHVFFFRPVSKSDFKRVIIEEVNNFVKILKNEKIDLFFEEAVIGYFQKHIY
ENGLGIRGIRKIVIKEIGSLLIDDLILKKFKENDKIRIFLDDTIKYELL

Sequences:

>Translated_769_residues
MFYNWCFMYNRRALNHLFFKSFLFFVERKHLFFTEEHIFYSLISDDEIRELLSLCALDFYSFNKILEEFFTKLPIRNADF
YDYFFKINDLYQEIIDTIFYYKKPYVLQEKDLLWVLIRKRKNTILDALLKSGFSLDIFDKIMEIYDYLGSNLDLGFLKNE
KLLTNDLFNKGIDKYGGLNIFEEDYFKLEQDDDSLDENNLVDDFLVNVIDNLDPNLATNPLIGRKKELYTLIQIMLRKHK
SNPIVFGEPGVGKTILLQGLAYIIREGQVPHELIDCEVYSLDIGRLISGTRYRGDLENRVNKLLDFLHFKKKVILFIDEI
HMIVGAGATSFSNIDVSNLLKPILTLGKIKFIGATTKNEYKKFFLKDKALLRRFHGVELKEPSLEDTYHILKGAKEQYEK
HHHVEYTDEAIWVAITMSKYIKDRALPDKAFDLLDGLGSKFKLEGNKKVITGDDVRDFVKYMVGTSIFNFDDYDQDLLMN
LEHKIRTSMIIDESILSELLLHIKLLRIKFFFKNSTLGIFILIGSSDVDKNKLACVLSEELNMPKLTLGMSEYCDFDGIN
RLIGPVYGSEAYDEPTKFFRFLNESLNSIIVLSDFDKSSKRVIDFFFEGFNTGRLFDNFGRSVSLSGSIIIIDINIEYRE
LDGIGFKNETVDIRSLLEKRFSNKFLDLVDHVFFFRPVSKSDFKRVIIEEVNNFVKILKNEKIDLFFEEAVIGYFQKHIY
ENGLGIRGIRKIVIKEIGSLLIDDLILKKFKENDKIRIFLDDTIKYELL
>Mature_769_residues
MFYNWCFMYNRRALNHLFFKSFLFFVERKHLFFTEEHIFYSLISDDEIRELLSLCALDFYSFNKILEEFFTKLPIRNADF
YDYFFKINDLYQEIIDTIFYYKKPYVLQEKDLLWVLIRKRKNTILDALLKSGFSLDIFDKIMEIYDYLGSNLDLGFLKNE
KLLTNDLFNKGIDKYGGLNIFEEDYFKLEQDDDSLDENNLVDDFLVNVIDNLDPNLATNPLIGRKKELYTLIQIMLRKHK
SNPIVFGEPGVGKTILLQGLAYIIREGQVPHELIDCEVYSLDIGRLISGTRYRGDLENRVNKLLDFLHFKKKVILFIDEI
HMIVGAGATSFSNIDVSNLLKPILTLGKIKFIGATTKNEYKKFFLKDKALLRRFHGVELKEPSLEDTYHILKGAKEQYEK
HHHVEYTDEAIWVAITMSKYIKDRALPDKAFDLLDGLGSKFKLEGNKKVITGDDVRDFVKYMVGTSIFNFDDYDQDLLMN
LEHKIRTSMIIDESILSELLLHIKLLRIKFFFKNSTLGIFILIGSSDVDKNKLACVLSEELNMPKLTLGMSEYCDFDGIN
RLIGPVYGSEAYDEPTKFFRFLNESLNSIIVLSDFDKSSKRVIDFFFEGFNTGRLFDNFGRSVSLSGSIIIIDINIEYRE
LDGIGFKNETVDIRSLLEKRFSNKFLDLVDHVFFFRPVSKSDFKRVIIEEVNNFVKILKNEKIDLFFEEAVIGYFQKHIY
ENGLGIRGIRKIVIKEIGSLLIDDLILKKFKENDKIRIFLDDTIKYELL

Specific function: ATP-dependent specificity component of the ClpP protease. It directs the protease to specific substrates. The primary function of the ClpA-ClpP complex appears to be the degradation of unfolded or abnormal proteins [H]

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Escherichia coli, GI1787109, Length=754, Percent_Identity=28.6472148541114, Blast_Score=341, Evalue=1e-94,
Organism=Escherichia coli, GI1788943, Length=256, Percent_Identity=43.75, Blast_Score=224, Evalue=2e-59,
Organism=Saccharomyces cerevisiae, GI6320464, Length=274, Percent_Identity=43.4306569343066, Blast_Score=206, Evalue=2e-53,
Organism=Saccharomyces cerevisiae, GI6323002, Length=219, Percent_Identity=42.9223744292237, Blast_Score=187, Evalue=5e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR013461
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 90038; Mature: 90038

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFYNWCFMYNRRALNHLFFKSFLFFVERKHLFFTEEHIFYSLISDDEIRELLSLCALDFY
CEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHEEEECCCHHHHHHHHHHHHHHH
SFNKILEEFFTKLPIRNADFYDYFFKINDLYQEIIDTIFYYKKPYVLQEKDLLWVLIRKR
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHH
KNTILDALLKSGFSLDIFDKIMEIYDYLGSNLDLGFLKNEKLLTNDLFNKGIDKYGGLNI
HHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHCCCHHHCCCCC
FEEDYFKLEQDDDSLDENNLVDDFLVNVIDNLDPNLATNPLIGRKKELYTLIQIMLRKHK
CHHHHHEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
SNPIVFGEPGVGKTILLQGLAYIIREGQVPHELIDCEVYSLDIGRLISGTRYRGDLENRV
CCCEEECCCCCCHHHHHHHHHHHHHCCCCCHHHHCCEEEEEEHHHHHCCCCCCCCHHHHH
NKLLDFLHFKKKVILFIDEIHMIVGAGATSFSNIDVSNLLKPILTLGKIKFIGATTKNEY
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCEEEEECCCHHHH
KKFFLKDKALLRRFHGVELKEPSLEDTYHILKGAKEQYEKHHHVEYTDEAIWVAITMSKY
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCHHHHHHHHCCCCCCCCEEEEEEEHHHH
IKDRALPDKAFDLLDGLGSKFKLEGNKKVITGDDVRDFVKYMVGTSIFNFDDYDQDLLMN
HHHHCCCHHHHHHHHCCCCEEEECCCCEEECCCCHHHHHHHHHCCCEECCCCCCHHHHHH
LEHKIRTSMIIDESILSELLLHIKLLRIKFFFKNSTLGIFILIGSSDVDKNKLACVLSEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCEEEEEEEECCCCCCCCEEEEEHHC
LNMPKLTLGMSEYCDFDGINRLIGPVYGSEAYDEPTKFFRFLNESLNSIIVLSDFDKSSK
CCCCEEECCHHHHCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHCEEEEEECCCCCHH
RVIDFFFEGFNTGRLFDNFGRSVSLSGSIIIIDINIEYRELDGIGFKNETVDIRSLLEKR
HHHHHHHHCCCCCCHHHHCCCEEEECCCEEEEEEEEEEEECCCCCCCCCCHHHHHHHHHH
FSNKFLDLVDHVFFFRPVSKSDFKRVIIEEVNNFVKILKNEKIDLFFEEAVIGYFQKHIY
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
ENGLGIRGIRKIVIKEIGSLLIDDLILKKFKENDKIRIFLDDTIKYELL
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCEEEECC
>Mature Secondary Structure
MFYNWCFMYNRRALNHLFFKSFLFFVERKHLFFTEEHIFYSLISDDEIRELLSLCALDFY
CEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHEEEECCCHHHHHHHHHHHHHHH
SFNKILEEFFTKLPIRNADFYDYFFKINDLYQEIIDTIFYYKKPYVLQEKDLLWVLIRKR
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHH
KNTILDALLKSGFSLDIFDKIMEIYDYLGSNLDLGFLKNEKLLTNDLFNKGIDKYGGLNI
HHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHCCCHHHCCCCC
FEEDYFKLEQDDDSLDENNLVDDFLVNVIDNLDPNLATNPLIGRKKELYTLIQIMLRKHK
CHHHHHEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
SNPIVFGEPGVGKTILLQGLAYIIREGQVPHELIDCEVYSLDIGRLISGTRYRGDLENRV
CCCEEECCCCCCHHHHHHHHHHHHHCCCCCHHHHCCEEEEEEHHHHHCCCCCCCCHHHHH
NKLLDFLHFKKKVILFIDEIHMIVGAGATSFSNIDVSNLLKPILTLGKIKFIGATTKNEY
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCEEEEECCCHHHH
KKFFLKDKALLRRFHGVELKEPSLEDTYHILKGAKEQYEKHHHVEYTDEAIWVAITMSKY
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCHHHHHHHHCCCCCCCCEEEEEEEHHHH
IKDRALPDKAFDLLDGLGSKFKLEGNKKVITGDDVRDFVKYMVGTSIFNFDDYDQDLLMN
HHHHCCCHHHHHHHHCCCCEEEECCCCEEECCCCHHHHHHHHHCCCEECCCCCCHHHHHH
LEHKIRTSMIIDESILSELLLHIKLLRIKFFFKNSTLGIFILIGSSDVDKNKLACVLSEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCEEEEEEEECCCCCCCCEEEEEHHC
LNMPKLTLGMSEYCDFDGINRLIGPVYGSEAYDEPTKFFRFLNESLNSIIVLSDFDKSSK
CCCCEEECCHHHHCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHCEEEEEECCCCCHH
RVIDFFFEGFNTGRLFDNFGRSVSLSGSIIIIDINIEYRELDGIGFKNETVDIRSLLEKR
HHHHHHHHCCCCCCHHHHCCCEEEECCCEEEEEEEEEEEECCCCCCCCCCHHHHHHHHHH
FSNKFLDLVDHVFFFRPVSKSDFKRVIIEEVNNFVKILKNEKIDLFFEEAVIGYFQKHIY
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
ENGLGIRGIRKIVIKEIGSLLIDDLILKKFKENDKIRIFLDDTIKYELL
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]