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The map label for this gene is lutB [H]

Identifier: 197119283

GI number: 197119283

Start: 3358410

End: 3360545

Strand: Direct

Name: lutB [H]

Synonym: Gbem_2911

Alternate gene names: 197119283

Gene position: 3358410-3360545 (Clockwise)

Preceding gene: 197119282

Following gene: 197119286

Centisome position: 72.77

GC content: 62.41

Gene sequence:

>2136_bases
ATGAAAAAAGAGTTCAAGGCATCGATCAACCGGGCCCTCAACGACGCCAACCTGACTGGCGCGCTGGGGAAGTTTTCTGA
AGCCTACAAGGTGAACCGCGCCAAGGCCTACGATGGGATGGACTTCGAGGCGCTCCGCTCCACCGTCGCCGAGGCGAAGT
CGAAGGCCGCCTGCCACCTGGACGAGGTAGCCGATGTCTTCAAGGCGAACGCCGAAGCGCTCGGCGCCAAGGTGTTCCGC
ACCCGCGACCCACAGGAGGTGAAGCGCTACATCCTGCAACTGGCCAAGGATAAAGGGGTCAGGAGCGTGGTGAAGTCGAA
GTCCATGGCGACGGAGGAGATCCACCTGAACCGTGCCCTGCTGGACGAGGGAATCTCGGTCGCCGAAACCGACCTGGGGG
AATGGATCATCCAGCTCGCCGGCCAAACCCCGTCGCACATGGTCATGCCGGCCATCCACATGACCAAGGAGGAGGTGGCG
GAGATCTTCAGCAAAGAGGTCGACGAGCGGCTCTCCACCGACATCCCGAGGCTGGTGAAGGTGGCCCGCAACGAACTCCG
CCCTAAGTTCCTGGCCGCGGACATGGGTATCTCCGGCGGCAACATAGCCGTCGCCGAGACCGGAAGCATCGTGCTTGTGA
CCAACGAGGGGAACGCGAGGCTCGTAACTTCCCTTCCCAGGATCCACGTGGCGCTGATCGGCGTCGAGAAACTGGTGGAG
AAGTTCGAGAGCGTCGCCCCCATCCTGGACGCGCTACCCAGGAGCGCCACGGCGCAGCTTCTCACCAGCTACGTCTCCAT
CATCACCGGCCCCACACCTAACGACGACGGGAGCGAAAAGGAGCTGCACATCATCCTGATGGACAACCGGCGCACTGAGA
TGGCGCAGGACCCCAAGTTCAAGCAGGCTCTGCAATGCATCCGCTGCGGCTCCTGCCTGAACGTCTGCCCGATCTTCCGG
CTGGTGGGGGGGCACGTCTTCGGCAGCATCTACACCGGGGGGATCGGCACCATCCTCACCGCCTGGTTCGACGAGCTGAA
GAAGTCCGAGGATATACAGGGGCTTTGCATCCAGTGCGGCAACTGCAAGGAGGTCTGCCCGGGCAAGCTCGACATACCCG
AGATGATCATGGAGATACGGCGCAGGCTGGTGCTGGAAAAGGGGCAGCCGCTGCTGCAGAAGGCGATATTCGGCGTGGTG
AACAACAGAAGGCTTTTCCACGGCATGCTGCGCGCCGCCTCCGTCGCCGCAAAGCCCTTCAGCTCCGCAGGGTTCATCCG
CCACCTGCCGCTGTTTCTGGCCGACCTAACCGACGGACGCAGCCTCCCGGCCATCGCGGAGAAGCCGTTCAGGGACATCT
TCCCGGAGATCGTGCAGCCGCAGGCAAAGGAAAAGGCCGTCTTCTACGCCGGCTGCCTGATCGACTTCGCCTACCCCGAG
ACGGGGGTCGCGCTGGTGAAGCTGCTGAATAAGGCGGGGATCGAGGTGGTCTTCCCCGAGGAGCAGACCTGCTGCGGAGC
CCCGGCGCTCTACAACGGGGCCTACGAGGTCGCGGCGCAAAACGCCGTGGACAACATACAAGCGCTCTTGCAGCAGGAGG
CGCAGTACGTGGTCTCCGCCTGCCCCACCTGCACGGTGGCGCTGGCGCACGAGTTCGGCAAGACCCTGGAAAGCCTGGGA
CAGACCGAGTGGATGGAAAAAGCGCAGGAGCTGGCCGCTAAGACGGTGGATCTCTCCACCCTCGTGAAGCGGTTGACCGA
TGAAGGAAGGCTGAGCTTTGAGGAAGGGGAAGGGCTTTCGAAAATCACCTACCACGACTCCTGCCATCTCAAGCGGACGC
TCAAGGTGTCGGAAGAGCCGCGCGAACTGCTGCAAAAGGCGGGTTACCAGCTGGAGGAGATGTTCGAGTGCGACATGTGC
TGCGGCATGGGAGGTTCCTACTCCATGAAGCTTCCCGAGATCTCGGCGCCAATACTCAAGCGGAAACTGCAGAACATCAA
GGAAACCGGGGCGCCGGTAGTGGCCATGGACTGCCCGGGGTGCGTGATGCAGATCCGCGGCGGATTCGATCAGCAAGAGG
GCGGGGTGAAGGTGAAGCATACCGCCGAGCTTTTGGCCGAGCGATTGAAAGGCTAG

Upstream 100 bases:

>100_bases
CCAGCCGCACCGCCGACATCGAGCGGGTGCTCACCATCGGGGTGCACGGCCCCCAACGTCTGGTCATCATCTTCGTGGAC
GGGCTTGAGGGGGTTAGCCG

Downstream 100 bases:

>100_bases
CAGCCATAGGTGCCATCGATTCCATGAATGTTGATCACAGTTGATCTTCGTCCACTACTCTCCCCCTCCCTCGACGGGAG
GGGGTCGGGGGGTGGGTGAA

Product: iron-sulfur cluster-binding DUF162/cysteine-rich domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 711; Mature: 711

Protein sequence:

>711_residues
MKKEFKASINRALNDANLTGALGKFSEAYKVNRAKAYDGMDFEALRSTVAEAKSKAACHLDEVADVFKANAEALGAKVFR
TRDPQEVKRYILQLAKDKGVRSVVKSKSMATEEIHLNRALLDEGISVAETDLGEWIIQLAGQTPSHMVMPAIHMTKEEVA
EIFSKEVDERLSTDIPRLVKVARNELRPKFLAADMGISGGNIAVAETGSIVLVTNEGNARLVTSLPRIHVALIGVEKLVE
KFESVAPILDALPRSATAQLLTSYVSIITGPTPNDDGSEKELHIILMDNRRTEMAQDPKFKQALQCIRCGSCLNVCPIFR
LVGGHVFGSIYTGGIGTILTAWFDELKKSEDIQGLCIQCGNCKEVCPGKLDIPEMIMEIRRRLVLEKGQPLLQKAIFGVV
NNRRLFHGMLRAASVAAKPFSSAGFIRHLPLFLADLTDGRSLPAIAEKPFRDIFPEIVQPQAKEKAVFYAGCLIDFAYPE
TGVALVKLLNKAGIEVVFPEEQTCCGAPALYNGAYEVAAQNAVDNIQALLQQEAQYVVSACPTCTVALAHEFGKTLESLG
QTEWMEKAQELAAKTVDLSTLVKRLTDEGRLSFEEGEGLSKITYHDSCHLKRTLKVSEEPRELLQKAGYQLEEMFECDMC
CGMGGSYSMKLPEISAPILKRKLQNIKETGAPVVAMDCPGCVMQIRGGFDQQEGGVKVKHTAELLAERLKG

Sequences:

>Translated_711_residues
MKKEFKASINRALNDANLTGALGKFSEAYKVNRAKAYDGMDFEALRSTVAEAKSKAACHLDEVADVFKANAEALGAKVFR
TRDPQEVKRYILQLAKDKGVRSVVKSKSMATEEIHLNRALLDEGISVAETDLGEWIIQLAGQTPSHMVMPAIHMTKEEVA
EIFSKEVDERLSTDIPRLVKVARNELRPKFLAADMGISGGNIAVAETGSIVLVTNEGNARLVTSLPRIHVALIGVEKLVE
KFESVAPILDALPRSATAQLLTSYVSIITGPTPNDDGSEKELHIILMDNRRTEMAQDPKFKQALQCIRCGSCLNVCPIFR
LVGGHVFGSIYTGGIGTILTAWFDELKKSEDIQGLCIQCGNCKEVCPGKLDIPEMIMEIRRRLVLEKGQPLLQKAIFGVV
NNRRLFHGMLRAASVAAKPFSSAGFIRHLPLFLADLTDGRSLPAIAEKPFRDIFPEIVQPQAKEKAVFYAGCLIDFAYPE
TGVALVKLLNKAGIEVVFPEEQTCCGAPALYNGAYEVAAQNAVDNIQALLQQEAQYVVSACPTCTVALAHEFGKTLESLG
QTEWMEKAQELAAKTVDLSTLVKRLTDEGRLSFEEGEGLSKITYHDSCHLKRTLKVSEEPRELLQKAGYQLEEMFECDMC
CGMGGSYSMKLPEISAPILKRKLQNIKETGAPVVAMDCPGCVMQIRGGFDQQEGGVKVKHTAELLAERLKG
>Mature_711_residues
MKKEFKASINRALNDANLTGALGKFSEAYKVNRAKAYDGMDFEALRSTVAEAKSKAACHLDEVADVFKANAEALGAKVFR
TRDPQEVKRYILQLAKDKGVRSVVKSKSMATEEIHLNRALLDEGISVAETDLGEWIIQLAGQTPSHMVMPAIHMTKEEVA
EIFSKEVDERLSTDIPRLVKVARNELRPKFLAADMGISGGNIAVAETGSIVLVTNEGNARLVTSLPRIHVALIGVEKLVE
KFESVAPILDALPRSATAQLLTSYVSIITGPTPNDDGSEKELHIILMDNRRTEMAQDPKFKQALQCIRCGSCLNVCPIFR
LVGGHVFGSIYTGGIGTILTAWFDELKKSEDIQGLCIQCGNCKEVCPGKLDIPEMIMEIRRRLVLEKGQPLLQKAIFGVV
NNRRLFHGMLRAASVAAKPFSSAGFIRHLPLFLADLTDGRSLPAIAEKPFRDIFPEIVQPQAKEKAVFYAGCLIDFAYPE
TGVALVKLLNKAGIEVVFPEEQTCCGAPALYNGAYEVAAQNAVDNIQALLQQEAQYVVSACPTCTVALAHEFGKTLESLG
QTEWMEKAQELAAKTVDLSTLVKRLTDEGRLSFEEGEGLSKITYHDSCHLKRTLKVSEEPRELLQKAGYQLEEMFECDMC
CGMGGSYSMKLPEISAPILKRKLQNIKETGAPVVAMDCPGCVMQIRGGFDQQEGGVKVKHTAELLAERLKG

Specific function: Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate [H]

COG id: COG1139

COG function: function code C; Uncharacterized conserved protein containing a ferredoxin-like domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Escherichia coli, GI1786498, Length=477, Percent_Identity=36.8972746331237, Blast_Score=290, Evalue=2e-79,
Organism=Escherichia coli, GI1788576, Length=427, Percent_Identity=26.463700234192, Blast_Score=123, Evalue=4e-29,
Organism=Escherichia coli, GI1786497, Length=244, Percent_Identity=32.7868852459016, Blast_Score=113, Evalue=4e-26,
Organism=Escherichia coli, GI48994913, Length=417, Percent_Identity=24.7002398081535, Blast_Score=106, Evalue=5e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017900
- InterPro:   IPR003741
- InterPro:   IPR004452
- InterPro:   IPR002698
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR022825 [H]

Pfam domain/function: PF02589 DUF162 [H]

EC number: NA

Molecular weight: Translated: 77904; Mature: 77904

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKEFKASINRALNDANLTGALGKFSEAYKVNRAKAYDGMDFEALRSTVAEAKSKAACHL
CCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHCCCCCCHHHHHHHHHHHHHHHHHHH
DEVADVFKANAEALGAKVFRTRDPQEVKRYILQLAKDKGVRSVVKSKSMATEEIHLNRAL
HHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
LDEGISVAETDLGEWIIQLAGQTPSHMVMPAIHMTKEEVAEIFSKEVDERLSTDIPRLVK
HHCCCCHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
VARNELRPKFLAADMGISGGNIAVAETGSIVLVTNEGNARLVTSLPRIHVALIGVEKLVE
HHHHHCCCHHHHHHCCCCCCCEEEEECCCEEEEECCCCCEEEECCCHHHHHHHHHHHHHH
KFESVAPILDALPRSATAQLLTSYVSIITGPTPNDDGSEKELHIILMDNRRTEMAQDPKF
HHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCHHHHCCCCH
KQALQCIRCGSCLNVCPIFRLVGGHVFGSIYTGGIGTILTAWFDELKKSEDIQGLCIQCG
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCHHHCCC
NCKEVCPGKLDIPEMIMEIRRRLVLEKGQPLLQKAIFGVVNNRRLFHGMLRAASVAAKPF
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCC
SSAGFIRHLPLFLADLTDGRSLPAIAEKPFRDIFPEIVQPQAKEKAVFYAGCLIDFAYPE
CCCCHHHHHHHHHHHCCCCCCCCHHHCCCHHHHHHHHCCCCCHHCEEEEEHHHEEECCCC
TGVALVKLLNKAGIEVVFPEEQTCCGAPALYNGAYEVAAQNAVDNIQALLQQEAQYVVSA
HHHHHHHHHHHCCCEEECCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
CPTCTVALAHEFGKTLESLGQTEWMEKAQELAAKTVDLSTLVKRLTDEGRLSFEEGEGLS
CCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCEEECCCCCCC
KITYHDSCHLKRTLKVSEEPRELLQKAGYQLEEMFECDMCCGMGGSYSMKLPEISAPILK
EEEECCCCCHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEECCCCHHHHHH
RKLQNIKETGAPVVAMDCPGCVMQIRGGFDQQEGGVKVKHTAELLAERLKG
HHHHHHHHCCCCEEEECCCCHHHHHCCCCCCCCCCEEEHHHHHHHHHHHCC
>Mature Secondary Structure
MKKEFKASINRALNDANLTGALGKFSEAYKVNRAKAYDGMDFEALRSTVAEAKSKAACHL
CCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHCCCCCCHHHHHHHHHHHHHHHHHHH
DEVADVFKANAEALGAKVFRTRDPQEVKRYILQLAKDKGVRSVVKSKSMATEEIHLNRAL
HHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
LDEGISVAETDLGEWIIQLAGQTPSHMVMPAIHMTKEEVAEIFSKEVDERLSTDIPRLVK
HHCCCCHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
VARNELRPKFLAADMGISGGNIAVAETGSIVLVTNEGNARLVTSLPRIHVALIGVEKLVE
HHHHHCCCHHHHHHCCCCCCCEEEEECCCEEEEECCCCCEEEECCCHHHHHHHHHHHHHH
KFESVAPILDALPRSATAQLLTSYVSIITGPTPNDDGSEKELHIILMDNRRTEMAQDPKF
HHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCHHHHCCCCH
KQALQCIRCGSCLNVCPIFRLVGGHVFGSIYTGGIGTILTAWFDELKKSEDIQGLCIQCG
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCHHHCCC
NCKEVCPGKLDIPEMIMEIRRRLVLEKGQPLLQKAIFGVVNNRRLFHGMLRAASVAAKPF
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCC
SSAGFIRHLPLFLADLTDGRSLPAIAEKPFRDIFPEIVQPQAKEKAVFYAGCLIDFAYPE
CCCCHHHHHHHHHHHCCCCCCCCHHHCCCHHHHHHHHCCCCCHHCEEEEEHHHEEECCCC
TGVALVKLLNKAGIEVVFPEEQTCCGAPALYNGAYEVAAQNAVDNIQALLQQEAQYVVSA
HHHHHHHHHHHCCCEEECCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
CPTCTVALAHEFGKTLESLGQTEWMEKAQELAAKTVDLSTLVKRLTDEGRLSFEEGEGLS
CCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCEEECCCCCCC
KITYHDSCHLKRTLKVSEEPRELLQKAGYQLEEMFECDMCCGMGGSYSMKLPEISAPILK
EEEECCCCCHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEECCCCHHHHHH
RKLQNIKETGAPVVAMDCPGCVMQIRGGFDQQEGGVKVKHTAELLAERLKG
HHHHHHHHCCCCEEEECCCCHHHHHCCCCCCCCCCEEEHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA