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The map label for this gene is appC [H]

Identifier: 197119019

GI number: 197119019

Start: 3058417

End: 3059259

Strand: Reverse

Name: appC [H]

Synonym: Gbem_2642

Alternate gene names: 197119019

Gene position: 3059259-3058417 (Counterclockwise)

Preceding gene: 197119020

Following gene: 197119018

Centisome position: 66.29

GC content: 65.01

Gene sequence:

>843_bases
ATGAACGGACCTTTCCGCGAGTTCTGGGAACGCTTCAGCGCCAACCGCTTCGCCCTGGCTGGCCTTTGGGTGATTGCCCT
TTTGTTCCTCCTTTCCTTCGCCGCCTCCTTCATAACCCCGTACGACCCGGACGCCATCGATGCCTGGCACGTGCTGCTCC
CCCCCTCCGCCGCGCACTGGTTCGGCACCGACGAATTGGGGCGCGACGTCCTCACCAGGGTGATCTTCGGCGCGCGCGTC
TCGCTCAAGGTCGGCTTCGTGGCGGTCGGTATCGCCGTGGCGGTCGGGACCGTGGTGGGGCTCTTCGCGGGATTCTACGG
CGGCTGGGTCGATTCGGTGCTGATGCGGATAGTGGACATCATGCTCTGCTTCCCCACCTTCTTCCTGATCCTGGCGGTGA
TCGCCATGCTGGAGCCTTCCATCTGGTACATCATGGTCATCATCGGACTTACCGGCTGGATGGGGGTGGCGCGCCTGGTG
CGGGCGGAGGTCCTTTCCCTGAAGAGCCGCGACTTCGTCTCCGCTGCGAGGGTGCTGGGGGCGTCGGATAGGCGCATCAT
CTTCCGGCACATCCTCCCCAACGCCCTCTCCCCGGTGCTGGTTTCCGCGACGCTCGGGGTGGCCGGAGCCATCCTCACCG
AGTCCGCGCTCTCCTTCCTCGGCATCGGGGTGCAGCCGCCGACTCCCAGTTGGGGCAACATCCTCACCTCCGGCAAGGAC
TACATCGAGTTCGCCTGGTGGCTTTCCCTGTTCCCGGGGGTGGCCATCCTGGTCACGGTCCTCTCCTACAACCTGGTGGG
CGAAGGTATCCGCGACGCGCTGGACCCGAGAAGGCAAAGGTAA

Upstream 100 bases:

>100_bases
CCTCGTGATCGGCGCCGGGCTCACGCTCGTCGGCAACCTTTTGGCCGACCTCTGCTATGCCTTCGCGGATCCCCGCATCC
GGCACGGGAGGGGCTAGCCC

Downstream 100 bases:

>100_bases
AAAACCGGTTCAACGTTCGACGTTCAACGTTCGACGTTGTCATCTGCTTTTGGCTCACGCGTCTCGACGGCTACAACACC
GGTTCGATGTTCAACGTTCG

Product: peptide ABC transporter membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MNGPFREFWERFSANRFALAGLWVIALLFLLSFAASFITPYDPDAIDAWHVLLPPSAAHWFGTDELGRDVLTRVIFGARV
SLKVGFVAVGIAVAVGTVVGLFAGFYGGWVDSVLMRIVDIMLCFPTFFLILAVIAMLEPSIWYIMVIIGLTGWMGVARLV
RAEVLSLKSRDFVSAARVLGASDRRIIFRHILPNALSPVLVSATLGVAGAILTESALSFLGIGVQPPTPSWGNILTSGKD
YIEFAWWLSLFPGVAILVTVLSYNLVGEGIRDALDPRRQR

Sequences:

>Translated_280_residues
MNGPFREFWERFSANRFALAGLWVIALLFLLSFAASFITPYDPDAIDAWHVLLPPSAAHWFGTDELGRDVLTRVIFGARV
SLKVGFVAVGIAVAVGTVVGLFAGFYGGWVDSVLMRIVDIMLCFPTFFLILAVIAMLEPSIWYIMVIIGLTGWMGVARLV
RAEVLSLKSRDFVSAARVLGASDRRIIFRHILPNALSPVLVSATLGVAGAILTESALSFLGIGVQPPTPSWGNILTSGKD
YIEFAWWLSLFPGVAILVTVLSYNLVGEGIRDALDPRRQR
>Mature_280_residues
MNGPFREFWERFSANRFALAGLWVIALLFLLSFAASFITPYDPDAIDAWHVLLPPSAAHWFGTDELGRDVLTRVIFGARV
SLKVGFVAVGIAVAVGTVVGLFAGFYGGWVDSVLMRIVDIMLCFPTFFLILAVIAMLEPSIWYIMVIIGLTGWMGVARLV
RAEVLSLKSRDFVSAARVLGASDRRIIFRHILPNALSPVLVSATLGVAGAILTESALSFLGIGVQPPTPSWGNILTSGKD
YIEFAWWLSLFPGVAILVTVLSYNLVGEGIRDALDPRRQR

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=275, Percent_Identity=41.8181818181818, Blast_Score=230, Evalue=1e-61,
Organism=Escherichia coli, GI1787760, Length=254, Percent_Identity=42.5196850393701, Blast_Score=219, Evalue=2e-58,
Organism=Escherichia coli, GI1789964, Length=283, Percent_Identity=43.8162544169611, Blast_Score=213, Evalue=2e-56,
Organism=Escherichia coli, GI1787498, Length=281, Percent_Identity=42.3487544483986, Blast_Score=191, Evalue=6e-50,
Organism=Escherichia coli, GI1789889, Length=238, Percent_Identity=38.655462184874, Blast_Score=170, Evalue=1e-43,
Organism=Escherichia coli, GI1788505, Length=226, Percent_Identity=38.0530973451327, Blast_Score=164, Evalue=9e-42,
Organism=Escherichia coli, GI1787549, Length=278, Percent_Identity=34.1726618705036, Blast_Score=145, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 30600; Mature: 30600

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNGPFREFWERFSANRFALAGLWVIALLFLLSFAASFITPYDPDAIDAWHVLLPPSAAHW
CCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCEEECCCCHHC
FGTDELGRDVLTRVIFGARVSLKVGFVAVGIAVAVGTVVGLFAGFYGGWVDSVLMRIVDI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLCFPTFFLILAVIAMLEPSIWYIMVIIGLTGWMGVARLVRAEVLSLKSRDFVSAARVLG
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ASDRRIIFRHILPNALSPVLVSATLGVAGAILTESALSFLGIGVQPPTPSWGNILTSGKD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCHH
YIEFAWWLSLFPGVAILVTVLSYNLVGEGIRDALDPRRQR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]