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The map label for this gene is ptsP [H]

Identifier: 197118893

GI number: 197118893

Start: 2916223

End: 2918565

Strand: Direct

Name: ptsP [H]

Synonym: Gbem_2516

Alternate gene names: 197118893

Gene position: 2916223-2918565 (Clockwise)

Preceding gene: 197118891

Following gene: 197118895

Centisome position: 63.19

GC content: 62.7

Gene sequence:

>2343_bases
ATGCCGGAGGAGACAGGGGAACAACTGGGACTGAGGACACTGGAGGACATCAGCATGCTGATCCTTCACTCCCACGATCT
GCAGGAGACCCTGGATAATATAGTCAACCTCGTTGCTAAGAGAATGTCCTCCGACGTCTGTTCCATCTACCTTCTGGAGG
AGGACGGCGAGACCCTGAGGCTGCACGCGACCCGCGGTCTCTCCAGGCTCTCCGTCGGCATCACCATGAAGACCTCGGAA
GGCCTCACCGGCCTCGCCATCGAGCAGCGCGGCGTAGTGGCGACGGACAACGCGCCGCGGCACCCGCGCTACAAGTACTT
CAGGCAGACCAAGGAGGAAAAGGTCCTTTCCTTCTTAGGCGTCCCCTTCTTCGAACGCAACAACCCCATCGGCGTCCTGG
TCATACAAAACCGCGACGCGCGCACCTTCACCTCCCAGGAAATCAGCGCCGTCTCCACCATCGCCTGGCAGATCTCCAGC
ATCGTTTCCAACGCAAAACTCCTCGACTCCGTCAGGAAGAAGGAAGAGGAGCGGGCTTTTTACGCAGCCGAGGTGGACCG
GCTCCGCAAAACCGGGGTACTCAAGGATACCGGCCGCGCGAGCCGCAAGAGCCAGGGATCGGGAGTATTGACCGGGATCG
GGATTTCCCCCGGTTTCGCAGTGGGGAGAATTTCGGTACTGCACCGTGGTGCGAGCGAAGAGGCGGTCCTGGAACAGGCG
CGGCCGCGCGCCGAGGAACAGACCCGCTTCCTGCACGCGCTGGAGAAGGCGCGCATCCAGACCATCTATATGGAAAAGCG
GGTGGGCCAGATCCTATCCGAGGCCGACGCCGCCATCTTCCACAGCCACCTGATGATACTGGAGGACCGCGGCTTCATCG
GGAAGATCGGCGCGCTGATCGACGAGGGGCTGGGTGCCCAAACCGCGGTAAGCCAGGTGGTGGACAGCTACGTGGCGGCC
TTCGCCCGGATGCAGGACCCCTACCTGCGCGAGCGCAGCGCCGACATGGAGGACATCGGGCGCAGGATCTGCGACGCGCT
GAACGGCAGCAACCACAAGCACAGGGAACGCCTGCGCGACCCGCGGATCATCATCGCCCGGGAACTGCTCCCCTCCGACC
TCGCCATCATGGACCACGGCAAGGTGACCGGCATCGCCACCGAGAAGGGGAACCAGAACGCCCACGCGGCGATCATGGCC
CGGGCGCTCGGCATTCCTGCCGTCTTCGGGGTAGAGGGGCTGTTGAAAAAGGTCGGGGCTCGCTGCGAGGTGGTCGTTGA
CGGCAACTCCGGCTGCGTCTACGTAAACCCGGACCAACGCATCAAGAAGGAATATCAGCGGCTGCAGGGGGAATTCGACC
AGAAGCAGCGCGAGCTGGAAGGTATCCGGGACCTACCCGCCGTGACCACCGACGGCTGCACCGTCTCTCTTCTGGCCAAC
ATCGGACTTCTGAGCGATTTGAGGGTAGCGCAGGCGCACGGAGCCGAGGGGGTCGGGCTGTACCGGACCGAGTTCCCGTT
CATGAGCCGCAACTCGTTCCCCGGGCGCGTGGAGCAGGCCGCCATCTACCGCAAGGTGCTGGAAGGGTTCCCAGGGCTCC
CGGTCACCATCAGGACCCTCGACATAGGCGGAGACAAGGAGCTTTCCTACTTCCCCCACCCAAAGGAAGACAACCCCTTC
CTGGGGTGGCGCTCCATGCGCATCTCACTCGACCGCGAGGACATCTTCCGCGAGCAGTTGGCTGCGGTGCTTTTGGCGTC
CGCCAGCGGCAGGTGCAACATCATGTTCCCCATGATCTCCGGCGTGGACGAAGTGCGCCGCATCAAGGGGATACTGGAAC
AAGTGAAAGAAGAGCTGAGAAAAGATGGGAAGGAATTCGCCCAGGATATTGGGCTCGGGGTCATGGTAGAGCTGCCGGCG
GCGGTGCTGGTAGCGGAGATGCTGGCCCGCGAGGTCGATTACCTGAGCATCGGGACCAACGACCTGATCCAGTACACCCT
TGCCTGCGACAGGAACAATCCGCTGGTGAAGAAGTGGTACGACCCGTACCATCCTGCGGTCCTGCACTCGATCAAGAAGG
TGGCGCAAGCGGCTGCGGGCGCGGGGAAGCCGGCGTCTTTGTGCGGCGAGATGGCGGGAGAACCGATCAACGCGGTCCTT
TTGCTGGGGCTTGGGATACGCTGCTTCAGCCTTTCCGCGCCGAACATACCGCGCGTGAAAGAGGCCATACGCGCCATTTC
CCTGGGGCAGGCGGAACAGATAGCCGGACAGGTGCTGCGGATGGAAAGTGCCCTCTCCATCAAGAGCTACCTGGAATCGG
TACAGCGCGAGCTGGGGCTGTAA

Upstream 100 bases:

>100_bases
TGCTTTGCCATCTTAAACGCCCGTTAAAATAGCATTAAAATACTTCACATATCATTTTTCTCATTTATACTGCCCCGAGA
ACGCCACAAAGGGGATGAGA

Downstream 100 bases:

>100_bases
GGCACAAGAGACAGCAGCCGGGGGCCGGATTATAGATCCCGGTCCCCGGCCATGTATCTCCAACAAGGGAAGGTCGATCT
TTCGTTGTCAATTGTCAATT

Product: GAF domain-containing phosphoenolpyruvate--protein phosphotransferase PtsP

Products: NA

Alternate protein names: Phosphotransferase system, enzyme I [H]

Number of amino acids: Translated: 780; Mature: 779

Protein sequence:

>780_residues
MPEETGEQLGLRTLEDISMLILHSHDLQETLDNIVNLVAKRMSSDVCSIYLLEEDGETLRLHATRGLSRLSVGITMKTSE
GLTGLAIEQRGVVATDNAPRHPRYKYFRQTKEEKVLSFLGVPFFERNNPIGVLVIQNRDARTFTSQEISAVSTIAWQISS
IVSNAKLLDSVRKKEEERAFYAAEVDRLRKTGVLKDTGRASRKSQGSGVLTGIGISPGFAVGRISVLHRGASEEAVLEQA
RPRAEEQTRFLHALEKARIQTIYMEKRVGQILSEADAAIFHSHLMILEDRGFIGKIGALIDEGLGAQTAVSQVVDSYVAA
FARMQDPYLRERSADMEDIGRRICDALNGSNHKHRERLRDPRIIIARELLPSDLAIMDHGKVTGIATEKGNQNAHAAIMA
RALGIPAVFGVEGLLKKVGARCEVVVDGNSGCVYVNPDQRIKKEYQRLQGEFDQKQRELEGIRDLPAVTTDGCTVSLLAN
IGLLSDLRVAQAHGAEGVGLYRTEFPFMSRNSFPGRVEQAAIYRKVLEGFPGLPVTIRTLDIGGDKELSYFPHPKEDNPF
LGWRSMRISLDREDIFREQLAAVLLASASGRCNIMFPMISGVDEVRRIKGILEQVKEELRKDGKEFAQDIGLGVMVELPA
AVLVAEMLAREVDYLSIGTNDLIQYTLACDRNNPLVKKWYDPYHPAVLHSIKKVAQAAAGAGKPASLCGEMAGEPINAVL
LLGLGIRCFSLSAPNIPRVKEAIRAISLGQAEQIAGQVLRMESALSIKSYLESVQRELGL

Sequences:

>Translated_780_residues
MPEETGEQLGLRTLEDISMLILHSHDLQETLDNIVNLVAKRMSSDVCSIYLLEEDGETLRLHATRGLSRLSVGITMKTSE
GLTGLAIEQRGVVATDNAPRHPRYKYFRQTKEEKVLSFLGVPFFERNNPIGVLVIQNRDARTFTSQEISAVSTIAWQISS
IVSNAKLLDSVRKKEEERAFYAAEVDRLRKTGVLKDTGRASRKSQGSGVLTGIGISPGFAVGRISVLHRGASEEAVLEQA
RPRAEEQTRFLHALEKARIQTIYMEKRVGQILSEADAAIFHSHLMILEDRGFIGKIGALIDEGLGAQTAVSQVVDSYVAA
FARMQDPYLRERSADMEDIGRRICDALNGSNHKHRERLRDPRIIIARELLPSDLAIMDHGKVTGIATEKGNQNAHAAIMA
RALGIPAVFGVEGLLKKVGARCEVVVDGNSGCVYVNPDQRIKKEYQRLQGEFDQKQRELEGIRDLPAVTTDGCTVSLLAN
IGLLSDLRVAQAHGAEGVGLYRTEFPFMSRNSFPGRVEQAAIYRKVLEGFPGLPVTIRTLDIGGDKELSYFPHPKEDNPF
LGWRSMRISLDREDIFREQLAAVLLASASGRCNIMFPMISGVDEVRRIKGILEQVKEELRKDGKEFAQDIGLGVMVELPA
AVLVAEMLAREVDYLSIGTNDLIQYTLACDRNNPLVKKWYDPYHPAVLHSIKKVAQAAAGAGKPASLCGEMAGEPINAVL
LLGLGIRCFSLSAPNIPRVKEAIRAISLGQAEQIAGQVLRMESALSIKSYLESVQRELGL
>Mature_779_residues
PEETGEQLGLRTLEDISMLILHSHDLQETLDNIVNLVAKRMSSDVCSIYLLEEDGETLRLHATRGLSRLSVGITMKTSEG
LTGLAIEQRGVVATDNAPRHPRYKYFRQTKEEKVLSFLGVPFFERNNPIGVLVIQNRDARTFTSQEISAVSTIAWQISSI
VSNAKLLDSVRKKEEERAFYAAEVDRLRKTGVLKDTGRASRKSQGSGVLTGIGISPGFAVGRISVLHRGASEEAVLEQAR
PRAEEQTRFLHALEKARIQTIYMEKRVGQILSEADAAIFHSHLMILEDRGFIGKIGALIDEGLGAQTAVSQVVDSYVAAF
ARMQDPYLRERSADMEDIGRRICDALNGSNHKHRERLRDPRIIIARELLPSDLAIMDHGKVTGIATEKGNQNAHAAIMAR
ALGIPAVFGVEGLLKKVGARCEVVVDGNSGCVYVNPDQRIKKEYQRLQGEFDQKQRELEGIRDLPAVTTDGCTVSLLANI
GLLSDLRVAQAHGAEGVGLYRTEFPFMSRNSFPGRVEQAAIYRKVLEGFPGLPVTIRTLDIGGDKELSYFPHPKEDNPFL
GWRSMRISLDREDIFREQLAAVLLASASGRCNIMFPMISGVDEVRRIKGILEQVKEELRKDGKEFAQDIGLGVMVELPAA
VLVAEMLAREVDYLSIGTNDLIQYTLACDRNNPLVKKWYDPYHPAVLHSIKKVAQAAAGAGKPASLCGEMAGEPINAVLL
LGLGIRCFSLSAPNIPRVKEAIRAISLGQAEQIAGQVLRMESALSIKSYLESVQRELGL

Specific function: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their tr

COG id: COG3605

COG function: function code T; Signal transduction protein containing GAF and PtsI domains

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PEP-utilizing enzyme family [H]

Homologues:

Organism=Escherichia coli, GI1788756, Length=556, Percent_Identity=42.2661870503597, Blast_Score=430, Evalue=1e-121,
Organism=Escherichia coli, GI1789193, Length=784, Percent_Identity=33.5459183673469, Blast_Score=404, Evalue=1e-113,
Organism=Escherichia coli, GI1788726, Length=580, Percent_Identity=33.6206896551724, Blast_Score=296, Evalue=3e-81,
Organism=Escherichia coli, GI48994992, Length=501, Percent_Identity=33.1337325349301, Blast_Score=280, Evalue=3e-76,
Organism=Escherichia coli, GI1787994, Length=405, Percent_Identity=25.9259259259259, Blast_Score=89, Evalue=1e-18,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2659 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 4,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008279
- InterPro:   IPR006318
- InterPro:   IPR018274
- InterPro:   IPR023151
- InterPro:   IPR000121
- InterPro:   IPR008731
- InterPro:   IPR015813 [H]

Pfam domain/function: PF05524 PEP-utilisers_N; PF00391 PEP-utilizers; PF02896 PEP-utilizers_C [H]

EC number: =2.7.3.9 [H]

Molecular weight: Translated: 85946; Mature: 85815

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: PS00742 PEP_ENZYMES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEETGEQLGLRTLEDISMLILHSHDLQETLDNIVNLVAKRMSSDVCSIYLLEEDGETLR
CCCCCCHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEE
LHATRGLSRLSVGITMKTSEGLTGLAIEQRGVVATDNAPRHPRYKYFRQTKEEKVLSFLG
EEECCCCCEEEEEEEEECCCCCCEEEEECCCEEECCCCCCCCHHHHHHHHHHHHHHHHHC
VPFFERNNPIGVLVIQNRDARTFTSQEISAVSTIAWQISSIVSNAKLLDSVRKKEEERAF
CCCEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YAAEVDRLRKTGVLKDTGRASRKSQGSGVLTGIGISPGFAVGRISVLHRGASEEAVLEQA
HHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHCCCCHHHHHHHH
RPRAEEQTRFLHALEKARIQTIYMEKRVGQILSEADAAIFHSHLMILEDRGFIGKIGALI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHH
DEGLGAQTAVSQVVDSYVAAFARMQDPYLRERSADMEDIGRRICDALNGSNHKHRERLRD
HCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHCC
PRIIIARELLPSDLAIMDHGKVTGIATEKGNQNAHAAIMARALGIPAVFGVEGLLKKVGA
CCEEEEHHHCCCCCEEEECCCEEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCC
RCEVVVDGNSGCVYVNPDQRIKKEYQRLQGEFDQKQRELEGIRDLPAVTTDGCTVSLLAN
EEEEEEECCCCEEEECCHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHC
IGLLSDLRVAQAHGAEGVGLYRTEFPFMSRNSFPGRVEQAAIYRKVLEGFPGLPVTIRTL
CCHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEE
DIGGDKELSYFPHPKEDNPFLGWRSMRISLDREDIFREQLAAVLLASASGRCNIMFPMIS
ECCCCCCCCCCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHCCCCCEEEEEHHHC
GVDEVRRIKGILEQVKEELRKDGKEFAQDIGLGVMVELPAAVLVAEMLAREVDYLSIGTN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHCCEEECCCH
DLIQYTLACDRNNPLVKKWYDPYHPAVLHSIKKVAQAAAGAGKPASLCGEMAGEPINAVL
HHEEEEEEECCCCCCHHHCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHH
LLGLGIRCFSLSAPNIPRVKEAIRAISLGQAEQIAGQVLRMESALSIKSYLESVQRELGL
HHHCCCEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PEETGEQLGLRTLEDISMLILHSHDLQETLDNIVNLVAKRMSSDVCSIYLLEEDGETLR
CCCCCHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEE
LHATRGLSRLSVGITMKTSEGLTGLAIEQRGVVATDNAPRHPRYKYFRQTKEEKVLSFLG
EEECCCCCEEEEEEEEECCCCCCEEEEECCCEEECCCCCCCCHHHHHHHHHHHHHHHHHC
VPFFERNNPIGVLVIQNRDARTFTSQEISAVSTIAWQISSIVSNAKLLDSVRKKEEERAF
CCCEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YAAEVDRLRKTGVLKDTGRASRKSQGSGVLTGIGISPGFAVGRISVLHRGASEEAVLEQA
HHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHCCCCHHHHHHHH
RPRAEEQTRFLHALEKARIQTIYMEKRVGQILSEADAAIFHSHLMILEDRGFIGKIGALI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHH
DEGLGAQTAVSQVVDSYVAAFARMQDPYLRERSADMEDIGRRICDALNGSNHKHRERLRD
HCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHCC
PRIIIARELLPSDLAIMDHGKVTGIATEKGNQNAHAAIMARALGIPAVFGVEGLLKKVGA
CCEEEEHHHCCCCCEEEECCCEEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCC
RCEVVVDGNSGCVYVNPDQRIKKEYQRLQGEFDQKQRELEGIRDLPAVTTDGCTVSLLAN
EEEEEEECCCCEEEECCHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHC
IGLLSDLRVAQAHGAEGVGLYRTEFPFMSRNSFPGRVEQAAIYRKVLEGFPGLPVTIRTL
CCHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEE
DIGGDKELSYFPHPKEDNPFLGWRSMRISLDREDIFREQLAAVLLASASGRCNIMFPMIS
ECCCCCCCCCCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHCCCCCEEEEEHHHC
GVDEVRRIKGILEQVKEELRKDGKEFAQDIGLGVMVELPAAVLVAEMLAREVDYLSIGTN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHCCEEECCCH
DLIQYTLACDRNNPLVKKWYDPYHPAVLHSIKKVAQAAAGAGKPASLCGEMAGEPINAVL
HHEEEEEEECCCCCCHHHCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHH
LLGLGIRCFSLSAPNIPRVKEAIRAISLGQAEQIAGQVLRMESALSIKSYLESVQRELGL
HHHCCCEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2457575; 2960675; 9205837; 9278503; 2411636; 3290198; 9298646; 7876255; 8805571; 9054557; 9541412; 10048929 [H]