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The map label for this gene is zraS [C]

Identifier: 197118785

GI number: 197118785

Start: 2784566

End: 2786887

Strand: Direct

Name: zraS [C]

Synonym: Gbem_2406

Alternate gene names: 197118785

Gene position: 2784566-2786887 (Clockwise)

Preceding gene: 197118782

Following gene: 197118786

Centisome position: 60.34

GC content: 60.47

Gene sequence:

>2322_bases
ATGAAACACGCACTGCGTATCCTGATCGTGGACGATTCCCCCGAAGATGCCGCACTCATCGTGCGTCAACTGCAGGGAGA
GTTCTCTATTAGCTACGAGCGCGTCGAGACCCCTGACGAAATGGAGGCGGCACTGGACAAGGGGGGATGGCACATCGTCA
TCTCGGACTACGTCATGCCCAAGTTCAGCGGGCTCGCGGCGCTCAAGCTTCTTCACGACCGGGGAATGGACCTCCCTTTC
ATCATGGTCTCCGGGCAGATGGGAGAGGACGCCGCCGTAGAGGCGATGCGAGCCGGCGCACATGACTACTTGCTGAAGGA
CAGGCTCTCCAGGCTGATCCCCGCGATCAAGCGGGAATTGAACGACGCCGTGGTGCGCCGCGAGAGGAGAATGGCCGAGG
AGGCCCTCTCGGCGACGGAGGCGCGCTTCCACAGCCTGGTGGAGCAGTCCCTGGTCGGCATATTCATGCTGCAGGACGAC
GTCTTCATCTACGTGAACCCCAAGTTCGGCGAGATCTTCGCCTACGAGCCGCAACAGCTGATCGAATCGAGATCTCTGCT
GGAACTGGTGGCGCCGGAAGATCAGATCAGGGTGATGACCCGGTTTCTGCGCCCCCTCATGGAGGAAAGCGACAGTCTGC
ACTTCTTCTTCCGAGGCAAGCGCCGCGACGGGTCCCTGATCGATCTCGAGGTGAACGGCACCCGGACCAGGGTAAACGGC
AGCGCTGCCATCATAGGGACCCTGCTCGACATAACCGAGCGCAAACGCGCCGAAGCGGAACTGAGCAAGCTGTGGCGCGC
CGTCGAGCAAAGCCCGGTATCGGTGGTGATAACAGATCTCTTCGGCAGGATCGAGTACGTGAACCCGAAGTTCATCGAGG
TGACCGGCTACGCCGAGGAGGAACTGATCGGGAAAAACCCGAGCATCCTGAAATCCGGGATGACCGACGCCAAGGTGTAC
GAGGAGCTCTGGTCTACAGTAACCTCTGGCCGGGAGTGGCACGGCGAGCTGCACAACAAGAAAAAGAACGGGGAGCTATT
CTGGGAAAACGGGCATATCTCCGCCATCAAGAACGCCGAGGGGCAGATCACCCATTTCGTCGGGGTCAAGGAGGACGTAA
CCGAGAGAAAGCTTGCCATCGACCAGCTGAGGCAGGTACAAAAGATGGAGGCCATAGGCCAGCTGGCAGGCGGCATCGCC
CACGACTTCAACAACCTCCTCACCGTCATCAACGGTTATTCGACGCTCCTGGTGAGATCCCTCGACAAGGGTTCGCCCAC
GCACAAGGAAGCGGAGCAGATCCTGCGTGCCGGCGAGCGTGCCGCAGATCTTACCAGGCAGCTGTTGAGCTTCAGCAGAA
GGCAGATCATGGAGCCGAGGGTGCTGGACATCAACAAGCAGGTGAGAGCGGTACAGAAGATGCTGGAACGGCTGATCGGG
GAGCATATCGGGCTCGTCACCACCCTCTCCGAGGACGCCGGCTTCATCAGGATGGACCCGGGGCAGATGGAACAGATCGT
CATGAACCTGATCGTCAACGCCCGCGACGCCTCGGAGACCGGCGGGGTGATCACCATGGCCACGGAGAAGGTCGACCTGG
ACCAGAATTTCTCACACCTGCACCCCGGGTCGGTTCCCGGAAGCTACGTCAGGCTGAGCGTGGCGGACCAGGGGCAAGGG
ATGACCGAGGAGGTAAAGCAGCGCCTCTTCGAACCCTTCTTCACCACGAAGGAGATGGGTCGCGGCACGGGCTTGGGTCT
CGCCACCGTGTACGGCATCGTGAAGCAAAGCGGAGGTTACATCGAGGTGGTCAGCGAACCGGGACAGGGAGCCTGCTTCA
ACATCTATCTCCCCCGCGCCTCGGAGCCCGCCCCCGCGCCGCCTGCGCCGCCGGTCGACGAAGAGATAGATTCCTCCCAC
GTCATACTCGTCGTGGAGGACGAACCGGGGGTGCTCAACCTGGTGGTGCACACCTTGCGCATGCGTGGTTTCACCGTCTA
TGAAGCCACGGACCCGGACCAGGGGATCACCCTTTTCGAGAAGCACGCCACTGAGATTGACATGCTCCTCACCGACGTGG
TAATGCCGTTCATGAGCGGCCCTGCCCTGGCTGAGCTGTTGCTCTCCAAAAAACCGGGATTGAAGGTGCTGTTCACGTCC
GGGCACACCGACGACAGGGCAGGTTTCGAGAAAATATTGGAAAAAGGGATGCAGTTCCTGCCCAAACCGTTTGCCAGCGA
CGCCCTGATCCGAAAGGTGAGGGACACCCTGAACGGAGGCACTGCAAAGACGGCAGGAGCGATTTCAGGAGGTAGCGATT
GA

Upstream 100 bases:

>100_bases
CGCTATTTTTTTCAGTGAAGCCGCTAAACATATCCGGAACCGCCGCCGATAAGAAAGAAAAGCGCAATTTTCAACCTGTA
CTTCAGAGGCAGGCCCATTG

Downstream 100 bases:

>100_bases
AAGGAAACATCTTAATAGCCGATGACGAGGACATGATCAGGGAACTGATCAACATCACCCTGTCAAAGGAAGGCTTCACC
TGCTTCCAGGCCGCAAGCGC

Product: response receiver sensor histidine kinase response regulator

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 773; Mature: 773

Protein sequence:

>773_residues
MKHALRILIVDDSPEDAALIVRQLQGEFSISYERVETPDEMEAALDKGGWHIVISDYVMPKFSGLAALKLLHDRGMDLPF
IMVSGQMGEDAAVEAMRAGAHDYLLKDRLSRLIPAIKRELNDAVVRRERRMAEEALSATEARFHSLVEQSLVGIFMLQDD
VFIYVNPKFGEIFAYEPQQLIESRSLLELVAPEDQIRVMTRFLRPLMEESDSLHFFFRGKRRDGSLIDLEVNGTRTRVNG
SAAIIGTLLDITERKRAEAELSKLWRAVEQSPVSVVITDLFGRIEYVNPKFIEVTGYAEEELIGKNPSILKSGMTDAKVY
EELWSTVTSGREWHGELHNKKKNGELFWENGHISAIKNAEGQITHFVGVKEDVTERKLAIDQLRQVQKMEAIGQLAGGIA
HDFNNLLTVINGYSTLLVRSLDKGSPTHKEAEQILRAGERAADLTRQLLSFSRRQIMEPRVLDINKQVRAVQKMLERLIG
EHIGLVTTLSEDAGFIRMDPGQMEQIVMNLIVNARDASETGGVITMATEKVDLDQNFSHLHPGSVPGSYVRLSVADQGQG
MTEEVKQRLFEPFFTTKEMGRGTGLGLATVYGIVKQSGGYIEVVSEPGQGACFNIYLPRASEPAPAPPAPPVDEEIDSSH
VILVVEDEPGVLNLVVHTLRMRGFTVYEATDPDQGITLFEKHATEIDMLLTDVVMPFMSGPALAELLLSKKPGLKVLFTS
GHTDDRAGFEKILEKGMQFLPKPFASDALIRKVRDTLNGGTAKTAGAISGGSD

Sequences:

>Translated_773_residues
MKHALRILIVDDSPEDAALIVRQLQGEFSISYERVETPDEMEAALDKGGWHIVISDYVMPKFSGLAALKLLHDRGMDLPF
IMVSGQMGEDAAVEAMRAGAHDYLLKDRLSRLIPAIKRELNDAVVRRERRMAEEALSATEARFHSLVEQSLVGIFMLQDD
VFIYVNPKFGEIFAYEPQQLIESRSLLELVAPEDQIRVMTRFLRPLMEESDSLHFFFRGKRRDGSLIDLEVNGTRTRVNG
SAAIIGTLLDITERKRAEAELSKLWRAVEQSPVSVVITDLFGRIEYVNPKFIEVTGYAEEELIGKNPSILKSGMTDAKVY
EELWSTVTSGREWHGELHNKKKNGELFWENGHISAIKNAEGQITHFVGVKEDVTERKLAIDQLRQVQKMEAIGQLAGGIA
HDFNNLLTVINGYSTLLVRSLDKGSPTHKEAEQILRAGERAADLTRQLLSFSRRQIMEPRVLDINKQVRAVQKMLERLIG
EHIGLVTTLSEDAGFIRMDPGQMEQIVMNLIVNARDASETGGVITMATEKVDLDQNFSHLHPGSVPGSYVRLSVADQGQG
MTEEVKQRLFEPFFTTKEMGRGTGLGLATVYGIVKQSGGYIEVVSEPGQGACFNIYLPRASEPAPAPPAPPVDEEIDSSH
VILVVEDEPGVLNLVVHTLRMRGFTVYEATDPDQGITLFEKHATEIDMLLTDVVMPFMSGPALAELLLSKKPGLKVLFTS
GHTDDRAGFEKILEKGMQFLPKPFASDALIRKVRDTLNGGTAKTAGAISGGSD
>Mature_773_residues
MKHALRILIVDDSPEDAALIVRQLQGEFSISYERVETPDEMEAALDKGGWHIVISDYVMPKFSGLAALKLLHDRGMDLPF
IMVSGQMGEDAAVEAMRAGAHDYLLKDRLSRLIPAIKRELNDAVVRRERRMAEEALSATEARFHSLVEQSLVGIFMLQDD
VFIYVNPKFGEIFAYEPQQLIESRSLLELVAPEDQIRVMTRFLRPLMEESDSLHFFFRGKRRDGSLIDLEVNGTRTRVNG
SAAIIGTLLDITERKRAEAELSKLWRAVEQSPVSVVITDLFGRIEYVNPKFIEVTGYAEEELIGKNPSILKSGMTDAKVY
EELWSTVTSGREWHGELHNKKKNGELFWENGHISAIKNAEGQITHFVGVKEDVTERKLAIDQLRQVQKMEAIGQLAGGIA
HDFNNLLTVINGYSTLLVRSLDKGSPTHKEAEQILRAGERAADLTRQLLSFSRRQIMEPRVLDINKQVRAVQKMLERLIG
EHIGLVTTLSEDAGFIRMDPGQMEQIVMNLIVNARDASETGGVITMATEKVDLDQNFSHLHPGSVPGSYVRLSVADQGQG
MTEEVKQRLFEPFFTTKEMGRGTGLGLATVYGIVKQSGGYIEVVSEPGQGACFNIYLPRASEPAPAPPAPPVDEEIDSSH
VILVVEDEPGVLNLVVHTLRMRGFTVYEATDPDQGITLFEKHATEIDMLLTDVVMPFMSGPALAELLLSKKPGLKVLFTS
GHTDDRAGFEKILEKGMQFLPKPFASDALIRKVRDTLNGGTAKTAGAISGGSD

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=257, Percent_Identity=29.1828793774319, Blast_Score=121, Evalue=2e-28,
Organism=Escherichia coli, GI1788549, Length=357, Percent_Identity=27.1708683473389, Blast_Score=120, Evalue=4e-28,
Organism=Escherichia coli, GI1788713, Length=418, Percent_Identity=25.5980861244019, Blast_Score=86, Evalue=1e-17,
Organism=Escherichia coli, GI87081816, Length=280, Percent_Identity=24.6428571428571, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1786912, Length=251, Percent_Identity=28.6852589641434, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI1790300, Length=247, Percent_Identity=28.3400809716599, Blast_Score=76, Evalue=1e-14,
Organism=Escherichia coli, GI145693157, Length=297, Percent_Identity=23.9057239057239, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI48994928, Length=425, Percent_Identity=24.7058823529412, Blast_Score=66, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 85785; Mature: 85785

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHALRILIVDDSPEDAALIVRQLQGEFSISYERVETPDEMEAALDKGGWHIVISDYVMP
CCCEEEEEEEECCCCHHHHHHHHHCCCCEEEEHHCCCCHHHHHHHCCCCCEEEEECCCCC
KFSGLAALKLLHDRGMDLPFIMVSGQMGEDAAVEAMRAGAHDYLLKDRLSRLIPAIKREL
CHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
NDAVVRRERRMAEEALSATEARFHSLVEQSLVGIFMLQDDVFIYVNPKFGEIFAYEPQQL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCEEEEECCCCCCEEEECHHHH
IESRSLLELVAPEDQIRVMTRFLRPLMEESDSLHFFFRGKRRDGSLIDLEVNGTRTRVNG
HHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCEEEEEECCCEEEECC
SAAIIGTLLDITERKRAEAELSKLWRAVEQSPVSVVITDLFGRIEYVNPKFIEVTGYAEE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHEEECCCEEEEEECCCHH
ELIGKNPSILKSGMTDAKVYEELWSTVTSGREWHGELHNKKKNGELFWENGHISAIKNAE
HHCCCCHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCEEEECCCEEEEECCC
GQITHFVGVKEDVTERKLAIDQLRQVQKMEAIGQLAGGIAHDFNNLLTVINGYSTLLVRS
CCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
LDKGSPTHKEAEQILRAGERAADLTRQLLSFSRRQIMEPRVLDINKQVRAVQKMLERLIG
CCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
EHIGLVTTLSEDAGFIRMDPGQMEQIVMNLIVNARDASETGGVITMATEKVDLDQNFSHL
HHCCEEEEECCCCCEEEECCHHHHHHHHHHHHCCCCCCCCCCEEEEEECEECCCCCCCCC
HPGSVPGSYVRLSVADQGQGMTEEVKQRLFEPFFTTKEMGRGTGLGLATVYGIVKQSGGY
CCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCE
IEVVSEPGQGACFNIYLPRASEPAPAPPAPPVDEEIDSSHVILVVEDEPGVLNLVVHTLR
EEEECCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHH
MRGFTVYEATDPDQGITLFEKHATEIDMLLTDVVMPFMSGPALAELLLSKKPGLKVLFTS
HCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCEEEEEC
GHTDDRAGFEKILEKGMQFLPKPFASDALIRKVRDTLNGGTAKTAGAISGGSD
CCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKHALRILIVDDSPEDAALIVRQLQGEFSISYERVETPDEMEAALDKGGWHIVISDYVMP
CCCEEEEEEEECCCCHHHHHHHHHCCCCEEEEHHCCCCHHHHHHHCCCCCEEEEECCCCC
KFSGLAALKLLHDRGMDLPFIMVSGQMGEDAAVEAMRAGAHDYLLKDRLSRLIPAIKREL
CHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
NDAVVRRERRMAEEALSATEARFHSLVEQSLVGIFMLQDDVFIYVNPKFGEIFAYEPQQL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCEEEEECCCCCCEEEECHHHH
IESRSLLELVAPEDQIRVMTRFLRPLMEESDSLHFFFRGKRRDGSLIDLEVNGTRTRVNG
HHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCEEEEEECCCEEEECC
SAAIIGTLLDITERKRAEAELSKLWRAVEQSPVSVVITDLFGRIEYVNPKFIEVTGYAEE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHEEECCCEEEEEECCCHH
ELIGKNPSILKSGMTDAKVYEELWSTVTSGREWHGELHNKKKNGELFWENGHISAIKNAE
HHCCCCHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCEEEECCCEEEEECCC
GQITHFVGVKEDVTERKLAIDQLRQVQKMEAIGQLAGGIAHDFNNLLTVINGYSTLLVRS
CCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
LDKGSPTHKEAEQILRAGERAADLTRQLLSFSRRQIMEPRVLDINKQVRAVQKMLERLIG
CCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
EHIGLVTTLSEDAGFIRMDPGQMEQIVMNLIVNARDASETGGVITMATEKVDLDQNFSHL
HHCCEEEEECCCCCEEEECCHHHHHHHHHHHHCCCCCCCCCCEEEEEECEECCCCCCCCC
HPGSVPGSYVRLSVADQGQGMTEEVKQRLFEPFFTTKEMGRGTGLGLATVYGIVKQSGGY
CCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCE
IEVVSEPGQGACFNIYLPRASEPAPAPPAPPVDEEIDSSHVILVVEDEPGVLNLVVHTLR
EEEECCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHH
MRGFTVYEATDPDQGITLFEKHATEIDMLLTDVVMPFMSGPALAELLLSKKPGLKVLFTS
HCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCEEEEEC
GHTDDRAGFEKILEKGMQFLPKPFASDALIRKVRDTLNGGTAKTAGAISGGSD
CCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA