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The map label for this gene is gcp [H]

Identifier: 197118670

GI number: 197118670

Start: 2658659

End: 2659705

Strand: Reverse

Name: gcp [H]

Synonym: Gbem_2289

Alternate gene names: 197118670

Gene position: 2659705-2658659 (Counterclockwise)

Preceding gene: 197118671

Following gene: 197118669

Centisome position: 57.63

GC content: 65.81

Gene sequence:

>1047_bases
GTGCCCTCTCTATTTTTTATGCTAGTTCTTGCTTTGGAATCATCCTGCGACGAAACGGCAGCCGCTGTGGTCAAGGACGG
CCGCACCGTCCTCTCCAGCATCGTCGCCTCTCAGATCAGCGTCCACGCCGAATACGGCGGCGTGGTCCCCGAGATAGCAT
CCCGAAAGCACCTGGAGTCCGTCTCCTTCGTGGTGGAACAGGCGCTCGCCGAGGCTGGCGTTGGTCTCGACCGGATCGAG
GGGATCGCCGTGACCCAGGGGCCGGGCCTTGCCGGAGCGCTCCTGGTGGGGATCTCCGTCGCCAAGGGGCTCGCTTTCGG
CCGCTCGCTCCCGCTTGTTGGGGTGAACCACATCGAGGGGCACCTTTTGGCCGTCTTCCTGGAGGCGCCGGTGCAGTTTC
CCTTCATCGCGCTCGCCGTCTCCGGGGGGCACTCGCACCTGTACCGGGTCGACGGGATCGGGCGCTATCAGACCCTGGGA
CAGACGGTGGATGACGCCGCCGGCGAGGCCTTCGATAAGGTAGCGAAGCTGATCGGGCTCCCTTACCCGGGGGGCGTGGC
CATCGACCGGCTGGCCGTGTCGGGCGATCCGCGGGCGATCAAGTTCCCGCGCCCGCTTTTGCACGATGGGACCTTCAACT
TCAGCTTCTCCGGCTTGAAGACTGCGGTGTTGACCCATGTCGGCAAGCACCCGGAGGCTAAGGAAGCGGGGATCAACGAC
CTCGCCGCCTCGTTCCAGGCGGCGGTCTGCGAGGTGCTCACCAAGAAGACGGCGGCCGCCATCGCCGCCACAGGGATAAA
AAGGCTGGTCGTGGCCGGCGGTGTCGCCTGCAACAGCGCGCTGCGCCGCTCCATGGGCGAGTATGCCGCGGCGAACGGGG
TGGAGCTTTCCATTCCCTCGCCCCCCCTTTGCGCAGACAACGCCGCGATGATAGCGGTCCCCGGCGACTACTATCTGGGC
CTCGGGATGAAGAGCGGTTTCGATCTCGACGCGCTTCCGGTGTGGCCCCTGGACAAGCTGGCCGCACGGCTGAAGGAGCA
TTGCTGA

Upstream 100 bases:

>100_bases
AGCGAAGCGAGCTCGCGGAGCTTGCCGCGAACCTGCTCTAACCCTACCGGCTCACACCGGCAACACCTCACATCAGGAGA
ACAAAGGGGGGGCACGTCCA

Downstream 100 bases:

>100_bases
TGGAGAAGATCCGCGCCAAGAAGGAGTTCGGCCAGAATTTCCTGGTCGACGACAGCGTACTGACCCGCATCGTCGCCTGC
GTCGCCCCCACGAAAGACGA

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease [H]

Number of amino acids: Translated: 348; Mature: 347

Protein sequence:

>348_residues
MPSLFFMLVLALESSCDETAAAVVKDGRTVLSSIVASQISVHAEYGGVVPEIASRKHLESVSFVVEQALAEAGVGLDRIE
GIAVTQGPGLAGALLVGISVAKGLAFGRSLPLVGVNHIEGHLLAVFLEAPVQFPFIALAVSGGHSHLYRVDGIGRYQTLG
QTVDDAAGEAFDKVAKLIGLPYPGGVAIDRLAVSGDPRAIKFPRPLLHDGTFNFSFSGLKTAVLTHVGKHPEAKEAGIND
LAASFQAAVCEVLTKKTAAAIAATGIKRLVVAGGVACNSALRRSMGEYAAANGVELSIPSPPLCADNAAMIAVPGDYYLG
LGMKSGFDLDALPVWPLDKLAARLKEHC

Sequences:

>Translated_348_residues
MPSLFFMLVLALESSCDETAAAVVKDGRTVLSSIVASQISVHAEYGGVVPEIASRKHLESVSFVVEQALAEAGVGLDRIE
GIAVTQGPGLAGALLVGISVAKGLAFGRSLPLVGVNHIEGHLLAVFLEAPVQFPFIALAVSGGHSHLYRVDGIGRYQTLG
QTVDDAAGEAFDKVAKLIGLPYPGGVAIDRLAVSGDPRAIKFPRPLLHDGTFNFSFSGLKTAVLTHVGKHPEAKEAGIND
LAASFQAAVCEVLTKKTAAAIAATGIKRLVVAGGVACNSALRRSMGEYAAANGVELSIPSPPLCADNAAMIAVPGDYYLG
LGMKSGFDLDALPVWPLDKLAARLKEHC
>Mature_347_residues
PSLFFMLVLALESSCDETAAAVVKDGRTVLSSIVASQISVHAEYGGVVPEIASRKHLESVSFVVEQALAEAGVGLDRIEG
IAVTQGPGLAGALLVGISVAKGLAFGRSLPLVGVNHIEGHLLAVFLEAPVQFPFIALAVSGGHSHLYRVDGIGRYQTLGQ
TVDDAAGEAFDKVAKLIGLPYPGGVAIDRLAVSGDPRAIKFPRPLLHDGTFNFSFSGLKTAVLTHVGKHPEAKEAGINDL
AASFQAAVCEVLTKKTAAAIAATGIKRLVVAGGVACNSALRRSMGEYAAANGVELSIPSPPLCADNAAMIAVPGDYYLGL
GMKSGFDLDALPVWPLDKLAARLKEHC

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family [H]

Homologues:

Organism=Homo sapiens, GI116812636, Length=359, Percent_Identity=34.5403899721448, Blast_Score=176, Evalue=2e-44,
Organism=Homo sapiens, GI8923380, Length=310, Percent_Identity=29.6774193548387, Blast_Score=115, Evalue=5e-26,
Organism=Escherichia coli, GI1789445, Length=337, Percent_Identity=44.5103857566766, Blast_Score=281, Evalue=5e-77,
Organism=Caenorhabditis elegans, GI17557464, Length=326, Percent_Identity=31.5950920245399, Blast_Score=151, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI71995670, Length=329, Percent_Identity=30.6990881458967, Blast_Score=125, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6320099, Length=371, Percent_Identity=30.4582210242588, Blast_Score=139, Evalue=6e-34,
Organism=Saccharomyces cerevisiae, GI6322891, Length=316, Percent_Identity=28.1645569620253, Blast_Score=95, Evalue=2e-20,
Organism=Drosophila melanogaster, GI20129063, Length=334, Percent_Identity=34.7305389221557, Blast_Score=180, Evalue=1e-45,
Organism=Drosophila melanogaster, GI21357207, Length=333, Percent_Identity=31.5315315315315, Blast_Score=132, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017861 [H]

Pfam domain/function: PF00814 Peptidase_M22 [H]

EC number: =3.4.24.57 [H]

Molecular weight: Translated: 36040; Mature: 35909

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSLFFMLVLALESSCDETAAAVVKDGRTVLSSIVASQISVHAEYGGVVPEIASRKHLES
CCHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
VSFVVEQALAEAGVGLDRIEGIAVTQGPGLAGALLVGISVAKGLAFGRSLPLVGVNHIEG
HHHHHHHHHHHHCCCHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCH
HLLAVFLEAPVQFPFIALAVSGGHSHLYRVDGIGRYQTLGQTVDDAAGEAFDKVAKLIGL
HEEEEEECCCCCCCEEEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
PYPGGVAIDRLAVSGDPRAIKFPRPLLHDGTFNFSFSGLKTAVLTHVGKHPEAKEAGIND
CCCCCCEEEEEEECCCCCEEECCCCHHCCCCCCEEHHHHHHHHHHHHCCCCCHHHCCHHH
LAASFQAAVCEVLTKKTAAAIAATGIKRLVVAGGVACNSALRRSMGEYAAANGVELSIPS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEECCC
PPLCADNAAMIAVPGDYYLGLGMKSGFDLDALPVWPLDKLAARLKEHC
CCCCCCCCEEEEECCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
PSLFFMLVLALESSCDETAAAVVKDGRTVLSSIVASQISVHAEYGGVVPEIASRKHLES
CHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
VSFVVEQALAEAGVGLDRIEGIAVTQGPGLAGALLVGISVAKGLAFGRSLPLVGVNHIEG
HHHHHHHHHHHHCCCHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCH
HLLAVFLEAPVQFPFIALAVSGGHSHLYRVDGIGRYQTLGQTVDDAAGEAFDKVAKLIGL
HEEEEEECCCCCCCEEEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
PYPGGVAIDRLAVSGDPRAIKFPRPLLHDGTFNFSFSGLKTAVLTHVGKHPEAKEAGIND
CCCCCCEEEEEEECCCCCEEECCCCHHCCCCCCEEHHHHHHHHHHHHCCCCCHHHCCHHH
LAASFQAAVCEVLTKKTAAAIAATGIKRLVVAGGVACNSALRRSMGEYAAANGVELSIPS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEECCC
PPLCADNAAMIAVPGDYYLGLGMKSGFDLDALPVWPLDKLAARLKEHC
CCCCCCCCEEEEECCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA