Click here to switch to the map view.

The map label for this gene is xerD [H]

Identifier: 197118261

GI number: 197118261

Start: 2173198

End: 2174076

Strand: Direct

Name: xerD [H]

Synonym: Gbem_1878

Alternate gene names: 197118261

Gene position: 2173198-2174076 (Clockwise)

Preceding gene: 197118260

Following gene: 197118262

Centisome position: 47.09

GC content: 62.91

Gene sequence:

>879_bases
GTGGACCGCTACCTCGATCTTTTTCTGAACTACCTCCTGGTGGAGAAGGGGGCGGCGGCGAACACGGTCTCCGCGTACAG
CCGCGACCTGAACCGTTATCTCCTCTTTCTGGGCGAGCGGGAGCCGGACGGCATCCGCCCGAGCGACGTCACCGGATTCC
TGGCCAAGCTGAAGGGGGAGGGGATAGCCCCCAGGAGCCGTGCCCGGGCTCTTTCCGCCCTGAGGATGCTGCATCGTTTC
CTGCTGCGGGAGGGGTATAGCGAGCTGAACCCGACCGCCATCATAGAGGCCCCCAAAGGGGTGCGGAAGCTGCCGGCGGT
CCTTTCCGGACGCGAGGTCGAGGCGCTTTTGAGCTCACCGCTCGACACCGGCGCCCAGGAGCTGCGGGACAAGGCGATGC
TGGAGCTTTTATACGCCACCGGGCTGCGCGTCTCCGAACTGGTGGGGTTGAAGCTTAGCGAGGTGAACCTTTCCGCCGGC
TATCTGATGACCATCGGCAAGGGGGACAAAGAGAGGCTGGTGCCGATGGGCGAGAGCGCCTGCCACGCCACCGGGGTCTA
TCTGCAGCAGGCGCGCGGCGAGCTGTTGAAGGAGAAGGCGAGTACGCTTCTTTTTCTGAGCCGGCTGGGCGGGGGGATGA
GTCGCCAGGCCTTTTGGAACATCATCAAGAAAAGGGCGTTGCAGGCCGGGGTGAGGACGAGCATATCGCCGCACACCCTG
CGTCACTCCTTTGCCACGCATCTTTTGGAGAACGGCGCCGATTTAAGGAGCGTGCAGATCATGTTGGGTCACGCCGACCT
TTCCTCCACCCAGATCTACACCCACGTGACGCGAGAGAGGATGAAAAAGCTGCACGCCGATTTTCACCCCAGGGGATAG

Upstream 100 bases:

>100_bases
CCGACGTCTTCTACGTGAAGGACATCTTCGGGCAGAAGATCATGAACCCCGGCAAGCTTGAGGAGATCCGCAAGGAGCTC
CTCGACGCAGTCGACGGCTA

Downstream 100 bases:

>100_bases
TGTCCATGAGGTCCATGGGGTCCATAGAGTCCATTGGGTCCACAAAAGGGTAGGGTAAGACCAAAAGCAAACCACCAAAC
CAAAGCAGCAAAAAGGAAAG

Product: integrase/recombinase XerD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MDRYLDLFLNYLLVEKGAAANTVSAYSRDLNRYLLFLGEREPDGIRPSDVTGFLAKLKGEGIAPRSRARALSALRMLHRF
LLREGYSELNPTAIIEAPKGVRKLPAVLSGREVEALLSSPLDTGAQELRDKAMLELLYATGLRVSELVGLKLSEVNLSAG
YLMTIGKGDKERLVPMGESACHATGVYLQQARGELLKEKASTLLFLSRLGGGMSRQAFWNIIKKRALQAGVRTSISPHTL
RHSFATHLLENGADLRSVQIMLGHADLSSTQIYTHVTRERMKKLHADFHPRG

Sequences:

>Translated_292_residues
MDRYLDLFLNYLLVEKGAAANTVSAYSRDLNRYLLFLGEREPDGIRPSDVTGFLAKLKGEGIAPRSRARALSALRMLHRF
LLREGYSELNPTAIIEAPKGVRKLPAVLSGREVEALLSSPLDTGAQELRDKAMLELLYATGLRVSELVGLKLSEVNLSAG
YLMTIGKGDKERLVPMGESACHATGVYLQQARGELLKEKASTLLFLSRLGGGMSRQAFWNIIKKRALQAGVRTSISPHTL
RHSFATHLLENGADLRSVQIMLGHADLSSTQIYTHVTRERMKKLHADFHPRG
>Mature_292_residues
MDRYLDLFLNYLLVEKGAAANTVSAYSRDLNRYLLFLGEREPDGIRPSDVTGFLAKLKGEGIAPRSRARALSALRMLHRF
LLREGYSELNPTAIIEAPKGVRKLPAVLSGREVEALLSSPLDTGAQELRDKAMLELLYATGLRVSELVGLKLSEVNLSAG
YLMTIGKGDKERLVPMGESACHATGVYLQQARGELLKEKASTLLFLSRLGGGMSRQAFWNIIKKRALQAGVRTSISPHTL
RHSFATHLLENGADLRSVQIMLGHADLSSTQIYTHVTRERMKKLHADFHPRG

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=294, Percent_Identity=48.2993197278912, Blast_Score=257, Evalue=7e-70,
Organism=Escherichia coli, GI1790244, Length=288, Percent_Identity=36.1111111111111, Blast_Score=167, Evalue=6e-43,
Organism=Escherichia coli, GI1790768, Length=174, Percent_Identity=32.183908045977, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1790767, Length=178, Percent_Identity=32.5842696629214, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 32306; Mature: 32306

Theoretical pI: Translated: 10.28; Mature: 10.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRYLDLFLNYLLVEKGAAANTVSAYSRDLNRYLLFLGEREPDGIRPSDVTGFLAKLKGE
CCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEEEECCCCCCCCCCHHHHHHHHHCCC
GIAPRSRARALSALRMLHRFLLREGYSELNPTAIIEAPKGVRKLPAVLSGREVEALLSSP
CCCCHHHHHHHHHHHHHHHHHHHHCHHHCCCCEEEECCCCHHHHHHHHCCCHHHHHHCCC
LDTGAQELRDKAMLELLYATGLRVSELVGLKLSEVNLSAGYLMTIGKGDKERLVPMGESA
CCCCHHHHHHHHHHHHHHHCCCHHHHHHCCEEEEEECCCCEEEEECCCCHHHCCCCCCHH
CHATGVYLQQARGELLKEKASTLLFLSRLGGGMSRQAFWNIIKKRALQAGVRTSISPHTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHH
RHSFATHLLENGADLRSVQIMLGHADLSSTQIYTHVTRERMKKLHADFHPRG
HHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MDRYLDLFLNYLLVEKGAAANTVSAYSRDLNRYLLFLGEREPDGIRPSDVTGFLAKLKGE
CCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEEEECCCCCCCCCCHHHHHHHHHCCC
GIAPRSRARALSALRMLHRFLLREGYSELNPTAIIEAPKGVRKLPAVLSGREVEALLSSP
CCCCHHHHHHHHHHHHHHHHHHHHCHHHCCCCEEEECCCCHHHHHHHHCCCHHHHHHCCC
LDTGAQELRDKAMLELLYATGLRVSELVGLKLSEVNLSAGYLMTIGKGDKERLVPMGESA
CCCCHHHHHHHHHHHHHHHCCCHHHHHHCCEEEEEECCCCEEEEECCCCHHHCCCCCCHH
CHATGVYLQQARGELLKEKASTLLFLSRLGGGMSRQAFWNIIKKRALQAGVRTSISPHTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHH
RHSFATHLLENGADLRSVQIMLGHADLSSTQIYTHVTRERMKKLHADFHPRG
HHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]