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The map label for this gene is yqiR [H]

Identifier: 197117825

GI number: 197117825

Start: 1660552

End: 1662330

Strand: Direct

Name: yqiR [H]

Synonym: Gbem_1438

Alternate gene names: 197117825

Gene position: 1660552-1662330 (Clockwise)

Preceding gene: 197117824

Following gene: 197117826

Centisome position: 35.98

GC content: 63.24

Gene sequence:

>1779_bases
ATGGTGCAGGTCGCTGACATAACGGGGATGGAAGGGACTACCGGCTGCGGTGACGCTTCGGGCATCGTGAGGCTGGACGC
CGATCTCGGCATCACCTACCTCGACGCGGCCGCCGCTGACCTGATAGGGATCCCCGCGGAGAGCCTTTTGGGGTGCGGGC
TCGACGAGGTGGCGGATCTCTCCGAGCTCAGCACCCTGATGAGAAGCGGCACCGTCTTCAACAATCAGGTGCTGCAGGTC
GGCAAGAGGCGTCTGGTCTGCGACTTTCTCCCGACCATGGAGTCGGAGCAGCTGGTGGGGGGGATTTTGTCCGTCCTGCG
GCTCCTTCCGGAACAACTCCCCGATCCCTCCATCGATTTGAGAGCCCTGTTGCAGTCGGGTAGCGCCTCCCTCGATCTCA
ACTACGACGGCATCGTCATCGTGGACCGGGAAGGGGTGGTGGTCATGGTCAACCAGGCCTTCGCCGACATCCTCGACACC
ACCCCCAACGCCATCATCGGCAAGCACGTCAGCGATGCCTACCCCAATTCCCAGTCCTCGAAGCTGCCGGCGGTCATGGA
AACCGCCACCCCCCAGATCGGCATCACCCATTACCTGAACGGCAAGCAGGTCTACGCCTCGCTCTATCCGATCGTCAAGG
ACGGCCAGGTGATCGGCGGGGTCGGCAAAATCCTGTTCAAGGACATCCGCGAGATCACGCTGATCGCCAACCGGCTGCAG
GGCGCCTCCGAGACGCGCGCGGCGGCCGGGAACGTGGCGCGCAAGGAATCGATGTCGCGCTACGACGTGAACAGCATCGT
CGGGCAGAGCAAGCAGATGCAGGACCTGAAAGAGTCCCTGCTGCGGGTGGCTTCCAAGAACTCGAACATCCTCCTCCTGG
GGGAGAGCGGGACCGGGAAAGAGCTTTTCGCCCACGCCATCCACGCCGCCAGCAACCGCCGCTACGCCCAGTTCGTCAAG
GTCAACTGCGCCGCCATTCCGGAACATCTGCTGGAAAGCGAGCTCTTCGGCTATGCCGAGGGAGCCTTCACTGGGGCGAG
GAAAGGGGGGCAGCTGGGGAAATTCGAGCAGGCGCACCTGGGGACCATCTTCCTGGACGAGATCGGCGACATGCCGCTGT
ACATGCAGGCGAAGATGCTGCGGGTCCTGCAGGAGAGGGAGCTGACACCTTTGGGGAGCAACGCGCCGAAAACGGTCGAC
GTGAGGGTGGTCGCCGCCACCAACAGCAACCTCGAGGCCTTGGTGCGGGAGGGGAAGTTCCGGCAGGACCTCTACTATCG
CCTCAAGGTGGTGACGCTCTGCATCCCCGCGCTCAGGGAGCGCAAGGAGGACATCCGCGCCCTCAGCATAAATTTCATCC
AGCAGTTCAACGAGGAGTTCGGGCTGGAGGTCCAGGCGCTGAGCCTGGAGGCCCGCGACGTGGTCATGCACTACGACTGG
CCGGGGAACGTGAGGGAGCTGCGCAACGTGATCGAGAGCGCCTTCAACGTGGTGACCGGTCCGCTCATCCTCAAGGAGCA
CCTCCCGGAACAGCTCTCCAGGATGATCCAGGACGGCAGCTCCGGCATCCCGCACGACATCGGCCCCTACCTGCGCGCAA
GGCTCGGGAGCAAGCCGCTTCCGGCCATCGTCGAGGAGTTCGAGAAGCTGCTGGTCGAGGCCGCCATCGAGTTTTGCAAC
GGCAACAAGCTGCAGGCCGCCGATCTGCTCGGCATCTCTCGGCAGTGGCTGTACAAGAAGCTACAAAAGAAGCATAACGA
CGACTCTTCCGGCCACTGA

Upstream 100 bases:

>100_bases
GGTGGGAGGGAGGCAGAGAAGGGGGACAGGCACTTGCGGAGCCAGTCCCCCAGGGCGGAGCCAGTCACCTAGGTCATGAA
GGAAGAAAGAGAAGGCGCTT

Downstream 100 bases:

>100_bases
GTCCCGGCTTCATTCGCCCCCGGGCCGCTCCCTCCTGTCAGCAAATCAACCCGTTTCCCAGCTCTCCCCCTCCCGCAAGG
GGAGGGGGAAACCTAACACC

Product: sigma-54-dependent sensor transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 592; Mature: 592

Protein sequence:

>592_residues
MVQVADITGMEGTTGCGDASGIVRLDADLGITYLDAAAADLIGIPAESLLGCGLDEVADLSELSTLMRSGTVFNNQVLQV
GKRRLVCDFLPTMESEQLVGGILSVLRLLPEQLPDPSIDLRALLQSGSASLDLNYDGIVIVDREGVVVMVNQAFADILDT
TPNAIIGKHVSDAYPNSQSSKLPAVMETATPQIGITHYLNGKQVYASLYPIVKDGQVIGGVGKILFKDIREITLIANRLQ
GASETRAAAGNVARKESMSRYDVNSIVGQSKQMQDLKESLLRVASKNSNILLLGESGTGKELFAHAIHAASNRRYAQFVK
VNCAAIPEHLLESELFGYAEGAFTGARKGGQLGKFEQAHLGTIFLDEIGDMPLYMQAKMLRVLQERELTPLGSNAPKTVD
VRVVAATNSNLEALVREGKFRQDLYYRLKVVTLCIPALRERKEDIRALSINFIQQFNEEFGLEVQALSLEARDVVMHYDW
PGNVRELRNVIESAFNVVTGPLILKEHLPEQLSRMIQDGSSGIPHDIGPYLRARLGSKPLPAIVEEFEKLLVEAAIEFCN
GNKLQAADLLGISRQWLYKKLQKKHNDDSSGH

Sequences:

>Translated_592_residues
MVQVADITGMEGTTGCGDASGIVRLDADLGITYLDAAAADLIGIPAESLLGCGLDEVADLSELSTLMRSGTVFNNQVLQV
GKRRLVCDFLPTMESEQLVGGILSVLRLLPEQLPDPSIDLRALLQSGSASLDLNYDGIVIVDREGVVVMVNQAFADILDT
TPNAIIGKHVSDAYPNSQSSKLPAVMETATPQIGITHYLNGKQVYASLYPIVKDGQVIGGVGKILFKDIREITLIANRLQ
GASETRAAAGNVARKESMSRYDVNSIVGQSKQMQDLKESLLRVASKNSNILLLGESGTGKELFAHAIHAASNRRYAQFVK
VNCAAIPEHLLESELFGYAEGAFTGARKGGQLGKFEQAHLGTIFLDEIGDMPLYMQAKMLRVLQERELTPLGSNAPKTVD
VRVVAATNSNLEALVREGKFRQDLYYRLKVVTLCIPALRERKEDIRALSINFIQQFNEEFGLEVQALSLEARDVVMHYDW
PGNVRELRNVIESAFNVVTGPLILKEHLPEQLSRMIQDGSSGIPHDIGPYLRARLGSKPLPAIVEEFEKLLVEAAIEFCN
GNKLQAADLLGISRQWLYKKLQKKHNDDSSGH
>Mature_592_residues
MVQVADITGMEGTTGCGDASGIVRLDADLGITYLDAAAADLIGIPAESLLGCGLDEVADLSELSTLMRSGTVFNNQVLQV
GKRRLVCDFLPTMESEQLVGGILSVLRLLPEQLPDPSIDLRALLQSGSASLDLNYDGIVIVDREGVVVMVNQAFADILDT
TPNAIIGKHVSDAYPNSQSSKLPAVMETATPQIGITHYLNGKQVYASLYPIVKDGQVIGGVGKILFKDIREITLIANRLQ
GASETRAAAGNVARKESMSRYDVNSIVGQSKQMQDLKESLLRVASKNSNILLLGESGTGKELFAHAIHAASNRRYAQFVK
VNCAAIPEHLLESELFGYAEGAFTGARKGGQLGKFEQAHLGTIFLDEIGDMPLYMQAKMLRVLQERELTPLGSNAPKTVD
VRVVAATNSNLEALVREGKFRQDLYYRLKVVTLCIPALRERKEDIRALSINFIQQFNEEFGLEVQALSLEARDVVMHYDW
PGNVRELRNVIESAFNVVTGPLILKEHLPEQLSRMIQDGSSGIPHDIGPYLRARLGSKPLPAIVEEFEKLLVEAAIEFCN
GNKLQAADLLGISRQWLYKKLQKKHNDDSSGH

Specific function: Member Of The Two-Component Regulatory System Atos/Atoc Involved In The Transcriptional Regulation Of The Ato Genes For Acetoacetate Metabolism. Also An Inhibitor Of Polyamine Biosynthesis. [C]

COG id: COG3829

COG function: function code KT; Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=399, Percent_Identity=39.8496240601504, Blast_Score=273, Evalue=2e-74,
Organism=Escherichia coli, GI1789233, Length=458, Percent_Identity=37.117903930131, Blast_Score=266, Evalue=3e-72,
Organism=Escherichia coli, GI1790437, Length=322, Percent_Identity=45.6521739130435, Blast_Score=263, Evalue=2e-71,
Organism=Escherichia coli, GI1786524, Length=344, Percent_Identity=40.406976744186, Blast_Score=250, Evalue=2e-67,
Organism=Escherichia coli, GI1790299, Length=330, Percent_Identity=41.8181818181818, Blast_Score=244, Evalue=1e-65,
Organism=Escherichia coli, GI1788905, Length=323, Percent_Identity=42.7244582043344, Blast_Score=235, Evalue=6e-63,
Organism=Escherichia coli, GI87082117, Length=259, Percent_Identity=49.034749034749, Blast_Score=234, Evalue=2e-62,
Organism=Escherichia coli, GI1789087, Length=267, Percent_Identity=45.3183520599251, Blast_Score=222, Evalue=6e-59,
Organism=Escherichia coli, GI87082152, Length=231, Percent_Identity=48.4848484848485, Blast_Score=204, Evalue=2e-53,
Organism=Escherichia coli, GI87081872, Length=347, Percent_Identity=36.5994236311239, Blast_Score=197, Evalue=1e-51,
Organism=Escherichia coli, GI1787583, Length=306, Percent_Identity=36.9281045751634, Blast_Score=187, Evalue=2e-48,
Organism=Escherichia coli, GI1789828, Length=323, Percent_Identity=30.9597523219814, Blast_Score=132, Evalue=6e-32,
Organism=Escherichia coli, GI87081858, Length=459, Percent_Identity=28.5403050108932, Blast_Score=120, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR002197
- InterPro:   IPR016040
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00989 PAS; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 64675; Mature: 64675

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS50112 PAS ; PS00675 SIGMA54_INTERACT_1 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVQVADITGMEGTTGCGDASGIVRLDADLGITYLDAAAADLIGIPAESLLGCGLDEVADL
CEEEECCCCCCCCCCCCCCCCEEEEECCCCEEHHHHHHHHHHCCCHHHHHCCCCHHHHHH
SELSTLMRSGTVFNNQVLQVGKRRLVCDFLPTMESEQLVGGILSVLRLLPEQLPDPSIDL
HHHHHHHHCCCCCHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHH
RALLQSGSASLDLNYDGIVIVDREGVVVMVNQAFADILDTTPNAIIGKHVSDAYPNSQSS
HHHHHCCCCEEEECCCCEEEECCCCEEEEEHHHHHHHHHCCCCHHHHCCHHCCCCCCCCC
KLPAVMETATPQIGITHYLNGKQVYASLYPIVKDGQVIGGVGKILFKDIREITLIANRLQ
CCCHHHHHCCCCCCEEEEECCHHHHHHHCCHHCCCCEEHHHHHHHHHHHHHHHHHHHHHC
GASETRAAAGNVARKESMSRYDVNSIVGQSKQMQDLKESLLRVASKNSNILLLGESGTGK
CCHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCH
ELFAHAIHAASNRRYAQFVKVNCAAIPEHLLESELFGYAEGAFTGARKGGQLGKFEQAHL
HHHHHHHHHHCCCCEEHHEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHC
GTIFLDEIGDMPLYMQAKMLRVLQERELTPLGSNAPKTVDVRVVAATNSNLEALVREGKF
CEEEHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEECCCCHHHHHHCCCH
RQDLYYRLKVVTLCIPALRERKEDIRALSINFIQQFNEEFGLEVQALSLEARDVVMHYDW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEEEEEEEECC
PGNVRELRNVIESAFNVVTGPLILKEHLPEQLSRMIQDGSSGIPHDIGPYLRARLGSKPL
CCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCC
PAIVEEFEKLLVEAAIEFCNGNKLQAADLLGISRQWLYKKLQKKHNDDSSGH
HHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MVQVADITGMEGTTGCGDASGIVRLDADLGITYLDAAAADLIGIPAESLLGCGLDEVADL
CEEEECCCCCCCCCCCCCCCCEEEEECCCCEEHHHHHHHHHHCCCHHHHHCCCCHHHHHH
SELSTLMRSGTVFNNQVLQVGKRRLVCDFLPTMESEQLVGGILSVLRLLPEQLPDPSIDL
HHHHHHHHCCCCCHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHH
RALLQSGSASLDLNYDGIVIVDREGVVVMVNQAFADILDTTPNAIIGKHVSDAYPNSQSS
HHHHHCCCCEEEECCCCEEEECCCCEEEEEHHHHHHHHHCCCCHHHHCCHHCCCCCCCCC
KLPAVMETATPQIGITHYLNGKQVYASLYPIVKDGQVIGGVGKILFKDIREITLIANRLQ
CCCHHHHHCCCCCCEEEEECCHHHHHHHCCHHCCCCEEHHHHHHHHHHHHHHHHHHHHHC
GASETRAAAGNVARKESMSRYDVNSIVGQSKQMQDLKESLLRVASKNSNILLLGESGTGK
CCHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCH
ELFAHAIHAASNRRYAQFVKVNCAAIPEHLLESELFGYAEGAFTGARKGGQLGKFEQAHL
HHHHHHHHHHCCCCEEHHEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHC
GTIFLDEIGDMPLYMQAKMLRVLQERELTPLGSNAPKTVDVRVVAATNSNLEALVREGKF
CEEEHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEECCCCHHHHHHCCCH
RQDLYYRLKVVTLCIPALRERKEDIRALSINFIQQFNEEFGLEVQALSLEARDVVMHYDW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEEEEEEEECC
PGNVRELRNVIESAFNVVTGPLILKEHLPEQLSRMIQDGSSGIPHDIGPYLRARLGSKPL
CCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCC
PAIVEEFEKLLVEAAIEFCNGNKLQAADLLGISRQWLYKKLQKKHNDDSSGH
HHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]