Click here to switch to the map view.

The map label for this gene is kdgR [H]

Identifier: 197117795

GI number: 197117795

Start: 1620952

End: 1621725

Strand: Direct

Name: kdgR [H]

Synonym: Gbem_1407

Alternate gene names: 197117795

Gene position: 1620952-1621725 (Clockwise)

Preceding gene: 197117788

Following gene: 197117796

Centisome position: 35.12

GC content: 60.98

Gene sequence:

>774_bases
ATGAAAACCGGTAAGAAAAACACGAACTACAACCGAAGCGTCTGCCGCGCGCTGGACGTTCTGGAGCAGTTCCTCCTGGA
GGACCACGAGATCGGTCTGACGGAGCTGAGCCGGCGCCTCAAGCTGCCTAAGAACAACATCTTCCGTTTGCTGGCGACAC
TGCAGCTGCGCAACTACGTCTCCAAGGACCCGGTGACGGAGCGGTATCAACTGGGGTTCATGACGGTGGAACTGGCCCAG
AAGGCCCTCCAGCAGCGGGGACTGGGAGGAGCACGGACGGTCATGGAGCGGTTGGTGCGCGCGTGCAACGAGACCACCTG
CGTCTCGATCATGTCTGACTACAGCGTGATAAATCTCGACTCGGTCGAGTGTGACCACAACCTGCGGGTCATGCCCGCCC
TTGGCGTGCAGCTTCCCGCCTACTGCACCGCGCCGGGAAAGTCATTAATGGCGCATTTTGCCGATGAGGCGATCGCCAAG
TACACCTCGAACAACAAGTTCGAAAAGCACACGCCGCACACCATCACCGATGCGGAGAGCTGGAAGGACCAACTGCGGGA
AATTGCCCGGCAGGGGTACGCAGTGGAGTCGGAGGAATTGAACCTGGGAGTGACCAGCGTCGGCGCCCCCATCCGCGACT
ACACCTCGCGCGTCATCGGAGCGGTGAGCATGCTCGGCCCCTCGCAGCGCTTTCATCGCGAGCGGATAGAGCAGGAGCTT
GTGCCGCTTTTGAAACGGGGGGCAGCGGATATCTCCGCCGCGCTCGGCTATTGA

Upstream 100 bases:

>100_bases
GATTTGACATGGTGTTTTATTTATGGTAATTGGGTACTCCAATACTATTATGGGGCGCAGGAAGCTGCCAGCCCGGGAGG
AAGCCCAGAGGAAGCGGATC

Downstream 100 bases:

>100_bases
AGCGATGCGGGGCTAGGGCGGATAGGGCGGATAGGGCGGATAACGGGAATAAATTACAGGGGATGAGCGACATGAAATTC
AACGGAACCGAATCCTACAT

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MKTGKKNTNYNRSVCRALDVLEQFLLEDHEIGLTELSRRLKLPKNNIFRLLATLQLRNYVSKDPVTERYQLGFMTVELAQ
KALQQRGLGGARTVMERLVRACNETTCVSIMSDYSVINLDSVECDHNLRVMPALGVQLPAYCTAPGKSLMAHFADEAIAK
YTSNNKFEKHTPHTITDAESWKDQLREIARQGYAVESEELNLGVTSVGAPIRDYTSRVIGAVSMLGPSQRFHRERIEQEL
VPLLKRGAADISAALGY

Sequences:

>Translated_257_residues
MKTGKKNTNYNRSVCRALDVLEQFLLEDHEIGLTELSRRLKLPKNNIFRLLATLQLRNYVSKDPVTERYQLGFMTVELAQ
KALQQRGLGGARTVMERLVRACNETTCVSIMSDYSVINLDSVECDHNLRVMPALGVQLPAYCTAPGKSLMAHFADEAIAK
YTSNNKFEKHTPHTITDAESWKDQLREIARQGYAVESEELNLGVTSVGAPIRDYTSRVIGAVSMLGPSQRFHRERIEQEL
VPLLKRGAADISAALGY
>Mature_257_residues
MKTGKKNTNYNRSVCRALDVLEQFLLEDHEIGLTELSRRLKLPKNNIFRLLATLQLRNYVSKDPVTERYQLGFMTVELAQ
KALQQRGLGGARTVMERLVRACNETTCVSIMSDYSVINLDSVECDHNLRVMPALGVQLPAYCTAPGKSLMAHFADEAIAK
YTSNNKFEKHTPHTITDAESWKDQLREIARQGYAVESEELNLGVTSVGAPIRDYTSRVIGAVSMLGPSQRFHRERIEQEL
VPLLKRGAADISAALGY

Specific function: Transcriptional repressor of genes involved in pectinolysis and in pectinase secretion. Controls all the genes involved in pectin catabolism, including the pel genes encoding pectate lyases, kdgT which encodes the 2-keto-3-deoxygluconate transport system

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1788131, Length=246, Percent_Identity=32.520325203252, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI87082359, Length=252, Percent_Identity=25.7936507936508, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1786468, Length=251, Percent_Identity=29.0836653386454, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1786715, Length=242, Percent_Identity=27.2727272727273, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1789999, Length=263, Percent_Identity=30.4182509505703, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1790752, Length=251, Percent_Identity=25.4980079681275, Blast_Score=75, Evalue=4e-15,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 28829; Mature: 28829

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTGKKNTNYNRSVCRALDVLEQFLLEDHEIGLTELSRRLKLPKNNIFRLLATLQLRNYV
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHH
SKDPVTERYQLGFMTVELAQKALQQRGLGGARTVMERLVRACNETTCVSIMSDYSVINLD
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCEEECC
SVECDHNLRVMPALGVQLPAYCTAPGKSLMAHFADEAIAKYTSNNKFEKHTPHTITDAES
CCCCCCCCEEECCCCCCCCCEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHH
WKDQLREIARQGYAVESEELNLGVTSVGAPIRDYTSRVIGAVSMLGPSQRFHRERIEQEL
HHHHHHHHHHCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
VPLLKRGAADISAALGY
HHHHHHCHHHHHHHCCC
>Mature Secondary Structure
MKTGKKNTNYNRSVCRALDVLEQFLLEDHEIGLTELSRRLKLPKNNIFRLLATLQLRNYV
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHH
SKDPVTERYQLGFMTVELAQKALQQRGLGGARTVMERLVRACNETTCVSIMSDYSVINLD
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCEEECC
SVECDHNLRVMPALGVQLPAYCTAPGKSLMAHFADEAIAKYTSNNKFEKHTPHTITDAES
CCCCCCCCEEECCCCCCCCCEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHH
WKDQLREIARQGYAVESEELNLGVTSVGAPIRDYTSRVIGAVSMLGPSQRFHRERIEQEL
HHHHHHHHHHCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
VPLLKRGAADISAALGY
HHHHHHCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1840643; 1545709 [H]