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The map label for this gene is merB [H]

Identifier: 197116719

GI number: 197116719

Start: 392292

End: 392921

Strand: Direct

Name: merB [H]

Synonym: Gbem_0319

Alternate gene names: 197116719

Gene position: 392292-392921 (Clockwise)

Preceding gene: 197116717

Following gene: 197116720

Centisome position: 8.5

GC content: 58.89

Gene sequence:

>630_bases
ATGGCAGGAGGCACTTTACACGATGTACTGGCTGGCTTGCACTGTGACCACCCACGGGTCTGGTTGTTCCTCCTCCGTGC
TCTGGCGAAGGGGCGGCCTGTTTCCCGCACCACTATAGCGAACGCTCTTAACAGTTCTCTCTCCGAGATTGAGGCGGCGT
TGGCGTCCTTTGCCGACACGGTGTACGACGAGAAAGGCGACGTGGTGGCCTGCGGGTTGTCGCTCATGCCTACGCCGCAT
TCCTTTACGGTCTGCGGCAATCAGCTTTACACCTGGTGTGCCCTGGATGCCCTCATGTATCCCGTGGCGCTGGAACAGGT
CGCACAGGTGGAATCGCATTGCCCGGTTACGGGCATCCCGGTTCGTATGACGGCAACTCCGACGGGGGTCGTCGATCCGT
CTCCGGCTGGAGTTAGCCTTTCGATGGTTGCACCTTCAGAGCAAGCCGGCTGCTGCAGCGTCCGTAACAGCTTTTGCAGT
GGGGTGCACTTCATAAGTTCCGCTGAAGCTGCAGCTTCGTGGCTGTCTCTGCATCCCGAAGCAAGCATAGTGTCGTTGGA
AGAAGCGTGGCAGATCGGACATGCAGTAATGCAGCAACGACTGTCGCATGGAGAGACGTCACGCCCTTGA

Upstream 100 bases:

>100_bases
GGTCCATTGGCCCGATGCTGCCTTTTCGGCGTTCGTGGTGTGAACAAGGCAATAAGGGAACTGAATGAATAATGGCAGCT
TTCCAGGAGGGGGAGGGACG

Downstream 100 bases:

>100_bases
TCTTACGCGGTCACTTTCCGGGGTAGTCGACAAGGCCCGGTGTCTGTACGAATGGGTGAGCGCTATGGGATTTGCCTTGG
TTAGACATACAAGCTAACGG

Product: alkylmercury lyase

Products: NA

Alternate protein names: Organomercurial lyase [H]

Number of amino acids: Translated: 209; Mature: 208

Protein sequence:

>209_residues
MAGGTLHDVLAGLHCDHPRVWLFLLRALAKGRPVSRTTIANALNSSLSEIEAALASFADTVYDEKGDVVACGLSLMPTPH
SFTVCGNQLYTWCALDALMYPVALEQVAQVESHCPVTGIPVRMTATPTGVVDPSPAGVSLSMVAPSEQAGCCSVRNSFCS
GVHFISSAEAAASWLSLHPEASIVSLEEAWQIGHAVMQQRLSHGETSRP

Sequences:

>Translated_209_residues
MAGGTLHDVLAGLHCDHPRVWLFLLRALAKGRPVSRTTIANALNSSLSEIEAALASFADTVYDEKGDVVACGLSLMPTPH
SFTVCGNQLYTWCALDALMYPVALEQVAQVESHCPVTGIPVRMTATPTGVVDPSPAGVSLSMVAPSEQAGCCSVRNSFCS
GVHFISSAEAAASWLSLHPEASIVSLEEAWQIGHAVMQQRLSHGETSRP
>Mature_208_residues
AGGTLHDVLAGLHCDHPRVWLFLLRALAKGRPVSRTTIANALNSSLSEIEAALASFADTVYDEKGDVVACGLSLMPTPHS
FTVCGNQLYTWCALDALMYPVALEQVAQVESHCPVTGIPVRMTATPTGVVDPSPAGVSLSMVAPSEQAGCCSVRNSFCSG
VHFISSAEAAASWLSLHPEASIVSLEEAWQIGHAVMQQRLSHGETSRP

Specific function: Cleaves the carbon-mercury bond of organomercurials such as phenylmercuric acetate. One product is Hg(2+), which is subsequently detoxified by the mercuric reductase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the merB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004927 [H]

Pfam domain/function: PF03243 MerB [H]

EC number: =4.99.1.2 [H]

Molecular weight: Translated: 22083; Mature: 21952

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGGTLHDVLAGLHCDHPRVWLFLLRALAKGRPVSRTTIANALNSSLSEIEAALASFADT
CCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VYDEKGDVVACGLSLMPTPHSFTVCGNQLYTWCALDALMYPVALEQVAQVESHCPVTGIP
HHCCCCCEEEECCEECCCCCCEEHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
VRMTATPTGVVDPSPAGVSLSMVAPSEQAGCCSVRNSFCSGVHFISSAEAAASWLSLHPE
EEEECCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ASIVSLEEAWQIGHAVMQQRLSHGETSRP
CCEEHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
AGGTLHDVLAGLHCDHPRVWLFLLRALAKGRPVSRTTIANALNSSLSEIEAALASFADT
CCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VYDEKGDVVACGLSLMPTPHSFTVCGNQLYTWCALDALMYPVALEQVAQVESHCPVTGIP
HHCCCCCEEEECCEECCCCCCEEHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
VRMTATPTGVVDPSPAGVSLSMVAPSEQAGCCSVRNSFCSGVHFISSAEAAASWLSLHPE
EEEECCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ASIVSLEEAWQIGHAVMQQRLSHGETSRP
CCEEHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1494353 [H]