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The map label for this gene is mqnC-2 [H]

Identifier: 197116634

GI number: 197116634

Start: 277885

End: 278961

Strand: Direct

Name: mqnC-2 [H]

Synonym: Gbem_0234

Alternate gene names: 197116634

Gene position: 277885-278961 (Clockwise)

Preceding gene: 197116633

Following gene: 197116635

Centisome position: 6.02

GC content: 64.53

Gene sequence:

>1077_bases
ATGACTTTTGCCACCATAGCGGAGAAGGTGCGGGCGGGCGGACGCATCACGGAGCCAGAGGCGCTCGTGCTTTTCGAGCA
CCCGGACCTCCTGGCGCTCGGAGAGCTGGCCCAGTCCGTCAACGAGCGGCGCAACGGGAAGAGGGTTTTCTTCAACGTCA
ACCGCCACATCAACCACACCAATATCTGCGTGAACCGTTGCCGCTTCTGCGCCTTCTTCCGCAAAGCCGGCGACCCAGGC
GCCTACCTGATGACTCTGGACGAGGTCCGCGGCCGTGCCGAAGAGGCGGTCAAGGAAGGGGCCACCGAGATCCACGTGGT
GGGAGGCCTCCACCCGGAGCTCCCCTTCGAGTTCTACTTGGAGCTCCTTGCCACCGTCAAGGCGGTCTCCCCGGCGCTGC
ACGTGAAAGCCTTCACCGCAGTGGAGATCGCTTATCTGGCTAAACTCTCCGGCCTTGGCATCCCGGCCACCCTGGAGAAG
CTGAAGGAGGCGGGGCTCGGCTCACTTCCCGGCGGCGGCGCCGAGATCTTCGCGCCGGAGATCCGCAACCAGCTTTGCCC
GGAAAAGATCAGCGGCGCGGCCTGGCTCTCCATCATGGAACAGGTGCACCAGGCGGGGCTCAAGTCGAACGCCACCATGC
TCTATGGGCATCTGGAGAGCGTGGCCGACCGGGTCGACCATATGCGGCAGCTGCGCGAGCTGCAGGATCGAACCGGCGGC
TTCCAGGTTTTCATCCCGCTCGCCTTCCAGCCTGAGCATTCGCAGTTGAAGATCGCCGGTTCCGGCACGAGCGGCGTGGA
CGACCTGCGCACCCTGGCCGTCGCCCGCATCTACCTGGACAACTTCGCCAACGTCAAGGCCTACTGGGTGATGCTGGGGG
AGAAGATAGCCCAGGTATCGCTATCCTTCGGCGTCAACGACCTGGACGGTACCGTGGTCGAGGAGCGGATCGGGCACGAG
GCGGGAGCGGACACCCCGCAGACCATGAGCCGCGACAACATCGTCACCATGATCAGGAAGGCCGGGCGCATCCCGGTGGA
GCGGGACACCCTCTACCAGGAACTGCGCGTCTATTGA

Upstream 100 bases:

>100_bases
GGTCGATTTCGTGGCCGGAAAGGTGCTGGACGCAGTGCAGGTGGAGCACACGCTCTTCAGGCGCTGGGGAAGCCGGCCGT
AAACGAAAAAGGAAAGAACC

Downstream 100 bases:

>100_bases
GAAGGGGACCGCGCCTGCGTCGGACCATTGCAATGAAGCCTGCGAAACCACGGAAGTAAGCCAATGTCGAAAATGTTCCA
CGCCATAATTGAAAAAGTCG

Product: dehypoxanthinylfutalosine cyclase

Products: NA

Alternate protein names: 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit 2 [H]

Number of amino acids: Translated: 358; Mature: 357

Protein sequence:

>358_residues
MTFATIAEKVRAGGRITEPEALVLFEHPDLLALGELAQSVNERRNGKRVFFNVNRHINHTNICVNRCRFCAFFRKAGDPG
AYLMTLDEVRGRAEEAVKEGATEIHVVGGLHPELPFEFYLELLATVKAVSPALHVKAFTAVEIAYLAKLSGLGIPATLEK
LKEAGLGSLPGGGAEIFAPEIRNQLCPEKISGAAWLSIMEQVHQAGLKSNATMLYGHLESVADRVDHMRQLRELQDRTGG
FQVFIPLAFQPEHSQLKIAGSGTSGVDDLRTLAVARIYLDNFANVKAYWVMLGEKIAQVSLSFGVNDLDGTVVEERIGHE
AGADTPQTMSRDNIVTMIRKAGRIPVERDTLYQELRVY

Sequences:

>Translated_358_residues
MTFATIAEKVRAGGRITEPEALVLFEHPDLLALGELAQSVNERRNGKRVFFNVNRHINHTNICVNRCRFCAFFRKAGDPG
AYLMTLDEVRGRAEEAVKEGATEIHVVGGLHPELPFEFYLELLATVKAVSPALHVKAFTAVEIAYLAKLSGLGIPATLEK
LKEAGLGSLPGGGAEIFAPEIRNQLCPEKISGAAWLSIMEQVHQAGLKSNATMLYGHLESVADRVDHMRQLRELQDRTGG
FQVFIPLAFQPEHSQLKIAGSGTSGVDDLRTLAVARIYLDNFANVKAYWVMLGEKIAQVSLSFGVNDLDGTVVEERIGHE
AGADTPQTMSRDNIVTMIRKAGRIPVERDTLYQELRVY
>Mature_357_residues
TFATIAEKVRAGGRITEPEALVLFEHPDLLALGELAQSVNERRNGKRVFFNVNRHINHTNICVNRCRFCAFFRKAGDPGA
YLMTLDEVRGRAEEAVKEGATEIHVVGGLHPELPFEFYLELLATVKAVSPALHVKAFTAVEIAYLAKLSGLGIPATLEKL
KEAGLGSLPGGGAEIFAPEIRNQLCPEKISGAAWLSIMEQVHQAGLKSNATMLYGHLESVADRVDHMRQLRELQDRTGGF
QVFIPLAFQPEHSQLKIAGSGTSGVDDLRTLAVARIYLDNFANVKAYWVMLGEKIAQVSLSFGVNDLDGTVVEERIGHEA
GADTPQTMSRDNIVTMIRKAGRIPVERDTLYQELRVY

Specific function: Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) [H]

COG id: COG1060

COG function: function code HR; Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the radical SAM superfamily. CofH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR019940
- InterPro:   IPR006638
- InterPro:   IPR020050
- InterPro:   IPR005244
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 39392; Mature: 39261

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFATIAEKVRAGGRITEPEALVLFEHPDLLALGELAQSVNERRNGKRVFFNVNRHINHT
CCHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCHH
NICVNRCRFCAFFRKAGDPGAYLMTLDEVRGRAEEAVKEGATEIHVVGGLHPELPFEFYL
HHHHHHHHHHHHHHHCCCCCEEEEEHHHHCCHHHHHHHCCCCEEEEEECCCCCCCHHHHH
ELLATVKAVSPALHVKAFTAVEIAYLAKLSGLGIPATLEKLKEAGLGSLPGGGAEIFAPE
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCEEECHH
IRNQLCPEKISGAAWLSIMEQVHQAGLKSNATMLYGHLESVADRVDHMRQLRELQDRTGG
HHHHCCHHHHCHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCC
FQVFIPLAFQPEHSQLKIAGSGTSGVDDLRTLAVARIYLDNFANVKAYWVMLGEKIAQVS
EEEEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
LSFGVNDLDGTVVEERIGHEAGADTPQTMSRDNIVTMIRKAGRIPVERDTLYQELRVY
HHCCCCCCCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
TFATIAEKVRAGGRITEPEALVLFEHPDLLALGELAQSVNERRNGKRVFFNVNRHINHT
CHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCHH
NICVNRCRFCAFFRKAGDPGAYLMTLDEVRGRAEEAVKEGATEIHVVGGLHPELPFEFYL
HHHHHHHHHHHHHHHCCCCCEEEEEHHHHCCHHHHHHHCCCCEEEEEECCCCCCCHHHHH
ELLATVKAVSPALHVKAFTAVEIAYLAKLSGLGIPATLEKLKEAGLGSLPGGGAEIFAPE
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCEEECHH
IRNQLCPEKISGAAWLSIMEQVHQAGLKSNATMLYGHLESVADRVDHMRQLRELQDRTGG
HHHHCCHHHHCHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCC
FQVFIPLAFQPEHSQLKIAGSGTSGVDDLRTLAVARIYLDNFANVKAYWVMLGEKIAQVS
EEEEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
LSFGVNDLDGTVVEERIGHEAGADTPQTMSRDNIVTMIRKAGRIPVERDTLYQELRVY
HHCCCCCCCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11930014 [H]