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The map label for this gene is mqnC-1 [H]

Identifier: 197116635

GI number: 197116635

Start: 279025

End: 280098

Strand: Direct

Name: mqnC-1 [H]

Synonym: Gbem_0235

Alternate gene names: 197116635

Gene position: 279025-280098 (Clockwise)

Preceding gene: 197116634

Following gene: 197116636

Centisome position: 6.05

GC content: 65.18

Gene sequence:

>1074_bases
ATGTCGAAAATGTTCCACGCCATAATTGAAAAAGTCGCCGCAGGTGCGGCCATAACCTCAGAAGAAGCGCTCTGGTGCCT
CACCGAAGGGGAGCTCCTCGCCGTGGGGCGTTTAGCCGACTCGATCCGTCGCGCCATGCACCCGGACGGCTGCGTCAGCT
TCGTCGTCGACCGCAACGTCAACTACACCAACGTCTGCGAATCCAGGTGCAAGTTCTGCGCGTTCTACCGTGATGCCGAT
GCGGCGGACGCCTACCTCCTGGATACCGAAGCCATCATGGCGAAGATCGGGGAACTGGTAGCCCAGGGAGGAACCCAGCT
CCTGATGCAGGGGGGGCTCCACCCCTCGCTCGACATCGTCTGGTTCGAGGAGCTCTTCAGGGAGATCAAGCGCCGCTTTC
CCGGCGTGCAAAACCACTCGCTCTCCCCGGCCGAGGTGACCCAGGTGGCGAAGCTCTCCGGGCTTGGCATCGGTGAAACG
CTTACGCGGCTGAAGCGGGCCGGGCTGGACTCCATTCCCGGAGGGGGGGCCGAGATTCTGGTCGACAGTGTCCGCGCCGA
GATCTCACCGAAGAAGATCGGCTGGCAGGGATGGGCGCAGGTCATGCGCGAGGCGGCGCGGTTAGGGATGCCCACCACGG
CGACCATGATGTTCGGCAGCCGCGAGCGCGCCGAAGACATCGTCGAGCACCTGTTCCGGGTGCGCGCCCTGCAGGACGAG
GGAGGTAGCTTCACCGCCTTCATCCCCTGGACCTATCAGCCGGGGAACACCGAGCTCGGGGGGGAGGGTGCCAGCGGCGT
CGAGTACCTGAAGGTGCTGGCCCTGTCGCGCATCGTGCTCAGGAACGTGCCGAACGTGCAGGCGAGCTGGGTGACCCAGG
GTGCCAAGATGGCGCAGGTGGCGCTTTTCTTCGGCGCCAACGACCTGGGCGGAACCATGCTGGAGGAGAACGTGGTGGCG
GCCGCAGGCTGCCGCTTCCGTATGTCGCGCGAGGAGATGATCACGCTGATCCGCGGCGCCGGGTTCACCCCGGTCCGGCG
CACCACCCTGTACCAGGAATTGGAGCGCTACTGA

Upstream 100 bases:

>100_bases
GCGGGACACCCTCTACCAGGAACTGCGCGTCTATTGAGAAGGGGACCGCGCCTGCGTCGGACCATTGCAATGAAGCCTGC
GAAACCACGGAAGTAAGCCA

Downstream 100 bases:

>100_bases
CCGCCGCTCGGTGGCTCTATCGCCTCTTCGTTGTCAATTGTCAATTGTCCATTGTCAATTGCCTTTGCCTCTTGTTATAT
TCACCTGATCTTTTGCCCTG

Product: dehypoxanthinylfutalosine cyclase

Products: NA

Alternate protein names: 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit 2 [H]

Number of amino acids: Translated: 357; Mature: 356

Protein sequence:

>357_residues
MSKMFHAIIEKVAAGAAITSEEALWCLTEGELLAVGRLADSIRRAMHPDGCVSFVVDRNVNYTNVCESRCKFCAFYRDAD
AADAYLLDTEAIMAKIGELVAQGGTQLLMQGGLHPSLDIVWFEELFREIKRRFPGVQNHSLSPAEVTQVAKLSGLGIGET
LTRLKRAGLDSIPGGGAEILVDSVRAEISPKKIGWQGWAQVMREAARLGMPTTATMMFGSRERAEDIVEHLFRVRALQDE
GGSFTAFIPWTYQPGNTELGGEGASGVEYLKVLALSRIVLRNVPNVQASWVTQGAKMAQVALFFGANDLGGTMLEENVVA
AAGCRFRMSREEMITLIRGAGFTPVRRTTLYQELERY

Sequences:

>Translated_357_residues
MSKMFHAIIEKVAAGAAITSEEALWCLTEGELLAVGRLADSIRRAMHPDGCVSFVVDRNVNYTNVCESRCKFCAFYRDAD
AADAYLLDTEAIMAKIGELVAQGGTQLLMQGGLHPSLDIVWFEELFREIKRRFPGVQNHSLSPAEVTQVAKLSGLGIGET
LTRLKRAGLDSIPGGGAEILVDSVRAEISPKKIGWQGWAQVMREAARLGMPTTATMMFGSRERAEDIVEHLFRVRALQDE
GGSFTAFIPWTYQPGNTELGGEGASGVEYLKVLALSRIVLRNVPNVQASWVTQGAKMAQVALFFGANDLGGTMLEENVVA
AAGCRFRMSREEMITLIRGAGFTPVRRTTLYQELERY
>Mature_356_residues
SKMFHAIIEKVAAGAAITSEEALWCLTEGELLAVGRLADSIRRAMHPDGCVSFVVDRNVNYTNVCESRCKFCAFYRDADA
ADAYLLDTEAIMAKIGELVAQGGTQLLMQGGLHPSLDIVWFEELFREIKRRFPGVQNHSLSPAEVTQVAKLSGLGIGETL
TRLKRAGLDSIPGGGAEILVDSVRAEISPKKIGWQGWAQVMREAARLGMPTTATMMFGSRERAEDIVEHLFRVRALQDEG
GSFTAFIPWTYQPGNTELGGEGASGVEYLKVLALSRIVLRNVPNVQASWVTQGAKMAQVALFFGANDLGGTMLEENVVAA
AGCRFRMSREEMITLIRGAGFTPVRRTTLYQELERY

Specific function: Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) [H]

COG id: COG1060

COG function: function code HR; Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the radical SAM superfamily. CofH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR019940
- InterPro:   IPR006638
- InterPro:   IPR020050
- InterPro:   IPR005244
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 39114; Mature: 38983

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKMFHAIIEKVAAGAAITSEEALWCLTEGELLAVGRLADSIRRAMHPDGCVSFVVDRNV
CHHHHHHHHHHHHCCCCCCCCCCEEEECCCCEEEHHHHHHHHHHHCCCCCCEEEEEECCC
NYTNVCESRCKFCAFYRDADAADAYLLDTEAIMAKIGELVAQGGTQLLMQGGLHPSLDIV
CHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHCCCHHHHHHCCCCCCHHHH
WFEELFREIKRRFPGVQNHSLSPAEVTQVAKLSGLGIGETLTRLKRAGLDSIPGGGAEIL
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCHHHH
VDSVRAEISPKKIGWQGWAQVMREAARLGMPTTATMMFGSRERAEDIVEHLFRVRALQDE
HHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHCC
GGSFTAFIPWTYQPGNTELGGEGASGVEYLKVLALSRIVLRNVPNVQASWVTQGAKMAQV
CCCEEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHH
ALFFGANDLGGTMLEENVVAAAGCRFRMSREEMITLIRGAGFTPVRRTTLYQELERY
HHEECCCCCCCHHHHHCHHHHCCCHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SKMFHAIIEKVAAGAAITSEEALWCLTEGELLAVGRLADSIRRAMHPDGCVSFVVDRNV
HHHHHHHHHHHHCCCCCCCCCCEEEECCCCEEEHHHHHHHHHHHCCCCCCEEEEEECCC
NYTNVCESRCKFCAFYRDADAADAYLLDTEAIMAKIGELVAQGGTQLLMQGGLHPSLDIV
CHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHCCCHHHHHHCCCCCCHHHH
WFEELFREIKRRFPGVQNHSLSPAEVTQVAKLSGLGIGETLTRLKRAGLDSIPGGGAEIL
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCHHHH
VDSVRAEISPKKIGWQGWAQVMREAARLGMPTTATMMFGSRERAEDIVEHLFRVRALQDE
HHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHCC
GGSFTAFIPWTYQPGNTELGGEGASGVEYLKVLALSRIVLRNVPNVQASWVTQGAKMAQV
CCCEEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHH
ALFFGANDLGGTMLEENVVAAAGCRFRMSREEMITLIRGAGFTPVRRTTLYQELERY
HHEECCCCCCCHHHHHCHHHHCCCHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]