Click here to switch to the map view.

The map label for this gene is surA [H]

Identifier: 197116616

GI number: 197116616

Start: 256522

End: 257475

Strand: Direct

Name: surA [H]

Synonym: Gbem_0216

Alternate gene names: 197116616

Gene position: 256522-257475 (Clockwise)

Preceding gene: 197116615

Following gene: 197116618

Centisome position: 5.56

GC content: 61.84

Gene sequence:

>954_bases
ATGTCCAAGATCATTATCGGCATCGCCGTGCTGGCGCTTTTGGCGCTGCACCCCGCAGCATCCACCGCGAAACAGGTAAG
CGGCATCGCCGCCATCGTCAACGACGAAATCATCACCACCCAGGAACTGGACAAGGAGTACCTCCAGATCCAGAAGGACG
CGGACAAGGTTCCCGGCTCCGACAAAAGCGGACTTCGGGGAGCGGCGTTGAACCGCCTCGTCGAGAGGAAACTGATCGAG
CAGAAGATCCGCGAGCTCAACATCAACGTTTCCGACGAGGAAGTGCGGCTTGCCATAGAGGACGTGAAGAAGCAGAACAA
CCTGACCCAGGAGAATCTGGAGCAGGCGCTCGTCACCCAGGGGTTGACCCTGGCCCAGTACCGCACCCAGTTGAAGGAAC
AAATGGAGCGCCTGAGGCTGATGAGCCAGGAGGTCCGCTCCAAGGTCCAGGTGGGGGAGCGGGAGATGCGCGAATACTAC
CAGGCGAACATCGCCGCCTACGGCGGCAGCGAGGTTTACAGCGCCCGCCACATATTCTTCAAGGTGGACAAGAAGGGGGG
CGCCGGGGAGCTCTCCAAGGCTGAAACGCGCGCCAACGAGGTGCTGGCCAAAGCGCGCGCCGGAGAGGATTTCGCGGCTC
TGGCCAAGAAGTACTCCGACGACCCGGCGGCAGCCAAAGACGGCGGCGACCTGGGGACCTTCAAGAAGGCCGACATGCTC
CCCGAGATAGGGGACACCGTGTCCGCGATGAAGCCTGGCGAGGTGAGCTCCATTGTGCGCAGCCCAGCCGGGCTGCACAT
CATCAAGCTGGAGGGGAAGAAGCAGGACGCAGGACGCCCCTTCGAGCAGGTGAAGGACTCCATCGAGGACACCCTCTACA
AGAAGAAGTCCGACGAGCGCTTCGCCCAGTGGGTAAAGGAGCTTCGTGCCGGCGCAGCCATAGAACTCCGCTAG

Upstream 100 bases:

>100_bases
GGCGCGCTAGCGCCTGCAGGAACCAGGCAGCACCAACGGCGGCCGGGCATGAGCCCGGCCGTTTTTACTAACCGGCAGCA
AAAGCAATAGAGAGAGCATC

Downstream 100 bases:

>100_bases
CTCCTCTCCCGCAACCCACTGATCAACCACAAAAAAAGCCCCTCCCGGAATCCCCGGAGGGGCTTTTTGCTTTCGCTCCT
GAAGTTACAACCCTTCTGCC

Product: PpiC-type peptidylprolyl cis-trans isomerase

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase surA; PPIase surA; Rotamase surA [H]

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MSKIIIGIAVLALLALHPAASTAKQVSGIAAIVNDEIITTQELDKEYLQIQKDADKVPGSDKSGLRGAALNRLVERKLIE
QKIRELNINVSDEEVRLAIEDVKKQNNLTQENLEQALVTQGLTLAQYRTQLKEQMERLRLMSQEVRSKVQVGEREMREYY
QANIAAYGGSEVYSARHIFFKVDKKGGAGELSKAETRANEVLAKARAGEDFAALAKKYSDDPAAAKDGGDLGTFKKADML
PEIGDTVSAMKPGEVSSIVRSPAGLHIIKLEGKKQDAGRPFEQVKDSIEDTLYKKKSDERFAQWVKELRAGAAIELR

Sequences:

>Translated_317_residues
MSKIIIGIAVLALLALHPAASTAKQVSGIAAIVNDEIITTQELDKEYLQIQKDADKVPGSDKSGLRGAALNRLVERKLIE
QKIRELNINVSDEEVRLAIEDVKKQNNLTQENLEQALVTQGLTLAQYRTQLKEQMERLRLMSQEVRSKVQVGEREMREYY
QANIAAYGGSEVYSARHIFFKVDKKGGAGELSKAETRANEVLAKARAGEDFAALAKKYSDDPAAAKDGGDLGTFKKADML
PEIGDTVSAMKPGEVSSIVRSPAGLHIIKLEGKKQDAGRPFEQVKDSIEDTLYKKKSDERFAQWVKELRAGAAIELR
>Mature_316_residues
SKIIIGIAVLALLALHPAASTAKQVSGIAAIVNDEIITTQELDKEYLQIQKDADKVPGSDKSGLRGAALNRLVERKLIEQ
KIRELNINVSDEEVRLAIEDVKKQNNLTQENLEQALVTQGLTLAQYRTQLKEQMERLRLMSQEVRSKVQVGEREMREYYQ
ANIAAYGGSEVYSARHIFFKVDKKGGAGELSKAETRANEVLAKARAGEDFAALAKKYSDDPAAAKDGGDLGTFKKADMLP
EIGDTVSAMKPGEVSSIVRSPAGLHIIKLEGKKQDAGRPFEQVKDSIEDTLYKKKSDERFAQWVKELRAGAAIELR

Specific function: Chaperone involved in the correct folding and assembly of outer membrane proteins. It recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasm. Note=Is capable of associating with the outer membrane (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PpiC domains [H]

Homologues:

Organism=Escherichia coli, GI1786238, Length=263, Percent_Identity=26.9961977186312, Blast_Score=94, Evalue=2e-20,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR023034
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 34995; Mature: 34864

Theoretical pI: Translated: 8.65; Mature: 8.65

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKIIIGIAVLALLALHPAASTAKQVSGIAAIVNDEIITTQELDKEYLQIQKDADKVPGS
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCC
DKSGLRGAALNRLVERKLIEQKIRELNINVSDEEVRLAIEDVKKQNNLTQENLEQALVTQ
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHC
GLTLAQYRTQLKEQMERLRLMSQEVRSKVQVGEREMREYYQANIAAYGGSEVYSARHIFF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHEEEEE
KVDKKGGAGELSKAETRANEVLAKARAGEDFAALAKKYSDDPAAAKDGGDLGTFKKADML
EEECCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHCC
PEIGDTVSAMKPGEVSSIVRSPAGLHIIKLEGKKQDAGRPFEQVKDSIEDTLYKKKSDER
CHHCCHHHHCCCCHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCHHH
FAQWVKELRAGAAIELR
HHHHHHHHHCCCCEECC
>Mature Secondary Structure 
SKIIIGIAVLALLALHPAASTAKQVSGIAAIVNDEIITTQELDKEYLQIQKDADKVPGS
CHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCC
DKSGLRGAALNRLVERKLIEQKIRELNINVSDEEVRLAIEDVKKQNNLTQENLEQALVTQ
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHC
GLTLAQYRTQLKEQMERLRLMSQEVRSKVQVGEREMREYYQANIAAYGGSEVYSARHIFF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHEEEEE
KVDKKGGAGELSKAETRANEVLAKARAGEDFAALAKKYSDDPAAAKDGGDLGTFKKADML
EEECCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHCC
PEIGDTVSAMKPGEVSSIVRSPAGLHIIKLEGKKQDAGRPFEQVKDSIEDTLYKKKSDER
CHHCCHHHHCCCCHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCHHH
FAQWVKELRAGAAIELR
HHHHHHHHHCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA