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The map label for this gene is nuoG-2 [H]

Identifier: 197116575

GI number: 197116575

Start: 204007

End: 205953

Strand: Reverse

Name: nuoG-2 [H]

Synonym: Gbem_0175

Alternate gene names: 197116575

Gene position: 205953-204007 (Counterclockwise)

Preceding gene: 197116576

Following gene: 197116574

Centisome position: 4.46

GC content: 66.2

Gene sequence:

>1947_bases
ATGCCGAAGCTGATCATAGATGACATACCGGTGGAGGTCCCGCCGGGAACCAGCGTGCTGGAAGCCGCCCGCAGCGTCGG
GATCACCATCCCGCACTTCTGCTACCACCCGGCGCTCGCCATCGCCGCCGCCTGCCGCCTCTGCGCCGTGAAGCTTCTGG
ACGGGCCGGTGAAGGGTATCCAGATGTCTTGCTCGCTCCCAGCGCAAGACGGGATGGTGGTCTCCACCACCGATCCCGAA
GCGCTCAAGATGCGCTCGCTGGTCATCGAATGGCTCATGCTGAACCACCCTCACGACTGCCCGGTCTGCGACGAGGGGGG
GGAGTGCCTCTTGCAGGACTTCACCATCGCCGGCGGTCACAGCCGCCGCAGGTATGTGGGCAAGAAGCGGACCTTCCAGA
ACCAGTACCTCGGTGAGGGGATCCACCACGAGATGAACCGCTGCATCGAATGCTACCGCTGCGTCAGGTTCTACCAGGAG
TACGCCGGCGGCACCGATTTCGGCGTCACCGGGAGCGCGGGGCGGGTCTATTTCGGCAGGTTCGCCGAAGGAGCGCTGGA
GTCCCCCTTCTCCGGGAACCTGGTGGATATCTGCCCGACCGGGGTCTTCACCGACAAGACGGGACGCTTCCGGGCGCGCT
ACTGGGACTACGAGTTCGCCCCCGCCGTCTGCCAGCACTGCTCGGTCGGCTGCAACACCTCGCCCCAGAACTTCCAGCGG
GAGCTGATCAAGATCGTGGCGCGCAGAAACGACCAGGTGAACGGCTGGTTCATCTGCGACCGGGGGCGCTTCGACAAGGA
GTACCTGAACGGCCCGCAACGGCCGCGCTACCCCGAGATCGGCGGCGCCCCGGGGGAATACCGCTTGGCCCTGGAGGCGG
CGGCGAACCGCATCTCCGAGTTCTGCCTGCAAAACGGCCCGGCAGGCCTCGCCTTCGTAGGCTCCGGACGGCTCTCGCTG
GAGGGGTGCCTGGTGCTCGCCGAACTGGCGCGGGTCGTGGGGGCGCCTGTTTCATATTTTGCCGAAGCGGCACCGGCGCA
GGGAAGCCTCGCCGCGGTCCGGCTCCTGAACGAGCAGAACGCTGCCCGCATCCACGACATCGAGAAGGCGGAGTGCATCG
CGCTCTTCGAGCTGGACCTTATGGAAGAGGGGGCCATGCTCTCGCTCGCGGTCCGGAAAGCGTCGCTAGCCGGGGCGCAG
GTATTCCGCGTGGGAGGGGCAAGGGAGGGGGAAAAGCGCCAGCTCCCTTTCCGCTACCAGGAGGTTGCGACGCTCGACGA
GGTTCCTTTCGAGGGAGGGTCCAAGGGAGTGGTCATCTGCGGCGCCGGTGGGAAGTCCCCCGAACTTCTCTCCTATCTCG
CCTCAAGCGGCGCCAGGCTCGTGATGCTGCAACCTGGCCCCAACGCTTTCGGCGCCGCCCTGGTCAGCCTGGAAAGAAAG
GGCGCCACCCTCTCCGACCTGGTCGAGTCGGGCCAGATCAAGGCGGTGGTCTGTTTCGAGGCGGACCTCCCCCCCTGGCT
GCTGGAGCGGGTGGAGGTGCTGGCCTGCGCCGACTGGAAACGCGGCGGCTTAACCGAGAAGGCTTCCGTGCTCCTCCCCA
CCACCACCTGGGTCGAGTCGAACGGGACCAGCATCAACTACGAGGGGAGAGCGCAGCGCTTCCTGCGCAGCCGGCCGGCG
GGGCTTCCGCTCAAGGGGCTGGACCCAAAGTACTACTCAAGCGAGACCGAGGCGGTCGCCCTGCACCCGCCCCACGTGCA
CCGGAACTACATCCCCGGAGGAGCTGAACGGGAGGCCTGGCGGGTCATGGCCGACCTGATGCTGGAACTGGGGGGCGAAC
CCGTCAACGAGCCGCTCACGGGTACATGGGGCAAACTGAGAGACCTTGATCCCGAGGGGGAAGGGGTGCGTATTTACGAT
CTCGTCTCCGCACAGGAATTATCATGA

Upstream 100 bases:

>100_bases
GACGGGCTTTTGCGGCACTTCGAGGACGAGGTGCGGGAGCATATCGTGAAGAAGAAATGTCCCTTGAAGAAATAGGGCGA
AAGGACCGTAGAGCTATCAG

Downstream 100 bases:

>100_bases
CGACCTGGGACGCCTTAGACATAGCGCTTATGCTGGGGAAGATCGTCGTGCTCTTCGCCATCATCCTCACGCTCGCCGCC
TACATGGTGCTGGCCGAGAG

Product: NADH dehydrogenase subunit G

Products: NA

Alternate protein names: NADH dehydrogenase I subunit G; NDH-1 subunit G [H]

Number of amino acids: Translated: 648; Mature: 647

Protein sequence:

>648_residues
MPKLIIDDIPVEVPPGTSVLEAARSVGITIPHFCYHPALAIAAACRLCAVKLLDGPVKGIQMSCSLPAQDGMVVSTTDPE
ALKMRSLVIEWLMLNHPHDCPVCDEGGECLLQDFTIAGGHSRRRYVGKKRTFQNQYLGEGIHHEMNRCIECYRCVRFYQE
YAGGTDFGVTGSAGRVYFGRFAEGALESPFSGNLVDICPTGVFTDKTGRFRARYWDYEFAPAVCQHCSVGCNTSPQNFQR
ELIKIVARRNDQVNGWFICDRGRFDKEYLNGPQRPRYPEIGGAPGEYRLALEAAANRISEFCLQNGPAGLAFVGSGRLSL
EGCLVLAELARVVGAPVSYFAEAAPAQGSLAAVRLLNEQNAARIHDIEKAECIALFELDLMEEGAMLSLAVRKASLAGAQ
VFRVGGAREGEKRQLPFRYQEVATLDEVPFEGGSKGVVICGAGGKSPELLSYLASSGARLVMLQPGPNAFGAALVSLERK
GATLSDLVESGQIKAVVCFEADLPPWLLERVEVLACADWKRGGLTEKASVLLPTTTWVESNGTSINYEGRAQRFLRSRPA
GLPLKGLDPKYYSSETEAVALHPPHVHRNYIPGGAEREAWRVMADLMLELGGEPVNEPLTGTWGKLRDLDPEGEGVRIYD
LVSAQELS

Sequences:

>Translated_648_residues
MPKLIIDDIPVEVPPGTSVLEAARSVGITIPHFCYHPALAIAAACRLCAVKLLDGPVKGIQMSCSLPAQDGMVVSTTDPE
ALKMRSLVIEWLMLNHPHDCPVCDEGGECLLQDFTIAGGHSRRRYVGKKRTFQNQYLGEGIHHEMNRCIECYRCVRFYQE
YAGGTDFGVTGSAGRVYFGRFAEGALESPFSGNLVDICPTGVFTDKTGRFRARYWDYEFAPAVCQHCSVGCNTSPQNFQR
ELIKIVARRNDQVNGWFICDRGRFDKEYLNGPQRPRYPEIGGAPGEYRLALEAAANRISEFCLQNGPAGLAFVGSGRLSL
EGCLVLAELARVVGAPVSYFAEAAPAQGSLAAVRLLNEQNAARIHDIEKAECIALFELDLMEEGAMLSLAVRKASLAGAQ
VFRVGGAREGEKRQLPFRYQEVATLDEVPFEGGSKGVVICGAGGKSPELLSYLASSGARLVMLQPGPNAFGAALVSLERK
GATLSDLVESGQIKAVVCFEADLPPWLLERVEVLACADWKRGGLTEKASVLLPTTTWVESNGTSINYEGRAQRFLRSRPA
GLPLKGLDPKYYSSETEAVALHPPHVHRNYIPGGAEREAWRVMADLMLELGGEPVNEPLTGTWGKLRDLDPEGEGVRIYD
LVSAQELS
>Mature_647_residues
PKLIIDDIPVEVPPGTSVLEAARSVGITIPHFCYHPALAIAAACRLCAVKLLDGPVKGIQMSCSLPAQDGMVVSTTDPEA
LKMRSLVIEWLMLNHPHDCPVCDEGGECLLQDFTIAGGHSRRRYVGKKRTFQNQYLGEGIHHEMNRCIECYRCVRFYQEY
AGGTDFGVTGSAGRVYFGRFAEGALESPFSGNLVDICPTGVFTDKTGRFRARYWDYEFAPAVCQHCSVGCNTSPQNFQRE
LIKIVARRNDQVNGWFICDRGRFDKEYLNGPQRPRYPEIGGAPGEYRLALEAAANRISEFCLQNGPAGLAFVGSGRLSLE
GCLVLAELARVVGAPVSYFAEAAPAQGSLAAVRLLNEQNAARIHDIEKAECIALFELDLMEEGAMLSLAVRKASLAGAQV
FRVGGAREGEKRQLPFRYQEVATLDEVPFEGGSKGVVICGAGGKSPELLSYLASSGARLVMLQPGPNAFGAALVSLERKG
ATLSDLVESGQIKAVVCFEADLPPWLLERVEVLACADWKRGGLTEKASVLLPTTTWVESNGTSINYEGRAQRFLRSRPAG
LPLKGLDPKYYSSETEAVALHPPHVHRNYIPGGAEREAWRVMADLMLELGGEPVNEPLTGTWGKLRDLDPEGEGVRIYDL
VSAQELS

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1034

COG function: function code C; NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI33519475, Length=398, Percent_Identity=31.9095477386935, Blast_Score=217, Evalue=2e-56,
Organism=Escherichia coli, GI145693161, Length=658, Percent_Identity=37.6899696048632, Blast_Score=365, Evalue=1e-102,
Organism=Caenorhabditis elegans, GI17565758, Length=585, Percent_Identity=30.7692307692308, Blast_Score=220, Evalue=2e-57,
Organism=Caenorhabditis elegans, GI32566231, Length=585, Percent_Identity=30.7692307692308, Blast_Score=220, Evalue=2e-57,
Organism=Caenorhabditis elegans, GI193209088, Length=252, Percent_Identity=39.2857142857143, Blast_Score=191, Evalue=1e-48,
Organism=Drosophila melanogaster, GI24640559, Length=403, Percent_Identity=34.4913151364764, Blast_Score=216, Evalue=4e-56,
Organism=Drosophila melanogaster, GI24640557, Length=403, Percent_Identity=34.4913151364764, Blast_Score=216, Evalue=4e-56,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR006656
- InterPro:   IPR006963
- InterPro:   IPR006655
- InterPro:   IPR000283
- InterPro:   IPR010228
- InterPro:   IPR019574 [H]

Pfam domain/function: PF00111 Fer2; PF04879 Molybdop_Fe4S4; PF00384 Molybdopterin; PF10588 NADH-G_4Fe-4S_3 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 70571; Mature: 70440

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: PS00641 COMPLEX1_75K_1 ; PS00642 COMPLEX1_75K_2 ; PS00643 COMPLEX1_75K_3 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKLIIDDIPVEVPPGTSVLEAARSVGITIPHFCYHPALAIAAACRLCAVKLLDGPVKGI
CCCCEECCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
QMSCSLPAQDGMVVSTTDPEALKMRSLVIEWLMLNHPHDCPVCDEGGECLLQDFTIAGGH
EEEECCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCC
SRRRYVGKKRTFQNQYLGEGIHHEMNRCIECYRCVRFYQEYAGGTDFGVTGSAGRVYFGR
CHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEH
FAEGALESPFSGNLVDICPTGVFTDKTGRFRARYWDYEFAPAVCQHCSVGCNTSPQNFQR
HCCHHHCCCCCCCEEEECCCCEEECCCCCEEEEECCCCHHHHHHHHCCCCCCCCHHHHHH
ELIKIVARRNDQVNGWFICDRGRFDKEYLNGPQRPRYPEIGGAPGEYRLALEAAANRISE
HHHHHHHHCCCCCCEEEEECCCCCCHHHCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHH
FCLQNGPAGLAFVGSGRLSLEGCLVLAELARVVGAPVSYFAEAAPAQGSLAAVRLLNEQN
HHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCHHHEECCCCC
AARIHDIEKAECIALFELDLMEEGAMLSLAVRKASLAGAQVFRVGGAREGEKRQLPFRYQ
CHHHHCCCCCCEEEEEEEHHHCCCCEEEHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHH
EVATLDEVPFEGGSKGVVICGAGGKSPELLSYLASSGARLVMLQPGPNAFGAALVSLERK
HHHHHHCCCCCCCCCCEEEECCCCCCHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHC
GATLSDLVESGQIKAVVCFEADLPPWLLERVEVLACADWKRGGLTEKASVLLPTTTWVES
CCHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEEEEC
NGTSINYEGRAQRFLRSRPAGLPLKGLDPKYYSSETEAVALHPPHVHRNYIPGGAEREAW
CCCEEEECHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCHHHH
RVMADLMLELGGEPVNEPLTGTWGKLRDLDPEGEGVRIYDLVSAQELS
HHHHHHHHHHCCCCCCCCCCCCCCHHCCCCCCCCCEEEEEECCHHCCC
>Mature Secondary Structure 
PKLIIDDIPVEVPPGTSVLEAARSVGITIPHFCYHPALAIAAACRLCAVKLLDGPVKGI
CCCEECCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
QMSCSLPAQDGMVVSTTDPEALKMRSLVIEWLMLNHPHDCPVCDEGGECLLQDFTIAGGH
EEEECCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCC
SRRRYVGKKRTFQNQYLGEGIHHEMNRCIECYRCVRFYQEYAGGTDFGVTGSAGRVYFGR
CHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEH
FAEGALESPFSGNLVDICPTGVFTDKTGRFRARYWDYEFAPAVCQHCSVGCNTSPQNFQR
HCCHHHCCCCCCCEEEECCCCEEECCCCCEEEEECCCCHHHHHHHHCCCCCCCCHHHHHH
ELIKIVARRNDQVNGWFICDRGRFDKEYLNGPQRPRYPEIGGAPGEYRLALEAAANRISE
HHHHHHHHCCCCCCEEEEECCCCCCHHHCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHH
FCLQNGPAGLAFVGSGRLSLEGCLVLAELARVVGAPVSYFAEAAPAQGSLAAVRLLNEQN
HHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCHHHEECCCCC
AARIHDIEKAECIALFELDLMEEGAMLSLAVRKASLAGAQVFRVGGAREGEKRQLPFRYQ
CHHHHCCCCCCEEEEEEEHHHCCCCEEEHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHH
EVATLDEVPFEGGSKGVVICGAGGKSPELLSYLASSGARLVMLQPGPNAFGAALVSLERK
HHHHHHCCCCCCCCCCEEEECCCCCCHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHC
GATLSDLVESGQIKAVVCFEADLPPWLLERVEVLACADWKRGGLTEKASVLLPTTTWVES
CCHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEEEEC
NGTSINYEGRAQRFLRSRPAGLPLKGLDPKYYSSETEAVALHPPHVHRNYIPGGAEREAW
CCCEEEECHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCHHHH
RVMADLMLELGGEPVNEPLTGTWGKLRDLDPEGEGVRIYDLVSAQELS
HHHHHHHHHHCCCCCCCCCCCCCCHHCCCCCCCCCEEEEEECCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]