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The map label for this gene is nuoH-2 [H]

Identifier: 197116574

GI number: 197116574

Start: 203018

End: 204010

Strand: Reverse

Name: nuoH-2 [H]

Synonym: Gbem_0174

Alternate gene names: 197116574

Gene position: 204010-203018 (Counterclockwise)

Preceding gene: 197116575

Following gene: 197116573

Centisome position: 4.42

GC content: 61.83

Gene sequence:

>993_bases
ATGACGACCTGGGACGCCTTAGACATAGCGCTTATGCTGGGGAAGATCGTCGTGCTCTTCGCCATCATCCTCACGCTCGC
CGCCTACATGGTGCTGGCCGAGAGGCGCATCCTCGGCTGGATCCAGGATCGCATCGGCCCGAACCGCGTCGGCCCCTTCG
GCCTGCTCCAGCCGCTGGCCGACGTCATCAAGATGCTCACCAAGGAAGACATGATCCCCAAGGCGGCGGACCGCTTCCTC
TTTTCCGTGGCACCGGCGATGGCTGCTATTCCCGCCATTCTGACCTTCGCCATCATCCCGCTGGGGGCGCCGACCGTTCT
TTTCGGACACGAAGTCAACCTCCAGATCGCCGACCTGGACGTAGGCGTGCTGGTCTTTCTCGCCCTTTCATCCATCGCCG
TCTACGGCGTCGCGCTGGGCGGGTGGGCGTCCAACTCGAAGTACGCGCTCCTGGGGAGCATCCGGGGGCTCTCCCAGCTG
ATCTCCTACGAGCTCTCCATGGGGCTTTCGCTGGTTCCCGTGGTGATGCTGGCCAAGTCGCTCAGGCTCTCGGACATCGT
CAACGCCCAGGCGCAGATGCCTTTCATCGTGTACCAGCCTCTCGCCTTCGCGATCTTCCTGGTCAGCATCCTGGCCGAGT
GCCGCAGGATCCCGTTCGACCTCCCCGAGGCGGAAGGGGAACTGGTAGCCGGGTTCCATACCGAGTACTCAGGGATGCGC
TTCGGCCTTTTCTTCGTGGGCGAATACATCAACATCATCTCGCTCAGCGCGCTCGCTTCCCTCTTTTTCCTGGGGGGGTG
GCGCGGACCGCTTTTGCCGCCGATCCTGTGGTTCTTCATCAAGGTCGGACTTTTCGCTTTCGTCTTCATCTGGGTCAGGG
GAACCCTTCCTCGTCTTCGCTACGACCAGCTCATGCACCTGGGCTGGAAGTTCCTGACACCGCTTGCTCTTCTCAACATT
CTGGCCACCGGGTGGTGGCTGGCTTTACGATAG

Upstream 100 bases:

>100_bases
TCAACGAGCCGCTCACGGGTACATGGGGCAAACTGAGAGACCTTGATCCCGAGGGGGAAGGGGTGCGTATTTACGATCTC
GTCTCCGCACAGGAATTATC

Downstream 100 bases:

>100_bases
GGGGCGTTGTACCGGGCAATGTATTCTCACCAAAGGAGGAACTGCGATGACAACAACCGTGGAAGTCGAGTTGGGGGCAG
GGTTCAGGGCACAGGTTGAC

Product: NADH dehydrogenase I subunit H

Products: NA

Alternate protein names: NADH dehydrogenase I subunit H 1; NDH-1 subunit H 1 [H]

Number of amino acids: Translated: 330; Mature: 329

Protein sequence:

>330_residues
MTTWDALDIALMLGKIVVLFAIILTLAAYMVLAERRILGWIQDRIGPNRVGPFGLLQPLADVIKMLTKEDMIPKAADRFL
FSVAPAMAAIPAILTFAIIPLGAPTVLFGHEVNLQIADLDVGVLVFLALSSIAVYGVALGGWASNSKYALLGSIRGLSQL
ISYELSMGLSLVPVVMLAKSLRLSDIVNAQAQMPFIVYQPLAFAIFLVSILAECRRIPFDLPEAEGELVAGFHTEYSGMR
FGLFFVGEYINIISLSALASLFFLGGWRGPLLPPILWFFIKVGLFAFVFIWVRGTLPRLRYDQLMHLGWKFLTPLALLNI
LATGWWLALR

Sequences:

>Translated_330_residues
MTTWDALDIALMLGKIVVLFAIILTLAAYMVLAERRILGWIQDRIGPNRVGPFGLLQPLADVIKMLTKEDMIPKAADRFL
FSVAPAMAAIPAILTFAIIPLGAPTVLFGHEVNLQIADLDVGVLVFLALSSIAVYGVALGGWASNSKYALLGSIRGLSQL
ISYELSMGLSLVPVVMLAKSLRLSDIVNAQAQMPFIVYQPLAFAIFLVSILAECRRIPFDLPEAEGELVAGFHTEYSGMR
FGLFFVGEYINIISLSALASLFFLGGWRGPLLPPILWFFIKVGLFAFVFIWVRGTLPRLRYDQLMHLGWKFLTPLALLNI
LATGWWLALR
>Mature_329_residues
TTWDALDIALMLGKIVVLFAIILTLAAYMVLAERRILGWIQDRIGPNRVGPFGLLQPLADVIKMLTKEDMIPKAADRFLF
SVAPAMAAIPAILTFAIIPLGAPTVLFGHEVNLQIADLDVGVLVFLALSSIAVYGVALGGWASNSKYALLGSIRGLSQLI
SYELSMGLSLVPVVMLAKSLRLSDIVNAQAQMPFIVYQPLAFAIFLVSILAECRRIPFDLPEAEGELVAGFHTEYSGMRF
GLFFVGEYINIISLSALASLFFLGGWRGPLLPPILWFFIKVGLFAFVFIWVRGTLPRLRYDQLMHLGWKFLTPLALLNIL
ATGWWLALR

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1005

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 1 (chain H)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family [H]

Homologues:

Organism=Homo sapiens, GI251831107, Length=292, Percent_Identity=41.4383561643836, Blast_Score=227, Evalue=1e-59,
Organism=Escherichia coli, GI1788618, Length=319, Percent_Identity=48.9028213166144, Blast_Score=310, Evalue=6e-86,
Organism=Escherichia coli, GI1789077, Length=231, Percent_Identity=29.4372294372294, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023020
- InterPro:   IPR001694
- InterPro:   IPR018086 [H]

Pfam domain/function: PF00146 NADHdh [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 36370; Mature: 36239

Theoretical pI: Translated: 8.92; Mature: 8.92

Prosite motif: PS00668 COMPLEX1_ND1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTWDALDIALMLGKIVVLFAIILTLAAYMVLAERRILGWIQDRIGPNRVGPFGLLQPLA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
DVIKMLTKEDMIPKAADRFLFSVAPAMAAIPAILTFAIIPLGAPTVLFGHEVNLQIADLD
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCEEEEEEECCH
VGVLVFLALSSIAVYGVALGGWASNSKYALLGSIRGLSQLISYELSMGLSLVPVVMLAKS
HHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
LRLSDIVNAQAQMPFIVYQPLAFAIFLVSILAECRRIPFDLPEAEGELVAGFHTEYSGMR
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCH
FGLFFVGEYINIISLSALASLFFLGGWRGPLLPPILWFFIKVGLFAFVFIWVRGTLPRLR
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
YDQLMHLGWKFLTPLALLNILATGWWLALR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TTWDALDIALMLGKIVVLFAIILTLAAYMVLAERRILGWIQDRIGPNRVGPFGLLQPLA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
DVIKMLTKEDMIPKAADRFLFSVAPAMAAIPAILTFAIIPLGAPTVLFGHEVNLQIADLD
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCEEEEEEECCH
VGVLVFLALSSIAVYGVALGGWASNSKYALLGSIRGLSQLISYELSMGLSLVPVVMLAKS
HHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
LRLSDIVNAQAQMPFIVYQPLAFAIFLVSILAECRRIPFDLPEAEGELVAGFHTEYSGMR
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCH
FGLFFVGEYINIISLSALASLFFLGGWRGPLLPPILWFFIKVGLFAFVFIWVRGTLPRLR
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
YDQLMHLGWKFLTPLALLNILATGWWLALR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA