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The map label for this gene is acaA [H]

Identifier: 197105987

GI number: 197105987

Start: 2899691

End: 2901244

Strand: Reverse

Name: acaA [H]

Synonym: PHZ_c2526

Alternate gene names: 197105987

Gene position: 2901244-2899691 (Counterclockwise)

Preceding gene: 197105988

Following gene: 197105986

Centisome position: 72.6

GC content: 70.46

Gene sequence:

>1554_bases
GTGCGCCGCCTTCCAGGTGCGCGCCGCCGGCCGCGACGTGGTGGTGCAGCGGAACGGATACGCGGAGTTCGGAGCATAGA
CATGGTCGGGATCATCGCAGCGGGCGCCTATGTCCCGCGCCTTCGACTTCAGAAGCAGGCGATCGCCGCCGCGCACGCCT
GGTTCGCGCCCGGCCTCAAGGGCTTGGCCAAGGGCGAGCGCGCGATGGCCAACTGGGACGAGGACGCCATCACCATGGCC
GTGGAAGCAGCGCGCGACGCCCTGGCCGGACTGGATCGCGGCCGGGTCGGCCGCGTGGTTCTGGCCTCCACGAGCCATCC
GAACGCCGACCGTCAGAACGCCGGGATCGTCAAGGAGGCCCTGAACCTCGCCGACGAGGTCGCGGCGATGGACGTCGGGG
GCAGCCAGCGGGCCGCCACCTCGGCGCTGCTGGACGCGCTCTACGCCGCGCGGGGCGGGGCGGGCGAAGCGCTGTGTGTC
GCGTCCGAGAAGCGTCGGGCGCAACCCGCCTCGGAGCTGGAGCTGACGACCGGGGACGCCGCCGTGGCGCTGCTGGTGGG
CGAGGACGCCGTGGCCGCGGAATTCCTGGGCGGCCACAGCGTCTCCATCGACTTCGTCGATCACTTCCGCGGCGCGGACA
AGGCGTTCGACTACAACTGGGAAGCCCGCTGGGTCCGCGACGAAGGCTACGCCAAGATCGCGCCCAGGGCCGTGAAGGGC
GCGTTGGCCAAGGCCGGGGTGACGGCGGGCGAGGTCGACCACTTCATCATGGGCGCGCCGATGAAGGGCGTGAACGACAC
GGTGGCCAAGGCCTCGGGCATCGTCCCGGAGAACGTGGTCGATCCGCTGACCGGCGAGCTGGGCGAGGTCGGCACGGCCC
AGCCGCTGATCCTACTCGCCCATGCGCTCGAGACCGCCAGGGCCGGCGAGATACTGGTGGTGGCCGGCTTCGGCCAGGGC
TGCGACGTGCTGGTGTTCCGGGCGACCGGCCAGCCGGCGGTCCGCGGCCTGGGCGTCTCGGGCTGGCTGGCGCGGAAGAA
GCCTGAAGCCAACTACGTGAAGTACCTCACGCTGAACGGGCACCTGAACGTGGAGCGTGGCATGCGCGCCGAGTTCGACC
AGAAGACCGCCCTGACAGCCCTGAACCGCAGCCGCAAGGCGGTCATGGCGCTGGTGGGGGGCCGCTGCACCAAGACCGGG
ACCATCCAATTCCCGAAGAGCCCGATCAGCGTGGCGCAGAACGACCGGGCCCAGAACACGCAGGAGGACTATCCCTTCGC
CGACCGGCGGGCGCGGATCGTCACCCACACGGCCGACAGCCTGACCTATTCGCCCGATCCGCCGTGCTGGTACGGCGCCA
TCGAGTTCGAGGAGGGCGGCCGGATGACGGTCGAGTTCGCCGACGTCGATCCCGACGACGTGGAGGTCGGCGCGTCGATG
CGCATGATGTTCCGGATCAAGGCCGTCGACGATCGGCGGGGCTTCACGAAGTACTTCTGGAAAGCGGTCCCGGACTACCT
GGCGGGCAACCCCGCGCAGCTGGCGGCGGAATAG

Upstream 100 bases:

>100_bases
ACGACGACCCGGCCCGGCTGCGCAGGCTGGATGTACGCTTCTCCAGCCCGGCCTATCCTGGGGACCGGTTCGAGATCGAC
GTCTGGCGGGCGCCGGAGGG

Downstream 100 bases:

>100_bases
GAGCGAAGGTCATGGCGAGCGGCATCAAGGACCGGGTTGCGATCCTGGGTATGGGCTGCGCCCGCTTCGGTGAGCGCTGG
AACGACGACGCCGAGACCCT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 517; Mature: 517

Protein sequence:

>517_residues
MRRLPGARRRPRRGGAAERIRGVRSIDMVGIIAAGAYVPRLRLQKQAIAAAHAWFAPGLKGLAKGERAMANWDEDAITMA
VEAARDALAGLDRGRVGRVVLASTSHPNADRQNAGIVKEALNLADEVAAMDVGGSQRAATSALLDALYAARGGAGEALCV
ASEKRRAQPASELELTTGDAAVALLVGEDAVAAEFLGGHSVSIDFVDHFRGADKAFDYNWEARWVRDEGYAKIAPRAVKG
ALAKAGVTAGEVDHFIMGAPMKGVNDTVAKASGIVPENVVDPLTGELGEVGTAQPLILLAHALETARAGEILVVAGFGQG
CDVLVFRATGQPAVRGLGVSGWLARKKPEANYVKYLTLNGHLNVERGMRAEFDQKTALTALNRSRKAVMALVGGRCTKTG
TIQFPKSPISVAQNDRAQNTQEDYPFADRRARIVTHTADSLTYSPDPPCWYGAIEFEEGGRMTVEFADVDPDDVEVGASM
RMMFRIKAVDDRRGFTKYFWKAVPDYLAGNPAQLAAE

Sequences:

>Translated_517_residues
MRRLPGARRRPRRGGAAERIRGVRSIDMVGIIAAGAYVPRLRLQKQAIAAAHAWFAPGLKGLAKGERAMANWDEDAITMA
VEAARDALAGLDRGRVGRVVLASTSHPNADRQNAGIVKEALNLADEVAAMDVGGSQRAATSALLDALYAARGGAGEALCV
ASEKRRAQPASELELTTGDAAVALLVGEDAVAAEFLGGHSVSIDFVDHFRGADKAFDYNWEARWVRDEGYAKIAPRAVKG
ALAKAGVTAGEVDHFIMGAPMKGVNDTVAKASGIVPENVVDPLTGELGEVGTAQPLILLAHALETARAGEILVVAGFGQG
CDVLVFRATGQPAVRGLGVSGWLARKKPEANYVKYLTLNGHLNVERGMRAEFDQKTALTALNRSRKAVMALVGGRCTKTG
TIQFPKSPISVAQNDRAQNTQEDYPFADRRARIVTHTADSLTYSPDPPCWYGAIEFEEGGRMTVEFADVDPDDVEVGASM
RMMFRIKAVDDRRGFTKYFWKAVPDYLAGNPAQLAAE
>Mature_517_residues
MRRLPGARRRPRRGGAAERIRGVRSIDMVGIIAAGAYVPRLRLQKQAIAAAHAWFAPGLKGLAKGERAMANWDEDAITMA
VEAARDALAGLDRGRVGRVVLASTSHPNADRQNAGIVKEALNLADEVAAMDVGGSQRAATSALLDALYAARGGAGEALCV
ASEKRRAQPASELELTTGDAAVALLVGEDAVAAEFLGGHSVSIDFVDHFRGADKAFDYNWEARWVRDEGYAKIAPRAVKG
ALAKAGVTAGEVDHFIMGAPMKGVNDTVAKASGIVPENVVDPLTGELGEVGTAQPLILLAHALETARAGEILVVAGFGQG
CDVLVFRATGQPAVRGLGVSGWLARKKPEANYVKYLTLNGHLNVERGMRAEFDQKTALTALNRSRKAVMALVGGRCTKTG
TIQFPKSPISVAQNDRAQNTQEDYPFADRRARIVTHTADSLTYSPDPPCWYGAIEFEEGGRMTVEFADVDPDDVEVGASM
RMMFRIKAVDDRRGFTKYFWKAVPDYLAGNPAQLAAE

Specific function: Unknown

COG id: COG3425

COG function: function code I; 3-hydroxy-3-methylglutaryl CoA synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0219 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004656
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: NA

Molecular weight: Translated: 55218; Mature: 55218

Theoretical pI: Translated: 8.30; Mature: 8.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRLPGARRRPRRGGAAERIRGVRSIDMVGIIAAGAYVPRLRLQKQAIAAAHAWFAPGLK
CCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHH
GLAKGERAMANWDEDAITMAVEAARDALAGLDRGRVGRVVLASTSHPNADRQNAGIVKEA
HHHCCCHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCHHHHHH
LNLADEVAAMDVGGSQRAATSALLDALYAARGGAGEALCVASEKRRAQPASELELTTGDA
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECHHHCCCCCHHEEEECCCE
AVALLVGEDAVAAEFLGGHSVSIDFVDHFRGADKAFDYNWEARWVRDEGYAKIAPRAVKG
EEEEEECCCHHHHHHHCCCEEEEEHHHHCCCCCCCCCCCCEEEEEECCCCCEECCHHHHH
ALAKAGVTAGEVDHFIMGAPMKGVNDTVAKASGIVPENVVDPLTGELGEVGTAQPLILLA
HHHHCCCCCCCCCCEEECCCCCCCCHHHHHHCCCCCHHHCCCCCCCCCCCCCCCHHHHHH
HALETARAGEILVVAGFGQGCDVLVFRATGQPAVRGLGVSGWLARKKPEANYVKYLTLNG
HHHHHCCCCCEEEEEECCCCCEEEEEEECCCCHHHCCCCCCHHHCCCCCCCEEEEEEECC
HLNVERGMRAEFDQKTALTALNRSRKAVMALVGGRCTKTGTIQFPKSPISVAQNDRAQNT
EEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCHHHHCCCCCCCC
QEDYPFADRRARIVTHTADSLTYSPDPPCWYGAIEFEEGGRMTVEFADVDPDDVEVGASM
CCCCCCCCCCEEEEEEECCCCEECCCCCCEEEEEEECCCCEEEEEEECCCCCCHHHCCCE
RMMFRIKAVDDRRGFTKYFWKAVPDYLAGNPAQLAAE
EEEEEEEECCCCCCHHHHHHHHHHHHHCCCCHHHCCC
>Mature Secondary Structure
MRRLPGARRRPRRGGAAERIRGVRSIDMVGIIAAGAYVPRLRLQKQAIAAAHAWFAPGLK
CCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHH
GLAKGERAMANWDEDAITMAVEAARDALAGLDRGRVGRVVLASTSHPNADRQNAGIVKEA
HHHCCCHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCHHHHHH
LNLADEVAAMDVGGSQRAATSALLDALYAARGGAGEALCVASEKRRAQPASELELTTGDA
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECHHHCCCCCHHEEEECCCE
AVALLVGEDAVAAEFLGGHSVSIDFVDHFRGADKAFDYNWEARWVRDEGYAKIAPRAVKG
EEEEEECCCHHHHHHHCCCEEEEEHHHHCCCCCCCCCCCCEEEEEECCCCCEECCHHHHH
ALAKAGVTAGEVDHFIMGAPMKGVNDTVAKASGIVPENVVDPLTGELGEVGTAQPLILLA
HHHHCCCCCCCCCCEEECCCCCCCCHHHHHHCCCCCHHHCCCCCCCCCCCCCCCHHHHHH
HALETARAGEILVVAGFGQGCDVLVFRATGQPAVRGLGVSGWLARKKPEANYVKYLTLNG
HHHHHCCCCCEEEEEECCCCCEEEEEEECCCCHHHCCCCCCHHHCCCCCCCEEEEEEECC
HLNVERGMRAEFDQKTALTALNRSRKAVMALVGGRCTKTGTIQFPKSPISVAQNDRAQNT
EEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCHHHHCCCCCCCC
QEDYPFADRRARIVTHTADSLTYSPDPPCWYGAIEFEEGGRMTVEFADVDPDDVEVGASM
CCCCCCCCCCEEEEEEECCCCEECCCCCCEEEEEEECCCCEEEEEEECCCCCCHHHCCCE
RMMFRIKAVDDRRGFTKYFWKAVPDYLAGNPAQLAAE
EEEEEEEECCCCCCHHHHHHHHHHHHHCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]