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The map label for this gene is 197105898

Identifier: 197105898

GI number: 197105898

Start: 2783406

End: 2785487

Strand: Reverse

Name: 197105898

Synonym: PHZ_c2437

Alternate gene names: NA

Gene position: 2785487-2783406 (Counterclockwise)

Preceding gene: 197105899

Following gene: 197105897

Centisome position: 69.7

GC content: 65.18

Gene sequence:

>2082_bases
GTGCGCGCGGCGACCGACGTTGGTGGGACCTTTACGGACCTGGTCTATTACGAAGTTGACCCCGCGACCGGCCGCTCCGG
CCAGGTGAAGATCGCTAAGGTCGACACCACCCCCCCGAACTTCGAAGAGGGGGTGGTCGGGGCGCTCGCCAAGGCAAGTA
TCGCGCCGGCGAAGCTTGATTTCTTCGCTCACGGCGCCACCGTGGTGATCAACGCGCTGACGGAGCGGAAGGGCGTCAGG
ACGGCGCTGATCACGACAGCAGGTTTCCGTGATGTCCTGGAGATCGCCCGCGGGAATCGTCCCGATCTCTTCAACTTCGC
CTTTCATAAGCCGAAGCCCTTCGTGGAGCGCCACCTGCGCGCTGAGGTCGTCGAGCGCACGAACTACAAGGGCGAGATCG
AACGCCCCGCTGACCTGACCGGGCTCCCGGAGCTCGTCCTGAAGTTCAAGCGTGAGGGCGTGCAGGCGATCGCGGTCGTC
TTCCTTCACTCATACATCAACCCGCAGAACGAACAGGCTGTCGTACAGCGACTGCGTGAACTCTGGCCGGAGGTATCCAT
CCTCGCGTCCCACGCCGTCAGCCGGGAATGGCGGGAATACGAGCGGACGAGCACCACGGTGCTCTCGGCTTACGTGCACC
CTATCGCGGAGCGCTACATCGGCACGCTGGAGGCCAAACTCGCGGAGCAGGGGTTCACCGGCAAACCGTACATGATGCAG
TCGAACGGGGGCATCACGACGGCCAGGGCCGCGAAGGCGAACCCGATCACCATGGTCGAGTCCGGCCCCGCCAGCGGCAT
ATTCGCGGCGGCCTATGTCGGGAAGGCGATCGGGGCGAACAATCTCATCGTGCTCGACATCGGCGGAACGACCGCCAAGT
GCACTCTGATCGAGGAGGGGCATGTCAAGGTCACGACCGAATACTACATCGAACGTGACGGGAAGAACCCGGGCTACCCG
ATCCAGACGCCGGTTTCCGACATCGTGGAAATCGGCAACGGCGGTGGGTCGATCGCGTGGGTCGATGCTGGCGGCAAGCT
CCATGTCGGGCCGCATTCCGCGGCCGCACGACCGGGGCCGGCGGCCTACGGCCGCGGCGGGGCCAAGGCGACGACGACGG
ACGCCAACCTTGTCCTGGGGCGGATCGATCCCGCCAGCTTCGTAGGCGGCGAGCGCGAGCCGGACTGGAAATCGGTCGAA
GCTGCTTTTGCGCCTCTGCAGGCGGCGCTCGGCATGAGCCGCGAAGAGGTGGCGCGCGGCATCATCCGGATCGCCAACGC
AAACATGACGCGGGCCCTGCGACTCGTATCCACGAACAGGGGGTACGATCCCCGTGACTTCACGCTGATGGCCTTCGGAG
GTGGCGGCGCCATGCACGCCCTGGCGCTCGCGGAGGAGCTGAAGGTTCCTCACGTGGTCATCCCGGTGAACTCCTCCGTG
TTCTCAGCCTGGGGGATGCTGCTCACCGACCTCCGCCGCGACTACCTTCAGACGCGGATGGCGCCGCTAGGTCCCAGCGC
TGTCCCGGTCATGCAGCAGATCTTCGGCGAGCTCGAGGGCGAGGCGCTCAAGGACTACTCGGACGAGAATGAGACGCTGA
CGCGCGACGACATCGGCTTCGAGTATCTCGTCGACATGCGCTACGCCGGGCAACAGCACACCGTGAAGGTCCCCTGTATC
GGAGCCGGGGACGGCGAGATCGATCTGGAAGCTACGGCGAACGCCTTCCACGGTGCGCACCAGAAGCGCTTCACCTACCG
TCTCGATACCGGCATCGAGCTGGTGAACTTCCACCTCATCGCGAAGCGGACTGTGCCAAAGCCGCCGCTAGCGCCGAAAC
CGGTGACGGGCCTCAGGCTCGAGGCGGCGATCAAGGGCGCGCGACGCGTGGATTACGATGTCCACGGCGTTCATGACGCG
ACCATCTACGACGGACTGCGCCTGGAGCCAGGCATGCACTTCGTCGGTCCGGCGGTGATCCAGGAGCCCTCGGTCACCTG
CGTGGTGCCGCCCGGGCATCGCGTCAGCATCGACCAGTTCGGAAACTATCACATCCACCTGTCCTTCGACGGGGAGGCCT
AA

Upstream 100 bases:

>100_bases
GTACGGGACGCGTGGCGACAGAGGTCCCATGGCGTCGAGATCCAGGCGCCCCTGATCCGCGGGCGCGAGACTGATGAAAT
GACGACCCGGAGTAAGTGAA

Downstream 100 bases:

>100_bases
CCCGTGTCGTCAAACCTTTTCACGCTCGAGATCATCAAGGATTCGCTGGTGGCGGTCGGCGAAGAGATGTTCAACGCCAT
GCTGCGGACCAGCATGAGCC

Product: 5-oxoprolinase (ATP-hydrolyzing)

Products: ADP; phosphate; N-carbamoylsarcosine

Alternate protein names: NA

Number of amino acids: Translated: 693; Mature: 693

Protein sequence:

>693_residues
MRAATDVGGTFTDLVYYEVDPATGRSGQVKIAKVDTTPPNFEEGVVGALAKASIAPAKLDFFAHGATVVINALTERKGVR
TALITTAGFRDVLEIARGNRPDLFNFAFHKPKPFVERHLRAEVVERTNYKGEIERPADLTGLPELVLKFKREGVQAIAVV
FLHSYINPQNEQAVVQRLRELWPEVSILASHAVSREWREYERTSTTVLSAYVHPIAERYIGTLEAKLAEQGFTGKPYMMQ
SNGGITTARAAKANPITMVESGPASGIFAAAYVGKAIGANNLIVLDIGGTTAKCTLIEEGHVKVTTEYYIERDGKNPGYP
IQTPVSDIVEIGNGGGSIAWVDAGGKLHVGPHSAAARPGPAAYGRGGAKATTTDANLVLGRIDPASFVGGEREPDWKSVE
AAFAPLQAALGMSREEVARGIIRIANANMTRALRLVSTNRGYDPRDFTLMAFGGGGAMHALALAEELKVPHVVIPVNSSV
FSAWGMLLTDLRRDYLQTRMAPLGPSAVPVMQQIFGELEGEALKDYSDENETLTRDDIGFEYLVDMRYAGQQHTVKVPCI
GAGDGEIDLEATANAFHGAHQKRFTYRLDTGIELVNFHLIAKRTVPKPPLAPKPVTGLRLEAAIKGARRVDYDVHGVHDA
TIYDGLRLEPGMHFVGPAVIQEPSVTCVVPPGHRVSIDQFGNYHIHLSFDGEA

Sequences:

>Translated_693_residues
MRAATDVGGTFTDLVYYEVDPATGRSGQVKIAKVDTTPPNFEEGVVGALAKASIAPAKLDFFAHGATVVINALTERKGVR
TALITTAGFRDVLEIARGNRPDLFNFAFHKPKPFVERHLRAEVVERTNYKGEIERPADLTGLPELVLKFKREGVQAIAVV
FLHSYINPQNEQAVVQRLRELWPEVSILASHAVSREWREYERTSTTVLSAYVHPIAERYIGTLEAKLAEQGFTGKPYMMQ
SNGGITTARAAKANPITMVESGPASGIFAAAYVGKAIGANNLIVLDIGGTTAKCTLIEEGHVKVTTEYYIERDGKNPGYP
IQTPVSDIVEIGNGGGSIAWVDAGGKLHVGPHSAAARPGPAAYGRGGAKATTTDANLVLGRIDPASFVGGEREPDWKSVE
AAFAPLQAALGMSREEVARGIIRIANANMTRALRLVSTNRGYDPRDFTLMAFGGGGAMHALALAEELKVPHVVIPVNSSV
FSAWGMLLTDLRRDYLQTRMAPLGPSAVPVMQQIFGELEGEALKDYSDENETLTRDDIGFEYLVDMRYAGQQHTVKVPCI
GAGDGEIDLEATANAFHGAHQKRFTYRLDTGIELVNFHLIAKRTVPKPPLAPKPVTGLRLEAAIKGARRVDYDVHGVHDA
TIYDGLRLEPGMHFVGPAVIQEPSVTCVVPPGHRVSIDQFGNYHIHLSFDGEA
>Mature_693_residues
MRAATDVGGTFTDLVYYEVDPATGRSGQVKIAKVDTTPPNFEEGVVGALAKASIAPAKLDFFAHGATVVINALTERKGVR
TALITTAGFRDVLEIARGNRPDLFNFAFHKPKPFVERHLRAEVVERTNYKGEIERPADLTGLPELVLKFKREGVQAIAVV
FLHSYINPQNEQAVVQRLRELWPEVSILASHAVSREWREYERTSTTVLSAYVHPIAERYIGTLEAKLAEQGFTGKPYMMQ
SNGGITTARAAKANPITMVESGPASGIFAAAYVGKAIGANNLIVLDIGGTTAKCTLIEEGHVKVTTEYYIERDGKNPGYP
IQTPVSDIVEIGNGGGSIAWVDAGGKLHVGPHSAAARPGPAAYGRGGAKATTTDANLVLGRIDPASFVGGEREPDWKSVE
AAFAPLQAALGMSREEVARGIIRIANANMTRALRLVSTNRGYDPRDFTLMAFGGGGAMHALALAEELKVPHVVIPVNSSV
FSAWGMLLTDLRRDYLQTRMAPLGPSAVPVMQQIFGELEGEALKDYSDENETLTRDDIGFEYLVDMRYAGQQHTVKVPCI
GAGDGEIDLEATANAFHGAHQKRFTYRLDTGIELVNFHLIAKRTVPKPPLAPKPVTGLRLEAAIKGARRVDYDVHGVHDA
TIYDGLRLEPGMHFVGPAVIQEPSVTCVVPPGHRVSIDQFGNYHIHLSFDGEA

Specific function: Unknown

COG id: COG0145

COG function: function code EQ; N-methylhydantoinase A/acetone carboxylase, beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the oxoprolinase family [H]

Homologues:

Organism=Homo sapiens, GI48314820, Length=749, Percent_Identity=29.9065420560748, Blast_Score=206, Evalue=4e-53,
Organism=Caenorhabditis elegans, GI133901900, Length=745, Percent_Identity=25.503355704698, Blast_Score=171, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6322634, Length=648, Percent_Identity=29.9382716049383, Blast_Score=218, Evalue=3e-57,
Organism=Drosophila melanogaster, GI45550492, Length=750, Percent_Identity=29.8666666666667, Blast_Score=233, Evalue=4e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008040
- InterPro:   IPR002821 [H]

Pfam domain/function: PF05378 Hydant_A_N; PF01968 Hydantoinase_A [H]

EC number: 3.5.2.14

Molecular weight: Translated: 74955; Mature: 74955

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAATDVGGTFTDLVYYEVDPATGRSGQVKIAKVDTTPPNFEEGVVGALAKASIAPAKLD
CCCCCCCCCCEEEEEEEEECCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCHHHH
FFAHGATVVINALTERKGVRTALITTAGFRDVLEIARGNRPDLFNFAFHKPKPFVERHLR
HHHCCHHHEEEHHHHCCCCEEEEEEHHCHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHH
AEVVERTNYKGEIERPADLTGLPELVLKFKREGVQAIAVVFLHSYINPQNEQAVVQRLRE
HHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHH
LWPEVSILASHAVSREWREYERTSTTVLSAYVHPIAERYIGTLEAKLAEQGFTGKPYMMQ
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
SNGGITTARAAKANPITMVESGPASGIFAAAYVGKAIGANNLIVLDIGGTTAKCTLIEEG
CCCCEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCCEEEEEECCCEEEEEEEECC
HVKVTTEYYIERDGKNPGYPIQTPVSDIVEIGNGGGSIAWVDAGGKLHVGPHSAAARPGP
CEEEEEEEEEEECCCCCCCCCCCCHHHHHHHCCCCCEEEEEECCCEEEECCCCCCCCCCC
AAYGRGGAKATTTDANLVLGRIDPASFVGGEREPDWKSVEAAFAPLQAALGMSREEVARG
CCCCCCCCCEECCCCEEEEECCCHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHH
IIRIANANMTRALRLVSTNRGYDPRDFTLMAFGGGGAMHALALAEELKVPHVVIPVNSSV
HHHCCCCCHHHEEEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCEEEEECCCHH
FSAWGMLLTDLRRDYLQTRMAPLGPSAVPVMQQIFGELEGEALKDYSDENETLTRDDIGF
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHCCCCCCCEEECCCCCC
EYLVDMRYAGQQHTVKVPCIGAGDGEIDLEATANAFHGAHQKRFTYRLDTGIELVNFHLI
EEEEEHHCCCCCCEEEEEEEECCCCCEEEEECCHHHHCCCCCEEEEEECCCCEEEEEEEE
AKRTVPKPPLAPKPVTGLRLEAAIKGARRVDYDVHGVHDATIYDGLRLEPGMHFVGPAVI
EECCCCCCCCCCCCCCCCEEHHHHCCCHHCCCCCCCCCCHHEECCEEECCCCCCCCHHHC
QEPSVTCVVPPGHRVSIDQFGNYHIHLSFDGEA
CCCCEEEEECCCCEEEHCCCCCEEEEEEECCCC
>Mature Secondary Structure
MRAATDVGGTFTDLVYYEVDPATGRSGQVKIAKVDTTPPNFEEGVVGALAKASIAPAKLD
CCCCCCCCCCEEEEEEEEECCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCHHHH
FFAHGATVVINALTERKGVRTALITTAGFRDVLEIARGNRPDLFNFAFHKPKPFVERHLR
HHHCCHHHEEEHHHHCCCCEEEEEEHHCHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHH
AEVVERTNYKGEIERPADLTGLPELVLKFKREGVQAIAVVFLHSYINPQNEQAVVQRLRE
HHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHH
LWPEVSILASHAVSREWREYERTSTTVLSAYVHPIAERYIGTLEAKLAEQGFTGKPYMMQ
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
SNGGITTARAAKANPITMVESGPASGIFAAAYVGKAIGANNLIVLDIGGTTAKCTLIEEG
CCCCEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCCEEEEEECCCEEEEEEEECC
HVKVTTEYYIERDGKNPGYPIQTPVSDIVEIGNGGGSIAWVDAGGKLHVGPHSAAARPGP
CEEEEEEEEEEECCCCCCCCCCCCHHHHHHHCCCCCEEEEEECCCEEEECCCCCCCCCCC
AAYGRGGAKATTTDANLVLGRIDPASFVGGEREPDWKSVEAAFAPLQAALGMSREEVARG
CCCCCCCCCEECCCCEEEEECCCHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHH
IIRIANANMTRALRLVSTNRGYDPRDFTLMAFGGGGAMHALALAEELKVPHVVIPVNSSV
HHHCCCCCHHHEEEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCEEEEECCCHH
FSAWGMLLTDLRRDYLQTRMAPLGPSAVPVMQQIFGELEGEALKDYSDENETLTRDDIGF
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHCCCCCCCEEECCCCCC
EYLVDMRYAGQQHTVKVPCIGAGDGEIDLEATANAFHGAHQKRFTYRLDTGIELVNFHLI
EEEEEHHCCCCCCEEEEEEEECCCCCEEEEECCHHHHCCCCCEEEEEECCCCEEEEEEEE
AKRTVPKPPLAPKPVTGLRLEAAIKGARRVDYDVHGVHDATIYDGLRLEPGMHFVGPAVI
EECCCCCCCCCCCCCCCCEEHHHHCCCHHCCCCCCCCCCHHEECCEEECCCCCCCCHHHC
QEPSVTCVVPPGHRVSIDQFGNYHIHLSFDGEA
CCCCEEEEECCCCEEEHCCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; N-methylimidazolidine-2,4-dione; H2O

Specific reaction: ATP + N-methylimidazolidine-2,4-dione + 2 H2O = ADP + phosphate + N-carbamoylsarcosine

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]