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The map label for this gene is gpo [H]

Identifier: 197105203

GI number: 197105203

Start: 1950188

End: 1950667

Strand: Reverse

Name: gpo [H]

Synonym: PHZ_c1740

Alternate gene names: 197105203

Gene position: 1950667-1950188 (Counterclockwise)

Preceding gene: 197105204

Following gene: 197105202

Centisome position: 48.81

GC content: 65.42

Gene sequence:

>480_bases
ATGGCTTCCATCTACGACTTCACCGCCGAGACCATCGACGGCGCGCCGGCGCCGCTCGCGGACCACCGCGGCAAGGTGCT
GCTGATCGTGAACACCGCCAGCAAGTGCGGCTTCACGCGCCAGTACGAGGGGCTGGAGGCGCTCTACCGCCGCTATCGCG
ACCGCGGCCTGGTGATCCTCGGCTTCCCCTGCAACCAGTTCGGCGCGCAGGAGCCGGGCGATGCTGAGGAGATCAGGTCC
TTCTGCTCGCTCACCTACGAGGTCGACTTCCCGCTGATGCGGAAGATCGATGTGAACGGCCCGACGGCCCATCCCCTCTA
CGCCTTCCTCAAGAAGGAGAAGAAGGGCGTGCTGGGCACCGAGGCCATCAAGTGGAACTTCACCAAGTTCCTCGTGGACC
GGTCGGGGAAGGTCGTGGACCGCTTCGCCCCCACCGTTGAACCCAAGGCGCTGGAAGGCGCGATCGAGGCTTTGCTCTGA

Upstream 100 bases:

>100_bases
CCGGGTCGTGGACGGGGCGACCGGCGCGCGCTGGCTGCAGGCGTTCAAGGCGCTGATCGAAGAGCCGCTGACGATGATCG
TCTAGGCGGGAGGGTCCGGG

Downstream 100 bases:

>100_bases
TGGCTGATGCGTTCGACGTCGTTGTGATCGGCTCTGGCCCCGGCGGCTACGTCACCGCCATCCGCGCCTCGCAGCTGGGC
TTCAAGACCGCCATCGTGGA

Product: glutathione peroxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 159; Mature: 158

Protein sequence:

>159_residues
MASIYDFTAETIDGAPAPLADHRGKVLLIVNTASKCGFTRQYEGLEALYRRYRDRGLVILGFPCNQFGAQEPGDAEEIRS
FCSLTYEVDFPLMRKIDVNGPTAHPLYAFLKKEKKGVLGTEAIKWNFTKFLVDRSGKVVDRFAPTVEPKALEGAIEALL

Sequences:

>Translated_159_residues
MASIYDFTAETIDGAPAPLADHRGKVLLIVNTASKCGFTRQYEGLEALYRRYRDRGLVILGFPCNQFGAQEPGDAEEIRS
FCSLTYEVDFPLMRKIDVNGPTAHPLYAFLKKEKKGVLGTEAIKWNFTKFLVDRSGKVVDRFAPTVEPKALEGAIEALL
>Mature_158_residues
ASIYDFTAETIDGAPAPLADHRGKVLLIVNTASKCGFTRQYEGLEALYRRYRDRGLVILGFPCNQFGAQEPGDAEEIRSF
CSLTYEVDFPLMRKIDVNGPTAHPLYAFLKKEKKGVLGTEAIKWNFTKFLVDRSGKVVDRFAPTVEPKALEGAIEALL

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI75709200, Length=153, Percent_Identity=49.0196078431373, Blast_Score=139, Evalue=1e-33,
Organism=Homo sapiens, GI90903240, Length=153, Percent_Identity=49.0196078431373, Blast_Score=138, Evalue=2e-33,
Organism=Homo sapiens, GI15618997, Length=156, Percent_Identity=44.8717948717949, Blast_Score=124, Evalue=4e-29,
Organism=Homo sapiens, GI90903238, Length=131, Percent_Identity=49.618320610687, Blast_Score=116, Evalue=8e-27,
Organism=Homo sapiens, GI41406084, Length=184, Percent_Identity=41.304347826087, Blast_Score=107, Evalue=5e-24,
Organism=Homo sapiens, GI192455698, Length=160, Percent_Identity=35.625, Blast_Score=103, Evalue=9e-23,
Organism=Homo sapiens, GI6006001, Length=161, Percent_Identity=40.3726708074534, Blast_Score=97, Evalue=8e-21,
Organism=Homo sapiens, GI4557629, Length=178, Percent_Identity=35.9550561797753, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI32967607, Length=181, Percent_Identity=34.2541436464088, Blast_Score=90, Evalue=1e-18,
Organism=Homo sapiens, GI33186887, Length=155, Percent_Identity=34.8387096774194, Blast_Score=83, Evalue=1e-16,
Organism=Homo sapiens, GI41406082, Length=70, Percent_Identity=54.2857142857143, Blast_Score=68, Evalue=3e-12,
Organism=Escherichia coli, GI1788003, Length=166, Percent_Identity=44.578313253012, Blast_Score=143, Evalue=4e-36,
Organism=Caenorhabditis elegans, GI17535473, Length=160, Percent_Identity=49.375, Blast_Score=157, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI17506887, Length=160, Percent_Identity=47.5, Blast_Score=156, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI193210707, Length=163, Percent_Identity=45.398773006135, Blast_Score=133, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI71993584, Length=159, Percent_Identity=42.7672955974843, Blast_Score=132, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17550320, Length=166, Percent_Identity=37.3493975903614, Blast_Score=115, Evalue=9e-27,
Organism=Caenorhabditis elegans, GI193209493, Length=164, Percent_Identity=36.5853658536585, Blast_Score=112, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI71999642, Length=76, Percent_Identity=44.7368421052632, Blast_Score=80, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71993573, Length=86, Percent_Identity=39.5348837209302, Blast_Score=69, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17507603, Length=107, Percent_Identity=37.3831775700935, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322228, Length=159, Percent_Identity=55.9748427672956, Blast_Score=193, Evalue=1e-50,
Organism=Saccharomyces cerevisiae, GI6319721, Length=158, Percent_Identity=55.0632911392405, Blast_Score=191, Evalue=4e-50,
Organism=Saccharomyces cerevisiae, GI6322826, Length=159, Percent_Identity=49.0566037735849, Blast_Score=155, Evalue=2e-39,
Organism=Drosophila melanogaster, GI24656772, Length=162, Percent_Identity=48.7654320987654, Blast_Score=145, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24656767, Length=161, Percent_Identity=48.4472049689441, Blast_Score=144, Evalue=2e-35,
Organism=Drosophila melanogaster, GI24656777, Length=161, Percent_Identity=48.4472049689441, Blast_Score=144, Evalue=2e-35,
Organism=Drosophila melanogaster, GI85726443, Length=159, Percent_Identity=44.6540880503145, Blast_Score=120, Evalue=5e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: =1.11.1.9 [H]

Molecular weight: Translated: 17705; Mature: 17573

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: PS00460 GLUTATHIONE_PEROXID_1 ; PS00763 GLUTATHIONE_PEROXID_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASIYDFTAETIDGAPAPLADHRGKVLLIVNTASKCGFTRQYEGLEALYRRYRDRGLVIL
CCCCCCCHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCEEEE
GFPCNQFGAQEPGDAEEIRSFCSLTYEVDFPLMRKIDVNGPTAHPLYAFLKKEKKGVLGT
ECCCHHHCCCCCCCHHHHHHHHHEEEEECCCEEEEEECCCCCCHHHHHHHHHHCCCCCCC
EAIKWNFTKFLVDRSGKVVDRFAPTVEPKALEGAIEALL
HHHEEHHHHEECCCCCCCHHHHCCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
ASIYDFTAETIDGAPAPLADHRGKVLLIVNTASKCGFTRQYEGLEALYRRYRDRGLVIL
CCCCCCHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCEEEE
GFPCNQFGAQEPGDAEEIRSFCSLTYEVDFPLMRKIDVNGPTAHPLYAFLKKEKKGVLGT
ECCCHHHCCCCCCCHHHHHHHHHEEEEECCCEEEEEECCCCCCHHHHHHHHHHCCCCCCC
EAIKWNFTKFLVDRSGKVVDRFAPTVEPKALEGAIEALL
HHHEEHHHHEECCCCCCCHHHHCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]