BacMap

Definition	Phenylobacterium zucineum HLK1, complete genome.
Accession	NC_011144
Length	3,996,255

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The map label for this gene is fabG [H]

Identifier: 197104585

GI number: 197104585

Start: 1282490

End: 1283224

Strand: Reverse

Name: fabG [H]

Synonym: PHZ_c1119

Alternate gene names: 197104585

Gene position: 1283224-1282490 (Counterclockwise)

Preceding gene: 197104593

Following gene: 197104584

Centisome position: 32.11

GC content: 72.93

Gene sequence:

>735_bases
GTGAACGAGCTCGATTTCAGCGGCAAGACCGTGCTGGTCGTGGGCGGCTCCAGCGGCATCGGCAACGGCGTCGCCCACGC
CTTCCGCGGGCGCGGAGCGGCCGTCCACGTCTGGGGCACCCGCGCCAGCGCCGCCGATTACGCCGGGGTGGAGGGCTCCG
ACCTCTCCGACCTCGCCTACGCCCAGGTGGACGTCGGCGACCGCGCCGCCATCGAGGCGGCCGAGGCGATCCGGCCGCTG
GACGTGCTGGTGCTGTGCCAGGGCACGGTCCAGTACCGCCGCGCCGAGTTCGAGCCCGAGGGCTGGGACCGGGTGATGGC
CGTGAACCTGGACAGCCTGATGGACTGCGCGCGCAAGTTCCGCGAGACCCTGGCCGAGCGGCGCGGAGTCGTCATCGTGG
TCAGCTCGGTGTCCGGCTTCCAGTCGAACCGCGGCAATCCGGCCTACGCCGCCTCCAAGGCCGGGGCGGTCAGCCTGACC
AAGACCCTGGGCGAGGCCTGGGCGCCCGACGGGATCCGCGTCGTCGGCCTGGCCCCCGGGCTCGTGGACACCAAGCTCAC
CAAGGTGACGACCGAACATCCCGGCCGGCGCGAGGCGGCGCTCCGGTCCATCCCCATCGGCCGGATGGGCACGCCGCAGG
ACATGGCCGGCGCGGCCCTGTTCCTGGCCTCGCCGCTGGCGGCCTATGTCGTCGGCCAGACCCTCATCGTGGACGGAGGC
CTCTCGCTCTCATGA

Upstream 100 bases:

>100_bases
CGATGGTTCTCCGGCCCAGCGCCTCCTGGCAAGGCTGACGGGGCGTCAGCGTTGACCCCCACGCCCTCCGTGCCAGCATC
GGGCGGGGAGGAAGCCACAC

Downstream 100 bases:

>100_bases
CCAGCCGCTCGATCAAGGGCTCGGTCGCCCTCGTCACCGGCGCGGCCGGCGGCATGGGCAGGGCCACCGCCGAACTCTTC
GCCGCCGAGGGCGCGCACGT

Product: 3-oxoacyl-(acyl-carrier protein) reductase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
MNELDFSGKTVLVVGGSSGIGNGVAHAFRGRGAAVHVWGTRASAADYAGVEGSDLSDLAYAQVDVGDRAAIEAAEAIRPL
DVLVLCQGTVQYRRAEFEPEGWDRVMAVNLDSLMDCARKFRETLAERRGVVIVVSSVSGFQSNRGNPAYAASKAGAVSLT
KTLGEAWAPDGIRVVGLAPGLVDTKLTKVTTEHPGRREAALRSIPIGRMGTPQDMAGAALFLASPLAAYVVGQTLIVDGG
LSLS

Sequences:

>Translated_244_residues
MNELDFSGKTVLVVGGSSGIGNGVAHAFRGRGAAVHVWGTRASAADYAGVEGSDLSDLAYAQVDVGDRAAIEAAEAIRPL
DVLVLCQGTVQYRRAEFEPEGWDRVMAVNLDSLMDCARKFRETLAERRGVVIVVSSVSGFQSNRGNPAYAASKAGAVSLT
KTLGEAWAPDGIRVVGLAPGLVDTKLTKVTTEHPGRREAALRSIPIGRMGTPQDMAGAALFLASPLAAYVVGQTLIVDGG
LSLS
>Mature_244_residues
MNELDFSGKTVLVVGGSSGIGNGVAHAFRGRGAAVHVWGTRASAADYAGVEGSDLSDLAYAQVDVGDRAAIEAAEAIRPL
DVLVLCQGTVQYRRAEFEPEGWDRVMAVNLDSLMDCARKFRETLAERRGVVIVVSSVSGFQSNRGNPAYAASKAGAVSLT
KTLGEAWAPDGIRVVGLAPGLVDTKLTKVTTEHPGRREAALRSIPIGRMGTPQDMAGAALFLASPLAAYVVGQTLIVDGG
LSLS

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=249, Percent_Identity=32.5301204819277, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI32483357, Length=245, Percent_Identity=29.3877551020408, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI40254992, Length=244, Percent_Identity=31.5573770491803, Blast_Score=88, Evalue=6e-18,
Organism=Homo sapiens, GI5031737, Length=243, Percent_Identity=29.2181069958848, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI7705925, Length=243, Percent_Identity=28.8065843621399, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI126723750, Length=248, Percent_Identity=29.0322580645161, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI66933014, Length=254, Percent_Identity=30.3149606299213, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI19923817, Length=255, Percent_Identity=26.6666666666667, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI10190704, Length=252, Percent_Identity=28.968253968254, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI4758504, Length=258, Percent_Identity=27.1317829457364, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI1787335, Length=251, Percent_Identity=35.0597609561753, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI87082160, Length=253, Percent_Identity=29.6442687747036, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1790717, Length=252, Percent_Identity=31.7460317460317, Blast_Score=97, Evalue=7e-22,
Organism=Escherichia coli, GI1786812, Length=259, Percent_Identity=30.8880308880309, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1789208, Length=177, Percent_Identity=34.4632768361582, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI87082100, Length=252, Percent_Identity=28.5714285714286, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787905, Length=247, Percent_Identity=31.9838056680162, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI2367365, Length=239, Percent_Identity=29.7071129707113, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789057, Length=158, Percent_Identity=31.0126582278481, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1789378, Length=253, Percent_Identity=26.8774703557312, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI2367175, Length=246, Percent_Identity=29.6747967479675, Blast_Score=65, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI25147288, Length=244, Percent_Identity=30.327868852459, Blast_Score=104, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17555706, Length=248, Percent_Identity=33.4677419354839, Blast_Score=101, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17561402, Length=253, Percent_Identity=28.8537549407115, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI72000259, Length=270, Percent_Identity=29.2592592592593, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17562990, Length=271, Percent_Identity=27.6752767527675, Blast_Score=87, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17563726, Length=267, Percent_Identity=27.3408239700375, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17560150, Length=270, Percent_Identity=27.4074074074074, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI193204405, Length=266, Percent_Identity=30.0751879699248, Blast_Score=84, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17538480, Length=266, Percent_Identity=30.4511278195489, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17562906, Length=269, Percent_Identity=30.1115241635688, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17560220, Length=270, Percent_Identity=28.1481481481481, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17562910, Length=272, Percent_Identity=29.0441176470588, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17562904, Length=263, Percent_Identity=28.1368821292776, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17551412, Length=265, Percent_Identity=28.6792452830189, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17560332, Length=262, Percent_Identity=28.6259541984733, Blast_Score=79, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17559104, Length=261, Percent_Identity=28.735632183908, Blast_Score=79, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17531453, Length=268, Percent_Identity=29.8507462686567, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17562908, Length=263, Percent_Identity=29.277566539924, Blast_Score=78, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17560676, Length=246, Percent_Identity=26.8292682926829, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI71994600, Length=145, Percent_Identity=33.1034482758621, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI115534694, Length=247, Percent_Identity=28.3400809716599, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17508651, Length=246, Percent_Identity=29.2682926829268, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17544670, Length=265, Percent_Identity=27.9245283018868, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17565030, Length=267, Percent_Identity=26.9662921348315, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17538182, Length=253, Percent_Identity=30.4347826086957, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71994604, Length=243, Percent_Identity=26.7489711934156, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17538486, Length=265, Percent_Identity=24.9056603773585, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI193207185, Length=147, Percent_Identity=31.2925170068027, Blast_Score=67, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6324126, Length=247, Percent_Identity=27.5303643724696, Blast_Score=80, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21355319, Length=246, Percent_Identity=32.1138211382114, Blast_Score=108, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24639444, Length=247, Percent_Identity=30.3643724696356, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24644339, Length=256, Percent_Identity=32.421875, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI23397609, Length=245, Percent_Identity=29.7959183673469, Blast_Score=88, Evalue=5e-18,
Organism=Drosophila melanogaster, GI21357041, Length=257, Percent_Identity=29.1828793774319, Blast_Score=78, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24643142, Length=242, Percent_Identity=27.6859504132231, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24644337, Length=258, Percent_Identity=31.7829457364341, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI28571526, Length=252, Percent_Identity=28.968253968254, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI17737361, Length=253, Percent_Identity=26.8774703557312, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 25411; Mature: 25411

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNELDFSGKTVLVVGGSSGIGNGVAHAFRGRGAAVHVWGTRASAADYAGVEGSDLSDLAY
CCCCCCCCCEEEEEECCCCCCHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCHHEE
AQVDVGDRAAIEAAEAIRPLDVLVLCQGTVQYRRAEFEPEGWDRVMAVNLDSLMDCARKF
EEECCCCHHHHHHHHHCCCCEEEEEECCCHHHHHCCCCCCCCCEEEEECHHHHHHHHHHH
RETLAERRGVVIVVSSVSGFQSNRGNPAYAASKAGAVSLTKTLGEAWAPDGIRVVGLAPG
HHHHHHCCCEEEEEECCCCCCCCCCCCCEECCCCCCCHHHHHHHHHCCCCCEEEEEECCC
LVDTKLTKVTTEHPGRREAALRSIPIGRMGTPQDMAGAALFLASPLAAYVVGQTLIVDGG
CCCCHHEEEECCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEECC
LSLS
CCCC
>Mature Secondary Structure
MNELDFSGKTVLVVGGSSGIGNGVAHAFRGRGAAVHVWGTRASAADYAGVEGSDLSDLAY
CCCCCCCCCEEEEEECCCCCCHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCHHEE
AQVDVGDRAAIEAAEAIRPLDVLVLCQGTVQYRRAEFEPEGWDRVMAVNLDSLMDCARKF
EEECCCCHHHHHHHHHCCCCEEEEEECCCHHHHHCCCCCCCCCEEEEECHHHHHHHHHHH
RETLAERRGVVIVVSSVSGFQSNRGNPAYAASKAGAVSLTKTLGEAWAPDGIRVVGLAPG
HHHHHHCCCEEEEEECCCCCCCCCCCCCEECCCCCCCHHHHHHHHHCCCCCEEEEEECCC
LVDTKLTKVTTEHPGRREAALRSIPIGRMGTPQDMAGAALFLASPLAAYVVGQTLIVDGG
CCCCHHEEEECCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEECC
LSLS
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]