BacMap

Definition	Phenylobacterium zucineum HLK1, complete genome.
Accession	NC_011144
Length	3,996,255

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The map label for this gene is fabG [H]

Identifier: 197104584

GI number: 197104584

Start: 1281729

End: 1282493

Strand: Reverse

Name: fabG [H]

Synonym: PHZ_c1118

Alternate gene names: 197104584

Gene position: 1282493-1281729 (Counterclockwise)

Preceding gene: 197104585

Following gene: 197104583

Centisome position: 32.09

GC content: 72.81

Gene sequence:

>765_bases
ATGACCAGCCGCTCGATCAAGGGCTCGGTCGCCCTCGTCACCGGCGCGGCCGGCGGCATGGGCAGGGCCACCGCCGAACT
CTTCGCCGCCGAGGGCGCGCACGTAGCCGTCACCGACGTCTCCGAGGCCGGGGCCCGCGCCGTCGCCGATGCGATCGAGG
CCGCCGGCGGAAGCGCCGAGGCCTGGGCGCTCGACGTCTCGGACCCACGGGCGATCCGCGAAGTCGTGGCGGCGATCGCC
GCCCGCTTCGGCGGTCTCGACATCGTCGTGAACAACGCCGGGATTTCTGCCTTTTCTCCCATAGATTCCGAGGACTACGA
CGACATCTGGAACCGCGCCGTCGGCGTTCTGCTCACCGCCCACCAGCGGATCATCCGCGCCGCCCTGCCCCACCTTCGCC
GCTCGCAGGCGCCGCGGATCGTCAACATCGCCTCCACCGAGGCCCTTGGCGCCACGTCGCGGGACAGTCCCTATGCGGCG
GCCAAGGCGGGCGTCACCGGCCTCACCCGCGCCCTCGCCGTCGAGCTCGGCCCCGAGGGGATCACCGTCAACTGCATCTG
CCCGGGTCCCATCCTCACCGGCATGACGGAAGGCCTTCCCGAGGCCGACCGCCAGACCTTCGCCAGGCGGCGCACGGCCC
TGCGCCGCTACGGGGCGCCCGAGGAGGTCGCCCACATGACGCTCAGCCTCTGCCTGCCGGCCGCCTCCTACGTCACCGGC
GCGACGATCCCGGTCGACGGCGGGCTGATGGCCCGGAACGCCTGA

Upstream 100 bases:

>100_bases
CGCCGCAGGACATGGCCGGCGCGGCCCTGTTCCTGGCCTCGCCGCTGGCGGCCTATGTCGTCGGCCAGACCCTCATCGTG
GACGGAGGCCTCTCGCTCTC

Downstream 100 bases:

>100_bases
GGTCCCGGCCCACCTTCCCGTCCGGACTTTCCGCCAGGACTGGTTTGCGCGCATCATGCCGGCGGACCCCGCGGAGCCGC
CCATGCGCTGGAGCCGACGC

Product: 3-oxoacyl-[ACP] reductase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 254; Mature: 253

Protein sequence:

>254_residues
MTSRSIKGSVALVTGAAGGMGRATAELFAAEGAHVAVTDVSEAGARAVADAIEAAGGSAEAWALDVSDPRAIREVVAAIA
ARFGGLDIVVNNAGISAFSPIDSEDYDDIWNRAVGVLLTAHQRIIRAALPHLRRSQAPRIVNIASTEALGATSRDSPYAA
AKAGVTGLTRALAVELGPEGITVNCICPGPILTGMTEGLPEADRQTFARRRTALRRYGAPEEVAHMTLSLCLPAASYVTG
ATIPVDGGLMARNA

Sequences:

>Translated_254_residues
MTSRSIKGSVALVTGAAGGMGRATAELFAAEGAHVAVTDVSEAGARAVADAIEAAGGSAEAWALDVSDPRAIREVVAAIA
ARFGGLDIVVNNAGISAFSPIDSEDYDDIWNRAVGVLLTAHQRIIRAALPHLRRSQAPRIVNIASTEALGATSRDSPYAA
AKAGVTGLTRALAVELGPEGITVNCICPGPILTGMTEGLPEADRQTFARRRTALRRYGAPEEVAHMTLSLCLPAASYVTG
ATIPVDGGLMARNA
>Mature_253_residues
TSRSIKGSVALVTGAAGGMGRATAELFAAEGAHVAVTDVSEAGARAVADAIEAAGGSAEAWALDVSDPRAIREVVAAIAA
RFGGLDIVVNNAGISAFSPIDSEDYDDIWNRAVGVLLTAHQRIIRAALPHLRRSQAPRIVNIASTEALGATSRDSPYAAA
KAGVTGLTRALAVELGPEGITVNCICPGPILTGMTEGLPEADRQTFARRRTALRRYGAPEEVAHMTLSLCLPAASYVTGA
TIPVDGGLMARNA

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=254, Percent_Identity=30.3149606299213, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI40254992, Length=245, Percent_Identity=32.2448979591837, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI15277342, Length=257, Percent_Identity=34.2412451361868, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI126723750, Length=257, Percent_Identity=28.4046692607004, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI10190704, Length=251, Percent_Identity=31.8725099601594, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI5031737, Length=240, Percent_Identity=29.1666666666667, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI66933014, Length=252, Percent_Identity=30.952380952381, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI4758504, Length=261, Percent_Identity=28.735632183908, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI19923817, Length=255, Percent_Identity=27.843137254902, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI31542939, Length=206, Percent_Identity=31.5533980582524, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI59889578, Length=228, Percent_Identity=33.3333333333333, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI210032110, Length=198, Percent_Identity=29.2929292929293, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI4504505, Length=242, Percent_Identity=33.4710743801653, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI83715985, Length=261, Percent_Identity=27.5862068965517, Blast_Score=84, Evalue=8e-17,
Organism=Homo sapiens, GI7705925, Length=250, Percent_Identity=27.2, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI126723191, Length=187, Percent_Identity=27.807486631016, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI40807363, Length=200, Percent_Identity=27.5, Blast_Score=81, Evalue=9e-16,
Organism=Homo sapiens, GI4503301, Length=248, Percent_Identity=28.6290322580645, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI142976729, Length=198, Percent_Identity=26.2626262626263, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI33667109, Length=188, Percent_Identity=27.6595744680851, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI224922801, Length=173, Percent_Identity=31.2138728323699, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI223718074, Length=246, Percent_Identity=28.0487804878049, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI40254986, Length=194, Percent_Identity=28.3505154639175, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI25282469, Length=224, Percent_Identity=27.6785714285714, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI7657478, Length=186, Percent_Identity=25.8064516129032, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI20149619, Length=230, Percent_Identity=26.5217391304348, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1787335, Length=245, Percent_Identity=37.5510204081633, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1790717, Length=247, Percent_Identity=31.9838056680162, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1787905, Length=245, Percent_Identity=32.6530612244898, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1788459, Length=251, Percent_Identity=33.0677290836653, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI87082100, Length=253, Percent_Identity=32.4110671936759, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI2367175, Length=246, Percent_Identity=34.9593495934959, Blast_Score=103, Evalue=8e-24,
Organism=Escherichia coli, GI87082160, Length=255, Percent_Identity=29.4117647058824, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1789208, Length=260, Percent_Identity=31.5384615384615, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1789378, Length=246, Percent_Identity=31.7073170731707, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI2367365, Length=247, Percent_Identity=31.9838056680162, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1789057, Length=260, Percent_Identity=30.7692307692308, Blast_Score=87, Evalue=8e-19,
Organism=Escherichia coli, GI1786812, Length=252, Percent_Identity=28.1746031746032, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787526, Length=206, Percent_Identity=30.0970873786408, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1786701, Length=210, Percent_Identity=29.0476190476191, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1787820, Length=189, Percent_Identity=29.1005291005291, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71994600, Length=252, Percent_Identity=33.7301587301587, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17562910, Length=255, Percent_Identity=32.156862745098, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI71994604, Length=250, Percent_Identity=33.6, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17555706, Length=251, Percent_Identity=32.6693227091633, Blast_Score=110, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI17562904, Length=253, Percent_Identity=31.6205533596838, Blast_Score=104, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17538480, Length=265, Percent_Identity=32.0754716981132, Blast_Score=104, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI25147288, Length=245, Percent_Identity=31.4285714285714, Blast_Score=104, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17560676, Length=257, Percent_Identity=29.9610894941634, Blast_Score=103, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI17560332, Length=257, Percent_Identity=32.6848249027237, Blast_Score=103, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI17559104, Length=260, Percent_Identity=33.0769230769231, Blast_Score=103, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI17561402, Length=255, Percent_Identity=30.9803921568627, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17560150, Length=255, Percent_Identity=30.9803921568627, Blast_Score=98, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17538182, Length=258, Percent_Identity=31.3953488372093, Blast_Score=97, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17551412, Length=261, Percent_Identity=32.9501915708812, Blast_Score=97, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI17562906, Length=261, Percent_Identity=30.2681992337165, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI193204405, Length=266, Percent_Identity=30.8270676691729, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17563726, Length=255, Percent_Identity=28.2352941176471, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI72000259, Length=255, Percent_Identity=28.2352941176471, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17562990, Length=255, Percent_Identity=30.9803921568627, Blast_Score=94, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17564282, Length=257, Percent_Identity=28.4046692607004, Blast_Score=94, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17562908, Length=272, Percent_Identity=31.9852941176471, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI193203115, Length=198, Percent_Identity=29.7979797979798, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17567345, Length=191, Percent_Identity=29.8429319371728, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI193203117, Length=197, Percent_Identity=29.9492385786802, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17536651, Length=261, Percent_Identity=29.1187739463602, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17536025, Length=262, Percent_Identity=29.7709923664122, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17560220, Length=260, Percent_Identity=29.2307692307692, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17508895, Length=189, Percent_Identity=28.5714285714286, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17544670, Length=262, Percent_Identity=27.0992366412214, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17538486, Length=259, Percent_Identity=31.2741312741313, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17565030, Length=256, Percent_Identity=30.46875, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI115534694, Length=243, Percent_Identity=30.4526748971193, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17568967, Length=198, Percent_Identity=31.8181818181818, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17531453, Length=262, Percent_Identity=28.2442748091603, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17561272, Length=257, Percent_Identity=31.1284046692607, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI71982365, Length=196, Percent_Identity=29.0816326530612, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17508651, Length=261, Percent_Identity=27.5862068965517, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17558628, Length=194, Percent_Identity=29.3814432989691, Blast_Score=67, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6324126, Length=254, Percent_Identity=29.1338582677165, Blast_Score=97, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6322861, Length=196, Percent_Identity=33.1632653061224, Blast_Score=94, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24639444, Length=254, Percent_Identity=35.4330708661417, Blast_Score=120, Evalue=6e-28,
Organism=Drosophila melanogaster, GI23397609, Length=254, Percent_Identity=31.8897637795276, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI21355319, Length=252, Percent_Identity=28.968253968254, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI21357041, Length=253, Percent_Identity=32.8063241106719, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI28571526, Length=254, Percent_Identity=33.4645669291339, Blast_Score=104, Evalue=6e-23,
Organism=Drosophila melanogaster, GI24644339, Length=250, Percent_Identity=31.6, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI17737361, Length=257, Percent_Identity=30.7392996108949, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24581726, Length=216, Percent_Identity=29.6296296296296, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24644337, Length=252, Percent_Identity=34.1269841269841, Blast_Score=93, Evalue=1e-19,
Organism=Drosophila melanogaster, GI18859837, Length=245, Percent_Identity=34.6938775510204, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24643142, Length=249, Percent_Identity=30.5220883534137, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI21357673, Length=219, Percent_Identity=31.5068493150685, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24665243, Length=217, Percent_Identity=30.8755760368664, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24665247, Length=218, Percent_Identity=31.1926605504587, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24649181, Length=195, Percent_Identity=28.7179487179487, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24640492, Length=199, Percent_Identity=29.1457286432161, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24584744, Length=220, Percent_Identity=30.4545454545455, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI28574402, Length=220, Percent_Identity=30.4545454545455, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI221331218, Length=214, Percent_Identity=30.8411214953271, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI221510726, Length=200, Percent_Identity=29, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI281364892, Length=266, Percent_Identity=26.6917293233083, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI221331216, Length=215, Percent_Identity=31.1627906976744, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI161076933, Length=196, Percent_Identity=29.5918367346939, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24584748, Length=196, Percent_Identity=29.5918367346939, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21355631, Length=177, Percent_Identity=27.1186440677966, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 26054; Mature: 25923

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSRSIKGSVALVTGAAGGMGRATAELFAAEGAHVAVTDVSEAGARAVADAIEAAGGSAE
CCCCCCCCCEEEEEECCCCCCHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHCCCCCC
AWALDVSDPRAIREVVAAIAARFGGLDIVVNNAGISAFSPIDSEDYDDIWNRAVGVLLTA
EEEEECCCHHHHHHHHHHHHHHHCCEEEEEECCCCCEECCCCCCCHHHHHHHHHHHHHHH
HQRIIRAALPHLRRSQAPRIVNIASTEALGATSRDSPYAAAKAGVTGLTRALAVELGPEG
HHHHHHHHHHHHHHHCCCCEEEECCCHHCCCCCCCCCCHHHHHCHHHHHHHHHHEECCCC
ITVNCICPGPILTGMTEGLPEADRQTFARRRTALRRYGAPEEVAHMTLSLCLPAASYVTG
EEEEEEECCHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCC
ATIPVDGGLMARNA
CCEECCCCEECCCC
>Mature Secondary Structure 
TSRSIKGSVALVTGAAGGMGRATAELFAAEGAHVAVTDVSEAGARAVADAIEAAGGSAE
CCCCCCCCEEEEEECCCCCCHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHCCCCCC
AWALDVSDPRAIREVVAAIAARFGGLDIVVNNAGISAFSPIDSEDYDDIWNRAVGVLLTA
EEEEECCCHHHHHHHHHHHHHHHCCEEEEEECCCCCEECCCCCCCHHHHHHHHHHHHHHH
HQRIIRAALPHLRRSQAPRIVNIASTEALGATSRDSPYAAAKAGVTGLTRALAVELGPEG
HHHHHHHHHHHHHHHCCCCEEEECCCHHCCCCCCCCCCHHHHHCHHHHHHHHHHEECCCC
ITVNCICPGPILTGMTEGLPEADRQTFARRRTALRRYGAPEEVAHMTLSLCLPAASYVTG
EEEEEEECCHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCC
ATIPVDGGLMARNA
CCEECCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]