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The map label for this gene is fcs [H]

Identifier: 197104034

GI number: 197104034

Start: 602411

End: 604186

Strand: Reverse

Name: fcs [H]

Synonym: PHZ_c0568

Alternate gene names: 197104034

Gene position: 604186-602411 (Counterclockwise)

Preceding gene: 197104035

Following gene: 197104033

Centisome position: 15.12

GC content: 72.58

Gene sequence:

>1776_bases
ATGGACGCCGAGCTCAGCCTCTCCACCGCCCCGTTCCGCGATCCGCGCTATGCGCCGCGACGCCTGGAGATCGACCGCCG
CGGCGGCGGCGAGATGGTGCTGACCAATCCGACGCCCTATTCCACCCAGCACCAGACCACGACCTCGGCCCTGGACGCCT
GGGCCGCCAGCGCGCCCGACCGCGTCTGGCTGGCCGAGCGCTCGGGCGAGGGCTGGCGCACCCTGACGTTCGCCGAAGCG
CGCGAGCGGATCGCCGCGCTGGCGGGGGGTCTCAGGGAGCTGGGCGTCGTCGGTGAGCGGCCGCTGCTGATCCTGGCCCG
CAACGGCATAGACCACGCGCTGATCGCCTATGCGGCCATGAGCCAGGGCATGCCGGTCGCGCCCGTCTCGCCGCAGTACG
GCCTGCCCGGCGCGAACCTCGCCCGCCTGACCCACGCCGCCGAGATCCTGCAGCCCGCCGCCGTCTACACCGAGGACGCG
GCGCTGTTCGCCGACGGCCTCTCGGCCGAGATCCTGGCCGGCCTGCCGGTGATCGCGGGCCTGTCGCCGCGGGCCGGCGA
CATCCCGATGGAACGGCTCTACGAAGCCTCGGCCGCCACGTTCTGCGCCCGCCCGGAAGACCACGCCAAGTACCTGCTGA
CCTCGGGCTCGACCGGCCTGCCCAAGGCGGTGATCGGCCGTCACCGAGAGCTCAGCCTCAACGCGGCGCAGATCGCCGCG
TGCTTCGACGACCCCGACCCGCCGGTGATGCTGCACTCCGCCCCGTGGAGCCACAGCCTGGGCGCCAACGCCATCCTGCA
CATGAGCCTGCACCGGGGCGGGACGCTCTACATCGACGCCGGCCAGCCCACCGCGGCGAGGTTCGGCGAGACCCTGCGCA
ACCTGCGCGAGGTGCAGCCCACCTATCAGAACATGGTCCCCGCCGGCTGGATGCTGCTGGTCGACGAGCTGGAGAAGGAC
GAGGCGCTGGCCCGCAACTTCTTCTCGCGCGTGCGCCTGCTGCAGTACGGCGGCGCGGCCCTCGGCCAGACGGTCGCCGA
CCGCATCCAGGCCGTGGCGATCCGCACGGTGGGCGAGAAGATCAGCTTCTCCAGCGGCTATGGCGCTACCGAGACGGGTC
CGACCGCCTGCAACGTCCACTGGACCAACGGCCGCATGGGCATGATCGGCCTGCCCCTGCCCGGCACCTCGGTGCGGCTG
GTGCCGCAGGACGGGAAGCTCGACTTCCGGGTGAAGGGTCCGCAGGTGACCAGCGGCTACCTCGGCCGGCCCGACCTTTC
GGCCGCCGCCTTCGACGACGAGGGCTTCTACCGGCTGGGGGACGCCGCCCGCTTCGTCGATCCCGGGGATCCGGCGCAGG
GCATGATCTTCGACGGCCGGCTGTCCGAGAACTTCAAGCTGGCCTCGGGCACCTTCGTGACCGTCGGCGACCTGCGCATC
CGGGCGATCGGGGCGATCGGCGGGGCGGTGACCGACGCGGTGGTCTGCGGCGAGGGCGAGGAGGGGGTCGGCCTGCTGCT
CTATCCCAACCCCAACCTCTCGCATGCCGAGGTCGTCGCCGCCGCGCGCGACGGGCTGGCGCGGTTCAACGCCCAGGCGC
AGGGCGGCGGCAGGATCGCCCGCGCCCTCGTGCTTCCCGAGCCGCCGGACCCCCATTCCGGCGAGATCACCGACAAGGGC
TACATCGCCCAGAGCCTCGCCCGCGCGAAACACGCGGCCGCCGTCCGGCGGCTCTTCGCCCACCCGACACCTCCCGACGT
GATGGAGTTCGCATGA

Upstream 100 bases:

>100_bases
GCGCCCGCCGAGCGGCTGTACCTCCAACGACGGCTGCGCGAGCTGGAGAAGGCCTAGCGGGGCTCGACTTACGTCGCGGC
GGCCCGTAACCGATGGCCCC

Downstream 100 bases:

>100_bases
ACGGCGCCGACGCCCTGATCTCGACCCTGGTGGCCAACGAGGTCACCGCCTGCTTCGCCAATCCCGGCACCAGCGAGATG
CAGTTCGTGGCCGCGCTGGA

Product: feruloyl-CoA synthase

Products: NA

Alternate protein names: Long-chain acyl-CoA synthetase [H]

Number of amino acids: Translated: 591; Mature: 591

Protein sequence:

>591_residues
MDAELSLSTAPFRDPRYAPRRLEIDRRGGGEMVLTNPTPYSTQHQTTTSALDAWAASAPDRVWLAERSGEGWRTLTFAEA
RERIAALAGGLRELGVVGERPLLILARNGIDHALIAYAAMSQGMPVAPVSPQYGLPGANLARLTHAAEILQPAAVYTEDA
ALFADGLSAEILAGLPVIAGLSPRAGDIPMERLYEASAATFCARPEDHAKYLLTSGSTGLPKAVIGRHRELSLNAAQIAA
CFDDPDPPVMLHSAPWSHSLGANAILHMSLHRGGTLYIDAGQPTAARFGETLRNLREVQPTYQNMVPAGWMLLVDELEKD
EALARNFFSRVRLLQYGGAALGQTVADRIQAVAIRTVGEKISFSSGYGATETGPTACNVHWTNGRMGMIGLPLPGTSVRL
VPQDGKLDFRVKGPQVTSGYLGRPDLSAAAFDDEGFYRLGDAARFVDPGDPAQGMIFDGRLSENFKLASGTFVTVGDLRI
RAIGAIGGAVTDAVVCGEGEEGVGLLLYPNPNLSHAEVVAAARDGLARFNAQAQGGGRIARALVLPEPPDPHSGEITDKG
YIAQSLARAKHAAAVRRLFAHPTPPDVMEFA

Sequences:

>Translated_591_residues
MDAELSLSTAPFRDPRYAPRRLEIDRRGGGEMVLTNPTPYSTQHQTTTSALDAWAASAPDRVWLAERSGEGWRTLTFAEA
RERIAALAGGLRELGVVGERPLLILARNGIDHALIAYAAMSQGMPVAPVSPQYGLPGANLARLTHAAEILQPAAVYTEDA
ALFADGLSAEILAGLPVIAGLSPRAGDIPMERLYEASAATFCARPEDHAKYLLTSGSTGLPKAVIGRHRELSLNAAQIAA
CFDDPDPPVMLHSAPWSHSLGANAILHMSLHRGGTLYIDAGQPTAARFGETLRNLREVQPTYQNMVPAGWMLLVDELEKD
EALARNFFSRVRLLQYGGAALGQTVADRIQAVAIRTVGEKISFSSGYGATETGPTACNVHWTNGRMGMIGLPLPGTSVRL
VPQDGKLDFRVKGPQVTSGYLGRPDLSAAAFDDEGFYRLGDAARFVDPGDPAQGMIFDGRLSENFKLASGTFVTVGDLRI
RAIGAIGGAVTDAVVCGEGEEGVGLLLYPNPNLSHAEVVAAARDGLARFNAQAQGGGRIARALVLPEPPDPHSGEITDKG
YIAQSLARAKHAAAVRRLFAHPTPPDVMEFA
>Mature_591_residues
MDAELSLSTAPFRDPRYAPRRLEIDRRGGGEMVLTNPTPYSTQHQTTTSALDAWAASAPDRVWLAERSGEGWRTLTFAEA
RERIAALAGGLRELGVVGERPLLILARNGIDHALIAYAAMSQGMPVAPVSPQYGLPGANLARLTHAAEILQPAAVYTEDA
ALFADGLSAEILAGLPVIAGLSPRAGDIPMERLYEASAATFCARPEDHAKYLLTSGSTGLPKAVIGRHRELSLNAAQIAA
CFDDPDPPVMLHSAPWSHSLGANAILHMSLHRGGTLYIDAGQPTAARFGETLRNLREVQPTYQNMVPAGWMLLVDELEKD
EALARNFFSRVRLLQYGGAALGQTVADRIQAVAIRTVGEKISFSSGYGATETGPTACNVHWTNGRMGMIGLPLPGTSVRL
VPQDGKLDFRVKGPQVTSGYLGRPDLSAAAFDDEGFYRLGDAARFVDPGDPAQGMIFDGRLSENFKLASGTFVTVGDLRI
RAIGAIGGAVTDAVVCGEGEEGVGLLLYPNPNLSHAEVVAAARDGLARFNAQAQGGGRIARALVLPEPPDPHSGEITDKG
YIAQSLARAKHAAAVRRLFAHPTPPDVMEFA

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: COG0318

COG function: function code IQ; Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II

Gene ontology:

Cell location: Partially Membrane-Associated [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent AMP-binding enzyme family [H]

Homologues:

Organism=Escherichia coli, GI1788107, Length=266, Percent_Identity=27.4436090225564, Blast_Score=73, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI32563687, Length=407, Percent_Identity=24.0786240786241, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI18859661, Length=405, Percent_Identity=25.4320987654321, Blast_Score=72, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020459
- InterPro:   IPR020845
- InterPro:   IPR000873 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.3 [H]

Molecular weight: Translated: 62813; Mature: 62813

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAELSLSTAPFRDPRYAPRRLEIDRRGGGEMVLTNPTPYSTQHQTTTSALDAWAASAPD
CCCCCCCCCCCCCCCCCCCCEEEEECCCCCCEEEECCCCCCCCCCHHHHHHHHHHCCCCC
RVWLAERSGEGWRTLTFAEARERIAALAGGLRELGVVGERPLLILARNGIDHALIAYAAM
EEEEEECCCCCCEEEEHHHHHHHHHHHHCCHHHHCCCCCCCEEEEECCCCCHHHHHHHHH
SQGMPVAPVSPQYGLPGANLARLTHAAEILQPAAVYTEDAALFADGLSAEILAGLPVIAG
HCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHEECCHHHHHCCCCHHHHHCCHHHCC
LSPRAGDIPMERLYEASAATFCARPEDHAKYLLTSGSTGLPKAVIGRHRELSLNAAQIAA
CCCCCCCCCHHHHHHHHHHHEECCCCHHCEEEEECCCCCCCHHHHCCCCEEECCHHHEEE
CFDDPDPPVMLHSAPWSHSLGANAILHMSLHRGGTLYIDAGQPTAARFGETLRNLREVQP
ECCCCCCCEEEECCCCCCCCCCCEEEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHCH
TYQNMVPAGWMLLVDELEKDEALARNFFSRVRLLQYGGAALGQTVADRIQAVAIRTVGEK
HHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCC
ISFSSGYGATETGPTACNVHWTNGRMGMIGLPLPGTSVRLVPQDGKLDFRVKGPQVTSGY
EECCCCCCCCCCCCCEEEEEECCCCEEEEEECCCCCEEEEEECCCCEEEEECCCEECCCC
LGRPDLSAAAFDDEGFYRLGDAARFVDPGDPAQGMIFDGRLSENFKLASGTFVTVGDLRI
CCCCCCCCEEECCCCCEEECCCCCCCCCCCCCCCEEEECCCCCCEEEECCCEEEECCEEE
RAIGAIGGAVTDAVVCGEGEEGVGLLLYPNPNLSHAEVVAAARDGLARFNAQAQGGGRIA
EEEEHHCHHHHHEEEECCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEE
RALVLPEPPDPHSGEITDKGYIAQSLARAKHAAAVRRLFAHPTPPDVMEFA
EEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCC
>Mature Secondary Structure
MDAELSLSTAPFRDPRYAPRRLEIDRRGGGEMVLTNPTPYSTQHQTTTSALDAWAASAPD
CCCCCCCCCCCCCCCCCCCCEEEEECCCCCCEEEECCCCCCCCCCHHHHHHHHHHCCCCC
RVWLAERSGEGWRTLTFAEARERIAALAGGLRELGVVGERPLLILARNGIDHALIAYAAM
EEEEEECCCCCCEEEEHHHHHHHHHHHHCCHHHHCCCCCCCEEEEECCCCCHHHHHHHHH
SQGMPVAPVSPQYGLPGANLARLTHAAEILQPAAVYTEDAALFADGLSAEILAGLPVIAG
HCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHEECCHHHHHCCCCHHHHHCCHHHCC
LSPRAGDIPMERLYEASAATFCARPEDHAKYLLTSGSTGLPKAVIGRHRELSLNAAQIAA
CCCCCCCCCHHHHHHHHHHHEECCCCHHCEEEEECCCCCCCHHHHCCCCEEECCHHHEEE
CFDDPDPPVMLHSAPWSHSLGANAILHMSLHRGGTLYIDAGQPTAARFGETLRNLREVQP
ECCCCCCCEEEECCCCCCCCCCCEEEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHCH
TYQNMVPAGWMLLVDELEKDEALARNFFSRVRLLQYGGAALGQTVADRIQAVAIRTVGEK
HHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCC
ISFSSGYGATETGPTACNVHWTNGRMGMIGLPLPGTSVRLVPQDGKLDFRVKGPQVTSGY
EECCCCCCCCCCCCCEEEEEECCCCEEEEEECCCCCEEEEEECCCCEEEEECCCEECCCC
LGRPDLSAAAFDDEGFYRLGDAARFVDPGDPAQGMIFDGRLSENFKLASGTFVTVGDLRI
CCCCCCCCEEECCCCCEEECCCCCCCCCCCCCCCEEEECCCCCCEEEECCCEEEECCEEE
RAIGAIGGAVTDAVVCGEGEEGVGLLLYPNPNLSHAEVVAAARDGLARFNAQAQGGGRIA
EEEEHHCHHHHHEEEECCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEE
RALVLPEPPDPHSGEITDKGYIAQSLARAKHAAAVRRLFAHPTPPDVMEFA
EEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]