| Definition | Phenylobacterium zucineum HLK1, complete genome. |
|---|---|
| Accession | NC_011144 |
| Length | 3,996,255 |
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The map label for this gene is ilvX [H]
Identifier: 197104033
GI number: 197104033
Start: 600873
End: 602414
Strand: Reverse
Name: ilvX [H]
Synonym: PHZ_c0567
Alternate gene names: 197104033
Gene position: 602414-600873 (Counterclockwise)
Preceding gene: 197104034
Following gene: 197104024
Centisome position: 15.07
GC content: 72.76
Gene sequence:
>1542_bases ATGAACGGCGCCGACGCCCTGATCTCGACCCTGGTGGCCAACGAGGTCACCGCCTGCTTCGCCAATCCCGGCACCAGCGA GATGCAGTTCGTGGCCGCGCTGGACGGCGTGCCGCAGATGCGGCCGGTGCTGTGCCAGTTCGAAGGCGTGGCCACGGGCG CGGCCGACGGCTACGGCCGGATCGCGGACCGGCCGGCCTGCACCCTGCTGCACCTCGGGCCCGGCTACGGCAACGGCGTC GCCAACCTGCACAACGCCCGCCGGGCCTATACGCCGATCGTCAACGTGATCGGCGACCACGCCACCTATCACCGCCAGTA CGACGCGCCGCTGAACTCCGACATCGCCACCCTGGTGAAGCCGAACTCGATCTGGGTGAAGTCGGCCGAGACCGCCGACG ATGTCTCGGCGCTCGCGGCCGAGGCCGTGCAGGCCTCGTACGGTCCGCCCGGCGGTCCGGTCAGCCTGATCCTCCCGGCC GACAGCGCCTGGCTGCCGGCCGGCGGCGAGATCGCCCGCGCCCAGCGGCCGGCGCGCGCGGCGCCCCGCGGCGAGGCGGT CGAGGCCGCCGCCCGCGCGCTGAAGGCGGCGAAGAACCCCGTGATCCTGCTGGGCAATCAGGCCTGCCGCGCCGAGGCGC TGAAGGAGGCCGCCCGGCTGCAGGCGGCGGGGATCACCATCTATTCCGACACCTTCGTGCCCCGCCAGCCGCGCGGCGCC GGCGTGTTCGCGCCCAAGAAGATGCCCTACTTCGGCGAGATGGCCCTGGGCGAGCTCGAGGGCGTCGACCTGATGGTGTT CGTCGGCACGACGACGCCGGTGGCCTTCTTCGCCTATCCCAACCGGCCCAGCGTCCTCGTCCCCGAGGGGTGCCAGACCC TCACCCTCGCGGACCGGGCCGAGGATTCGGTCGCCGGCCTCGCCGCCCTGGCCGATGCGCTGGGGGCGCCCAAGGAAGGG CCGGTCCAGGCGCTGGCCCTGCCGGACGCCGCGCCCAGCGGGGGCCTCAATCCCTACTACGTGGGAACGTCCATCGCCCG GCACATGCCCGAGAACGCCATCGTCTGCGACGATGCGGTGACCTCCGGCACCGGCGTGGCGGCCATGACGGCGAGCGCCC GGCCGCACGAGGTGCTGGCGCTGACCGGCGGGGCGATCGGCATCGGCCTGCCGCTCGCCATCGGCGCGGCCGTCGCCGCG CCCGACCGCAAGGTGCTCAGCCTGAACGGCGACGGGGCGGCGATGTATACGGTCCAGGCGCTCTGGACGATGGCCCGCGA GAACCTCGACATCACCGTCGTGGTGTTCGCCAACTACACCTACCGCATCCTCAACGTGGAGATGACCCGCACCGGCGCCG GCGAGGCGGGCCCCTCGGCGCGCAAGCTGCTCGACCTGGGCGATCCGAAGATCGACTGGGTCCCGATCGCCAAGGGCATG GGCCTGCCGGCGGTGAGCTGCGCCACCGCCGAGGAGTTCGACAAGGCCTTCGCCGCCGCCATGGCCCAGAAGGGCCCGAC CTTCATCGAGGCGGTGATCTAG
Upstream 100 bases:
>100_bases ACAAGGGCTACATCGCCCAGAGCCTCGCCCGCGCGAAACACGCGGCCGCCGTCCGGCGGCTCTTCGCCCACCCGACACCT CCCGACGTGATGGAGTTCGC
Downstream 100 bases:
>100_bases CCTCCTGTCCGGCAGGAGAACGGCCCAAGGAAAAAGGCCCGCGGATCGCTCCGCGGGCCTTCGTCTTTTCAGCCTTGCCG GCCGATCACTTGTTGCCGGG
Product: hypothetical protein
Products: NA
Alternate protein names: ALS; Acetohydroxy-acid synthase large subunit; AHAS [H]
Number of amino acids: Translated: 513; Mature: 513
Protein sequence:
>513_residues MNGADALISTLVANEVTACFANPGTSEMQFVAALDGVPQMRPVLCQFEGVATGAADGYGRIADRPACTLLHLGPGYGNGV ANLHNARRAYTPIVNVIGDHATYHRQYDAPLNSDIATLVKPNSIWVKSAETADDVSALAAEAVQASYGPPGGPVSLILPA DSAWLPAGGEIARAQRPARAAPRGEAVEAAARALKAAKNPVILLGNQACRAEALKEAARLQAAGITIYSDTFVPRQPRGA GVFAPKKMPYFGEMALGELEGVDLMVFVGTTTPVAFFAYPNRPSVLVPEGCQTLTLADRAEDSVAGLAALADALGAPKEG PVQALALPDAAPSGGLNPYYVGTSIARHMPENAIVCDDAVTSGTGVAAMTASARPHEVLALTGGAIGIGLPLAIGAAVAA PDRKVLSLNGDGAAMYTVQALWTMARENLDITVVVFANYTYRILNVEMTRTGAGEAGPSARKLLDLGDPKIDWVPIAKGM GLPAVSCATAEEFDKAFAAAMAQKGPTFIEAVI
Sequences:
>Translated_513_residues MNGADALISTLVANEVTACFANPGTSEMQFVAALDGVPQMRPVLCQFEGVATGAADGYGRIADRPACTLLHLGPGYGNGV ANLHNARRAYTPIVNVIGDHATYHRQYDAPLNSDIATLVKPNSIWVKSAETADDVSALAAEAVQASYGPPGGPVSLILPA DSAWLPAGGEIARAQRPARAAPRGEAVEAAARALKAAKNPVILLGNQACRAEALKEAARLQAAGITIYSDTFVPRQPRGA GVFAPKKMPYFGEMALGELEGVDLMVFVGTTTPVAFFAYPNRPSVLVPEGCQTLTLADRAEDSVAGLAALADALGAPKEG PVQALALPDAAPSGGLNPYYVGTSIARHMPENAIVCDDAVTSGTGVAAMTASARPHEVLALTGGAIGIGLPLAIGAAVAA PDRKVLSLNGDGAAMYTVQALWTMARENLDITVVVFANYTYRILNVEMTRTGAGEAGPSARKLLDLGDPKIDWVPIAKGM GLPAVSCATAEEFDKAFAAAMAQKGPTFIEAVI >Mature_513_residues MNGADALISTLVANEVTACFANPGTSEMQFVAALDGVPQMRPVLCQFEGVATGAADGYGRIADRPACTLLHLGPGYGNGV ANLHNARRAYTPIVNVIGDHATYHRQYDAPLNSDIATLVKPNSIWVKSAETADDVSALAAEAVQASYGPPGGPVSLILPA DSAWLPAGGEIARAQRPARAAPRGEAVEAAARALKAAKNPVILLGNQACRAEALKEAARLQAAGITIYSDTFVPRQPRGA GVFAPKKMPYFGEMALGELEGVDLMVFVGTTTPVAFFAYPNRPSVLVPEGCQTLTLADRAEDSVAGLAALADALGAPKEG PVQALALPDAAPSGGLNPYYVGTSIARHMPENAIVCDDAVTSGTGVAAMTASARPHEVLALTGGAIGIGLPLAIGAAVAA PDRKVLSLNGDGAAMYTVQALWTMARENLDITVVVFANYTYRILNVEMTRTGAGEAGPSARKLLDLGDPKIDWVPIAKGM GLPAVSCATAEEFDKAFAAAMAQKGPTFIEAVI
Specific function: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine [H]
COG id: COG0028
COG function: function code EH; Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the TPP enzyme family [H]
Homologues:
Organism=Escherichia coli, GI1790104, Length=551, Percent_Identity=25.5898366606171, Blast_Score=94, Evalue=2e-20, Organism=Escherichia coli, GI87081685, Length=235, Percent_Identity=28.5106382978723, Blast_Score=63, Evalue=4e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012001 - InterPro: IPR011766 [H]
Pfam domain/function: PF02775 TPP_enzyme_C; PF02776 TPP_enzyme_N [H]
EC number: =2.2.1.6 [H]
Molecular weight: Translated: 52879; Mature: 52879
Theoretical pI: Translated: 4.94; Mature: 4.94
Prosite motif: PS00187 TPP_ENZYMES
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.4 %Cys (Translated Protein) 2.5 %Met (Translated Protein) 3.9 %Cys+Met (Translated Protein) 1.4 %Cys (Mature Protein) 2.5 %Met (Mature Protein) 3.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNGADALISTLVANEVTACFANPGTSEMQFVAALDGVPQMRPVLCQFEGVATGAADGYGR CCHHHHHHHHHHHHHHHEEECCCCCCCEEEEEHHCCCCCCCHHHEEECCCCCCCCCCCCC IADRPACTLLHLGPGYGNGVANLHNARRAYTPIVNVIGDHATYHRQYDAPLNSDIATLVK CCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHCEECCCCCCCCCEEEEC PNSIWVKSAETADDVSALAAEAVQASYGPPGGPVSLILPADSAWLPAGGEIARAQRPARA CCCEEEECCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCHHHHCCCCCC APRGEAVEAAARALKAAKNPVILLGNQACRAEALKEAARLQAAGITIYSDTFVPRQPRGA CCCCHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCC GVFAPKKMPYFGEMALGELEGVDLMVFVGTTTPVAFFAYPNRPSVLVPEGCQTLTLADRA CCCCCCCCCCCCCHHHCCCCCCEEEEEEECCCCEEEEEECCCCCEECCCCCCEEEEHHCC EDSVAGLAALADALGAPKEGPVQALALPDAAPSGGLNPYYVGTSIARHMPENAIVCDDAV CHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCEEECHHHHHHCCCCCEEECCCC TSGTGVAAMTASARPHEVLALTGGAIGIGLPLAIGAAVAAPDRKVLSLNGDGAAMYTVQA CCCCCEEEEECCCCCCEEEEEECCCCEECHHHHHHHHHCCCCCEEEEECCCCCEEHHHHH LWTMARENLDITVVVFANYTYRILNVEMTRTGAGEAGPSARKLLDLGDPKIDWVPIAKGM HHHHHHCCCCEEEEEEECCEEEEEEEEEEECCCCCCCCHHHHHHHCCCCCEEEEEECCCC GLPAVSCATAEEFDKAFAAAMAQKGPTFIEAVI CCCCEECCCHHHHHHHHHHHHHHCCCCEEEEEC >Mature Secondary Structure MNGADALISTLVANEVTACFANPGTSEMQFVAALDGVPQMRPVLCQFEGVATGAADGYGR CCHHHHHHHHHHHHHHHEEECCCCCCCEEEEEHHCCCCCCCHHHEEECCCCCCCCCCCCC IADRPACTLLHLGPGYGNGVANLHNARRAYTPIVNVIGDHATYHRQYDAPLNSDIATLVK CCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHCEECCCCCCCCCEEEEC PNSIWVKSAETADDVSALAAEAVQASYGPPGGPVSLILPADSAWLPAGGEIARAQRPARA CCCEEEECCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCHHHHCCCCCC APRGEAVEAAARALKAAKNPVILLGNQACRAEALKEAARLQAAGITIYSDTFVPRQPRGA CCCCHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCC GVFAPKKMPYFGEMALGELEGVDLMVFVGTTTPVAFFAYPNRPSVLVPEGCQTLTLADRA CCCCCCCCCCCCCHHHCCCCCCEEEEEEECCCCEEEEEECCCCCEECCCCCCEEEEHHCC EDSVAGLAALADALGAPKEGPVQALALPDAAPSGGLNPYYVGTSIARHMPENAIVCDDAV CHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCEEECHHHHHHCCCCCEEECCCC TSGTGVAAMTASARPHEVLALTGGAIGIGLPLAIGAAVAAPDRKVLSLNGDGAAMYTVQA CCCCCEEEEECCCCCCEEEEEECCCCEECHHHHHHHHHCCCCCEEEEECCCCCEEHHHHH LWTMARENLDITVVVFANYTYRILNVEMTRTGAGEAGPSARKLLDLGDPKIDWVPIAKGM HHHHHHCCCCEEEEEEECCEEEEEEEEEEECCCCCCCCHHHHHHHCCCCCEEEEEECCCC GLPAVSCATAEEFDKAFAAAMAQKGPTFIEAVI CCCCEECCCHHHHHHHHHHHHHHCCCCEEEEEC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9634230 [H]