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The map label for this gene is 197104020

Identifier: 197104020

GI number: 197104020

Start: 586103

End: 586585

Strand: Direct

Name: 197104020

Synonym: PHZ_c0554

Alternate gene names: NA

Gene position: 586103-586585 (Clockwise)

Preceding gene: 197104018

Following gene: 197104022

Centisome position: 14.67

GC content: 67.08

Gene sequence:

>483_bases
ATGACCATCAAAGTCGGCGACAAGCTGCCCAACGTCACCCTCACCCAGGCCACGGCCGAGGGCCCGCGTCCGGTCTCCAG
CGAAGAGTTCTTCAAGGGCAAGACGGTGGCGCTGTTCGCGGTGCCGGGCGCCTTCACCCCGACCTGCTCGGCCAAGCACC
TGCCCGGCTTCAAGCAGGAGGCCGGCGCGCTGAAGGGCAAGGGCGTCGACGAGATCGCCTGCCTGTCGGTGAACGACGCC
TTCGTGATGCGCGCCTGGGCCGAGGACCAGGCGGTGGGCGAGGACATCACCATGCTGGCCGACGGCAACGGCGACTTCAC
CAAGGCCATCGGCCTGGAGATGGACGGCTCCAAGTTCGGGATGGGGCCGCGCTCGCAGCGCTATTCGATGATCGTCGAGG
ACGGGGTCGTGAAGCAGCTCAACGTCGAGCAGGGCGGGGAATTCAAGGTCTCGTCCGCCGACTACCTGCTGGCGCAGCTC
TAG

Upstream 100 bases:

>100_bases
CAGGAACCCGCTTTCCATCGTCTGCGAATGTCGAGCCTCTTCGTGGCGCTTTCAAGGAGGTTCGGCTATCAGCGGAATGA
AAGCCCATTGGAGGACGGAC

Downstream 100 bases:

>100_bases
GCGCGCTCGGAAAGGGCCGGCTCACGAAGCGGGAGCCGGCCTCGCCGAAGCGCCAGGGCTTCTCCGCGGCCTTGGTGATG
CCGATCCGCGGGCCGACCGC

Product: peroxiredoxin

Products: NA

Alternate protein names: Thioredoxin reductase [H]

Number of amino acids: Translated: 160; Mature: 159

Protein sequence:

>160_residues
MTIKVGDKLPNVTLTQATAEGPRPVSSEEFFKGKTVALFAVPGAFTPTCSAKHLPGFKQEAGALKGKGVDEIACLSVNDA
FVMRAWAEDQAVGEDITMLADGNGDFTKAIGLEMDGSKFGMGPRSQRYSMIVEDGVVKQLNVEQGGEFKVSSADYLLAQL

Sequences:

>Translated_160_residues
MTIKVGDKLPNVTLTQATAEGPRPVSSEEFFKGKTVALFAVPGAFTPTCSAKHLPGFKQEAGALKGKGVDEIACLSVNDA
FVMRAWAEDQAVGEDITMLADGNGDFTKAIGLEMDGSKFGMGPRSQRYSMIVEDGVVKQLNVEQGGEFKVSSADYLLAQL
>Mature_159_residues
TIKVGDKLPNVTLTQATAEGPRPVSSEEFFKGKTVALFAVPGAFTPTCSAKHLPGFKQEAGALKGKGVDEIACLSVNDAF
VMRAWAEDQAVGEDITMLADGNGDFTKAIGLEMDGSKFGMGPRSQRYSMIVEDGVVKQLNVEQGGEFKVSSADYLLAQL

Specific function: Unknown

COG id: COG0678

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutaredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI6912238, Length=161, Percent_Identity=46.583850931677, Blast_Score=127, Evalue=4e-30,
Organism=Saccharomyces cerevisiae, GI6323138, Length=167, Percent_Identity=31.1377245508982, Blast_Score=73, Evalue=2e-14,
Organism=Drosophila melanogaster, GI78706776, Length=145, Percent_Identity=47.5862068965517, Blast_Score=131, Evalue=2e-31,
Organism=Drosophila melanogaster, GI78709078, Length=145, Percent_Identity=47.5862068965517, Blast_Score=131, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011767
- InterPro:   IPR002109
- InterPro:   IPR011906
- InterPro:   IPR014025
- InterPro:   IPR013740
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00462 Glutaredoxin; PF08534 Redoxin [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 16994; Mature: 16862

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIKVGDKLPNVTLTQATAEGPRPVSSEEFFKGKTVALFAVPGAFTPTCSAKHLPGFKQE
CEEECCCCCCCEEEEECCCCCCCCCCCCHHHCCCEEEEEEECCCCCCCCCCCCCCCCCHH
AGALKGKGVDEIACLSVNDAFVMRAWAEDQAVGEDITMLADGNGDFTKAIGLEMDGSKFG
CCCCCCCCCCEEEEEEECCCEEEEECCCCCCCCCCEEEEECCCCCEEEEECEEECCCCCC
MGPRSQRYSMIVEDGVVKQLNVEQGGEFKVSSADYLLAQL
CCCCCCCEEEEECCCCEEEECCCCCCCEEECCCCEEEECC
>Mature Secondary Structure 
TIKVGDKLPNVTLTQATAEGPRPVSSEEFFKGKTVALFAVPGAFTPTCSAKHLPGFKQE
EEECCCCCCCEEEEECCCCCCCCCCCCHHHCCCEEEEEEECCCCCCCCCCCCCCCCCHH
AGALKGKGVDEIACLSVNDAFVMRAWAEDQAVGEDITMLADGNGDFTKAIGLEMDGSKFG
CCCCCCCCCCEEEEEEECCCEEEEECCCCCCCCCCEEEEECCCCCEEEEECEEECCCCCC
MGPRSQRYSMIVEDGVVKQLNVEQGGEFKVSSADYLLAQL
CCCCCCCEEEEECCCCEEEECCCCCCCEEECCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]