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The map label for this gene is obgE

Identifier: 197103720

GI number: 197103720

Start: 254500

End: 255540

Strand: Reverse

Name: obgE

Synonym: PHZ_c0254

Alternate gene names: 197103720

Gene position: 255540-254500 (Counterclockwise)

Preceding gene: 197103721

Following gene: 197103719

Centisome position: 6.39

GC content: 71.47

Gene sequence:

>1041_bases
ATGAAGTTCCTCGACCAGGTGAAGATCTACGTCCGCTCGGGCAACGGCGGCGCCGGCGCCGTCTCGTTCCGGCGCGAGAA
GTACATCGAGTACGGCGGCCCCGACGGCGGCGACGGCGGCCGCGGCGGCGACGTGTGGATCGAGGCGGTCGAGGGCCTCA
ACACCCTGATCGACTACCGCTACCAGCAGCACTTCAAGGCCGGCACCGGCGTCCACGGCATGGGCCGCAACCGCCACGGC
GCGGCGGGCGAGGACGTGGTGCTGAAGGTCCCCGTGGGCACCGAGGTGCTGGACGAGGACAAGAACCTGATCGTCGACAT
GGACGAGGCGGGCAAGCGCTACCTGCTGGCCAAGGGCGGCAACGGCGGCTTCGGCAACACCCACTTCAAGGGCCCGGTGA
ACCAGGCCCCGCGCCACGCCAACCCCGGCCTGCCCGGCGAGGAGCGCGCCATCTGGCTGCGCCTGAAGCTGATCGCCGAC
GTGGGCCTGGTCGGCCTGCCGAACGCCGGCAAGTCGACCTTCCTGGCCGCCGCCAGCGCCGCCAAGCCGAAGATCGCCGA
CTATCCCTTCACCACCCTGGCCCCCAACCTCGGCGTTGTGGACCTGTCCGTGGGCGAACGCTTCGTCCTGGCCGACATCC
CTGGCCTCATCGAGGGCGCCCACGAGGGGGCCGGCATCGGCACCCGCTTCCTGGGCCACATCGAGCGCACCGCCGTGCTG
ATCCACCTGGTGGACGGCACGCAGGAGGACATCGTCGGCGCGTGGAGGACGGTCCGCCACGAGCTGGAGGCCTATGGCGC
GGACCTGGCCGACAAGCCCGAGATCCTGGCGCTGAACAAGATCGACGCCCTGGACGAGGAGACCCGCGCCGAGAAGCAGG
CGCAGCTGGCGGAGGCCGCGGGGATGGACGTGCGCCTCGTCTCGGGCTTCACCGGCGAGAACGTCACCGAGCTGCTGCGC
GAGGCCTTCGCCCTGGTGCGCGAGCGCAAGCGCGCGGCGGCCGAAGAGGCGGCGGGGCCCTCCGAGGGCTGGACGCCGTG
A

Upstream 100 bases:

>100_bases
CCTTCCTGCCGGGCGCGGCCCTCAAGTCGCTCGCCGCGGCGGGCCTCGTCCGCCTCGTGGCGCTGGCCCTCGCCCGCCAC
GCCGCGCTAAGGGCTGACGC

Downstream 100 bases:

>100_bases
GCGGCCTCGGGCAGGCCCGGCGCGTCGTCGTCAAGGTGGGCTCGGCCCTGCTGGTGGGGCCGGACGGCGCCCCGCACGCG
GACTGGCTCGCCGACTTCGC

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MKFLDQVKIYVRSGNGGAGAVSFRREKYIEYGGPDGGDGGRGGDVWIEAVEGLNTLIDYRYQQHFKAGTGVHGMGRNRHG
AAGEDVVLKVPVGTEVLDEDKNLIVDMDEAGKRYLLAKGGNGGFGNTHFKGPVNQAPRHANPGLPGEERAIWLRLKLIAD
VGLVGLPNAGKSTFLAAASAAKPKIADYPFTTLAPNLGVVDLSVGERFVLADIPGLIEGAHEGAGIGTRFLGHIERTAVL
IHLVDGTQEDIVGAWRTVRHELEAYGADLADKPEILALNKIDALDEETRAEKQAQLAEAAGMDVRLVSGFTGENVTELLR
EAFALVRERKRAAAEEAAGPSEGWTP

Sequences:

>Translated_346_residues
MKFLDQVKIYVRSGNGGAGAVSFRREKYIEYGGPDGGDGGRGGDVWIEAVEGLNTLIDYRYQQHFKAGTGVHGMGRNRHG
AAGEDVVLKVPVGTEVLDEDKNLIVDMDEAGKRYLLAKGGNGGFGNTHFKGPVNQAPRHANPGLPGEERAIWLRLKLIAD
VGLVGLPNAGKSTFLAAASAAKPKIADYPFTTLAPNLGVVDLSVGERFVLADIPGLIEGAHEGAGIGTRFLGHIERTAVL
IHLVDGTQEDIVGAWRTVRHELEAYGADLADKPEILALNKIDALDEETRAEKQAQLAEAAGMDVRLVSGFTGENVTELLR
EAFALVRERKRAAAEEAAGPSEGWTP
>Mature_346_residues
MKFLDQVKIYVRSGNGGAGAVSFRREKYIEYGGPDGGDGGRGGDVWIEAVEGLNTLIDYRYQQHFKAGTGVHGMGRNRHG
AAGEDVVLKVPVGTEVLDEDKNLIVDMDEAGKRYLLAKGGNGGFGNTHFKGPVNQAPRHANPGLPGEERAIWLRLKLIAD
VGLVGLPNAGKSTFLAAASAAKPKIADYPFTTLAPNLGVVDLSVGERFVLADIPGLIEGAHEGAGIGTRFLGHIERTAVL
IHLVDGTQEDIVGAWRTVRHELEAYGADLADKPEILALNKIDALDEETRAEKQAQLAEAAGMDVRLVSGFTGENVTELLR
EAFALVRERKRAAAEEAAGPSEGWTP

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain

Homologues:

Organism=Homo sapiens, GI24308117, Length=320, Percent_Identity=40.625, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI111955139, Length=306, Percent_Identity=40.8496732026144, Blast_Score=179, Evalue=4e-45,
Organism=Homo sapiens, GI111955063, Length=146, Percent_Identity=45.2054794520548, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI4557537, Length=119, Percent_Identity=38.655462184874, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI4758796, Length=124, Percent_Identity=36.2903225806452, Blast_Score=69, Evalue=5e-12,
Organism=Escherichia coli, GI1789574, Length=350, Percent_Identity=53.1428571428571, Blast_Score=305, Evalue=4e-84,
Organism=Escherichia coli, GI1787454, Length=106, Percent_Identity=34.9056603773585, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17508313, Length=280, Percent_Identity=39.6428571428571, Blast_Score=152, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI17552324, Length=318, Percent_Identity=33.3333333333333, Blast_Score=136, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17509631, Length=123, Percent_Identity=33.3333333333333, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71981008, Length=115, Percent_Identity=34.7826086956522, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17555344, Length=115, Percent_Identity=35.6521739130435, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6321962, Length=166, Percent_Identity=39.1566265060241, Blast_Score=115, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24585318, Length=291, Percent_Identity=39.1752577319588, Blast_Score=166, Evalue=2e-41,
Organism=Drosophila melanogaster, GI20129375, Length=321, Percent_Identity=36.4485981308411, Blast_Score=152, Evalue=3e-37,
Organism=Drosophila melanogaster, GI17981711, Length=115, Percent_Identity=38.2608695652174, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OBG_PHEZH (B4RD64)

Other databases:

- EMBL:   CP000747
- RefSeq:   YP_002129097.1
- GeneID:   6789744
- GenomeReviews:   CP000747_GR
- KEGG:   pzu:PHZ_c0254
- HOGENOM:   HBG716038
- OMA:   ATCEHAG
- ProtClustDB:   PRK12299
- GO:   GO:0005737
- HAMAP:   MF_01454
- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:2.70.210.12
- PANTHER:   PTHR11702:SF3
- PIRSF:   PIRSF002401
- PRINTS:   PR00326
- TIGRFAMs:   TIGR02729
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1; SSF82051 GTP1_OBG_sub

EC number: NA

Molecular weight: Translated: 36920; Mature: 36920

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: PS00905 GTP1_OBG; PS00213 LIPOCALIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFLDQVKIYVRSGNGGAGAVSFRREKYIEYGGPDGGDGGRGGDVWIEAVEGLNTLIDYR
CCCHHEEEEEEEECCCCCCEEHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
YQQHFKAGTGVHGMGRNRHGAAGEDVVLKVPVGTEVLDEDKNLIVDMDEAGKRYLLAKGG
HHHHHCCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHCCCCCEEEEECCCCCEEEEEECC
NGGFGNTHFKGPVNQAPRHANPGLPGEERAIWLRLKLIADVGLVGLPNAGKSTFLAAASA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEHHCCCEEECCCCCCCCEEEHHCC
AKPKIADYPFTTLAPNLGVVDLSVGERFVLADIPGLIEGAHEGAGIGTRFLGHIERTAVL
CCCCCCCCCHHHHCCCCCEEEECCCCEEEEECCCHHHHCCCCCCCHHHHHHHHHHHEEEE
IHLVDGTQEDIVGAWRTVRHELEAYGADLADKPEILALNKIDALDEETRAEKQAQLAEAA
EEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCHHHCCHHHHHHHHHHHHHHC
GMDVRLVSGFTGENVTELLREAFALVRERKRAAAEEAAGPSEGWTP
CCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MKFLDQVKIYVRSGNGGAGAVSFRREKYIEYGGPDGGDGGRGGDVWIEAVEGLNTLIDYR
CCCHHEEEEEEEECCCCCCEEHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
YQQHFKAGTGVHGMGRNRHGAAGEDVVLKVPVGTEVLDEDKNLIVDMDEAGKRYLLAKGG
HHHHHCCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHCCCCCEEEEECCCCCEEEEEECC
NGGFGNTHFKGPVNQAPRHANPGLPGEERAIWLRLKLIADVGLVGLPNAGKSTFLAAASA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEHHCCCEEECCCCCCCCEEEHHCC
AKPKIADYPFTTLAPNLGVVDLSVGERFVLADIPGLIEGAHEGAGIGTRFLGHIERTAVL
CCCCCCCCCHHHHCCCCCEEEECCCCEEEEECCCHHHHCCCCCCCHHHHHHHHHHHEEEE
IHLVDGTQEDIVGAWRTVRHELEAYGADLADKPEILALNKIDALDEETRAEKQAQLAEAA
EEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCHHHCCHHHHHHHHHHHHHHC
GMDVRLVSGFTGENVTELLREAFALVRERKRAAAEEAAGPSEGWTP
CCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA