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The map label for this gene is aroA

Identifier: 197103654

GI number: 197103654

Start: 181766

End: 183124

Strand: Direct

Name: aroA

Synonym: PHZ_c0188

Alternate gene names: 197103654

Gene position: 181766-183124 (Clockwise)

Preceding gene: 197103647

Following gene: 197103655

Centisome position: 4.55

GC content: 75.06

Gene sequence:

>1359_bases
ATGACGGCGGCCCACCTGACCGCCAGGCGCGCGGGGTCCCTCAAGGGGACCGTGCGGGCCCCGGGGGACAAATCCATCAG
CCACCGCGCGCTCATCCTGGGCGCGCTCGCCAGCGGCCTGACCGAGGTCGACGGCCTGCTCGAGAGCGACGACGTGCGCC
GCACCGCGGCCGCCATGCAGGCGTTCGGCGCGGGCGTGATCCGCACCGGCGAGGGCGCCTGGCGCGTCGAGGGCAAGGGC
GGGTTCGCCGAGCCGGGCGACGTGATCGACTGCGGCAACGCCGGCACCGGCGTGCGGCTGATCATGGGCGCGGCGGCGGG
CTTCGACCTGGCGGCGACCTTCACGGGCGACAGCTCGCTGCGCGGCCGGCCGATGAATCGGGTGCTGAAGCCGCTGGGCG
AGATGGGGGCGAGCTGGATCTGCCGGGCCGGCGGGCGGCTGCCGCTGACGCTGAAGGGCGGGAGCCTGAAGCGCATCGCC
TACCGCCTGCCCGAGCCCTCGGCGCAGGTGAAGTCGGCCGTGCTGCTGGCGGGCCTGAGCGCCGACGGCGGCGCCGAGGT
GTTCGAGGCCGAGGCCACCCGCGACCACACCGAGCGGATGCTGCGCGGCTTCGGCGCCGAGGTGGACGTGACCGAAGAGA
GCGCGGGCCGGCGCATCGTGCTGCCCGGCGGCCAGGCGCTGAAGGGCACCCGGATCCGGGTGCCGGGCGACCCGTCGTCG
GCGGCCTTCCCGCTGGTCGCGGCGCTGGTCACGCCGGGCTCGCAGGTGACCGTCGAGGGCATGCTGCTCAATCCGCTGCG
CATCGGCCTTCTCGAGACGCTGGGCGACATGGGCGCGGACCTGTCGGTGACCAACGTGCGCGACGAGGGGGGCGAGACGG
TGGCCGACGTCACGGCCCGCCACTCCGCGCTGGAGGGCGTCGAGACGCCGCCCGAGCGGGCGCCGTCGATGATCGACGAA
TACCCGATCCTGGCCGTCGCCGCGGCCTTCGCCTCGGGCCGGACCGTGATGCGCGGCATCGGCGAGATGCGGGTGAAGGA
GAGCGACCGGATCGCCCTGATGGCCGCCGGCCTCGCCGCCTGCGGGGTCGAGGTGGAGGAGGAGCCCGAGGGGATGATCG
TCACGGGCCGCGGCGGCGCCGTGCGCGGCGGCGGGCGGATCACCACCCACGGCGACCACCGGATCGCCATGTCCCACCTC
GTGCTGGGCATGGCCGCCGAGGAGCCGGTGAGCGTGGACGAGCCCGGCATGATCGCCACCAGCTTCCCCGGCTTCGTCGA
GATGATGCGCGGCCTCGGAGCGGACGTGGGAGCGGACGTGGGAGGGGATGTGGGCGCGGACTCGCCGGTCGGCGCATGA

Upstream 100 bases:

>100_bases
TTGCTCGCGAAAAGCGGGCTCCCTTGCCACGCGCGAACGCCGCTGTCAAAGCAATCCCCCTCGTGATTTTGCGCTTATCC
CGGAGGCTCGTTTTCGGCAC

Downstream 100 bases:

>100_bases
GGGGCCCGTTCGTGATCACGGTCGACGGGCCGGCGGCCTCGGGCAAGGGCACGATCGCCAGCCGCCTGGCGCGGGAATAC
GACCTGCCGATGCTGGATTC

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS

Number of amino acids: Translated: 452; Mature: 451

Protein sequence:

>452_residues
MTAAHLTARRAGSLKGTVRAPGDKSISHRALILGALASGLTEVDGLLESDDVRRTAAAMQAFGAGVIRTGEGAWRVEGKG
GFAEPGDVIDCGNAGTGVRLIMGAAAGFDLAATFTGDSSLRGRPMNRVLKPLGEMGASWICRAGGRLPLTLKGGSLKRIA
YRLPEPSAQVKSAVLLAGLSADGGAEVFEAEATRDHTERMLRGFGAEVDVTEESAGRRIVLPGGQALKGTRIRVPGDPSS
AAFPLVAALVTPGSQVTVEGMLLNPLRIGLLETLGDMGADLSVTNVRDEGGETVADVTARHSALEGVETPPERAPSMIDE
YPILAVAAAFASGRTVMRGIGEMRVKESDRIALMAAGLAACGVEVEEEPEGMIVTGRGGAVRGGGRITTHGDHRIAMSHL
VLGMAAEEPVSVDEPGMIATSFPGFVEMMRGLGADVGADVGGDVGADSPVGA

Sequences:

>Translated_452_residues
MTAAHLTARRAGSLKGTVRAPGDKSISHRALILGALASGLTEVDGLLESDDVRRTAAAMQAFGAGVIRTGEGAWRVEGKG
GFAEPGDVIDCGNAGTGVRLIMGAAAGFDLAATFTGDSSLRGRPMNRVLKPLGEMGASWICRAGGRLPLTLKGGSLKRIA
YRLPEPSAQVKSAVLLAGLSADGGAEVFEAEATRDHTERMLRGFGAEVDVTEESAGRRIVLPGGQALKGTRIRVPGDPSS
AAFPLVAALVTPGSQVTVEGMLLNPLRIGLLETLGDMGADLSVTNVRDEGGETVADVTARHSALEGVETPPERAPSMIDE
YPILAVAAAFASGRTVMRGIGEMRVKESDRIALMAAGLAACGVEVEEEPEGMIVTGRGGAVRGGGRITTHGDHRIAMSHL
VLGMAAEEPVSVDEPGMIATSFPGFVEMMRGLGADVGADVGGDVGADSPVGA
>Mature_451_residues
TAAHLTARRAGSLKGTVRAPGDKSISHRALILGALASGLTEVDGLLESDDVRRTAAAMQAFGAGVIRTGEGAWRVEGKGG
FAEPGDVIDCGNAGTGVRLIMGAAAGFDLAATFTGDSSLRGRPMNRVLKPLGEMGASWICRAGGRLPLTLKGGSLKRIAY
RLPEPSAQVKSAVLLAGLSADGGAEVFEAEATRDHTERMLRGFGAEVDVTEESAGRRIVLPGGQALKGTRIRVPGDPSSA
AFPLVAALVTPGSQVTVEGMLLNPLRIGLLETLGDMGADLSVTNVRDEGGETVADVTARHSALEGVETPPERAPSMIDEY
PILAVAAAFASGRTVMRGIGEMRVKESDRIALMAAGLAACGVEVEEEPEGMIVTGRGGAVRGGGRITTHGDHRIAMSHLV
LGMAAEEPVSVDEPGMIATSFPGFVEMMRGLGADVGADVGGDVGADSPVGA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family

Homologues:

Organism=Escherichia coli, GI1787137, Length=439, Percent_Identity=29.3849658314351, Blast_Score=122, Evalue=6e-29,
Organism=Saccharomyces cerevisiae, GI6320332, Length=475, Percent_Identity=28, Blast_Score=113, Evalue=6e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROA_PHEZH (B4RCK3)

Other databases:

- EMBL:   CP000747
- RefSeq:   YP_002129031.1
- GeneID:   6789678
- GenomeReviews:   CP000747_GR
- KEGG:   pzu:PHZ_c0188
- HOGENOM:   HBG646626
- OMA:   LSRNHTE
- ProtClustDB:   PRK02427
- GO:   GO:0005737
- HAMAP:   MF_00210
- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792
- Gene3D:   G3DSA:3.65.10.10
- PIRSF:   PIRSF000505
- TIGRFAMs:   TIGR01356

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.19

Molecular weight: Translated: 46246; Mature: 46115

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS00104 EPSP_SYNTHASE_1; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAAHLTARRAGSLKGTVRAPGDKSISHRALILGALASGLTEVDGLLESDDVRRTAAAMQ
CCCHHHHHHHCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
AFGAGVIRTGEGAWRVEGKGGFAEPGDVIDCGNAGTGVRLIMGAAAGFDLAATFTGDSSL
HHCCCEEEECCCCEEEECCCCCCCCCCEEECCCCCCCEEEEEECCCCCCEEEEECCCCCC
RGRPMNRVLKPLGEMGASWICRAGGRLPLTLKGGSLKRIAYRLPEPSAQVKSAVLLAGLS
CCCCHHHHHHHHHHHCCCEEECCCCCEEEEECCCCEEEHEEECCCCHHHHHHEEEEEECC
ADGGAEVFEAEATRDHTERMLRGFGAEVDVTEESAGRRIVLPGGQALKGTRIRVPGDPSS
CCCCCCEEECHHHHHHHHHHHHHCCCCEEEECCCCCCEEEECCCCCCCCCEEECCCCCCC
AAFPLVAALVTPGSQVTVEGMLLNPLRIGLLETLGDMGADLSVTNVRDEGGETVADVTAR
HHHHHHHHHHCCCCCEEEEEEEECHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHH
HSALEGVETPPERAPSMIDEYPILAVAAAFASGRTVMRGIGEMRVKESDRIALMAAGLAA
HHHHCCCCCCHHHCHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEEHHHHH
CGVEVEEEPEGMIVTGRGGAVRGGGRITTHGDHRIAMSHLVLGMAAEEPVSVDEPGMIAT
CCCCCCCCCCCEEEECCCCEEECCCEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCEEEE
SFPGFVEMMRGLGADVGADVGGDVGADSPVGA
CCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TAAHLTARRAGSLKGTVRAPGDKSISHRALILGALASGLTEVDGLLESDDVRRTAAAMQ
CCHHHHHHHCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
AFGAGVIRTGEGAWRVEGKGGFAEPGDVIDCGNAGTGVRLIMGAAAGFDLAATFTGDSSL
HHCCCEEEECCCCEEEECCCCCCCCCCEEECCCCCCCEEEEEECCCCCCEEEEECCCCCC
RGRPMNRVLKPLGEMGASWICRAGGRLPLTLKGGSLKRIAYRLPEPSAQVKSAVLLAGLS
CCCCHHHHHHHHHHHCCCEEECCCCCEEEEECCCCEEEHEEECCCCHHHHHHEEEEEECC
ADGGAEVFEAEATRDHTERMLRGFGAEVDVTEESAGRRIVLPGGQALKGTRIRVPGDPSS
CCCCCCEEECHHHHHHHHHHHHHCCCCEEEECCCCCCEEEECCCCCCCCCEEECCCCCCC
AAFPLVAALVTPGSQVTVEGMLLNPLRIGLLETLGDMGADLSVTNVRDEGGETVADVTAR
HHHHHHHHHHCCCCCEEEEEEEECHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHH
HSALEGVETPPERAPSMIDEYPILAVAAAFASGRTVMRGIGEMRVKESDRIALMAAGLAA
HHHHCCCCCCHHHCHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEEHHHHH
CGVEVEEEPEGMIVTGRGGAVRGGGRITTHGDHRIAMSHLVLGMAAEEPVSVDEPGMIAT
CCCCCCCCCCCEEEECCCCEEECCCEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCEEEE
SFPGFVEMMRGLGADVGADVGGDVGADSPVGA
CCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA