Definition Streptococcus equi subsp. zooepidemicus MGCS10565, complete genome.
Accession NC_011134
Length 2,024,171

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The map label for this gene is abcA [H]

Identifier: 195977969

GI number: 195977969

Start: 884543

End: 885751

Strand: Direct

Name: abcA [H]

Synonym: Sez_0841

Alternate gene names: 195977969

Gene position: 884543-885751 (Clockwise)

Preceding gene: 195977968

Following gene: 195977970

Centisome position: 43.7

GC content: 42.6

Gene sequence:

>1209_bases
ATGGCTAATAAAGAAATTGCAGTAACAGTTGATCATGTCAGTAAGTCCTTTAAGCTGCCAACAGAGGCAACCAAGAGCTT
TCGTACTGCTCTTGTTAACCGATTTAAAGGCATTAAGGGCTATACCGAGCAGCATGTGCTAAGGGATATTAGCTTTGACG
TGTATAAGGGTGATTTTTTTGGCATCGTTGGACGAAATGGCTCTGGAAAATCAACCTTATTAAAAATTATTTCTCAAATT
TATGTTCCAGAAAAAGGACAGGTCACAGTTGAAGGGAAAATGGTGTCCTTCATCGAGCTTGGTGTTGGCTTTAATCCTGA
GTTGACTGGGCGTGAAAATGTCTACATGAATGGCGCGATGCTGGGCTTTACCACAGAAGAGGTTGACGATATGTATGATG
ATATCGTTGACTTTGCTGAGCTGCATGATTTCATGAATCAAAAATTAAAAAATTATTCCTCAGGCATGCAGGTTCGTCTT
GCCTTTTCTGTCGCTATCAAGGCACAGGGAGATGTGCTGATTCTTGATGAGGTGTTAGCTGTTGGTGATGAGGCCTTTCA
GCGAAAATGCAATGACTACTTCATGGAGCGCAAGGAGAGCGGCAAGACTACTATATTAGTGACTCATGACATGGGCGCTG
TCAAAAAATACTGCAATCGCGCAGTCCTCATCGAAAATGGTCTTGTCAAGGCTTATGGTGAGCCCTTTGATGTTGCTAAC
CAATACAGTGTTGATAATACTGAATTGAAAAATGATGAGCAAGGAGCTGTTGCTGAGCCTGTGTCTGGTTTGGCAAGCCA
GCTAGAAGTGAGATTGACCTCTAAGCCAAGCCTTAGTCCAGATGAGCCCATTTCCTTTGAGATTTCCTATCATGTCCTAA
AGGACGAGCCTACCTATGTTGCCTTTTCGTTGACTGATATTGACCGCAATATTTGGGTATATAATGACAATTCACAGGAT
CAGCCGACAAGTGGTCCTGGTCATAAGAACATATCCTACCAGTGTCAGCTCTCACAGCTAAATGATATCAAATTAAAGCT
TGAGGTGACTGTTCGCGATCAAAATGGGCAAATGCTGCTTTTTTCAGCAGCTAATCATTCTCCACTAATCGTGCTTCAAC
GACATGATATTGCTCCAGATGACCTGTCTGCTTTGGACTCAGCCAGCGGCTTATATCAAAGAAATGGCAGCTGGCTCATT
AATCAATAA

Upstream 100 bases:

>100_bases
GGTGCTATATCATCATTCCTTACCTCATTCCATTTGTCCTATTAGCACTTGGGGTAGCAGTGTTTAATAAAAATGCTAAG
AAGTTTGCGGAGATTATCTA

Downstream 100 bases:

>100_bases
TCGTCATTAGAAAGCATCATATGAAAAAAGTTTCCATTATTTGCACCAATTATAATAAGGGGCCTTGGATCGCAGAGGCC
TTAGACAGCTTTTTAGCCCA

Product: ABC-transporter ATP-binding protein

Products: ADP; phosphate; putrescine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 402; Mature: 401

Protein sequence:

>402_residues
MANKEIAVTVDHVSKSFKLPTEATKSFRTALVNRFKGIKGYTEQHVLRDISFDVYKGDFFGIVGRNGSGKSTLLKIISQI
YVPEKGQVTVEGKMVSFIELGVGFNPELTGRENVYMNGAMLGFTTEEVDDMYDDIVDFAELHDFMNQKLKNYSSGMQVRL
AFSVAIKAQGDVLILDEVLAVGDEAFQRKCNDYFMERKESGKTTILVTHDMGAVKKYCNRAVLIENGLVKAYGEPFDVAN
QYSVDNTELKNDEQGAVAEPVSGLASQLEVRLTSKPSLSPDEPISFEISYHVLKDEPTYVAFSLTDIDRNIWVYNDNSQD
QPTSGPGHKNISYQCQLSQLNDIKLKLEVTVRDQNGQMLLFSAANHSPLIVLQRHDIAPDDLSALDSASGLYQRNGSWLI
NQ

Sequences:

>Translated_402_residues
MANKEIAVTVDHVSKSFKLPTEATKSFRTALVNRFKGIKGYTEQHVLRDISFDVYKGDFFGIVGRNGSGKSTLLKIISQI
YVPEKGQVTVEGKMVSFIELGVGFNPELTGRENVYMNGAMLGFTTEEVDDMYDDIVDFAELHDFMNQKLKNYSSGMQVRL
AFSVAIKAQGDVLILDEVLAVGDEAFQRKCNDYFMERKESGKTTILVTHDMGAVKKYCNRAVLIENGLVKAYGEPFDVAN
QYSVDNTELKNDEQGAVAEPVSGLASQLEVRLTSKPSLSPDEPISFEISYHVLKDEPTYVAFSLTDIDRNIWVYNDNSQD
QPTSGPGHKNISYQCQLSQLNDIKLKLEVTVRDQNGQMLLFSAANHSPLIVLQRHDIAPDDLSALDSASGLYQRNGSWLI
NQ
>Mature_401_residues
ANKEIAVTVDHVSKSFKLPTEATKSFRTALVNRFKGIKGYTEQHVLRDISFDVYKGDFFGIVGRNGSGKSTLLKIISQIY
VPEKGQVTVEGKMVSFIELGVGFNPELTGRENVYMNGAMLGFTTEEVDDMYDDIVDFAELHDFMNQKLKNYSSGMQVRLA
FSVAIKAQGDVLILDEVLAVGDEAFQRKCNDYFMERKESGKTTILVTHDMGAVKKYCNRAVLIENGLVKAYGEPFDVANQ
YSVDNTELKNDEQGAVAEPVSGLASQLEVRLTSKPSLSPDEPISFEISYHVLKDEPTYVAFSLTDIDRNIWVYNDNSQDQ
PTSGPGHKNISYQCQLSQLNDIKLKLEVTVRDQNGQMLLFSAANHSPLIVLQRHDIAPDDLSALDSASGLYQRNGSWLIN
Q

Specific function: Influences the expression of the surface array protein gene (vapA). May have both regulatory and transport activities [H]

COG id: COG1134

COG function: function code GM; ABC-type polysaccharide/polyol phosphate transport system, ATPase component

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI31657092, Length=211, Percent_Identity=25.1184834123223, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI116734710, Length=214, Percent_Identity=24.7663551401869, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI153792144, Length=228, Percent_Identity=26.3157894736842, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI47078218, Length=235, Percent_Identity=26.3829787234043, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI45446740, Length=235, Percent_Identity=26.3829787234043, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI150417984, Length=218, Percent_Identity=28.4403669724771, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI27477115, Length=211, Percent_Identity=27.9620853080569, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI27436953, Length=218, Percent_Identity=26.605504587156, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI6005701, Length=194, Percent_Identity=26.2886597938144, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI105990541, Length=191, Percent_Identity=24.6073298429319, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI27262624, Length=252, Percent_Identity=23.015873015873, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI27262626, Length=252, Percent_Identity=23.015873015873, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI30795238, Length=219, Percent_Identity=22.8310502283105, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI21536376, Length=204, Percent_Identity=25.4901960784314, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI27881501, Length=219, Percent_Identity=22.8310502283105, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI87081791, Length=298, Percent_Identity=22.1476510067114, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1790467, Length=211, Percent_Identity=27.9620853080569, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1789032, Length=216, Percent_Identity=22.2222222222222, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787029, Length=217, Percent_Identity=26.7281105990783, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1786398, Length=205, Percent_Identity=25.8536585365854, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787089, Length=213, Percent_Identity=23.943661971831, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790525, Length=293, Percent_Identity=24.5733788395904, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1786319, Length=194, Percent_Identity=27.319587628866, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87081709, Length=214, Percent_Identity=23.8317757009346, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI87081782, Length=216, Percent_Identity=25.462962962963, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1788450, Length=222, Percent_Identity=24.3243243243243, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI48995001, Length=209, Percent_Identity=25.3588516746411, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1787370, Length=211, Percent_Identity=22.7488151658768, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI48994943, Length=211, Percent_Identity=23.2227488151659, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1786703, Length=206, Percent_Identity=27.6699029126214, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1788210, Length=139, Percent_Identity=31.6546762589928, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788761, Length=212, Percent_Identity=23.1132075471698, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788225, Length=224, Percent_Identity=24.5535714285714, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI87082267, Length=205, Percent_Identity=23.4146341463415, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1789593, Length=231, Percent_Identity=24.6753246753247, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1788540, Length=212, Percent_Identity=26.4150943396226, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1786803, Length=228, Percent_Identity=22.3684210526316, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1787712, Length=246, Percent_Identity=23.1707317073171, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789751, Length=229, Percent_Identity=24.0174672489083, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788897, Length=209, Percent_Identity=24.8803827751196, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17510237, Length=213, Percent_Identity=24.8826291079812, Blast_Score=85, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI115533608, Length=210, Percent_Identity=25.2380952380952, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17565586, Length=233, Percent_Identity=24.4635193133047, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71992290, Length=207, Percent_Identity=27.0531400966184, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71983516, Length=212, Percent_Identity=23.5849056603774, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71983510, Length=212, Percent_Identity=23.5849056603774, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71983523, Length=212, Percent_Identity=23.5849056603774, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17533971, Length=208, Percent_Identity=28.8461538461538, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17565938, Length=206, Percent_Identity=26.2135922330097, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI193209708, Length=209, Percent_Identity=27.2727272727273, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI193202349, Length=190, Percent_Identity=26.8421052631579, Blast_Score=65, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6321720, Length=239, Percent_Identity=24.6861924686192, Blast_Score=64, Evalue=4e-11,
Organism=Drosophila melanogaster, GI116007184, Length=192, Percent_Identity=23.9583333333333, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI221500365, Length=192, Percent_Identity=23.9583333333333, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24582014, Length=271, Percent_Identity=25.0922509225092, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24582012, Length=271, Percent_Identity=25.0922509225092, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI221512771, Length=218, Percent_Identity=24.7706422018349, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24666092, Length=297, Percent_Identity=23.5690235690236, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24643674, Length=217, Percent_Identity=24.4239631336406, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI28573571, Length=216, Percent_Identity=24.537037037037, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI28573573, Length=207, Percent_Identity=24.1545893719807, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI281362751, Length=203, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI281363262, Length=226, Percent_Identity=26.5486725663717, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24650853, Length=201, Percent_Identity=27.363184079602, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24653245, Length=226, Percent_Identity=26.5486725663717, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24650855, Length=201, Percent_Identity=27.363184079602, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI85725262, Length=292, Percent_Identity=24.3150684931507, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24659289, Length=198, Percent_Identity=28.2828282828283, Blast_Score=68, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24648314, Length=208, Percent_Identity=23.0769230769231, Blast_Score=65, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 44812; Mature: 44681

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MANKEIAVTVDHVSKSFKLPTEATKSFRTALVNRFKGIKGYTEQHVLRDISFDVYKGDFF
CCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCEEECCCEE
GIVGRNGSGKSTLLKIISQIYVPEKGQVTVEGKMVSFIELGVGFNPELTGRENVYMNGAM
EEEECCCCCHHHHHHHHHHHCCCCCCCEEECCEEEEEEEECCCCCCCCCCCCCEEECCEE
LGFTTEEVDDMYDDIVDFAELHDFMNQKLKNYSSGMQVRLAFSVAIKAQGDVLILDEVLA
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCEEEEHHHHH
VGDEAFQRKCNDYFMERKESGKTTILVTHDMGAVKKYCNRAVLIENGLVKAYGEPFDVAN
CCCHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHCCCEEEEECCCCEECCCCCCCCC
QYSVDNTELKNDEQGAVAEPVSGLASQLEVRLTSKPSLSPDEPISFEISYHVLKDEPTYV
CCCCCCCCCCCCCCCCHHHHHHHHHHHEEEEEECCCCCCCCCCEEEEEEEEEEECCCCEE
AFSLTDIDRNIWVYNDNSQDQPTSGPGHKNISYQCQLSQLNDIKLKLEVTVRDQNGQMLL
EEEEEECCCEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEEEEEECCCCCEEE
FSAANHSPLIVLQRHDIAPDDLSALDSASGLYQRNGSWLINQ
EEECCCCCEEEEEECCCCCCHHHHHHHCCCCEECCCCEEECC
>Mature Secondary Structure 
ANKEIAVTVDHVSKSFKLPTEATKSFRTALVNRFKGIKGYTEQHVLRDISFDVYKGDFF
CCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCEEECCCEE
GIVGRNGSGKSTLLKIISQIYVPEKGQVTVEGKMVSFIELGVGFNPELTGRENVYMNGAM
EEEECCCCCHHHHHHHHHHHCCCCCCCEEECCEEEEEEEECCCCCCCCCCCCCEEECCEE
LGFTTEEVDDMYDDIVDFAELHDFMNQKLKNYSSGMQVRLAFSVAIKAQGDVLILDEVLA
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCEEEEHHHHH
VGDEAFQRKCNDYFMERKESGKTTILVTHDMGAVKKYCNRAVLIENGLVKAYGEPFDVAN
CCCHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHCCCEEEEECCCCEECCCCCCCCC
QYSVDNTELKNDEQGAVAEPVSGLASQLEVRLTSKPSLSPDEPISFEISYHVLKDEPTYV
CCCCCCCCCCCCCCCCHHHHHHHHHHHEEEEEECCCCCCCCCCEEEEEEEEEEECCCCEE
AFSLTDIDRNIWVYNDNSQDQPTSGPGHKNISYQCQLSQLNDIKLKLEVTVRDQNGQMLL
EEEEEECCCEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEEEEEECCCCCEEE
FSAANHSPLIVLQRHDIAPDDLSALDSASGLYQRNGSWLINQ
EEECCCCCEEEEEECCCCCCHHHHHHHCCCCEECCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; putrescine [Periplasm]; H2O [C]

Specific reaction: ATP + putrescine [Periplasm] + H2O = ADP + phosphate + putrescine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8491726 [H]