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The map label for this gene is rbsK [H]

Identifier: 195977610

GI number: 195977610

Start: 490201

End: 491079

Strand: Direct

Name: rbsK [H]

Synonym: Sez_0469

Alternate gene names: 195977610

Gene position: 490201-491079 (Clockwise)

Preceding gene: 195977609

Following gene: 195977611

Centisome position: 24.22

GC content: 47.67

Gene sequence:

>879_bases
ATGGACCTTGTCATGGAAACTAAGCGGATTGCTAAGGAGGGCGAAACGGTCTTTGGAGAAGCCTTTTCTATGGTTCCTGG
TGGTAAAGGAGCCAATCAGGCTGTCGCTGTAGGACGGCTGAGCTTAGACAGTGATAGAATTACCATGTTAGGAGCTGTTG
GGCAGGATTCCTTTGGGCCACTCTTGCTTGACAACCTCAAAAAGAATGGTGTTTCTGTGGAGTATGTGGGAACGGTACCA
TTATCTAGTGGAATTGCCCAGATTACCATTTTCAATCATGATAATCGCATTATTTATTGCCCAGGGGCTAATGGTCAAGT
AGATACCAGGACATGGCAGGCGGAGTGGGAGGTGCTAGCGGCAGCAGACCTGGTGATCCTGCAAAATGAAATTCCCCATG
AGGCTAATCTGGCTATTGCTCGTTATTGTCATGAGCGTGGCATCAAGGTCCTCTACAATCCTGCACCAGCTCGTGAAACA
GACTTAGACCTGTTGACTTTTGTGGACTACGTTACCCCAAATGAGCATGAATGTCAGGATCTATTCCCAGAGCTGAGCCT
TGAAGAGGCTCTAAGGACCTATCCCAACAAGCTAATCGTGACACTCGGGATTAGGGGAGCTGCTTATTGTGATGGTAAGG
CTATTCATGTGATTCCAGCTATCAAGGCAGAGGCGGTTGATACCACTGGAGCAGGTGATACTTTTAATGGTGCCTTTGGT
CTTGCGATCTCACATGGGCTAAATACAGCGGCAGCCTTACGCTTTGCGACCTTGGCTTCTCACCTATCTGTCCAACAATT
TGGTGCCCAAGGGGGCATGCCAAGGCTAGAAGAAATGAAGGAGCATGAAGCATATGAAAAAGCATGGGATTTTAAATAG

Upstream 100 bases:

>100_bases
CCGATTGATGAAAAGCGTATAAAATTACCCGTTCACTATGTGGAACGCGAAACAATAAGGAGAAAGCATGAGTAATATTG
TGATTATTGGTAGCATTTCT

Downstream 100 bases:

>100_bases
CGATGTAGCTAAGTTGGCTGCCGATTTAGGACATACTGATCGTGTCTGCATTGGAGATTTGGGGCTGCCGGTTCCTGTAG
GAGTCCCGAAGATTGATCTG

Product: ribokinase RbsK

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MDLVMETKRIAKEGETVFGEAFSMVPGGKGANQAVAVGRLSLDSDRITMLGAVGQDSFGPLLLDNLKKNGVSVEYVGTVP
LSSGIAQITIFNHDNRIIYCPGANGQVDTRTWQAEWEVLAAADLVILQNEIPHEANLAIARYCHERGIKVLYNPAPARET
DLDLLTFVDYVTPNEHECQDLFPELSLEEALRTYPNKLIVTLGIRGAAYCDGKAIHVIPAIKAEAVDTTGAGDTFNGAFG
LAISHGLNTAAALRFATLASHLSVQQFGAQGGMPRLEEMKEHEAYEKAWDFK

Sequences:

>Translated_292_residues
MDLVMETKRIAKEGETVFGEAFSMVPGGKGANQAVAVGRLSLDSDRITMLGAVGQDSFGPLLLDNLKKNGVSVEYVGTVP
LSSGIAQITIFNHDNRIIYCPGANGQVDTRTWQAEWEVLAAADLVILQNEIPHEANLAIARYCHERGIKVLYNPAPARET
DLDLLTFVDYVTPNEHECQDLFPELSLEEALRTYPNKLIVTLGIRGAAYCDGKAIHVIPAIKAEAVDTTGAGDTFNGAFG
LAISHGLNTAAALRFATLASHLSVQQFGAQGGMPRLEEMKEHEAYEKAWDFK
>Mature_292_residues
MDLVMETKRIAKEGETVFGEAFSMVPGGKGANQAVAVGRLSLDSDRITMLGAVGQDSFGPLLLDNLKKNGVSVEYVGTVP
LSSGIAQITIFNHDNRIIYCPGANGQVDTRTWQAEWEVLAAADLVILQNEIPHEANLAIARYCHERGIKVLYNPAPARET
DLDLLTFVDYVTPNEHECQDLFPELSLEEALRTYPNKLIVTLGIRGAAYCDGKAIHVIPAIKAEAVDTTGAGDTFNGAFG
LAISHGLNTAAALRFATLASHLSVQQFGAQGGMPRLEEMKEHEAYEKAWDFK

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=296, Percent_Identity=34.1216216216216, Blast_Score=126, Evalue=3e-29,
Organism=Escherichia coli, GI1790193, Length=294, Percent_Identity=34.0136054421769, Blast_Score=121, Evalue=7e-29,
Organism=Caenorhabditis elegans, GI17532905, Length=295, Percent_Identity=31.5254237288136, Blast_Score=129, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6319884, Length=323, Percent_Identity=32.5077399380805, Blast_Score=125, Evalue=5e-30,
Organism=Drosophila melanogaster, GI20128807, Length=258, Percent_Identity=33.3333333333333, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 31658; Mature: 31658

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS00583 PFKB_KINASES_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLVMETKRIAKEGETVFGEAFSMVPGGKGANQAVAVGRLSLDSDRITMLGAVGQDSFGP
CCCHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCEEEEEEEECCCCCEEEEEECCCCCCCC
LLLDNLKKNGVSVEYVGTVPLSSGIAQITIFNHDNRIIYCPGANGQVDTRTWQAEWEVLA
HHHHHHHCCCCEEEEEECCCCCCCEEEEEEEECCCEEEEECCCCCCCCCEEEHHHHEEEE
AADLVILQNEIPHEANLAIARYCHERGIKVLYNPAPARETDLDLLTFVDYVTPNEHECQD
HHEEEEEECCCCCHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHCCCCCCCHHH
LFPELSLEEALRTYPNKLIVTLGIRGAAYCDGKAIHVIPAIKAEAVDTTGAGDTFNGAFG
HCCCCCHHHHHHHCCCEEEEEEECCCEEEECCCEEEEEECCCCCCCCCCCCCCCCCCEEE
LAISHGLNTAAALRFATLASHLSVQQFGAQGGMPRLEEMKEHEAYEKAWDFK
EEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDLVMETKRIAKEGETVFGEAFSMVPGGKGANQAVAVGRLSLDSDRITMLGAVGQDSFGP
CCCHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCEEEEEEEECCCCCEEEEEECCCCCCCC
LLLDNLKKNGVSVEYVGTVPLSSGIAQITIFNHDNRIIYCPGANGQVDTRTWQAEWEVLA
HHHHHHHCCCCEEEEEECCCCCCCEEEEEEEECCCEEEEECCCCCCCCCEEEHHHHEEEE
AADLVILQNEIPHEANLAIARYCHERGIKVLYNPAPARETDLDLLTFVDYVTPNEHECQD
HHEEEEEECCCCCHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHCCCCCCCHHH
LFPELSLEEALRTYPNKLIVTLGIRGAAYCDGKAIHVIPAIKAEAVDTTGAGDTFNGAFG
HCCCCCHHHHHHHCCCEEEEEEECCCEEEECCCEEEEEECCCCCCCCCCCCCCCCCCEEE
LAISHGLNTAAALRFATLASHLSVQQFGAQGGMPRLEEMKEHEAYEKAWDFK
EEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]