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The map label for this gene is ykrA [H]

Identifier: 195977528

GI number: 195977528

Start: 411645

End: 413033

Strand: Direct

Name: ykrA [H]

Synonym: Sez_0383

Alternate gene names: 195977528

Gene position: 411645-413033 (Clockwise)

Preceding gene: 195977526

Following gene: 195977530

Centisome position: 20.34

GC content: 43.84

Gene sequence:

>1389_bases
TTGACAATAAAAGCAGTCTTTTTCGACATTGATGGTACCCTGCTTAATGATCGAAAAAATGTTCAAAAAACGACGCAAAA
GGCTATTCAGCAATTAAAAAAACAAGGTATTATGGTTGGGCTGGCAACTGGTCGTGGACCTGCTTTTGTGCAGCCCTTTT
TAGAAAATTTTGGCTTGGATTTTGCAGTGACCTATAATGGGCAATACATTTTATCGCGTGATAAGGTCTTGTATCAGAAC
CAACTGCCAAAGTCAACCATTTATAAAATCATTCGCTATGCTAGCGACAAAAAGCGTGAGATTTCCCTAGGAACAGCTTC
AGGTCTTGCTGGGTCTCGGATTATTGATATGGGGACCAGTCCATTTGGCCAAATGATCAGCAGTATTGTGCCAAGAAGTC
TGGTTAAGACGGTTGAGGGCAGCTTTAAAAATCTCATCAGGCGCTTTAAGCCGCAAAGCTTCAGCAATCTTGTTACCATT
ATGAGAGAGCCCATTTATCAGATTGTCTTGGTTGCTTCTGTTGATGATACCCAAAAAATCAAGGAAAAATTTCCGCATAT
CAAGGTTACCAGAAGCAGCCCTTATTCCTTAGACTTGATTTCTAGTGGGCAGTCTAAAATCAAGGGCATTGAACGCTTGG
GCGAGATGTTTGGCTTTGAGCTCTCAGAGGTCATGGCCTTTGGAGACTCTGACAATGACTTAGAAATGCTCTCAGGCGTT
GGTGTCGGTGTTGCGATGGGAAATGCCGAGGCAGTGGTTAAAAGCGGCGCTCACTTTACAACAGCTTCAAATAACAATGA
TGGTATCTCTAAGGCGCTAGCGCATTACGGCTTGATTCATTTTGATGTGGAAAAAAGCTTTAAAAGTCGCGATGACAATT
TCAATAAGGTCAAGGATTTCCACCGTCTAATGGACGGAGACACGATTGAAACACCAAGAGGCTATTCCTTAAAGGAGGCT
GGCTATCGAGCGGATTTCAAGGTTGAGGAGCTTGTGGAATTTCTTTATGCAGCCAGTCAAGGGGATAAGCATCGCTTTTC
TCAGGCTTTGATAGACCTCCATGCTGCCCTTGATAAGGCAGCTAAGAAGGTGCAGGCCAAGGAGCACCCAGAGTCACCCC
TGGTTGGGCAGGTTGATGCTTTGACAGATCTGCTTTATTTTACCTATGGCTCATTTGTATTGATGGGAGTGGACCCTCAG
CCCATTTTTGAGACCGTCCATGAAGCCAATATGGGGAAAATTTTCCCTGATGGGAAAGCGCATTTTGATCCCATAACGCA
TAAAATTCAAAAGCCAGATGACTGGCAGGAGCTCTATGCACCAGAATCAGCCATCAAAAAAGAGTTGGACAAGCAGCTTC
AAAAATCATTGCAGCGCTTGGAAAAATAG

Upstream 100 bases:

>100_bases
CCGGTATGTAAGACGAGGATTTCTTTCATTTGATACTCATACTTCTTTCGATTTGTGATATAATTTATTTTATCACAAAT
AGAAGAGAGAACAGAAGGAT

Downstream 100 bases:

>100_bases
GATTGTCTTTATTTTAGAAAGCGCTAAAAAGCACCTTGAGCTGTGAGTTGATCTCCTAGCTGTTAGCATTTGGCCTAACG
CTTGGGGTCACTTCACTTAT

Product: hydrolase (HAD superfamily)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 462; Mature: 461

Protein sequence:

>462_residues
MTIKAVFFDIDGTLLNDRKNVQKTTQKAIQQLKKQGIMVGLATGRGPAFVQPFLENFGLDFAVTYNGQYILSRDKVLYQN
QLPKSTIYKIIRYASDKKREISLGTASGLAGSRIIDMGTSPFGQMISSIVPRSLVKTVEGSFKNLIRRFKPQSFSNLVTI
MREPIYQIVLVASVDDTQKIKEKFPHIKVTRSSPYSLDLISSGQSKIKGIERLGEMFGFELSEVMAFGDSDNDLEMLSGV
GVGVAMGNAEAVVKSGAHFTTASNNNDGISKALAHYGLIHFDVEKSFKSRDDNFNKVKDFHRLMDGDTIETPRGYSLKEA
GYRADFKVEELVEFLYAASQGDKHRFSQALIDLHAALDKAAKKVQAKEHPESPLVGQVDALTDLLYFTYGSFVLMGVDPQ
PIFETVHEANMGKIFPDGKAHFDPITHKIQKPDDWQELYAPESAIKKELDKQLQKSLQRLEK

Sequences:

>Translated_462_residues
MTIKAVFFDIDGTLLNDRKNVQKTTQKAIQQLKKQGIMVGLATGRGPAFVQPFLENFGLDFAVTYNGQYILSRDKVLYQN
QLPKSTIYKIIRYASDKKREISLGTASGLAGSRIIDMGTSPFGQMISSIVPRSLVKTVEGSFKNLIRRFKPQSFSNLVTI
MREPIYQIVLVASVDDTQKIKEKFPHIKVTRSSPYSLDLISSGQSKIKGIERLGEMFGFELSEVMAFGDSDNDLEMLSGV
GVGVAMGNAEAVVKSGAHFTTASNNNDGISKALAHYGLIHFDVEKSFKSRDDNFNKVKDFHRLMDGDTIETPRGYSLKEA
GYRADFKVEELVEFLYAASQGDKHRFSQALIDLHAALDKAAKKVQAKEHPESPLVGQVDALTDLLYFTYGSFVLMGVDPQ
PIFETVHEANMGKIFPDGKAHFDPITHKIQKPDDWQELYAPESAIKKELDKQLQKSLQRLEK
>Mature_461_residues
TIKAVFFDIDGTLLNDRKNVQKTTQKAIQQLKKQGIMVGLATGRGPAFVQPFLENFGLDFAVTYNGQYILSRDKVLYQNQ
LPKSTIYKIIRYASDKKREISLGTASGLAGSRIIDMGTSPFGQMISSIVPRSLVKTVEGSFKNLIRRFKPQSFSNLVTIM
REPIYQIVLVASVDDTQKIKEKFPHIKVTRSSPYSLDLISSGQSKIKGIERLGEMFGFELSEVMAFGDSDNDLEMLSGVG
VGVAMGNAEAVVKSGAHFTTASNNNDGISKALAHYGLIHFDVEKSFKSRDDNFNKVKDFHRLMDGDTIETPRGYSLKEAG
YRADFKVEELVEFLYAASQGDKHRFSQALIDLHAALDKAAKKVQAKEHPESPLVGQVDALTDLLYFTYGSFVLMGVDPQP
IFETVHEANMGKIFPDGKAHFDPITHKIQKPDDWQELYAPESAIKKELDKQLQKSLQRLEK

Specific function: Unknown

COG id: COG0561

COG function: function code R; Predicted hydrolases of the HAD superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. Cof family [H]

Homologues:

Organism=Escherichia coli, GI2367265, Length=293, Percent_Identity=30.0341296928328, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI87081790, Length=284, Percent_Identity=28.169014084507, Blast_Score=80, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006379
- InterPro:   IPR000150 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: NA

Molecular weight: Translated: 51580; Mature: 51448

Theoretical pI: Translated: 9.13; Mature: 9.13

Prosite motif: PS01228 COF_1 ; PS01229 COF_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIKAVFFDIDGTLLNDRKNVQKTTQKAIQQLKKQGIMVGLATGRGPAFVQPFLENFGLD
CEEEEEEEECCCCEECCHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHCCCC
FAVTYNGQYILSRDKVLYQNQLPKSTIYKIIRYASDKKREISLGTASGLAGSRIIDMGTS
EEEEECCEEEEECCCCHHHHCCCHHHHHHHHHHHCCCCCEEECCCCCCCCCCEEEECCCC
PFGQMISSIVPRSLVKTVEGSFKNLIRRFKPQSFSNLVTIMREPIYQIVLVASVDDTQKI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHEEEEECCCHHHHH
KEKFPHIKVTRSSPYSLDLISSGQSKIKGIERLGEMFGFELSEVMAFGDSDNDLEMLSGV
HHHCCCEEEECCCCCEEEHECCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCHHHHHCC
GVGVAMGNAEAVVKSGAHFTTASNNNDGISKALAHYGLIHFDVEKSFKSRDDNFNKVKDF
CCEEEECCHHHHHHCCCEEEECCCCCCHHHHHHHHHCEEEEEHHHHHHCCCCCHHHHHHH
HRLMDGDTIETPRGYSLKEAGYRADFKVEELVEFLYAASQGDKHRFSQALIDLHAALDKA
HHHHCCCCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
AKKVQAKEHPESPLVGQVDALTDLLYFTYGSFVLMGVDPQPIFETVHEANMGKIFPDGKA
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHCCCCCCCCCCCC
HFDPITHKIQKPDDWQELYAPESAIKKELDKQLQKSLQRLEK
CCCHHHHHCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TIKAVFFDIDGTLLNDRKNVQKTTQKAIQQLKKQGIMVGLATGRGPAFVQPFLENFGLD
EEEEEEEECCCCEECCHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHCCCC
FAVTYNGQYILSRDKVLYQNQLPKSTIYKIIRYASDKKREISLGTASGLAGSRIIDMGTS
EEEEECCEEEEECCCCHHHHCCCHHHHHHHHHHHCCCCCEEECCCCCCCCCCEEEECCCC
PFGQMISSIVPRSLVKTVEGSFKNLIRRFKPQSFSNLVTIMREPIYQIVLVASVDDTQKI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHEEEEECCCHHHHH
KEKFPHIKVTRSSPYSLDLISSGQSKIKGIERLGEMFGFELSEVMAFGDSDNDLEMLSGV
HHHCCCEEEECCCCCEEEHECCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCHHHHHCC
GVGVAMGNAEAVVKSGAHFTTASNNNDGISKALAHYGLIHFDVEKSFKSRDDNFNKVKDF
CCEEEECCHHHHHHCCCEEEECCCCCCHHHHHHHHHCEEEEEHHHHHHCCCCCHHHHHHH
HRLMDGDTIETPRGYSLKEAGYRADFKVEELVEFLYAASQGDKHRFSQALIDLHAALDKA
HHHHCCCCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
AKKVQAKEHPESPLVGQVDALTDLLYFTYGSFVLMGVDPQPIFETVHEANMGKIFPDGKA
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHCCCCCCCCCCCC
HFDPITHKIQKPDDWQELYAPESAIKKELDKQLQKSLQRLEK
CCCHHHHHCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]