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The map label for this gene is rfaC [H]

Identifier: 194737435

GI number: 194737435

Start: 3782652

End: 3783605

Strand: Direct

Name: rfaC [H]

Synonym: SeSA_A3911

Alternate gene names: 194737435

Gene position: 3782652-3783605 (Clockwise)

Preceding gene: 194737811

Following gene: 194737936

Centisome position: 80.33

GC content: 54.51

Gene sequence:

>954_bases
ATGCGGGTTTTGATCGTTAAAACATCATCAATGGGCGACGTATTACATACCCTGCCTGCGCTTACCGACGCGCAACAGGC
GATTCCGGGGATTCAATTTGATTGGGTTGTCGAAGAAGGGTTTGCGCAAATTCCGTCCTGGCACAGTGCTGTCGATCGCG
TGATTCCCGTCGCTATTCGCCGTTGGCGCAAAGCCTGGTTTTCCGCGCCCATTAAAGCGGAACGCACAGCCTTTCATCGG
GCGGTATGCGCATACCAATACGACGCTGTGATTGATGCGCAGGGGCTGGTGAAAAGCGCGGCGCTGGTGACGCGTCTGGC
GCATGGGATAAAGCACGGTATGGACTGGAGTACCGCCCGCGAACCGCTGGCCAGCCTGTTTTATAACCGTAAACACCATA
TCGCAAAGCAACAACATGCGGTTGAACGGACGCGCGAACTGTTCGCCAAAAGTCTGGGATACGATAAACCGCAGTCGCAG
GGCGATTATGCCATCGCAAAACATTTTCTGCATTGCCAGCAGGCGGTTAGCGATCCGTATGCGGTGTTTTTACATGCCAC
GACCCGCGATGATAAACACTGGCCGGAAGCAAACTGGCGCGAGCTTATCGGCCTGGTGGGCAACACCGGATTACGGATAA
AACTTCCCTGGGGCGCGCCTCATGAGGAGGCCCGGGCTAAACGACTGGCCGAAGGCTTTGACTATGTGGATGTGTTACCG
CGTATGAGCCTGGAGGAGGTCGCCAGAGTGCTGGCTGGCGCAAAATTTGTCGTATCGGTTGATACCGGCCTGAGCCATCT
CACCGCCGCGCTCGACAGACCGAATATTACGCTATATGGCCCAACGGACCCTGGGTTAATTGGAGGTTATGGGAAGAACC
AAATGGCATGCTGCTCACCAGAACAGAACCTGGCGAATTTAGATGCCACAAGCGTATTTGGAAAGATTCATTAA

Upstream 100 bases:

>100_bases
AAGGTGATACGGCGCAAGGCTATCACCAGAGCCTGATCGATATCACGCCGCAGCGGGTTCTGGAAGAGCTTCATTCGCTG
TTGTCGGAAGAGGGCGTTTA

Downstream 100 bases:

>100_bases
AGAGACTCTGTCTCATCCCAAACCTATTGTGGAGAAAAGATGCTAACCACATCATTAACGTTAAATAAAGAGAAATGGAA
GCCGATCTGGAATAAAGCGC

Product: ADP-heptose:LPS heptosyl transferase I

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MRVLIVKTSSMGDVLHTLPALTDAQQAIPGIQFDWVVEEGFAQIPSWHSAVDRVIPVAIRRWRKAWFSAPIKAERTAFHR
AVCAYQYDAVIDAQGLVKSAALVTRLAHGIKHGMDWSTAREPLASLFYNRKHHIAKQQHAVERTRELFAKSLGYDKPQSQ
GDYAIAKHFLHCQQAVSDPYAVFLHATTRDDKHWPEANWRELIGLVGNTGLRIKLPWGAPHEEARAKRLAEGFDYVDVLP
RMSLEEVARVLAGAKFVVSVDTGLSHLTAALDRPNITLYGPTDPGLIGGYGKNQMACCSPEQNLANLDATSVFGKIH

Sequences:

>Translated_317_residues
MRVLIVKTSSMGDVLHTLPALTDAQQAIPGIQFDWVVEEGFAQIPSWHSAVDRVIPVAIRRWRKAWFSAPIKAERTAFHR
AVCAYQYDAVIDAQGLVKSAALVTRLAHGIKHGMDWSTAREPLASLFYNRKHHIAKQQHAVERTRELFAKSLGYDKPQSQ
GDYAIAKHFLHCQQAVSDPYAVFLHATTRDDKHWPEANWRELIGLVGNTGLRIKLPWGAPHEEARAKRLAEGFDYVDVLP
RMSLEEVARVLAGAKFVVSVDTGLSHLTAALDRPNITLYGPTDPGLIGGYGKNQMACCSPEQNLANLDATSVFGKIH
>Mature_317_residues
MRVLIVKTSSMGDVLHTLPALTDAQQAIPGIQFDWVVEEGFAQIPSWHSAVDRVIPVAIRRWRKAWFSAPIKAERTAFHR
AVCAYQYDAVIDAQGLVKSAALVTRLAHGIKHGMDWSTAREPLASLFYNRKHHIAKQQHAVERTRELFAKSLGYDKPQSQ
GDYAIAKHFLHCQQAVSDPYAVFLHATTRDDKHWPEANWRELIGLVGNTGLRIKLPWGAPHEEARAKRLAEGFDYVDVLP
RMSLEEVARVLAGAKFVVSVDTGLSHLTAALDRPNITLYGPTDPGLIGGYGKNQMACCSPEQNLANLDATSVFGKIH

Specific function: Heptose transfer to the lipopolysaccharide core. It transfers the innnermost heptose to [4'-P](3-deoxy-D-manno- octulosonic acid)2-IVA [H]

COG id: COG0859

COG function: function code M; ADP-heptose:LPS heptosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 9 family [H]

Homologues:

Organism=Escherichia coli, GI1790051, Length=316, Percent_Identity=84.1772151898734, Blast_Score=555, Evalue=1e-159,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002201
- InterPro:   IPR011908 [H]

Pfam domain/function: PF01075 Glyco_transf_9 [H]

EC number: 2.4.1.-

Molecular weight: Translated: 35231; Mature: 35231

Theoretical pI: Translated: 8.85; Mature: 8.85

Prosite motif: PS00974 MANNITOL_DHGENASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLIVKTSSMGDVLHTLPALTDAQQAIPGIQFDWVVEEGFAQIPSWHSAVDRVIPVAIR
CEEEEEECCCHHHHHHHHHHHHHHHHHCCCCEEEHEEHHHHHHCCCHHHHHHHHHHHHHH
RWRKAWFSAPIKAERTAFHRAVCAYQYDAVIDAQGLVKSAALVTRLAHGIKHGMDWSTAR
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHH
EPLASLFYNRKHHIAKQQHAVERTRELFAKSLGYDKPQSQGDYAIAKHFLHCQQAVSDPY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCE
AVFLHATTRDDKHWPEANWRELIGLVGNTGLRIKLPWGAPHEEARAKRLAEGFDYVDVLP
EEEEEEECCCCCCCCCCCHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCHHHHHC
RMSLEEVARVLAGAKFVVSVDTGLSHLTAALDRPNITLYGPTDPGLIGGYGKNQMACCSP
CCCHHHHHHHHCCCEEEEEECCCHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCEECCC
EQNLANLDATSVFGKIH
CCHHHCCCHHHHHCCCC
>Mature Secondary Structure
MRVLIVKTSSMGDVLHTLPALTDAQQAIPGIQFDWVVEEGFAQIPSWHSAVDRVIPVAIR
CEEEEEECCCHHHHHHHHHHHHHHHHHCCCCEEEHEEHHHHHHCCCHHHHHHHHHHHHHH
RWRKAWFSAPIKAERTAFHRAVCAYQYDAVIDAQGLVKSAALVTRLAHGIKHGMDWSTAR
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHH
EPLASLFYNRKHHIAKQQHAVERTRELFAKSLGYDKPQSQGDYAIAKHFLHCQQAVSDPY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCE
AVFLHATTRDDKHWPEANWRELIGLVGNTGLRIKLPWGAPHEEARAKRLAEGFDYVDVLP
EEEEEEECCCCCCCCCCCHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCHHHHHC
RMSLEEVARVLAGAKFVVSVDTGLSHLTAALDRPNITLYGPTDPGLIGGYGKNQMACCSP
CCCHHHHHHHHCCCEEEEEECCCHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCEECCC
EQNLANLDATSVFGKIH
CCHHHCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1527014; 11677609; 1657881 [H]