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The map label for this gene is fimC [H]

Identifier: 194737175

GI number: 194737175

Start: 592377

End: 593069

Strand: Direct

Name: fimC [H]

Synonym: SeSA_A0590

Alternate gene names: 194737175

Gene position: 592377-593069 (Clockwise)

Preceding gene: 194734453

Following gene: 194735116

Centisome position: 12.58

GC content: 50.22

Gene sequence:

>693_bases
ATGCTGAATAGTATAAAATTAGGCTTTATTGTTCTTCTCACGTTATTTACTTCGCTGAACGTACAGGCGGCGGGGGGGAT
TGCATTAGGCGCCACGCGCGTTATTTATCCCTCGGCGGCGAAACAGACTTCTCTGGCAATCAGTAATAGCGATACTCAAG
AACGTTACCTCGTCAATTCATGGATCGAAAATAGCGCCGGGCAGAAAGAAAAAACGTTTATCGTTACGCCACCTTTATTC
GTCAGCGAACCCAAAAGCGAAAACACGCTGCGTATTATCTACGCCGGGCAACCGCTACCCGGGGATCGGGAGTCGTTATT
CTGGATGAACGTGAAAGCCATCCCGTCGGTCGATAAAAGTCATATTGAGGGAAAAAACGTTCTGCAACTGGCGATTCTGT
CGCGGATCAAACTGTTTGTGCGTCCGGCGAATTTGCCGCAGACGCCGGAAGACGCGCCGACCTTGCTGAAATTTTCCCGT
ATCGGCAACCATCTCAAGATAACCAACCCATCTGCTTATTACCTCACGCTGGTCAATATCAGCGTGGGCGCGAAAAAGAT
TGATAACGTGATGATCGCGCCAAAAAGCGACATGCAAATTCCCTTACCGACTGGCGCGCAGGGCAGCGTGACATTTCAGA
CCGTCAATGATTACGGCGCATTGACGTCGGCGACAACGGCCAGTCTCGGTTAA

Upstream 100 bases:

>100_bases
AATATGACGCCGGGACGAATTCATTCAGAAGTGTGGTTTACGCTGGTTTACCCATGAATTTTCTTGCCGACGTGACTCAA
TGCAAAAGGTATTTTTTACC

Downstream 100 bases:

>100_bases
GCAGATCGCGTGAAGCCACACGAGAACACGATGAAGAAGACAACCTGGTTTGCAGGGCGATTTCCCGGCTATGTATCACC
GTTAAGCGGCGTGGCGCTGT

Product: chaperone protein FimC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MLNSIKLGFIVLLTLFTSLNVQAAGGIALGATRVIYPSAAKQTSLAISNSDTQERYLVNSWIENSAGQKEKTFIVTPPLF
VSEPKSENTLRIIYAGQPLPGDRESLFWMNVKAIPSVDKSHIEGKNVLQLAILSRIKLFVRPANLPQTPEDAPTLLKFSR
IGNHLKITNPSAYYLTLVNISVGAKKIDNVMIAPKSDMQIPLPTGAQGSVTFQTVNDYGALTSATTASLG

Sequences:

>Translated_230_residues
MLNSIKLGFIVLLTLFTSLNVQAAGGIALGATRVIYPSAAKQTSLAISNSDTQERYLVNSWIENSAGQKEKTFIVTPPLF
VSEPKSENTLRIIYAGQPLPGDRESLFWMNVKAIPSVDKSHIEGKNVLQLAILSRIKLFVRPANLPQTPEDAPTLLKFSR
IGNHLKITNPSAYYLTLVNISVGAKKIDNVMIAPKSDMQIPLPTGAQGSVTFQTVNDYGALTSATTASLG
>Mature_230_residues
MLNSIKLGFIVLLTLFTSLNVQAAGGIALGATRVIYPSAAKQTSLAISNSDTQERYLVNSWIENSAGQKEKTFIVTPPLF
VSEPKSENTLRIIYAGQPLPGDRESLFWMNVKAIPSVDKSHIEGKNVLQLAILSRIKLFVRPANLPQTPEDAPTLLKFSR
IGNHLKITNPSAYYLTLVNISVGAKKIDNVMIAPKSDMQIPLPTGAQGSVTFQTVNDYGALTSATTASLG

Specific function: Required for the biogenesis of type 1 fimbriae. Binds and interact with fimH [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Ig-like (immunoglobulin-like) domain [H]

Homologues:

Organism=Escherichia coli, GI1786743, Length=229, Percent_Identity=62.882096069869, Blast_Score=305, Evalue=2e-84,
Organism=Escherichia coli, GI1790771, Length=231, Percent_Identity=48.0519480519481, Blast_Score=219, Evalue=1e-58,
Organism=Escherichia coli, GI1787171, Length=199, Percent_Identity=43.7185929648241, Blast_Score=168, Evalue=2e-43,
Organism=Escherichia coli, GI1789532, Length=228, Percent_Identity=39.4736842105263, Blast_Score=159, Evalue=1e-40,
Organism=Escherichia coli, GI1786936, Length=228, Percent_Identity=36.8421052631579, Blast_Score=120, Evalue=9e-29,
Organism=Escherichia coli, GI1786333, Length=233, Percent_Identity=33.4763948497854, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI87081806, Length=237, Percent_Identity=31.6455696202532, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1788428, Length=231, Percent_Identity=30.3030303030303, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1788677, Length=235, Percent_Identity=32.7659574468085, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI87082203, Length=227, Percent_Identity=30.3964757709251, Blast_Score=85, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008962
- InterPro:   IPR001829
- InterPro:   IPR016148
- InterPro:   IPR018046
- InterPro:   IPR016147 [H]

Pfam domain/function: PF02753 Pili_assembly_C; PF00345 Pili_assembly_N [H]

EC number: NA

Molecular weight: Translated: 24856; Mature: 24856

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: PS00635 PILI_CHAPERONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNSIKLGFIVLLTLFTSLNVQAAGGIALGATRVIYPSAAKQTSLAISNSDTQERYLVNS
CCCCHHHHHHHHHHHHHHCCEEECCCEEECCEEEEECCCCCCEEEEECCCCCHHHHHHHH
WIENSAGQKEKTFIVTPPLFVSEPKSENTLRIIYAGQPLPGDRESLFWMNVKAIPSVDKS
HHHCCCCCCCCEEEECCCCEEECCCCCCEEEEEECCCCCCCCCCEEEEEEEEECCCCCHH
HIEGKNVLQLAILSRIKLFVRPANLPQTPEDAPTLLKFSRIGNHLKITNPSAYYLTLVNI
HCCCCHHHHHHHHHHHHEEEECCCCCCCCCCCHHHHHHHHCCCEEEEECCCEEEEEEEEE
SVGAKKIDNVMIAPKSDMQIPLPTGAQGSVTFQTVNDYGALTSATTASLG
ECCCHHHCCEEEECCCCCEEECCCCCCCCEEEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MLNSIKLGFIVLLTLFTSLNVQAAGGIALGATRVIYPSAAKQTSLAISNSDTQERYLVNS
CCCCHHHHHHHHHHHHHHCCEEECCCEEECCEEEEECCCCCCEEEEECCCCCHHHHHHHH
WIENSAGQKEKTFIVTPPLFVSEPKSENTLRIIYAGQPLPGDRESLFWMNVKAIPSVDKS
HHHCCCCCCCCEEEECCCCEEECCCCCCEEEEEECCCCCCCCCCEEEEEEEEECCCCCHH
HIEGKNVLQLAILSRIKLFVRPANLPQTPEDAPTLLKFSRIGNHLKITNPSAYYLTLVNI
HCCCCHHHHHHHHHHHHEEEECCCCCCCCCCCHHHHHHHHCCCEEEEECCCEEEEEEEEE
SVGAKKIDNVMIAPKSDMQIPLPTGAQGSVTFQTVNDYGALTSATTASLG
ECCCHHHCCEEEECCCCCEEECCCCCCCCEEEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677609 [H]