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The map label for this gene is wzzB [H]

Identifier: 194735784

GI number: 194735784

Start: 2176110

End: 2177093

Strand: Reverse

Name: wzzB [H]

Synonym: SeSA_A2307

Alternate gene names: 194735784

Gene position: 2177093-2176110 (Counterclockwise)

Preceding gene: 194735251

Following gene: 194736501

Centisome position: 46.23

GC content: 51.12

Gene sequence:

>984_bases
ATGACAGTGGATAGTAATACGTCTTCCGGGCGTGGGAACGATCCGGAACAGATTGATTTGATTGAGTTATTGCTACAGTT
ATGGCGTGGGAAGATGACCATTATTGTAGCCGTTGTTATCGCCATTTTGCTGGCCGTAGGCTACCTGATGATAGCCAAAG
AAAAATGGACATCCACGGCGATTATTACCCAACCTGATGCCGCGCAGGTTGCCACCTATACCAACGCGCTCAACGTCTTG
TATGGCGGGAATGCTCCCAAAATCTCTGAAGTGCAGGCGAATTTTATAAGCCGCTTTAGCTCTGCGTTTTCCGCATTATC
GGAAGCGCTGGATAATCAGAAAGAGCGGGAAAAGCTCACCATTGAACAGTCGGTAAAGGGGCAAGCGCTGCCACTCTCGG
TTTCTTATGTGAGTACTACCGCTGAAGGGGCGCAGCGTCGGCTGGCGGAATATATCCAACAGGTGGATGAAGAGGTCGCT
AAGGAACTGGAAGTTGACCTGAAAGATAACATCACGCTGCAAACCAAAACGTTGCAGGAGTCTCTTGAGACGCAGGAAGT
TGTGGCGCAGGAACAAAAAGATCTGCGTATTAAGCAAATCGAAGAAGCGTTGCGCTATGCGGATGAGGCCAAAATCACGC
AGCCGCAGATTCAGCAAACCCAGGATGTTACCCAGGACACGATGTTCCTGCTGGGCAGCGATGCGCTGAAATCGATGATA
CAGAACGAAGCGACGCGTCCACTGGTCTTTTCTCCGGCCTATTACCAGACGAAGCAGACACTGCTGGACATTAAAAATCT
GAAAGTGACTGCCGATACGGTGCACGTCTATCGTTATGTGATGAAGCCGACGCTGCCGGTCCGTCGCGATAGCCCGAAAA
CAGCCATTACCCTCGTGCTGGCTGTGTTGCTGGGTGGGATGATCGGCGCCGGGATTGTGCTAGGGCGCAATGCGCTACGT
AGCTATAAGCCAAAAGCCTTGTAA

Upstream 100 bases:

>100_bases
AATGGAAATAATGTCTGATTTTTATCATTAATCCTATGGCATATATTTGCTTTATGACTACACTGTCTCCAGCTTCATCC
TTTTTTTAGTTAGGGTATCT

Downstream 100 bases:

>100_bases
GCTTCTTTGCCGGATGGTGGGTTGGCTTCGAAAGGTAAAATTTCTCACTAAAAAACCGGGCATTGCCCGGTTTTTTTATG
CTTATTGATGACGCTTACGA

Product: chain length determinant protein

Products: NA

Alternate protein names: Polysaccharide antigen chain regulator [H]

Number of amino acids: Translated: 327; Mature: 326

Protein sequence:

>327_residues
MTVDSNTSSGRGNDPEQIDLIELLLQLWRGKMTIIVAVVIAILLAVGYLMIAKEKWTSTAIITQPDAAQVATYTNALNVL
YGGNAPKISEVQANFISRFSSAFSALSEALDNQKEREKLTIEQSVKGQALPLSVSYVSTTAEGAQRRLAEYIQQVDEEVA
KELEVDLKDNITLQTKTLQESLETQEVVAQEQKDLRIKQIEEALRYADEAKITQPQIQQTQDVTQDTMFLLGSDALKSMI
QNEATRPLVFSPAYYQTKQTLLDIKNLKVTADTVHVYRYVMKPTLPVRRDSPKTAITLVLAVLLGGMIGAGIVLGRNALR
SYKPKAL

Sequences:

>Translated_327_residues
MTVDSNTSSGRGNDPEQIDLIELLLQLWRGKMTIIVAVVIAILLAVGYLMIAKEKWTSTAIITQPDAAQVATYTNALNVL
YGGNAPKISEVQANFISRFSSAFSALSEALDNQKEREKLTIEQSVKGQALPLSVSYVSTTAEGAQRRLAEYIQQVDEEVA
KELEVDLKDNITLQTKTLQESLETQEVVAQEQKDLRIKQIEEALRYADEAKITQPQIQQTQDVTQDTMFLLGSDALKSMI
QNEATRPLVFSPAYYQTKQTLLDIKNLKVTADTVHVYRYVMKPTLPVRRDSPKTAITLVLAVLLGGMIGAGIVLGRNALR
SYKPKAL
>Mature_326_residues
TVDSNTSSGRGNDPEQIDLIELLLQLWRGKMTIIVAVVIAILLAVGYLMIAKEKWTSTAIITQPDAAQVATYTNALNVLY
GGNAPKISEVQANFISRFSSAFSALSEALDNQKEREKLTIEQSVKGQALPLSVSYVSTTAEGAQRRLAEYIQQVDEEVAK
ELEVDLKDNITLQTKTLQESLETQEVVAQEQKDLRIKQIEEALRYADEAKITQPQIQQTQDVTQDTMFLLGSDALKSMIQ
NEATRPLVFSPAYYQTKQTLLDIKNLKVTADTVHVYRYVMKPTLPVRRDSPKTAITLVLAVLLGGMIGAGIVLGRNALRS
YKPKAL

Specific function: Confers a modal distribution of chain length on the O- antigen component of lipopolysaccharide (LPS). Gives rise to a reduced number of short chain molecules and increases in numbers of longer molecules, with a modal value of 20 [H]

COG id: COG3765

COG function: function code M; Chain length determinant protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the wzzB/cld/rol family [H]

Homologues:

Organism=Escherichia coli, GI87082029, Length=326, Percent_Identity=71.7791411042945, Blast_Score=475, Evalue=1e-135,
Organism=Escherichia coli, GI87082332, Length=333, Percent_Identity=27.3273273273273, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1786802, Length=348, Percent_Identity=28.1609195402299, Blast_Score=100, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003856 [H]

Pfam domain/function: PF02706 Wzz [H]

EC number: NA

Molecular weight: Translated: 36217; Mature: 36086

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVDSNTSSGRGNDPEQIDLIELLLQLWRGKMTIIVAVVIAILLAVGYLMIAKEKWTSTA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
IITQPDAAQVATYTNALNVLYGGNAPKISEVQANFISRFSSAFSALSEALDNQKEREKLT
EEECCCHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
IEQSVKGQALPLSVSYVSTTAEGAQRRLAEYIQQVDEEVAKELEVDLKDNITLQTKTLQE
HHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHH
SLETQEVVAQEQKDLRIKQIEEALRYADEAKITQPQIQQTQDVTQDTMFLLGSDALKSMI
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHH
QNEATRPLVFSPAYYQTKQTLLDIKNLKVTADTVHVYRYVMKPTLPVRRDSPKTAITLVL
HCCCCCCEEECCHHHHHHHHHHHHHCCEEEHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
AVLLGGMIGAGIVLGRNALRSYKPKAL
HHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TVDSNTSSGRGNDPEQIDLIELLLQLWRGKMTIIVAVVIAILLAVGYLMIAKEKWTSTA
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
IITQPDAAQVATYTNALNVLYGGNAPKISEVQANFISRFSSAFSALSEALDNQKEREKLT
EEECCCHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
IEQSVKGQALPLSVSYVSTTAEGAQRRLAEYIQQVDEEVAKELEVDLKDNITLQTKTLQE
HHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHH
SLETQEVVAQEQKDLRIKQIEEALRYADEAKITQPQIQQTQDVTQDTMFLLGSDALKSMI
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHH
QNEATRPLVFSPAYYQTKQTLLDIKNLKVTADTVHVYRYVMKPTLPVRRDSPKTAITLVL
HCCCCCCEEECCHHHHHHHHHHHHHCCEEEHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
AVLLGGMIGAGIVLGRNALRSYKPKAL
HHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7682279; 1379582; 11677609 [H]