Click here to switch to the map view.

The map label for this gene is fimH [H]

Identifier: 194735351

GI number: 194735351

Start: 28429

End: 29436

Strand: Direct

Name: fimH [H]

Synonym: SeSA_A0026

Alternate gene names: 194735351

Gene position: 28429-29436 (Clockwise)

Preceding gene: 194733954

Following gene: 194737224

Centisome position: 0.6

GC content: 50.4

Gene sequence:

>1008_bases
ATGAAAATACCTCTTTTATTTGCTCTGCTGGTGGGAAGTGTCGTATCGCAGTACGCATTCGCAGACGTGTGTAAAAACGT
TAACGGTGTACCTTCCAGTATTAATTACGATTTAACGACCACTCTGACGGCAGAACAAAACCAGGTGGGAAAGACGGTTC
AACTGGAAAAAAGCCAGGAAGTTAATGTACAGGCGGTGTGTCCCGCCGGCGCGGCGACCAATAGCCAGACTTATCGCTCC
TATGTGTCGCCATATCCGGTCGTAGAAACGAGCGGTAACTGGAAATATTTAAAGCTGGACCCGGACTATCTTGAAGGCGG
AATGCGAATTGAGGATTCTTCGGCGGGCGATATCTATCCGCCAATGAACAATGTCCTGATGGGATATGATGAAAATGTGA
AAGCGGGTCAACCGTTTTACGTTCGTGACTCAAATCTGGAGTTTCAGCTCAAAATTGTTAAACCGTTCGTCGGCACGGTG
AATATTAGTCCTAAGACTATGTTCAATGTTTATGTCATGACCGCCGCAGGCGATCCGCTGACAGATGTCGTGTACAGCAT
TCTTTATAGTGGAACGGTGACCGTACCGCAAAGCTGCGAAATCAACGCCGGACAAACGATTCTGGTGAATTTCGGCGCAT
TGTACAGTGGCAATTTCAACCATGCAGGCCAAAAGCCGGAGGGGGTACGAGCGAAAAAATTTAGCGTACCGGTAAAGTGC
AGCGGCCTGGATTCGCAGGTCAATTTAACGATGCGTCTTATCGCTACGCCGGATAGCCACGTTCCCCAGGCTATCGCTTC
GGATAATGCGGATGTCGGCGTAGTGGTCGAAACCGATGAAGGAAACGCGCTTATCCCCAATGATGCACAGAGCGTCGCGC
CTTTTATCACCGATAGCGCCGGACGCGCTAACATCACATTGCAAGCCTACCCGGTGAGTACAACAGGCGAAACGCCAGCG
GAAGGGGCGTTTACCGCGCTGGCCAGCCTGCGAGTGGACTTTGACTAA

Upstream 100 bases:

>100_bases
CGTTCGCTGGGGGAACCTGCCGGATCAACAGTGTGTCGCGTCCTATCATCTCTCTTCCTCCCGTCAGATTCTGAGTCGAC
AACATGCGGAGTGTCATTAA

Downstream 100 bases:

>100_bases
ATGAACAGATCACACTGCGCTCTTTTTGCCATGGGACTGATGCTGTGTCCACAAATCAATGCCAGCGCTGACGACCTCGC
TTATAACCTCGAATTTACCG

Product: mannose binding protein FimH

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MKIPLLFALLVGSVVSQYAFADVCKNVNGVPSSINYDLTTTLTAEQNQVGKTVQLEKSQEVNVQAVCPAGAATNSQTYRS
YVSPYPVVETSGNWKYLKLDPDYLEGGMRIEDSSAGDIYPPMNNVLMGYDENVKAGQPFYVRDSNLEFQLKIVKPFVGTV
NISPKTMFNVYVMTAAGDPLTDVVYSILYSGTVTVPQSCEINAGQTILVNFGALYSGNFNHAGQKPEGVRAKKFSVPVKC
SGLDSQVNLTMRLIATPDSHVPQAIASDNADVGVVVETDEGNALIPNDAQSVAPFITDSAGRANITLQAYPVSTTGETPA
EGAFTALASLRVDFD

Sequences:

>Translated_335_residues
MKIPLLFALLVGSVVSQYAFADVCKNVNGVPSSINYDLTTTLTAEQNQVGKTVQLEKSQEVNVQAVCPAGAATNSQTYRS
YVSPYPVVETSGNWKYLKLDPDYLEGGMRIEDSSAGDIYPPMNNVLMGYDENVKAGQPFYVRDSNLEFQLKIVKPFVGTV
NISPKTMFNVYVMTAAGDPLTDVVYSILYSGTVTVPQSCEINAGQTILVNFGALYSGNFNHAGQKPEGVRAKKFSVPVKC
SGLDSQVNLTMRLIATPDSHVPQAIASDNADVGVVVETDEGNALIPNDAQSVAPFITDSAGRANITLQAYPVSTTGETPA
EGAFTALASLRVDFD
>Mature_335_residues
MKIPLLFALLVGSVVSQYAFADVCKNVNGVPSSINYDLTTTLTAEQNQVGKTVQLEKSQEVNVQAVCPAGAATNSQTYRS
YVSPYPVVETSGNWKYLKLDPDYLEGGMRIEDSSAGDIYPPMNNVLMGYDENVKAGQPFYVRDSNLEFQLKIVKPFVGTV
NISPKTMFNVYVMTAAGDPLTDVVYSILYSGTVTVPQSCEINAGQTILVNFGALYSGNFNHAGQKPEGVRAKKFSVPVKC
SGLDSQVNLTMRLIATPDSHVPQAIASDNADVGVVVETDEGNALIPNDAQSVAPFITDSAGRANITLQAYPVSTTGETPA
EGAFTALASLRVDFD

Specific function: Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Seems to be a mannose-binding adhesin [H]

COG id: COG3539

COG function: function code NU; P pilus assembly protein, pilin FimA

Gene ontology:

Cell location: Fimbrium [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI145693100, Length=323, Percent_Identity=44.2724458204334, Blast_Score=255, Evalue=3e-69,
Organism=Escherichia coli, GI1787173, Length=363, Percent_Identity=31.404958677686, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1789534, Length=206, Percent_Identity=31.5533980582524, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008966 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 35864; Mature: 35864

Theoretical pI: Translated: 4.36; Mature: 4.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIPLLFALLVGSVVSQYAFADVCKNVNGVPSSINYDLTTTLTAEQNQVGKTVQLEKSQE
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCEEEECCCCC
VNVQAVCPAGAATNSQTYRSYVSPYPVVETSGNWKYLKLDPDYLEGGMRIEDSSAGDIYP
CCEEEECCCCCCCCCHHHHHHCCCCCEEEECCCEEEEEECHHHHCCCCEEECCCCCCCCC
PMNNVLMGYDENVKAGQPFYVRDSNLEFQLKIVKPFVGTVNISPKTMFNVYVMTAAGDPL
CCCCEEECCCCCCCCCCCEEEECCCCEEEEEEECCCEEEEECCCCEEEEEEEEEECCCCH
TDVVYSILYSGTVTVPQSCEINAGQTILVNFGALYSGNFNHAGQKPEGVRAKKFSVPVKC
HHHHHHHHHCCEEECCCCCCCCCCCEEEEEECEEECCCCCCCCCCCCCCCEEEEECCEEE
SGLDSQVNLTMRLIATPDSHVPQAIASDNADVGVVVETDEGNALIPNDAQSVAPFITDSA
CCCCCCEEEEEEEEECCCCCCCHHHHCCCCCEEEEEEECCCCEECCCCHHHHCCEEECCC
GRANITLQAYPVSTTGETPAEGAFTALASLRVDFD
CCEEEEEEEEECCCCCCCCCCHHHEEEEEEEEECC
>Mature Secondary Structure
MKIPLLFALLVGSVVSQYAFADVCKNVNGVPSSINYDLTTTLTAEQNQVGKTVQLEKSQE
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCEEEECCCCC
VNVQAVCPAGAATNSQTYRSYVSPYPVVETSGNWKYLKLDPDYLEGGMRIEDSSAGDIYP
CCEEEECCCCCCCCCHHHHHHCCCCCEEEECCCEEEEEECHHHHCCCCEEECCCCCCCCC
PMNNVLMGYDENVKAGQPFYVRDSNLEFQLKIVKPFVGTVNISPKTMFNVYVMTAAGDPL
CCCCEEECCCCCCCCCCCEEEECCCCEEEEEEECCCEEEEECCCCEEEEEEEEEECCCCH
TDVVYSILYSGTVTVPQSCEINAGQTILVNFGALYSGNFNHAGQKPEGVRAKKFSVPVKC
HHHHHHHHHCCEEECCCCCCCCCCCEEEEEECEEECCCCCCCCCCCCCCCEEEEECCEEE
SGLDSQVNLTMRLIATPDSHVPQAIASDNADVGVVVETDEGNALIPNDAQSVAPFITDSA
CCCCCCEEEEEEEEECCCCCCCHHHHCCCCCEEEEEEECCCCEECCCCHHHHCCEEECCC
GRANITLQAYPVSTTGETPAEGAFTALASLRVDFD
CCEEEEEEEEECCCCCCCCCCHHHEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677609 [H]