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The map label for this gene is dsdX [H]

Identifier: 194735344

GI number: 194735344

Start: 3884889

End: 3886226

Strand: Direct

Name: dsdX [H]

Synonym: SeSA_A4010

Alternate gene names: 194735344

Gene position: 3884889-3886226 (Clockwise)

Preceding gene: 194736656

Following gene: 194736441

Centisome position: 82.5

GC content: 56.13

Gene sequence:

>1338_bases
ATGCACGCTCAAATCTGGGTAGTGAGCACGCTGCTGATCAGCATCGTGTTAATCGTATTGACCATCGTGAAGTTTAAATT
CCACCCCTTCCTGGCGTTACTGCTCGCCAGTTTCTTTGTCGGCGCGATGATGGGCATGGGGCCGCTGGAGATGGTCACGG
CGATAGAAAACGGAATAGGCGGTACGCTCGGTTTTCTGGCCGCCGTTATCGGTCTTGGCACCATCCTCGGCAAAATGATG
GAGGTTTCCGGCGCGGCGGAACGCATCGGGCTTACGCTCCAGCGCTGTCGCTGGCTCTCTGCTGACGTGATCATGGTACT
GGTGGGACTGATTTGCGGTATCACGTTGTTCGTGGAAGTGGGCGTCGTGTTGCTCATCCCACTGGCGTTTTCTATCGCTA
AAAAAACCCATACCTCGCTGCTGAAGCTGGCCATTCCGCTGTGTACCGCGCTGATGGCCGTCCATTGCGTGGTACCGCCG
CATCCGGCTGCGCTGTTTGTCGCAAATAAACTGGGGGCGGATATCGGCTCGGTGATTGTCTACGGTCTGCTGGTCGGACT
GATGGCCTCATTGGTCGGCGGCCCGCTGTTCTTAAAGTTTCTGGGTAATCGTCTGCCGTTCAAGCCCGTACCGACAGAGT
TTGCGGATCTTGAAGTGCGCGCCGAAAACACCCTGCCATCGCTGGGCGCAACGCTATTTACCGTTCTGTTGCCGATTGGC
CTGATGCTGGTGAAAACCGTCGCTGAACTGAATATGGCGAAAGACGGCACGTTGTATACGCTGCTGGAGTTTATCGGTAA
TCCGATCACCGCGATGTTTATCGCTGTCTTTGTAGCGTATTACATACTCGGTCTGCGCCAGCATATGGGGATGAGCGCGC
TACTTACCCACACCGAAAACGGCTTTGGCGCCATTGCGAACATCCTGCTGATTATCGGCGCGGGCGGCGCGTTCAACGCC
ATTCTCAAAAGTAGCGGGCTGGCGGACACGCTGGCGGTGATCCTCTCAAATATGCATATGCACCCGATTCTGCTGGCATG
GCTGGTAGCGCTGATTCTGCACGCGGCGGTCGGCTCTGCGACGGTGGCGATGATGGGCGCCACGGCGATTGTTGCGCCCA
TGCTGCCGCTCTATCCTGACGTCAGCCCGGAGATCATTGCGATTGCCATTGGTTCCGGCGCCATTGGCTGCACGATCGTG
ACCGATTCCCTGTTCTGGCTGGTCAAGCAGTATTGCGGCGCTACGCTGAATGAAACGTTTAAATACTATACGACGGCCAC
GTTTATCGCATCTGTCGTTGCACTGGCTGGCACATTCCTGCTTTCCTTTATCATCTGA

Upstream 100 bases:

>100_bases
TGATTCAATTTACATCATGTGAATGGCAAATTATATCGTTTGTCAGGAGGTGCTGTTTTTCTGTCCAATAAGAACAGATT
AATCACAGGGTAGGTGAGAT

Downstream 100 bases:

>100_bases
TCGTAAAGAGACGTACTATGGAAAACATACAAAAGCTCATCGCCCGGTATCCTTTGGTCGAGGATCTGGTCGCCCTCAAA
GAAACCACCTGGTTTAACCC

Product: permease DsdX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MHAQIWVVSTLLISIVLIVLTIVKFKFHPFLALLLASFFVGAMMGMGPLEMVTAIENGIGGTLGFLAAVIGLGTILGKMM
EVSGAAERIGLTLQRCRWLSADVIMVLVGLICGITLFVEVGVVLLIPLAFSIAKKTHTSLLKLAIPLCTALMAVHCVVPP
HPAALFVANKLGADIGSVIVYGLLVGLMASLVGGPLFLKFLGNRLPFKPVPTEFADLEVRAENTLPSLGATLFTVLLPIG
LMLVKTVAELNMAKDGTLYTLLEFIGNPITAMFIAVFVAYYILGLRQHMGMSALLTHTENGFGAIANILLIIGAGGAFNA
ILKSSGLADTLAVILSNMHMHPILLAWLVALILHAAVGSATVAMMGATAIVAPMLPLYPDVSPEIIAIAIGSGAIGCTIV
TDSLFWLVKQYCGATLNETFKYYTTATFIASVVALAGTFLLSFII

Sequences:

>Translated_445_residues
MHAQIWVVSTLLISIVLIVLTIVKFKFHPFLALLLASFFVGAMMGMGPLEMVTAIENGIGGTLGFLAAVIGLGTILGKMM
EVSGAAERIGLTLQRCRWLSADVIMVLVGLICGITLFVEVGVVLLIPLAFSIAKKTHTSLLKLAIPLCTALMAVHCVVPP
HPAALFVANKLGADIGSVIVYGLLVGLMASLVGGPLFLKFLGNRLPFKPVPTEFADLEVRAENTLPSLGATLFTVLLPIG
LMLVKTVAELNMAKDGTLYTLLEFIGNPITAMFIAVFVAYYILGLRQHMGMSALLTHTENGFGAIANILLIIGAGGAFNA
ILKSSGLADTLAVILSNMHMHPILLAWLVALILHAAVGSATVAMMGATAIVAPMLPLYPDVSPEIIAIAIGSGAIGCTIV
TDSLFWLVKQYCGATLNETFKYYTTATFIASVVALAGTFLLSFII
>Mature_445_residues
MHAQIWVVSTLLISIVLIVLTIVKFKFHPFLALLLASFFVGAMMGMGPLEMVTAIENGIGGTLGFLAAVIGLGTILGKMM
EVSGAAERIGLTLQRCRWLSADVIMVLVGLICGITLFVEVGVVLLIPLAFSIAKKTHTSLLKLAIPLCTALMAVHCVVPP
HPAALFVANKLGADIGSVIVYGLLVGLMASLVGGPLFLKFLGNRLPFKPVPTEFADLEVRAENTLPSLGATLFTVLLPIG
LMLVKTVAELNMAKDGTLYTLLEFIGNPITAMFIAVFVAYYILGLRQHMGMSALLTHTENGFGAIANILLIIGAGGAFNA
ILKSSGLADTLAVILSNMHMHPILLAWLVALILHAAVGSATVAMMGATAIVAPMLPLYPDVSPEIIAIAIGSGAIGCTIV
TDSLFWLVKQYCGATLNETFKYYTTATFIASVVALAGTFLLSFII

Specific function: Probable permease for an unknown substrate [H]

COG id: COG2610

COG function: function code GE; H+/gluconate symporter and related permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gntP permease family [H]

Homologues:

Organism=Escherichia coli, GI1788707, Length=445, Percent_Identity=93.0337078651685, Blast_Score=823, Evalue=0.0,
Organism=Escherichia coli, GI48994935, Length=439, Percent_Identity=35.9908883826879, Blast_Score=261, Evalue=5e-71,
Organism=Escherichia coli, GI1790716, Length=429, Percent_Identity=34.2657342657343, Blast_Score=252, Evalue=3e-68,
Organism=Escherichia coli, GI1790776, Length=446, Percent_Identity=32.0627802690583, Blast_Score=224, Evalue=1e-59,
Organism=Escherichia coli, GI2367370, Length=427, Percent_Identity=33.9578454332553, Blast_Score=221, Evalue=7e-59,
Organism=Escherichia coli, GI48994939, Length=429, Percent_Identity=34.965034965035, Blast_Score=207, Evalue=9e-55,
Organism=Escherichia coli, GI1789097, Length=439, Percent_Identity=30.0683371298405, Blast_Score=159, Evalue=4e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003474 [H]

Pfam domain/function: PF02447 GntP_permease [H]

EC number: NA

Molecular weight: Translated: 46878; Mature: 46878

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHAQIWVVSTLLISIVLIVLTIVKFKFHPFLALLLASFFVGAMMGMGPLEMVTAIENGIG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCC
GTLGFLAAVIGLGTILGKMMEVSGAAERIGLTLQRCRWLSADVIMVLVGLICGITLFVEV
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
GVVLLIPLAFSIAKKTHTSLLKLAIPLCTALMAVHCVVPPHPAALFVANKLGADIGSVIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHH
YGLLVGLMASLVGGPLFLKFLGNRLPFKPVPTEFADLEVRAENTLPSLGATLFTVLLPIG
HHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCCHHCCEEEECCCCCHHHHHHHHHHHHHH
LMLVKTVAELNMAKDGTLYTLLEFIGNPITAMFIAVFVAYYILGLRQHMGMSALLTHTEN
HHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCC
GFGAIANILLIIGAGGAFNAILKSSGLADTLAVILSNMHMHPILLAWLVALILHAAVGSA
CHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
TVAMMGATAIVAPMLPLYPDVSPEIIAIAIGSGAIGCTIVTDSLFWLVKQYCGATLNETF
HHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCHHHHH
KYYTTATFIASVVALAGTFLLSFII
HHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MHAQIWVVSTLLISIVLIVLTIVKFKFHPFLALLLASFFVGAMMGMGPLEMVTAIENGIG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCC
GTLGFLAAVIGLGTILGKMMEVSGAAERIGLTLQRCRWLSADVIMVLVGLICGITLFVEV
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
GVVLLIPLAFSIAKKTHTSLLKLAIPLCTALMAVHCVVPPHPAALFVANKLGADIGSVIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHH
YGLLVGLMASLVGGPLFLKFLGNRLPFKPVPTEFADLEVRAENTLPSLGATLFTVLLPIG
HHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCCHHCCEEEECCCCCHHHHHHHHHHHHHH
LMLVKTVAELNMAKDGTLYTLLEFIGNPITAMFIAVFVAYYILGLRQHMGMSALLTHTEN
HHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCC
GFGAIANILLIIGAGGAFNAILKSSGLADTLAVILSNMHMHPILLAWLVALILHAAVGSA
CHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
TVAMMGATAIVAPMLPLYPDVSPEIIAIAIGSGAIGCTIVTDSLFWLVKQYCGATLNETF
HHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCHHHHH
KYYTTATFIASVVALAGTFLLSFII
HHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592420; 3275618; 9205837; 9278503; 3029015; 1659648; 12218016 [H]