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The map label for this gene is dsdA [H]

Identifier: 194736441

GI number: 194736441

Start: 3886244

End: 3887566

Strand: Direct

Name: dsdA [H]

Synonym: SeSA_A4011

Alternate gene names: 194736441

Gene position: 3886244-3887566 (Clockwise)

Preceding gene: 194735344

Following gene: 194736000

Centisome position: 82.53

GC content: 56.31

Gene sequence:

>1323_bases
ATGGAAAACATACAAAAGCTCATCGCCCGGTATCCTTTGGTCGAGGATCTGGTCGCCCTCAAAGAAACCACCTGGTTTAA
CCCGGGCGCCACCTCTCTTGCACAAGGTCTACCGTATGTCGGCCTGACGGAGCAGGACGTAAACGCCGCCCATGACCGTC
TGGCGCGCTTTGCGCCGTATCTGGCGAAAGCGTTTCCGCAAACCGCTGCCGCTGGCGGCATGATCGAATCTGACGTGGTC
GCTATTCCGGCCATGCAAAAGCGGCTGGAAAAAGAGTATGGGCAAACGATCGACGGTGAAATGCTGTTAAAAAAAGACAG
TCACCTGGCAATCTCTGGTTCCATTAAAGCGCGCGGCGGCATCTACGAGGTGCTAACGCACGCGGAAAAACTGGCGCTGG
AGGCGGGTCTGTTAACCACCGACGATGACTATAGCGTGTTGCTTTCGCCGGAATTTAAACAATTCTTCAGCCAGTACAGT
ATCGCCGTCGGTTCAACCGGCAATCTGGGGCTATCGATCGGTATCATGAGCGCCTGCATCGGTTTTAAAGTGACGGTACA
TATGTCTGCCGACGCCCGCGCCTGGAAAAAAGCGAAGCTGCGTAGCCACGGCGTGACGGTCGTGGAATACGAAGATGATT
ACGGCGTGGCGGTTGAGCAGGGTCGTAAAGCAGCGCAATCCGATCCAAACTGTTTCTTTATCGACGATGAAAACTCCCGC
ACGCTATTTCTGGGCTATGCGGTAGCGGGTCAGCGTCTGAAAGCGCAATTCGCGCAACAGGGACGCGTCGTTGACGCCAG
CCACCCACTGTTTGTTTATCTACCGTGCGGCGTTGGCGGCGGCCCTGGCGGCGTCGCCTTTGGCCTGAAACTGGCATTTG
GCGACAACGTCCACTGTTTCTTTGCCGAACCGACCCATTCACCCTGCATGTTACTCGGCGTTTATACCGGTCTGCACGAT
GCCATCTCAGTACAAGATATCGGTATTGATAACCTGACGGCGGCTGACGGCCTGGCGGTAGGTCGCGCTTCAGGCTTTGT
TGGTCGGGCAATGGAGCGTCTGCTTGACGGCCTCTATACCTTAGACGATCAAACAATGTATGACATGCTGGGCTGGCTGG
CGCAGGAGGAAGGAATTCGACTGGAGCCATCAGCTCTGGCAGGGATGGCCGGGCCACAGCGCATTTGCGCCGCCACCGTG
TATCAGCAAAGGCATGGATTCAGTCAGACGCAGCTCGGCAACGCGACGCATCTGGTATGGGCAACCGGGGGCGGCATGGT
GCCGGAGGATGAAATGGAACAATACCTGGCAAAAGGACGCTAA

Upstream 100 bases:

>100_bases
CGTTTAAATACTATACGACGGCCACGTTTATCGCATCTGTCGTTGCACTGGCTGGCACATTCCTGCTTTCCTTTATCATC
TGATCGTAAAGAGACGTACT

Downstream 100 bases:

>100_bases
TACTCGCTCAGTGCCGGAAAGACGGCAGCGCCATCCGGCACGCCATCGCCTGATGGCGCTACGCTTATCAGGCTTACGAC
GCTAACGCAGCATCGCCATC

Product: D-serine dehydratase

Products: NA

Alternate protein names: D-serine deaminase; DSD [H]

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MENIQKLIARYPLVEDLVALKETTWFNPGATSLAQGLPYVGLTEQDVNAAHDRLARFAPYLAKAFPQTAAAGGMIESDVV
AIPAMQKRLEKEYGQTIDGEMLLKKDSHLAISGSIKARGGIYEVLTHAEKLALEAGLLTTDDDYSVLLSPEFKQFFSQYS
IAVGSTGNLGLSIGIMSACIGFKVTVHMSADARAWKKAKLRSHGVTVVEYEDDYGVAVEQGRKAAQSDPNCFFIDDENSR
TLFLGYAVAGQRLKAQFAQQGRVVDASHPLFVYLPCGVGGGPGGVAFGLKLAFGDNVHCFFAEPTHSPCMLLGVYTGLHD
AISVQDIGIDNLTAADGLAVGRASGFVGRAMERLLDGLYTLDDQTMYDMLGWLAQEEGIRLEPSALAGMAGPQRICAATV
YQQRHGFSQTQLGNATHLVWATGGGMVPEDEMEQYLAKGR

Sequences:

>Translated_440_residues
MENIQKLIARYPLVEDLVALKETTWFNPGATSLAQGLPYVGLTEQDVNAAHDRLARFAPYLAKAFPQTAAAGGMIESDVV
AIPAMQKRLEKEYGQTIDGEMLLKKDSHLAISGSIKARGGIYEVLTHAEKLALEAGLLTTDDDYSVLLSPEFKQFFSQYS
IAVGSTGNLGLSIGIMSACIGFKVTVHMSADARAWKKAKLRSHGVTVVEYEDDYGVAVEQGRKAAQSDPNCFFIDDENSR
TLFLGYAVAGQRLKAQFAQQGRVVDASHPLFVYLPCGVGGGPGGVAFGLKLAFGDNVHCFFAEPTHSPCMLLGVYTGLHD
AISVQDIGIDNLTAADGLAVGRASGFVGRAMERLLDGLYTLDDQTMYDMLGWLAQEEGIRLEPSALAGMAGPQRICAATV
YQQRHGFSQTQLGNATHLVWATGGGMVPEDEMEQYLAKGR
>Mature_440_residues
MENIQKLIARYPLVEDLVALKETTWFNPGATSLAQGLPYVGLTEQDVNAAHDRLARFAPYLAKAFPQTAAAGGMIESDVV
AIPAMQKRLEKEYGQTIDGEMLLKKDSHLAISGSIKARGGIYEVLTHAEKLALEAGLLTTDDDYSVLLSPEFKQFFSQYS
IAVGSTGNLGLSIGIMSACIGFKVTVHMSADARAWKKAKLRSHGVTVVEYEDDYGVAVEQGRKAAQSDPNCFFIDDENSR
TLFLGYAVAGQRLKAQFAQQGRVVDASHPLFVYLPCGVGGGPGGVAFGLKLAFGDNVHCFFAEPTHSPCMLLGVYTGLHD
AISVQDIGIDNLTAADGLAVGRASGFVGRAMERLLDGLYTLDDQTMYDMLGWLAQEEGIRLEPSALAGMAGPQRICAATV
YQQRHGFSQTQLGNATHLVWATGGGMVPEDEMEQYLAKGR

Specific function: Unknown

COG id: COG3048

COG function: function code E; D-serine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serine/threonine dehydratase family. DsdA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788708, Length=442, Percent_Identity=88.6877828054299, Blast_Score=788, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011780
- InterPro:   IPR001926
- InterPro:   IPR000634 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.3.1.18 [H]

Molecular weight: Translated: 47384; Mature: 47384

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS00165 DEHYDRATASE_SER_THR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENIQKLIARYPLVEDLVALKETTWFNPGATSLAQGLPYVGLTEQDVNAAHDRLARFAPY
CCHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
LAKAFPQTAAAGGMIESDVVAIPAMQKRLEKEYGQTIDGEMLLKKDSHLAISGSIKARGG
HHHHCCHHHHCCCCCCCCEEECHHHHHHHHHHHCCCCCCCEEEECCCCEEEECCCCCCCC
IYEVLTHAEKLALEAGLLTTDDDYSVLLSPEFKQFFSQYSIAVGSTGNLGLSIGIMSACI
HHHHHHHHHHHHHHHCCEECCCCCEEEECHHHHHHHHHHEEEECCCCCCEEHHHHHHHHH
GFKVTVHMSADARAWKKAKLRSHGVTVVEYEDDYGVAVEQGRKAAQSDPNCFFIDDENSR
CEEEEEEECCCHHHHHHHHHHHCCEEEEEECCCCCCCHHHCCHHHCCCCCEEEEECCCCC
TLFLGYAVAGQRLKAQFAQQGRVVDASHPLFVYLPCGVGGGPGGVAFGLKLAFGDNVHCF
EEEEEEEHHHHHHHHHHHHCCCEEECCCCEEEEEECCCCCCCCCCEEEEEEEECCCEEEE
FAEPTHSPCMLLGVYTGLHDAISVQDIGIDNLTAADGLAVGRASGFVGRAMERLLDGLYT
EECCCCCCEEEEEEHHCHHHHCEEEECCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHC
LDDQTMYDMLGWLAQEEGIRLEPSALAGMAGPQRICAATVYQQRHGFSQTQLGNATHLVW
CCCHHHHHHHHHHHHCCCCEECHHHHHCCCCHHHHHHHHHHHHHCCCCHHCCCCCEEEEE
ATGGGMVPEDEMEQYLAKGR
ECCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MENIQKLIARYPLVEDLVALKETTWFNPGATSLAQGLPYVGLTEQDVNAAHDRLARFAPY
CCHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
LAKAFPQTAAAGGMIESDVVAIPAMQKRLEKEYGQTIDGEMLLKKDSHLAISGSIKARGG
HHHHCCHHHHCCCCCCCCEEECHHHHHHHHHHHCCCCCCCEEEECCCCEEEECCCCCCCC
IYEVLTHAEKLALEAGLLTTDDDYSVLLSPEFKQFFSQYSIAVGSTGNLGLSIGIMSACI
HHHHHHHHHHHHHHHCCEECCCCCEEEECHHHHHHHHHHEEEECCCCCCEEHHHHHHHHH
GFKVTVHMSADARAWKKAKLRSHGVTVVEYEDDYGVAVEQGRKAAQSDPNCFFIDDENSR
CEEEEEEECCCHHHHHHHHHHHCCEEEEEECCCCCCCHHHCCHHHCCCCCEEEEECCCCC
TLFLGYAVAGQRLKAQFAQQGRVVDASHPLFVYLPCGVGGGPGGVAFGLKLAFGDNVHCF
EEEEEEEHHHHHHHHHHHHCCCEEECCCCEEEEEECCCCCCCCCCEEEEEEEECCCEEEE
FAEPTHSPCMLLGVYTGLHDAISVQDIGIDNLTAADGLAVGRASGFVGRAMERLLDGLYT
EECCCCCCEEEEEEHHCHHHHCEEEECCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHC
LDDQTMYDMLGWLAQEEGIRLEPSALAGMAGPQRICAATVYQQRHGFSQTQLGNATHLVW
CCCHHHHHHHHHHHHCCCCEECHHHHHCCCCHHHHHHHHHHHHHCCCCHHCCCCCEEEEE
ATGGGMVPEDEMEQYLAKGR
ECCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA