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The map label for this gene is resE [H]

Identifier: 193212325

GI number: 193212325

Start: 705269

End: 707059

Strand: Direct

Name: resE [H]

Synonym: Cpar_0658

Alternate gene names: 193212325

Gene position: 705269-707059 (Clockwise)

Preceding gene: 193212324

Following gene: 193212326

Centisome position: 30.81

GC content: 60.47

Gene sequence:

>1791_bases
GTGAAGGCTAAGGTCTCATTCAGACTCGGCCTGGTTTTCGGTCTGATCGTCTTTTTCTCGCTCGCCCTGAGCTACGTGTA
TCAGGGGCGACATCTTCGCGAGGTGGTGTTCAAGACGGTTCGCGCCGGCCTGTTGCACGACCTCAAGCTCAATGCCGGGA
TGCTCGATCAGCGCCCCGACGGCTGGCCGGACATCGCGCTCTCCGACCGCTGGGCGGACAAGGTCGGCAAGGCGCTCGAC
CTTCGCGTGACGCTCATCGACCTCGATGGCCGGGTGATTGGTGACTCCTACATTCCCACGGAAAAAATTCCTTCCATTCC
GAATCATCGGGATCGGGTTGAAATCAAATCGGCGCTCTCCAGCGGGCTGGGCGAATCGAAGCGTTTCAGCGAGACCATCC
GCGAGAACATGCTCTACATGGCCATGCCGGTCGGCAAGCCCGACACCTGGGCCGTCCTCCGGCTGGCGAAACCTCTGCAC
GACATCGGCCAGGTGGAAGCGCAGATCGACCGTGGCATCGAGGGCGGCCTGTTCTGGGCGCTTCTGCTTGCGCTTACTGC
CGGAGGGCTTTCGGCGTTTTTCCTGTCGCGCCCGCTGGGGCGTATTGCCGATGCGGCCGACCGGTTCCTGCATGGCGAAA
CCGAGGTGCAGATTCCCGTAAAGCATGACGATGAGATCGGACGCCTTGCGCGAGCCTTCAACTACCTCTCCGAAGAGATC
GTCAGGCTGACGCGCAAGGAGGAGTGGCTTCGCGAAGTGCTTTCAAGTATTCGCGAGTCGATTATCGTGACCAACGCTTC
GGGCGAAATCGTGCTGGCCAATCCGGCGGCGTCGCGCCTGTTCATGATCGAGGGGGCGCGGAAACGGTCGATTCCAGTCG
ATCACATCGAACTTCCGGAGATGCGGGAGCTGTTCGTGCGTGTGCATGCCCGCCAGAGCGGAATCTACAACGAAGAGCTG
AGCGTTATGACTGCCCGGGGCGAGCGGGTGTTCAAGGTCACCGCCGTGCCGGTCGTGAAGGGCGAGCAATTCGACGGCAC
GGTGCTGGTCATCAACGACATCACCCGCCTGCGCAACCTGGAACGCACCCGCCGCGACTTCGTTTCCAGCGTGTCGCACG
AGTTGCGTACGCCGTTGGCGAGCATCAAGGGCTATACCGAAACCCTGCTCGAAGGCGCGGTCAACGATCCGGAGCATGCC
ACTGCATTTCTGCGCATCATCCAGCAGGAGAGCGAGCAACTCACCGCGCTCATCAACGACGTGCTCGACCTGTCGCGCAT
CGAATCGGGCAAGATCATCTATAATTTTGAGCCGGTCGATGTGAAGCCGGCGCTCGAAAAAACGATGGCGCTGTTCGAGC
CTGCCGCGTCCCGCAAAGGGGTGCGCATCGAGCTGAACGTGCCCGATGGGTTGCCGCCGGTGCTGGCCGACCGGAACTAT
TTCGATATCGTGATGCGCAACCTCATCGACAATGCGGTTAAATACGTCGATGCGAACCGCGGGCGTGTCAGGGTCAGCGC
CTGCAAGGCCGATCAGAACGTCGCTATCGAGGTTTCCGATAACGGCATCGGTATTCCGCAGGCCGATCTGAAGCGGATTT
TCGAGCGCTTCTACCGCGTTGACAAGGCCCGCTCGCGGGAGCTTGCCGGCACTGGTCTCGGACTGTCGATCGTCAAGCAC
ATTCTGCTCGCGCACAAAGGGAATGTCGAGGTGCGCTCAAAAACCAACAGCGGTTCTACTTTTACGGTGACCTTCCCGAT
TGCCGGAAAGGAAGCTGCTTCGAGCACCTGA

Upstream 100 bases:

>100_bases
CACGTCACCCGCCTCCGCGAAAAGCTCGGCGATGCCGGAAAGCTCATCAAAACCGTGCGCGGGCTCGGCTACAAGTTCGA
CGAAGGCGAAGAGGAGTCCG

Downstream 100 bases:

>100_bases
TCATCCCGGTTTCCCTCCTGCGGCCAGGCTTCGGTTAGTTCCGGATTTTTTGTATTAATAAGCACCGAACAGCTTTCGTC
AGATTTGCTGTCGCTTGACC

Product: multi-sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 596; Mature: 596

Protein sequence:

>596_residues
MKAKVSFRLGLVFGLIVFFSLALSYVYQGRHLREVVFKTVRAGLLHDLKLNAGMLDQRPDGWPDIALSDRWADKVGKALD
LRVTLIDLDGRVIGDSYIPTEKIPSIPNHRDRVEIKSALSSGLGESKRFSETIRENMLYMAMPVGKPDTWAVLRLAKPLH
DIGQVEAQIDRGIEGGLFWALLLALTAGGLSAFFLSRPLGRIADAADRFLHGETEVQIPVKHDDEIGRLARAFNYLSEEI
VRLTRKEEWLREVLSSIRESIIVTNASGEIVLANPAASRLFMIEGARKRSIPVDHIELPEMRELFVRVHARQSGIYNEEL
SVMTARGERVFKVTAVPVVKGEQFDGTVLVINDITRLRNLERTRRDFVSSVSHELRTPLASIKGYTETLLEGAVNDPEHA
TAFLRIIQQESEQLTALINDVLDLSRIESGKIIYNFEPVDVKPALEKTMALFEPAASRKGVRIELNVPDGLPPVLADRNY
FDIVMRNLIDNAVKYVDANRGRVRVSACKADQNVAIEVSDNGIGIPQADLKRIFERFYRVDKARSRELAGTGLGLSIVKH
ILLAHKGNVEVRSKTNSGSTFTVTFPIAGKEAASST

Sequences:

>Translated_596_residues
MKAKVSFRLGLVFGLIVFFSLALSYVYQGRHLREVVFKTVRAGLLHDLKLNAGMLDQRPDGWPDIALSDRWADKVGKALD
LRVTLIDLDGRVIGDSYIPTEKIPSIPNHRDRVEIKSALSSGLGESKRFSETIRENMLYMAMPVGKPDTWAVLRLAKPLH
DIGQVEAQIDRGIEGGLFWALLLALTAGGLSAFFLSRPLGRIADAADRFLHGETEVQIPVKHDDEIGRLARAFNYLSEEI
VRLTRKEEWLREVLSSIRESIIVTNASGEIVLANPAASRLFMIEGARKRSIPVDHIELPEMRELFVRVHARQSGIYNEEL
SVMTARGERVFKVTAVPVVKGEQFDGTVLVINDITRLRNLERTRRDFVSSVSHELRTPLASIKGYTETLLEGAVNDPEHA
TAFLRIIQQESEQLTALINDVLDLSRIESGKIIYNFEPVDVKPALEKTMALFEPAASRKGVRIELNVPDGLPPVLADRNY
FDIVMRNLIDNAVKYVDANRGRVRVSACKADQNVAIEVSDNGIGIPQADLKRIFERFYRVDKARSRELAGTGLGLSIVKH
ILLAHKGNVEVRSKTNSGSTFTVTFPIAGKEAASST
>Mature_596_residues
MKAKVSFRLGLVFGLIVFFSLALSYVYQGRHLREVVFKTVRAGLLHDLKLNAGMLDQRPDGWPDIALSDRWADKVGKALD
LRVTLIDLDGRVIGDSYIPTEKIPSIPNHRDRVEIKSALSSGLGESKRFSETIRENMLYMAMPVGKPDTWAVLRLAKPLH
DIGQVEAQIDRGIEGGLFWALLLALTAGGLSAFFLSRPLGRIADAADRFLHGETEVQIPVKHDDEIGRLARAFNYLSEEI
VRLTRKEEWLREVLSSIRESIIVTNASGEIVLANPAASRLFMIEGARKRSIPVDHIELPEMRELFVRVHARQSGIYNEEL
SVMTARGERVFKVTAVPVVKGEQFDGTVLVINDITRLRNLERTRRDFVSSVSHELRTPLASIKGYTETLLEGAVNDPEHA
TAFLRIIQQESEQLTALINDVLDLSRIESGKIIYNFEPVDVKPALEKTMALFEPAASRKGVRIELNVPDGLPPVLADRNY
FDIVMRNLIDNAVKYVDANRGRVRVSACKADQNVAIEVSDNGIGIPQADLKRIFERFYRVDKARSRELAGTGLGLSIVKH
ILLAHKGNVEVRSKTNSGSTFTVTFPIAGKEAASST

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=228, Percent_Identity=33.3333333333333, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1786600, Length=336, Percent_Identity=27.6785714285714, Blast_Score=133, Evalue=4e-32,
Organism=Escherichia coli, GI1789149, Length=232, Percent_Identity=33.1896551724138, Blast_Score=129, Evalue=7e-31,
Organism=Escherichia coli, GI48994928, Length=231, Percent_Identity=35.0649350649351, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1788549, Length=388, Percent_Identity=27.0618556701031, Blast_Score=122, Evalue=6e-29,
Organism=Escherichia coli, GI1788713, Length=546, Percent_Identity=23.4432234432234, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1786912, Length=227, Percent_Identity=32.15859030837, Blast_Score=113, Evalue=4e-26,
Organism=Escherichia coli, GI145693157, Length=234, Percent_Identity=31.1965811965812, Blast_Score=109, Evalue=5e-25,
Organism=Escherichia coli, GI87081816, Length=229, Percent_Identity=30.5676855895196, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI1790346, Length=236, Percent_Identity=29.2372881355932, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1790436, Length=221, Percent_Identity=28.5067873303167, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1786783, Length=246, Percent_Identity=29.6747967479675, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI87082128, Length=233, Percent_Identity=29.1845493562232, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1790861, Length=218, Percent_Identity=30.7339449541284, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787894, Length=249, Percent_Identity=26.1044176706827, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1787374, Length=240, Percent_Identity=28.3333333333333, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1789403, Length=230, Percent_Identity=32.6086956521739, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1789808, Length=240, Percent_Identity=27.5, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI1788279, Length=233, Percent_Identity=24.8927038626609, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1790300, Length=363, Percent_Identity=23.9669421487603, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1790551, Length=246, Percent_Identity=24.390243902439, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 66386; Mature: 66386

Theoretical pI: Translated: 9.07; Mature: 9.07

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAKVSFRLGLVFGLIVFFSLALSYVYQGRHLREVVFKTVRAGLLHDLKLNAGMLDQRPD
CCCEEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
GWPDIALSDRWADKVGKALDLRVTLIDLDGRVIGDSYIPTEKIPSIPNHRDRVEIKSALS
CCCCCCCCCHHHHHHCCEEEEEEEEEECCCEEECCCCCCHHHCCCCCCCCHHHHHHHHHH
SGLGESKRFSETIRENMLYMAMPVGKPDTWAVLRLAKPLHDIGQVEAQIDRGIEGGLFWA
HCCCCHHHHHHHHHHCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
LLLALTAGGLSAFFLSRPLGRIADAADRFLHGETEVQIPVKHDDEIGRLARAFNYLSEEI
HHHHHHHCCHHHHHHHCCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHH
VRLTRKEEWLREVLSSIRESIIVTNASGEIVLANPAASRLFMIEGARKRSIPVDHIELPE
HHHHHHHHHHHHHHHHHHHHEEEECCCCCEEEECCCCCEEEEEECCCCCCCCCCCCCCHH
MRELFVRVHARQSGIYNEELSVMTARGERVFKVTAVPVVKGEQFDGTVLVINDITRLRNL
HHHHHHHHHHHHCCCCCCCHHEEEECCCEEEEEEEEEEEECCCCCCEEEEEECHHHHHHH
ERTRRDFVSSVSHELRTPLASIKGYTETLLEGAVNDPEHATAFLRIIQQESEQLTALIND
HHHHHHHHHHHHHHHHCHHHHHCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VLDLSRIESGKIIYNFEPVDVKPALEKTMALFEPAASRKGVRIELNVPDGLPPVLADRNY
HHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHCCCCH
FDIVMRNLIDNAVKYVDANRGRVRVSACKADQNVAIEVSDNGIGIPQADLKRIFERFYRV
HHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEEECCCCCCCCHHHHHHHHHHHHHH
DKARSRELAGTGLGLSIVKHILLAHKGNVEVRSKTNSGSTFTVTFPIAGKEAASST
HHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCEEEEEEEECCCCCCCCC
>Mature Secondary Structure
MKAKVSFRLGLVFGLIVFFSLALSYVYQGRHLREVVFKTVRAGLLHDLKLNAGMLDQRPD
CCCEEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
GWPDIALSDRWADKVGKALDLRVTLIDLDGRVIGDSYIPTEKIPSIPNHRDRVEIKSALS
CCCCCCCCCHHHHHHCCEEEEEEEEEECCCEEECCCCCCHHHCCCCCCCCHHHHHHHHHH
SGLGESKRFSETIRENMLYMAMPVGKPDTWAVLRLAKPLHDIGQVEAQIDRGIEGGLFWA
HCCCCHHHHHHHHHHCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
LLLALTAGGLSAFFLSRPLGRIADAADRFLHGETEVQIPVKHDDEIGRLARAFNYLSEEI
HHHHHHHCCHHHHHHHCCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHH
VRLTRKEEWLREVLSSIRESIIVTNASGEIVLANPAASRLFMIEGARKRSIPVDHIELPE
HHHHHHHHHHHHHHHHHHHHEEEECCCCCEEEECCCCCEEEEEECCCCCCCCCCCCCCHH
MRELFVRVHARQSGIYNEELSVMTARGERVFKVTAVPVVKGEQFDGTVLVINDITRLRNL
HHHHHHHHHHHHCCCCCCCHHEEEECCCEEEEEEEEEEEECCCCCCEEEEEECHHHHHHH
ERTRRDFVSSVSHELRTPLASIKGYTETLLEGAVNDPEHATAFLRIIQQESEQLTALIND
HHHHHHHHHHHHHHHHCHHHHHCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VLDLSRIESGKIIYNFEPVDVKPALEKTMALFEPAASRKGVRIELNVPDGLPPVLADRNY
HHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHCCCCH
FDIVMRNLIDNAVKYVDANRGRVRVSACKADQNVAIEVSDNGIGIPQADLKRIFERFYRV
HHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEEECCCCCCCCHHHHHHHHHHHHHH
DKARSRELAGTGLGLSIVKHILLAHKGNVEVRSKTNSGSTFTVTFPIAGKEAASST
HHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCEEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]