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The map label for this gene is phoP [H]

Identifier: 193212324

GI number: 193212324

Start: 704569

End: 705279

Strand: Direct

Name: phoP [H]

Synonym: Cpar_0657

Alternate gene names: 193212324

Gene position: 704569-705279 (Clockwise)

Preceding gene: 193212323

Following gene: 193212325

Centisome position: 30.78

GC content: 60.48

Gene sequence:

>711_bases
ATGTCTGACACTACCATTTTGATCGTCGAAGATGACCGGAACCTTGCCGGGCTCCTGAAGTACAACCTCGAAAAAGCGGG
CTACAGCTGCCTGCACGCCGCCACTGGAGAGGAGGCGCTCGAACAGCTTCGGCAGCATGCGGTCAATATGGTGCTGCTCG
ACATCATGCTGCCCGGCATCGACGGCTTTGAAGTGTGCCGCCGGATCCGGCAGGATGTGCAGTGGAGCGACCTGCCCATC
GTGATGCTGACCGCCAAGGGCGAGGAGATCGACAAGGTGTTCGGCTTCGAGCTTGGCATCGACGATTACGTCGTCAAGCC
CTTCAGTCCTCGCGAACTGAACCTCAGAATTCGCGCCATCCTGAAGCGCGACCGGCGCAACCGCAGCAACGTGCAGGAGG
TGCTTCGCGCCGATGGCATCGAAATCGACATCGGCAAGCATATCGCCAAGCTCGACGGCCAGCCGCTGGCGCTTACCCTC
ATGGAGTTCAAGCTGCTCGCCCTTTTGCTCAAACGCAGAGGGCAGGCGCAGACGCGCGAAGTGCTCCTGAGCGACGTGTG
GGATGTGGACAAGAGCATCAACACCCGCACCATCGACACCCACGTCACCCGCCTCCGCGAAAAGCTCGGCGATGCCGGAA
AGCTCATCAAAACCGTGCGCGGGCTCGGCTACAAGTTCGACGAAGGCGAAGAGGAGTCCGGTGAAGGCTAA

Upstream 100 bases:

>100_bases
CACTGCCGACAGGCGCAACCGCCACTCGTCGAATATGAACAGGGCCATCAGGCGGCCTGCTGGAAAATCGCCTGAACGCA
ACGAAAGCTATCAAAGCAGC

Downstream 100 bases:

>100_bases
GGTCTCATTCAGACTCGGCCTGGTTTTCGGTCTGATCGTCTTTTTCTCGCTCGCCCTGAGCTACGTGTATCAGGGGCGAC
ATCTTCGCGAGGTGGTGTTC

Product: winged helix family two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 236; Mature: 235

Protein sequence:

>236_residues
MSDTTILIVEDDRNLAGLLKYNLEKAGYSCLHAATGEEALEQLRQHAVNMVLLDIMLPGIDGFEVCRRIRQDVQWSDLPI
VMLTAKGEEIDKVFGFELGIDDYVVKPFSPRELNLRIRAILKRDRRNRSNVQEVLRADGIEIDIGKHIAKLDGQPLALTL
MEFKLLALLLKRRGQAQTREVLLSDVWDVDKSINTRTIDTHVTRLREKLGDAGKLIKTVRGLGYKFDEGEEESGEG

Sequences:

>Translated_236_residues
MSDTTILIVEDDRNLAGLLKYNLEKAGYSCLHAATGEEALEQLRQHAVNMVLLDIMLPGIDGFEVCRRIRQDVQWSDLPI
VMLTAKGEEIDKVFGFELGIDDYVVKPFSPRELNLRIRAILKRDRRNRSNVQEVLRADGIEIDIGKHIAKLDGQPLALTL
MEFKLLALLLKRRGQAQTREVLLSDVWDVDKSINTRTIDTHVTRLREKLGDAGKLIKTVRGLGYKFDEGEEESGEG
>Mature_235_residues
SDTTILIVEDDRNLAGLLKYNLEKAGYSCLHAATGEEALEQLRQHAVNMVLLDIMLPGIDGFEVCRRIRQDVQWSDLPIV
MLTAKGEEIDKVFGFELGIDDYVVKPFSPRELNLRIRAILKRDRRNRSNVQEVLRADGIEIDIGKHIAKLDGQPLALTLM
EFKLLALLLKRRGQAQTREVLLSDVWDVDKSINTRTIDTHVTRLREKLGDAGKLIKTVRGLGYKFDEGEEESGEG

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=224, Percent_Identity=37.5, Blast_Score=165, Evalue=3e-42,
Organism=Escherichia coli, GI1788394, Length=225, Percent_Identity=42.6666666666667, Blast_Score=163, Evalue=9e-42,
Organism=Escherichia coli, GI1790860, Length=230, Percent_Identity=37.8260869565217, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1789809, Length=231, Percent_Identity=35.9307359307359, Blast_Score=144, Evalue=6e-36,
Organism=Escherichia coli, GI2367329, Length=227, Percent_Identity=42.2907488986784, Blast_Score=143, Evalue=8e-36,
Organism=Escherichia coli, GI1790552, Length=226, Percent_Identity=37.1681415929204, Blast_Score=136, Evalue=9e-34,
Organism=Escherichia coli, GI1789402, Length=223, Percent_Identity=35.4260089686099, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI87082012, Length=223, Percent_Identity=35.4260089686099, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1790863, Length=236, Percent_Identity=33.4745762711864, Blast_Score=127, Evalue=8e-31,
Organism=Escherichia coli, GI1786784, Length=224, Percent_Identity=33.9285714285714, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI1786911, Length=226, Percent_Identity=30.9734513274336, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1787229, Length=224, Percent_Identity=31.6964285714286, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1787375, Length=225, Percent_Identity=31.1111111111111, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI145693140, Length=234, Percent_Identity=32.0512820512821, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1790299, Length=108, Percent_Identity=31.4814814814815, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1788191, Length=119, Percent_Identity=28.5714285714286, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26709; Mature: 26578

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDTTILIVEDDRNLAGLLKYNLEKAGYSCLHAATGEEALEQLRQHAVNMVLLDIMLPGI
CCCCEEEEEECCCCHHHHHHHHHHHHCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCC
DGFEVCRRIRQDVQWSDLPIVMLTAKGEEIDKVFGFELGIDDYVVKPFSPRELNLRIRAI
CHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHH
LKRDRRNRSNVQEVLRADGIEIDIGKHIAKLDGQPLALTLMEFKLLALLLKRRGQAQTRE
HHHHCCCHHHHHHHHHHCCCEEEHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHH
VLLSDVWDVDKSINTRTIDTHVTRLREKLGDAGKLIKTVRGLGYKFDEGEEESGEG
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SDTTILIVEDDRNLAGLLKYNLEKAGYSCLHAATGEEALEQLRQHAVNMVLLDIMLPGI
CCCEEEEEECCCCHHHHHHHHHHHHCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCC
DGFEVCRRIRQDVQWSDLPIVMLTAKGEEIDKVFGFELGIDDYVVKPFSPRELNLRIRAI
CHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHH
LKRDRRNRSNVQEVLRADGIEIDIGKHIAKLDGQPLALTLMEFKLLALLLKRRGQAQTRE
HHHHCCCHHHHHHHHHHCCCEEEHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHH
VLLSDVWDVDKSINTRTIDTHVTRLREKLGDAGKLIKTVRGLGYKFDEGEEESGEG
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]