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The map label for this gene is yacO [H]

Identifier: 193212230

GI number: 193212230

Start: 605996

End: 606769

Strand: Direct

Name: yacO [H]

Synonym: Cpar_0561

Alternate gene names: 193212230

Gene position: 605996-606769 (Clockwise)

Preceding gene: 193212228

Following gene: 193212231

Centisome position: 26.47

GC content: 59.56

Gene sequence:

>774_bases
TTGGACAGAACAGACCACGCCGAAATCCCGGCTCCCGAACCTCGCGAACAGGTTGTTTATGGCCGTAACGCCGTCATCGA
GCTGTTGCAGTCGAAACCTGAGAGCGTCGAGAAAATTTACCTCCAGTTCAACACCAGCCATCCCAAGCTCAAGGAGATCG
TCATCACGGCTCGTCGCCTTAAGATTCCCTGTGGTAAGGCGCGCATGGAGAAGCTCACGCTCATTTCCGGTACGGCCAAG
AACCAGGGCGTCTGCGCGCTGCTGACCAGCGTGACATTCTACACGCTCGACGAGGTGCTTGCCGCACCGCGCAACAGCTC
GCCGCTGCTGGTGATTTTGCAGGGGCTTGAAGATCCACATAACGTCGGGGCTATCATCCGCACTGCCGAGGCTGTGGCTG
CTGACTCGGTCATCATGATCGAAGGCAAGGGCGCACCGATCAGCGCCACGGTGCACAAGGCATCGGCGGGCGCGCTTTCG
CACATGCGGGTCTGCAAGGTCAAGAGCCTGGTCAAGACGCTTGACCTGTTGCACGAGCGCGGATTCAGCATCGTGGCCGC
TGACATGGAGGCTGAACATAATCACACGGACATCGACTGGAAGCGTCCCACAGTGCTCGTGATGGGGGCAGAGGGCAAAG
GGCTCGGCTCCGAAACCCGCAAACGCTGCGACCAGATCGTGCGCATTCCGATGGCCGGCTGCGTCGAATCGCTCAATGTC
AGCGTGGCTGCCGGGGTGATGCTGTACGAAGCGATGCGTCAAAGGTTAGGTTGA

Upstream 100 bases:

>100_bases
CAATCGTGAATACTCTTATAGCATTTGCTTGTTGATACGCTTTTTTTGCATCTAACGAGCAGTCGGGGCGCATGCCCGGC
AAACCAAACTTTTTTGATTT

Downstream 100 bases:

>100_bases
AGACCAGTCGGATCATACGTCCAATCCGACCGATCTTTCCGCGATTCTGAAAAAATGTTACCTTCAAGTTCATTTGTAAC
TCTTCAATTGCATAGCAACT

Product: RNA methyltransferase, TrmH family, group 3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MDRTDHAEIPAPEPREQVVYGRNAVIELLQSKPESVEKIYLQFNTSHPKLKEIVITARRLKIPCGKARMEKLTLISGTAK
NQGVCALLTSVTFYTLDEVLAAPRNSSPLLVILQGLEDPHNVGAIIRTAEAVAADSVIMIEGKGAPISATVHKASAGALS
HMRVCKVKSLVKTLDLLHERGFSIVAADMEAEHNHTDIDWKRPTVLVMGAEGKGLGSETRKRCDQIVRIPMAGCVESLNV
SVAAGVMLYEAMRQRLG

Sequences:

>Translated_257_residues
MDRTDHAEIPAPEPREQVVYGRNAVIELLQSKPESVEKIYLQFNTSHPKLKEIVITARRLKIPCGKARMEKLTLISGTAK
NQGVCALLTSVTFYTLDEVLAAPRNSSPLLVILQGLEDPHNVGAIIRTAEAVAADSVIMIEGKGAPISATVHKASAGALS
HMRVCKVKSLVKTLDLLHERGFSIVAADMEAEHNHTDIDWKRPTVLVMGAEGKGLGSETRKRCDQIVRIPMAGCVESLNV
SVAAGVMLYEAMRQRLG
>Mature_257_residues
MDRTDHAEIPAPEPREQVVYGRNAVIELLQSKPESVEKIYLQFNTSHPKLKEIVITARRLKIPCGKARMEKLTLISGTAK
NQGVCALLTSVTFYTLDEVLAAPRNSSPLLVILQGLEDPHNVGAIIRTAEAVAADSVIMIEGKGAPISATVHKASAGALS
HMRVCKVKSLVKTLDLLHERGFSIVAADMEAEHNHTDIDWKRPTVLVMGAEGKGLGSETRKRCDQIVRIPMAGCVESLNV
SVAAGVMLYEAMRQRLG

Specific function: Unknown

COG id: COG0566

COG function: function code J; rRNA methylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase TrmH family [H]

Homologues:

Organism=Homo sapiens, GI40068479, Length=265, Percent_Identity=29.811320754717, Blast_Score=109, Evalue=2e-24,
Organism=Escherichia coli, GI1790623, Length=242, Percent_Identity=34.297520661157, Blast_Score=137, Evalue=9e-34,
Organism=Escherichia coli, GI1790083, Length=159, Percent_Identity=38.3647798742138, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1788935, Length=239, Percent_Identity=27.6150627615063, Blast_Score=87, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17555908, Length=260, Percent_Identity=26.1538461538462, Blast_Score=76, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6324775, Length=165, Percent_Identity=28.4848484848485, Blast_Score=72, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004441
- InterPro:   IPR001537
- InterPro:   IPR013123 [H]

Pfam domain/function: PF00588 SpoU_methylase; PF08032 SpoU_sub_bind [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 27937; Mature: 27937

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRTDHAEIPAPEPREQVVYGRNAVIELLQSKPESVEKIYLQFNTSHPKLKEIVITARRL
CCCCCCCCCCCCCCHHHEECCHHHHHHHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHHH
KIPCGKARMEKLTLISGTAKNQGVCALLTSVTFYTLDEVLAAPRNSSPLLVILQGLEDPH
CCCCCHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCC
NVGAIIRTAEAVAADSVIMIEGKGAPISATVHKASAGALSHMRVCKVKSLVKTLDLLHER
HHHHHHHHHHHHHCCCEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHC
GFSIVAADMEAEHNHTDIDWKRPTVLVMGAEGKGLGSETRKRCDQIVRIPMAGCVESLNV
CCEEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCHHHHHHHCCH
SVAAGVMLYEAMRQRLG
HHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDRTDHAEIPAPEPREQVVYGRNAVIELLQSKPESVEKIYLQFNTSHPKLKEIVITARRL
CCCCCCCCCCCCCCHHHEECCHHHHHHHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHHH
KIPCGKARMEKLTLISGTAKNQGVCALLTSVTFYTLDEVLAAPRNSSPLLVILQGLEDPH
CCCCCHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCC
NVGAIIRTAEAVAADSVIMIEGKGAPISATVHKASAGALSHMRVCKVKSLVKTLDLLHER
HHHHHHHHHHHHHCCCEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHC
GFSIVAADMEAEHNHTDIDWKRPTVLVMGAEGKGLGSETRKRCDQIVRIPMAGCVESLNV
CCEEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCHHHHHHHCCH
SVAAGVMLYEAMRQRLG
HHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 7510287; 3145906 [H]