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The map label for this gene is ruvB [H]

Identifier: 193212227

GI number: 193212227

Start: 599396

End: 600424

Strand: Direct

Name: ruvB [H]

Synonym: Cpar_0558

Alternate gene names: 193212227

Gene position: 599396-600424 (Clockwise)

Preceding gene: 193212226

Following gene: 193212228

Centisome position: 26.18

GC content: 60.45

Gene sequence:

>1029_bases
GTGAGGATTGAAGCCCTGAATACCGCCCCCGACGCGACGGAAGTCCGGTTCGAGGAGCAGATAAGGCCGCAGAGCATGAG
CGATTTTGCCGGTCAGAAAAAGCTGACCGACAATCTGAAGGTGTTCATCACTGCGGCGCGAAAACGCGGCGATGCGCTCG
ACCATGTGCTGCTTTCCGGGCCGCCAGGACTTGGCAAAACCACGCTTGCACACATCATCGCCGCCGAGATGGGTGGGGGC
ATCAAGATCACCTCCGGCCCGCTGATCGACAAGGCGGGTAATCTGGCCGGGCTGCTCACCAGTCTCAAAAAGGGAGACAT
CCTTTTTATCGACGAAATCCACCGTTTGGCTCCTGCGGTCGAGGAGTATCTCTACTCGGCGATGGAGGATTACCGGATCG
ACATTCTGCTCGACAGCGGTCCGGCTTCCCGCGCAGTGCAGCTCAAGCTCGAACCCTTCACGCTGGTCGGCGCGACTACG
AGATCCGGTCTCTTGACCTCGCCGCTCCGGGCCCGTTTCGGCATCAACAGTCGCCTTGATTACTACAGTCCGGAGTTGCT
GCAAAGCATCATCGTCCGTGCGGCGGGCATCCTGAATATCGGTGTCGATGAGGACGCGGCCATGGAGATCGCCCGCCGCT
CACGCGGCACCCCGCGTATCGCCAACCGCCTTCTGCGGCGCGCGCGCGATTTCGCACAGGTGGCCAATGAAGCTTCGATC
TCGCTTGCCGTCGCCCGGCGGACACTTGAATCGCTTGAAATCGATGAAGGTGGTCTCGACGACATGGACAAGAAAATTCT
CGAAGCGATCGTGCGCAAATTCAACGGCGGCCCGGTCGGCGTGGCGTCGCTGGCCGTTTCGGTCGGCGAGGAGCAGGATA
CCATCGAGGAGGTCTATGAGCCCTACCTTATTCAGGTCGGCTATCTTGCCCGAACTCCGCGCGGTCGGGTGGCGACCAGG
CTTGCCATGCAGCGCTTTTCCTACCCTGGCATGCAGGATCATGGGCCGCTCTTCGACCACAATTCATGA

Upstream 100 bases:

>100_bases
GTCTCCGGCACCATGATCGTGCTGGGCAATCTGCTGGCCGACGTGCTGTATGCCGTGGTCGATCCGCGGATCAAACTGTG
AACCAAAATGATGAGTCTGA

Downstream 100 bases:

>100_bases
CGCCTGAAGCGAACAACAGTAAGCCTCGTGCTGGTCGTCGGCTCTTCATGTCGGCCTTGACTGCCTTGTCGCTGCTCTCC
GCTCCTGCAGGCATGAATGC

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MRIEALNTAPDATEVRFEEQIRPQSMSDFAGQKKLTDNLKVFITAARKRGDALDHVLLSGPPGLGKTTLAHIIAAEMGGG
IKITSGPLIDKAGNLAGLLTSLKKGDILFIDEIHRLAPAVEEYLYSAMEDYRIDILLDSGPASRAVQLKLEPFTLVGATT
RSGLLTSPLRARFGINSRLDYYSPELLQSIIVRAAGILNIGVDEDAAMEIARRSRGTPRIANRLLRRARDFAQVANEASI
SLAVARRTLESLEIDEGGLDDMDKKILEAIVRKFNGGPVGVASLAVSVGEEQDTIEEVYEPYLIQVGYLARTPRGRVATR
LAMQRFSYPGMQDHGPLFDHNS

Sequences:

>Translated_342_residues
MRIEALNTAPDATEVRFEEQIRPQSMSDFAGQKKLTDNLKVFITAARKRGDALDHVLLSGPPGLGKTTLAHIIAAEMGGG
IKITSGPLIDKAGNLAGLLTSLKKGDILFIDEIHRLAPAVEEYLYSAMEDYRIDILLDSGPASRAVQLKLEPFTLVGATT
RSGLLTSPLRARFGINSRLDYYSPELLQSIIVRAAGILNIGVDEDAAMEIARRSRGTPRIANRLLRRARDFAQVANEASI
SLAVARRTLESLEIDEGGLDDMDKKILEAIVRKFNGGPVGVASLAVSVGEEQDTIEEVYEPYLIQVGYLARTPRGRVATR
LAMQRFSYPGMQDHGPLFDHNS
>Mature_342_residues
MRIEALNTAPDATEVRFEEQIRPQSMSDFAGQKKLTDNLKVFITAARKRGDALDHVLLSGPPGLGKTTLAHIIAAEMGGG
IKITSGPLIDKAGNLAGLLTSLKKGDILFIDEIHRLAPAVEEYLYSAMEDYRIDILLDSGPASRAVQLKLEPFTLVGATT
RSGLLTSPLRARFGINSRLDYYSPELLQSIIVRAAGILNIGVDEDAAMEIARRSRGTPRIANRLLRRARDFAQVANEASI
SLAVARRTLESLEIDEGGLDDMDKKILEAIVRKFNGGPVGVASLAVSVGEEQDTIEEVYEPYLIQVGYLARTPRGRVATR
LAMQRFSYPGMQDHGPLFDHNS

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family [H]

Homologues:

Organism=Escherichia coli, GI1788167, Length=306, Percent_Identity=56.2091503267974, Blast_Score=365, Evalue=1e-102,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- ProDom:   PD005323 [H]

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 37338; Mature: 37338

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIEALNTAPDATEVRFEEQIRPQSMSDFAGQKKLTDNLKVFITAARKRGDALDHVLLSG
CEECCCCCCCCHHHHHHHHHCCCCCHHHHHCCHHHHCCCEEEEEEHHHCCCHHHHHHCCC
PPGLGKTTLAHIIAAEMGGGIKITSGPLIDKAGNLAGLLTSLKKGDILFIDEIHRLAPAV
CCCCCHHHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHCCCCEEEHHHHHHHHHHH
EEYLYSAMEDYRIDILLDSGPASRAVQLKLEPFTLVGATTRSGLLTSPLRARFGINSRLD
HHHHHHHHHCCEEEEEECCCCCCCEEEEEECCEEEEECCCCCCCCCCCHHHHCCCCCCCC
YYSPELLQSIIVRAAGILNIGVDEDAAMEIARRSRGTPRIANRLLRRARDFAQVANEASI
CCCHHHHHHHHHHHHHHEECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
SLAVARRTLESLEIDEGGLDDMDKKILEAIVRKFNGGPVGVASLAVSVGEEQDTIEEVYE
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCHHHHHHHCC
PYLIQVGYLARTPRGRVATRLAMQRFSYPGMQDHGPLFDHNS
CCEEEEHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRIEALNTAPDATEVRFEEQIRPQSMSDFAGQKKLTDNLKVFITAARKRGDALDHVLLSG
CEECCCCCCCCHHHHHHHHHCCCCCHHHHHCCHHHHCCCEEEEEEHHHCCCHHHHHHCCC
PPGLGKTTLAHIIAAEMGGGIKITSGPLIDKAGNLAGLLTSLKKGDILFIDEIHRLAPAV
CCCCCHHHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHCCCCEEEHHHHHHHHHHH
EEYLYSAMEDYRIDILLDSGPASRAVQLKLEPFTLVGATTRSGLLTSPLRARFGINSRLD
HHHHHHHHHCCEEEEEECCCCCCCEEEEEECCEEEEECCCCCCCCCCCHHHHCCCCCCCC
YYSPELLQSIIVRAAGILNIGVDEDAAMEIARRSRGTPRIANRLLRRARDFAQVANEASI
CCCHHHHHHHHHHHHHHEECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
SLAVARRTLESLEIDEGGLDDMDKKILEAIVRKFNGGPVGVASLAVSVGEEQDTIEEVYE
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCHHHHHHHCC
PYLIQVGYLARTPRGRVATRLAMQRFSYPGMQDHGPLFDHNS
CCEEEEHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12093901 [H]