Click here to switch to the map view.

The map label for this gene is appB [H]

Identifier: 193212226

GI number: 193212226

Start: 598411

End: 599376

Strand: Direct

Name: appB [H]

Synonym: Cpar_0557

Alternate gene names: 193212226

Gene position: 598411-599376 (Clockwise)

Preceding gene: 193212225

Following gene: 193212227

Centisome position: 26.14

GC content: 59.11

Gene sequence:

>966_bases
ATGCTGAAGTATATCCTGAAACGGCTGTTGATTGCCGTGCCGCTCGTGTTCGGGGTGCTGACCCTGACCTTTTTTATCAT
CCGGCTTGCGCCCGGCGATCCCGCGGCGTTTTTCATCCAGCCGGGCATCAGCCCCAACGTGGCCGAGCAGATTCGCCAGC
AGTACGGGCTGAACGATCCGCTGCCGGTGCAGTACATCAAGTGGCTTGGCAACGTGCTGCAGGGGGACTTCGGTCGCAGC
TTCAGCCGCGCGCAGCAGCCTGTGTTCGAGGTGATTTCGCAGGCGCTGCCGGTCACGATGACCATCGCCGTGTTGACACT
CATCGCCAACTTCGTGTTCGGTATCATTATCGGCGTCATCTCGGCGGTCAAACAGAACAGCTTTTCCGATCGCTTCCTGA
CGGTTACGGCGCTCTTTTTCTACTCGATGCCGGAGTTCTGGCTCGCCCTGATGATGATTATTCTGTTCGCCCTGAAATGG
CCGCTTTTTCCGGTCTCCGGCTTGAACGAGGTGGGGGCGGAGAGTTATGGCGCGTTCGGCTTCATCATGGACCGGATCTG
GCATCTTGTTTTGCCGGTTACGGTGCTCAGCATCAACGGCGCGGCGGGCATCGCGCGCTACGTGCGGGGCAGCATGCTGG
AGGTGATCCGGCAGGACTATATCCGCACGGCGCGGGCCAAGGGGCTGAGCGAGCGGGTGGTGATTATCAAACACGCCCTG
CGCAACGCCCTTCTTCCTGTGGTTACGCTGATGGGTAGCTCGCTACCGTTCATCTTCAGTGGCGCACTCTTTATCGAAGT
GATCTTCGCTTTTCCAGGCATGGGCCGCGTTACGGTCGAGGCGATTTTCGCCCGTGATTATCCGCTGATTATCGCCAACA
CCTTCGTCTCCGGCACCATGATCGTGCTGGGCAATCTGCTGGCCGACGTGCTGTATGCCGTGGTCGATCCGCGGATCAAA
CTGTGA

Upstream 100 bases:

>100_bases
AACAAGCGGATTCAGGGCGAGAAGCTCAACATCTCAGGCAGTTTCTACAATATCGACGACTGGACTTTGAGGCCGTCGTC
ATCGATTGCGCCGTAACGGT

Downstream 100 bases:

>100_bases
ACCAAAATGATGAGTCTGAGTGAGGATTGAAGCCCTGAATACCGCCCCCGACGCGACGGAAGTCCGGTTCGAGGAGCAGA
TAAGGCCGCAGAGCATGAGC

Product: binding-protein-dependent transport systems inner membrane component

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MLKYILKRLLIAVPLVFGVLTLTFFIIRLAPGDPAAFFIQPGISPNVAEQIRQQYGLNDPLPVQYIKWLGNVLQGDFGRS
FSRAQQPVFEVISQALPVTMTIAVLTLIANFVFGIIIGVISAVKQNSFSDRFLTVTALFFYSMPEFWLALMMIILFALKW
PLFPVSGLNEVGAESYGAFGFIMDRIWHLVLPVTVLSINGAAGIARYVRGSMLEVIRQDYIRTARAKGLSERVVIIKHAL
RNALLPVVTLMGSSLPFIFSGALFIEVIFAFPGMGRVTVEAIFARDYPLIIANTFVSGTMIVLGNLLADVLYAVVDPRIK
L

Sequences:

>Translated_321_residues
MLKYILKRLLIAVPLVFGVLTLTFFIIRLAPGDPAAFFIQPGISPNVAEQIRQQYGLNDPLPVQYIKWLGNVLQGDFGRS
FSRAQQPVFEVISQALPVTMTIAVLTLIANFVFGIIIGVISAVKQNSFSDRFLTVTALFFYSMPEFWLALMMIILFALKW
PLFPVSGLNEVGAESYGAFGFIMDRIWHLVLPVTVLSINGAAGIARYVRGSMLEVIRQDYIRTARAKGLSERVVIIKHAL
RNALLPVVTLMGSSLPFIFSGALFIEVIFAFPGMGRVTVEAIFARDYPLIIANTFVSGTMIVLGNLLADVLYAVVDPRIK
L
>Mature_321_residues
MLKYILKRLLIAVPLVFGVLTLTFFIIRLAPGDPAAFFIQPGISPNVAEQIRQQYGLNDPLPVQYIKWLGNVLQGDFGRS
FSRAQQPVFEVISQALPVTMTIAVLTLIANFVFGIIIGVISAVKQNSFSDRFLTVTALFFYSMPEFWLALMMIILFALKW
PLFPVSGLNEVGAESYGAFGFIMDRIWHLVLPVTVLSINGAAGIARYVRGSMLEVIRQDYIRTARAKGLSERVVIIKHAL
RNALLPVVTLMGSSLPFIFSGALFIEVIFAFPGMGRVTVEAIFARDYPLIIANTFVSGTMIVLGNLLADVLYAVVDPRIK
L

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=337, Percent_Identity=40.0593471810089, Blast_Score=236, Evalue=1e-63,
Organism=Escherichia coli, GI1787053, Length=320, Percent_Identity=37.5, Blast_Score=219, Evalue=2e-58,
Organism=Escherichia coli, GI1787497, Length=320, Percent_Identity=38.125, Blast_Score=219, Evalue=2e-58,
Organism=Escherichia coli, GI1789888, Length=323, Percent_Identity=34.6749226006192, Blast_Score=188, Evalue=4e-49,
Organism=Escherichia coli, GI1788504, Length=361, Percent_Identity=29.9168975069252, Blast_Score=179, Evalue=3e-46,
Organism=Escherichia coli, GI1787761, Length=327, Percent_Identity=35.7798165137615, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1787550, Length=269, Percent_Identity=30.8550185873606, Blast_Score=147, Evalue=7e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 35522; Mature: 35522

Theoretical pI: Translated: 10.12; Mature: 10.12

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKYILKRLLIAVPLVFGVLTLTFFIIRLAPGDPAAFFIQPGISPNVAEQIRQQYGLNDP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHCCCCCC
LPVQYIKWLGNVLQGDFGRSFSRAQQPVFEVISQALPVTMTIAVLTLIANFVFGIIIGVI
CHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAVKQNSFSDRFLTVTALFFYSMPEFWLALMMIILFALKWPLFPVSGLNEVGAESYGAFG
HHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHCHHHHHHHH
FIMDRIWHLVLPVTVLSINGAAGIARYVRGSMLEVIRQDYIRTARAKGLSERVVIIKHAL
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
RNALLPVVTLMGSSLPFIFSGALFIEVIFAFPGMGRVTVEAIFARDYPLIIANTFVSGTM
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEHHHHHHHH
IVLGNLLADVLYAVVDPRIKL
HHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MLKYILKRLLIAVPLVFGVLTLTFFIIRLAPGDPAAFFIQPGISPNVAEQIRQQYGLNDP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHCCCCCC
LPVQYIKWLGNVLQGDFGRSFSRAQQPVFEVISQALPVTMTIAVLTLIANFVFGIIIGVI
CHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAVKQNSFSDRFLTVTALFFYSMPEFWLALMMIILFALKWPLFPVSGLNEVGAESYGAFG
HHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHCHHHHHHHH
FIMDRIWHLVLPVTVLSINGAAGIARYVRGSMLEVIRQDYIRTARAKGLSERVVIIKHAL
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
RNALLPVVTLMGSSLPFIFSGALFIEVIFAFPGMGRVTVEAIFARDYPLIIANTFVSGTM
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEHHHHHHHH
IVLGNLLADVLYAVVDPRIKL
HHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]