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The map label for this gene is yhcW [H]

Identifier: 193212166

GI number: 193212166

Start: 531431

End: 532096

Strand: Direct

Name: yhcW [H]

Synonym: Cpar_0497

Alternate gene names: 193212166

Gene position: 531431-532096 (Clockwise)

Preceding gene: 193212165

Following gene: 193212168

Centisome position: 23.21

GC content: 61.41

Gene sequence:

>666_bases
ATGATCGAAGCGATTCTCTGGGATAATGACGGGCTTTTGGTTGACAGTGAGACGGTGTTCTTCGAAATGACGCGGCGCTT
TTTCGCTGATGCCGGATTGACGATCGATGAGGAGTTCTGGGGCATCGAGTATCTCGGTAACGCCCGGCACAGCGGCGAGC
TGGCTCGTGAACTTGGCCTTGCTGAAGAGCTGGTGCGTCCACTGCTTGACCGGCGCAACGCGGCGTTTGTCGAGCGCTTG
CAGCAGCCCGTGCCGTTGATGCCGAAGGTGCGCGAAACCATCGAAGCACTCTCCGGCACGGTTCGGCTGGCGGTCGTGAC
TGGCAGTGACCGCGACAAGGTGATGCTGATGCACGCGGCGCATGGCCTGCTCGACCATTTCGAGGTGATTGTGACCAGTG
ACGAGGTCAAAAACCCAAAACCTCATCCGGAACCGTATTTCAAAGCGATGGAGCTGCTCGGCGTTGAGCCGGAGCGCTGC
CTGGCGGTCGAGGATTCGCGTCGCGGGCTCGATTCAGCGGTGGCTGCCGGGCTGCGTTGCATCGCGGTGCCCAACGCGCT
GACCCGCGTGCAGCGGTTCGATAGCGCACATGCGGTCGAGGCTGATGTATCCGGCGTGCTGAAGCATGTCAACGCCGGAA
AGTGCCCGGCCGGGGGAGGTTGGTAA

Upstream 100 bases:

>100_bases
CACATAGGTCTGCCCCTACAAGAAATTCATAATGACGAGGTTCGATCCCGATTCCAATTCGGATCACGGGAAAAACCATT
ACAAAGACGTAGCTGACTTT

Downstream 100 bases:

>100_bases
GCCCCTCAGATCTTTTCAACTTTACTGCTCAGCACACGGTCGATCGCGCGGAGGAAGTCGTCGATGCCGAACGGCTTCTG
GATAAAATCCACTCCATCCC

Product: HAD-superfamily hydrolase

Products: Beta-D-Glucose 6- Phosphate. [C]

Alternate protein names: NA

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MIEAILWDNDGLLVDSETVFFEMTRRFFADAGLTIDEEFWGIEYLGNARHSGELARELGLAEELVRPLLDRRNAAFVERL
QQPVPLMPKVRETIEALSGTVRLAVVTGSDRDKVMLMHAAHGLLDHFEVIVTSDEVKNPKPHPEPYFKAMELLGVEPERC
LAVEDSRRGLDSAVAAGLRCIAVPNALTRVQRFDSAHAVEADVSGVLKHVNAGKCPAGGGW

Sequences:

>Translated_221_residues
MIEAILWDNDGLLVDSETVFFEMTRRFFADAGLTIDEEFWGIEYLGNARHSGELARELGLAEELVRPLLDRRNAAFVERL
QQPVPLMPKVRETIEALSGTVRLAVVTGSDRDKVMLMHAAHGLLDHFEVIVTSDEVKNPKPHPEPYFKAMELLGVEPERC
LAVEDSRRGLDSAVAAGLRCIAVPNALTRVQRFDSAHAVEADVSGVLKHVNAGKCPAGGGW
>Mature_221_residues
MIEAILWDNDGLLVDSETVFFEMTRRFFADAGLTIDEEFWGIEYLGNARHSGELARELGLAEELVRPLLDRRNAAFVERL
QQPVPLMPKVRETIEALSGTVRLAVVTGSDRDKVMLMHAAHGLLDHFEVIVTSDEVKNPKPHPEPYFKAMELLGVEPERC
LAVEDSRRGLDSAVAAGLRCIAVPNALTRVQRFDSAHAVEADVSGVLKHVNAGKCPAGGGW

Specific function: Reversible Transformation Of Glucose 6-Phosphate And Beta-Glucose 1-Phosphate (By Similarity). [C]

COG id: COG0637

COG function: function code R; Predicted phosphatase/phosphohexomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Escherichia coli, GI1787576, Length=200, Percent_Identity=26, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788021, Length=203, Percent_Identity=29.064039408867, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1789046, Length=179, Percent_Identity=26.2569832402235, Blast_Score=62, Evalue=2e-11,
Organism=Escherichia coli, GI1789787, Length=124, Percent_Identity=32.258064516129, Blast_Score=62, Evalue=2e-11,
Organism=Drosophila melanogaster, GI116008157, Length=206, Percent_Identity=28.6407766990291, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: 5.4.2.6 [C]

Molecular weight: Translated: 24367; Mature: 24367

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEAILWDNDGLLVDSETVFFEMTRRFFADAGLTIDEEFWGIEYLGNARHSGELARELGL
CCEEEEECCCCEEEECHHHHHHHHHHHHHHCCCEECHHHCCHHHHCCCCHHHHHHHHHCH
AEELVRPLLDRRNAAFVERLQQPVPLMPKVRETIEALSGTVRLAVVTGSDRDKVMLMHAA
HHHHHHHHHCCCCHHHHHHHCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCEEEEHHHH
HGLLDHFEVIVTSDEVKNPKPHPEPYFKAMELLGVEPERCLAVEDSRRGLDSAVAAGLRC
HHHHHHHHEEEECCCCCCCCCCCCHHHHHHHHHCCCHHHEEEECHHHCCHHHHHHHCEEE
IAVPNALTRVQRFDSAHAVEADVSGVLKHVNAGKCPAGGGW
EECCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MIEAILWDNDGLLVDSETVFFEMTRRFFADAGLTIDEEFWGIEYLGNARHSGELARELGL
CCEEEEECCCCEEEECHHHHHHHHHHHHHHCCCEECHHHCCHHHHCCCCHHHHHHHHHCH
AEELVRPLLDRRNAAFVERLQQPVPLMPKVRETIEALSGTVRLAVVTGSDRDKVMLMHAA
HHHHHHHHHCCCCHHHHHHHCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCEEEEHHHH
HGLLDHFEVIVTSDEVKNPKPHPEPYFKAMELLGVEPERCLAVEDSRRGLDSAVAAGLRC
HHHHHHHHEEEECCCCCCCCCCCCHHHHHHHHHCCCHHHEEEECHHHCCHHHHHHHCEEE
IAVPNALTRVQRFDSAHAVEADVSGVLKHVNAGKCPAGGGW
EECCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Beta-D-Glucose 1-Phosphate [C]

Specific reaction: Beta-D-Glucose 1-Phosphate = Beta-D-Glucose 6- Phosphate. [C]

General reaction: Group transfer (intramolecular phosphate group isomerization [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969498; 9384377 [H]