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The map label for this gene is acpS

Identifier: 193211951

GI number: 193211951

Start: 295426

End: 295779

Strand: Direct

Name: acpS

Synonym: Cpar_0277

Alternate gene names: 193211951

Gene position: 295426-295779 (Clockwise)

Preceding gene: 193211950

Following gene: 193211954

Centisome position: 12.9

GC content: 61.3

Gene sequence:

>354_bases
ATGGAAATCGGGGTTGACATCGTTGAAATCGCCCGCATCCGGGCCGTGTACGAACGCTCCGGCAAGGCTTTCATGAACAA
GGTGCTGACCGCTGCCGAAATCGAGCAGTGCCTTGCCAAGCCCGATCCCGCAGTAAGCCTTGCAGGACGCTTTGCCGCCA
AGGAGGCGATTTCCAAAGCGCTCGGCTCCGGCATCGGTCATAAGCTTGGCTGGCATTCCATCGAAGTGCTGAACAACGAA
GCGGGCAAGCCCGAGGTGACGCTTCATGCCCCGCACCTTTCCTACCGGGTCAGCATCTCCATCTCCCACGACCGCCACTC
CGCCGTGGCGATGGCGCTCGTGCAGCCGCTCTGA

Upstream 100 bases:

>100_bases
CGCGCTGACCGGCGTCGATTACATCTCCATCGGCGAGCTGACGCACAGCGTCAAGGCGCTCGACCTCTCCATGAAAATCG
AACGTACCTGACGATTCTGC

Downstream 100 bases:

>100_bases
ATCCGGGTTACAGAGACATAAAAAAAGGGCTCATCGTTGTCGATGAGCCCTTTTTGCAATAGCTGCGGACGAACCGCGTA
TCGGGTCGAGTCCGATTAGC

Product: 4'-phosphopantetheinyl transferase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS

Number of amino acids: Translated: 117; Mature: 117

Protein sequence:

>117_residues
MEIGVDIVEIARIRAVYERSGKAFMNKVLTAAEIEQCLAKPDPAVSLAGRFAAKEAISKALGSGIGHKLGWHSIEVLNNE
AGKPEVTLHAPHLSYRVSISISHDRHSAVAMALVQPL

Sequences:

>Translated_117_residues
MEIGVDIVEIARIRAVYERSGKAFMNKVLTAAEIEQCLAKPDPAVSLAGRFAAKEAISKALGSGIGHKLGWHSIEVLNNE
AGKPEVTLHAPHLSYRVSISISHDRHSAVAMALVQPL
>Mature_117_residues
MEIGVDIVEIARIRAVYERSGKAFMNKVLTAAEIEQCLAKPDPAVSLAGRFAAKEAISKALGSGIGHKLGWHSIEVLNNE
AGKPEVTLHAPHLSYRVSISISHDRHSAVAMALVQPL

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family

Homologues:

Organism=Escherichia coli, GI1788916, Length=120, Percent_Identity=37.5, Blast_Score=77, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPS_CHLP8 (B3QR46)

Other databases:

- EMBL:   CP001099
- RefSeq:   YP_001997904.1
- GeneID:   6419190
- GenomeReviews:   CP001099_GR
- KEGG:   cpc:Cpar_0277
- HOGENOM:   HBG734479
- OMA:   NSSAIAY
- ProtClustDB:   PRK00070
- GO:   GO:0005737
- HAMAP:   MF_00101
- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282
- TIGRFAMs:   TIGR00516
- TIGRFAMs:   TIGR00556

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: =2.7.8.7

Molecular weight: Translated: 12563; Mature: 12563

Theoretical pI: Translated: 8.52; Mature: 8.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIGVDIVEIARIRAVYERSGKAFMNKVLTAAEIEQCLAKPDPAVSLAGRFAAKEAISKA
CCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
LGSGIGHKLGWHSIEVLNNEAGKPEVTLHAPHLSYRVSISISHDRHSAVAMALVQPL
HHCCCCCCCCCHHEEEECCCCCCCEEEEECCCEEEEEEEEECCCCHHHHHHHHHCCC
>Mature Secondary Structure
MEIGVDIVEIARIRAVYERSGKAFMNKVLTAAEIEQCLAKPDPAVSLAGRFAAKEAISKA
CCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
LGSGIGHKLGWHSIEVLNNEAGKPEVTLHAPHLSYRVSISISHDRHSAVAMALVQPL
HHCCCCCCCCCHHEEEECCCCCCCEEEEECCCEEEEEEEEECCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA