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The map label for this gene is dfrA [H]

Identifier: 193211954

GI number: 193211954

Start: 298777

End: 299778

Strand: Direct

Name: dfrA [H]

Synonym: Cpar_0280

Alternate gene names: 193211954

Gene position: 298777-299778 (Clockwise)

Preceding gene: 193211951

Following gene: 193211955

Centisome position: 13.05

GC content: 59.78

Gene sequence:

>1002_bases
ATGTCAGCAATTCCGATACTCATTACCGGTGCAACGGGTTACATAGGTTCACGGCTTCTGCTTGATCTTATCGGCAGGTT
CGGTGAAGGCGTGCGTTGCCGAGTTGCGGTCAGAGCGGGTTCGGACGCTTCGTTCCTCAAGGGCTTTCCGGTCGAGATCG
TTCGCGCGGATGTGCACGATCCAATCGCCATTGGAGAAGCGGTCAAGGGGATGGAGGTGGTGTTTCACTGCGCTGGAATG
ATCGCTTTTACCAGCAACTTCCGCAACCGGTTGCATGATACCAACGTGCTTGGCACTCGCCATGTGGTCGATTCGTGCCT
TGAACACGGCGTGAAGCGCATGGTGATGACCAGCTCGATTGCCGCTGTCGGTTCCGAGACCGTGGATGGCGTCGTTGTTG
AATCCACCGAGCACTCCACGTTTACCGAATGGCAGCGCCACAACGTTTATATGGAGTCCAAGCACCTGGCCGAACTCGAA
TGCCGGCGCGGCCTGGCTGAAGGGCTCGACGTGGTGATGGTCAATCCCGGCGTGGTGATCGGCCGGAACCCGGAGCCGGG
TATGCCCGTCAGTTCATCGAACGAAACCTTGCGCCTGATCTACGAGGGGCGCGTGCCGTTCTGTCCTGAAGGATCGACTG
GCTTTGTTGACGTCAGGGATGCGGCAGACGCCCATATCGCAGCGTGGACGAAGGGGAAATCGGGCGAGCGCTACATCATT
GTCGGTGAAAATCTCTCCTTCCGGGAGCTGTTCAGCCGCATCGCCGCTCTGCCTGGCAGCCGCACCGGCAAGCCGATGGT
CGTCGGCAACTTGGCCGGAGCTGCAGCCGGAGCTGGCGGCGAGCTCTTTTCGATGCTGACCGGACGCCCTTCGTTCGTCA
GCATCGAGAGCATTCGGCAGGCTTCGCGTTCCGCTCGGTTCAGCAACCTGCGCTCGATTCAGGAGCTTGGCATCAGCTAC
CGGCCGTTTGACGAAACCCTCAGGAGCGCCGTGGCGTTGTAA

Upstream 100 bases:

>100_bases
ATTCGTTTTATTCTTCTTATTATTAAAAACAAATCGGCGCTGGGCCGCATCGCTTCACAGATGCCGGAGTTTTCAGAAGG
GCGCCACTGCTCCATCGTTC

Downstream 100 bases:

>100_bases
TCCGAATAGCAAATTTTCAATTCACATACCCCTACTATTTTCATGGATAAAGAGAACTCAAAGCAGACAGCACAGCCGCC
GGTGGTCGATCCGGCAAGGC

Product: NAD-dependent epimerase/dehydratase

Products: NA

Alternate protein names: DFR; Dihydrokaempferol 4-reductase [H]

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MSAIPILITGATGYIGSRLLLDLIGRFGEGVRCRVAVRAGSDASFLKGFPVEIVRADVHDPIAIGEAVKGMEVVFHCAGM
IAFTSNFRNRLHDTNVLGTRHVVDSCLEHGVKRMVMTSSIAAVGSETVDGVVVESTEHSTFTEWQRHNVYMESKHLAELE
CRRGLAEGLDVVMVNPGVVIGRNPEPGMPVSSSNETLRLIYEGRVPFCPEGSTGFVDVRDAADAHIAAWTKGKSGERYII
VGENLSFRELFSRIAALPGSRTGKPMVVGNLAGAAAGAGGELFSMLTGRPSFVSIESIRQASRSARFSNLRSIQELGISY
RPFDETLRSAVAL

Sequences:

>Translated_333_residues
MSAIPILITGATGYIGSRLLLDLIGRFGEGVRCRVAVRAGSDASFLKGFPVEIVRADVHDPIAIGEAVKGMEVVFHCAGM
IAFTSNFRNRLHDTNVLGTRHVVDSCLEHGVKRMVMTSSIAAVGSETVDGVVVESTEHSTFTEWQRHNVYMESKHLAELE
CRRGLAEGLDVVMVNPGVVIGRNPEPGMPVSSSNETLRLIYEGRVPFCPEGSTGFVDVRDAADAHIAAWTKGKSGERYII
VGENLSFRELFSRIAALPGSRTGKPMVVGNLAGAAAGAGGELFSMLTGRPSFVSIESIRQASRSARFSNLRSIQELGISY
RPFDETLRSAVAL
>Mature_332_residues
SAIPILITGATGYIGSRLLLDLIGRFGEGVRCRVAVRAGSDASFLKGFPVEIVRADVHDPIAIGEAVKGMEVVFHCAGMI
AFTSNFRNRLHDTNVLGTRHVVDSCLEHGVKRMVMTSSIAAVGSETVDGVVVESTEHSTFTEWQRHNVYMESKHLAELEC
RRGLAEGLDVVMVNPGVVIGRNPEPGMPVSSSNETLRLIYEGRVPFCPEGSTGFVDVRDAADAHIAAWTKGKSGERYIIV
GENLSFRELFSRIAALPGSRTGKPMVVGNLAGAAAGAGGELFSMLTGRPSFVSIESIRQASRSARFSNLRSIQELGISYR
PFDETLRSAVAL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydroflavonol-4-reductase family [H]

Homologues:

Organism=Caenorhabditis elegans, GI71987463, Length=249, Percent_Identity=29.3172690763052, Blast_Score=76, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR017829
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =1.1.1.219 [H]

Molecular weight: Translated: 35836; Mature: 35705

Theoretical pI: Translated: 7.27; Mature: 7.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAIPILITGATGYIGSRLLLDLIGRFGEGVRCRVAVRAGSDASFLKGFPVEIVRADVHD
CCCCEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHCCCCCEEEEECCCC
PIAIGEAVKGMEVVFHCAGMIAFTSNFRNRLHDTNVLGTRHVVDSCLEHGVKRMVMTSSI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AAVGSETVDGVVVESTEHSTFTEWQRHNVYMESKHLAELECRRGLAEGLDVVMVNPGVVI
HHHCCCCCCCEEEECCCCCHHHHHHHCCCEECCCHHHHHHHHHHHHCCCEEEEECCCEEE
GRNPEPGMPVSSSNETLRLIYEGRVPFCPEGSTGFVDVRDAADAHIAAWTKGKSGERYII
CCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCEEEECCCCCCEEEEEECCCCCCEEEE
VGENLSFRELFSRIAALPGSRTGKPMVVGNLAGAAAGAGGELFSMLTGRPSFVSIESIRQ
ECCCCCHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCHHHHHHHCCCCCEEEHHHHHH
ASRSARFSNLRSIQELGISYRPFDETLRSAVAL
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
SAIPILITGATGYIGSRLLLDLIGRFGEGVRCRVAVRAGSDASFLKGFPVEIVRADVHD
CCCEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHCCCCCEEEEECCCC
PIAIGEAVKGMEVVFHCAGMIAFTSNFRNRLHDTNVLGTRHVVDSCLEHGVKRMVMTSSI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AAVGSETVDGVVVESTEHSTFTEWQRHNVYMESKHLAELECRRGLAEGLDVVMVNPGVVI
HHHCCCCCCCEEEECCCCCHHHHHHHCCCEECCCHHHHHHHHHHHHCCCEEEEECCCEEE
GRNPEPGMPVSSSNETLRLIYEGRVPFCPEGSTGFVDVRDAADAHIAAWTKGKSGERYII
CCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCEEEECCCCCCEEEEEECCCCCCEEEE
VGENLSFRELFSRIAALPGSRTGKPMVVGNLAGAAAGAGGELFSMLTGRPSFVSIESIRQ
ECCCCCHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCHHHHHHHCCCCCEEEHHHHHH
ASRSARFSNLRSIQELGISYRPFDETLRSAVAL
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]